Electron Transport Chain (see tricarboxylic acid section for Complex II), Cytochrome c oxidase assembly factor-like
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005739 | mitochondrion | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 3 |
| GO:0016020 | membrane | 2 | 2 |
Related structures:
AlphaFold database: A4HYS6
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0008535 | respiratory chain complex IV assembly | 7 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016043 | cellular component organization | 3 | 1 |
| GO:0017004 | cytochrome complex assembly | 6 | 1 |
| GO:0022607 | cellular component assembly | 4 | 1 |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 6 | 1 |
| GO:0033617 | mitochondrial cytochrome c oxidase assembly | 7 | 1 |
| GO:0043933 | protein-containing complex organization | 4 | 1 |
| GO:0065003 | protein-containing complex assembly | 5 | 1 |
| GO:0071840 | cellular component organization or biogenesis | 2 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 4 |
| GO:0016491 | oxidoreductase activity | 2 | 4 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 159 | 163 | PF00656 | 0.303 |
| CLV_NRD_NRD_1 | 123 | 125 | PF00675 | 0.360 |
| CLV_NRD_NRD_1 | 6 | 8 | PF00675 | 0.618 |
| CLV_PCSK_SKI1_1 | 196 | 200 | PF00082 | 0.342 |
| CLV_PCSK_SKI1_1 | 226 | 230 | PF00082 | 0.466 |
| CLV_PCSK_SKI1_1 | 45 | 49 | PF00082 | 0.372 |
| DEG_MDM2_SWIB_1 | 53 | 60 | PF02201 | 0.251 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.576 |
| DEG_ODPH_VHL_1 | 14 | 26 | PF01847 | 0.522 |
| DOC_CYCLIN_yClb1_LxF_4 | 72 | 78 | PF00134 | 0.321 |
| DOC_CYCLIN_yCln2_LP_2 | 32 | 38 | PF00134 | 0.251 |
| DOC_MAPK_MEF2A_6 | 100 | 109 | PF00069 | 0.289 |
| LIG_BRCT_BRCA1_1 | 107 | 111 | PF00533 | 0.345 |
| LIG_FHA_2 | 134 | 140 | PF00498 | 0.345 |
| LIG_FHA_2 | 155 | 161 | PF00498 | 0.266 |
| LIG_FHA_2 | 46 | 52 | PF00498 | 0.281 |
| LIG_LIR_Gen_1 | 17 | 26 | PF02991 | 0.548 |
| LIG_LIR_Nem_3 | 58 | 64 | PF02991 | 0.284 |
| LIG_MYND_1 | 12 | 16 | PF01753 | 0.497 |
| LIG_Pex14_1 | 147 | 151 | PF04695 | 0.251 |
| LIG_Pex14_1 | 57 | 61 | PF04695 | 0.257 |
| LIG_Pex14_2 | 53 | 57 | PF04695 | 0.289 |
| LIG_REV1ctd_RIR_1 | 196 | 205 | PF16727 | 0.373 |
| LIG_SH2_GRB2like | 4 | 7 | PF00017 | 0.620 |
| LIG_SH2_NCK_1 | 151 | 155 | PF00017 | 0.266 |
| LIG_SH2_NCK_1 | 216 | 220 | PF00017 | 0.527 |
| LIG_SH2_STAP1 | 216 | 220 | PF00017 | 0.527 |
| LIG_SH2_STAT5 | 187 | 190 | PF00017 | 0.262 |
| LIG_SH2_STAT5 | 46 | 49 | PF00017 | 0.266 |
| LIG_SH2_STAT5 | 61 | 64 | PF00017 | 0.251 |
| LIG_SH3_3 | 166 | 172 | PF00018 | 0.345 |
| LIG_SH3_4 | 27 | 34 | PF00018 | 0.518 |
| LIG_TRAF2_1 | 136 | 139 | PF00917 | 0.377 |
| LIG_TRAF2_1 | 157 | 160 | PF00917 | 0.260 |
| LIG_TRAF2_1 | 96 | 99 | PF00917 | 0.397 |
| LIG_TYR_ITIM | 149 | 154 | PF00017 | 0.266 |
| LIG_TYR_ITIM | 214 | 219 | PF00017 | 0.499 |
| MOD_CK1_1 | 20 | 26 | PF00069 | 0.545 |
| MOD_CK1_1 | 65 | 71 | PF00069 | 0.277 |
| MOD_CK2_1 | 133 | 139 | PF00069 | 0.320 |
| MOD_CK2_1 | 150 | 156 | PF00069 | 0.160 |
| MOD_CK2_1 | 45 | 51 | PF00069 | 0.281 |
| MOD_GlcNHglycan | 183 | 186 | PF01048 | 0.266 |
| MOD_GSK3_1 | 150 | 157 | PF00069 | 0.251 |
| MOD_GSK3_1 | 222 | 229 | PF00069 | 0.499 |
| MOD_N-GLC_1 | 205 | 210 | PF02516 | 0.328 |
| MOD_NEK2_1 | 180 | 185 | PF00069 | 0.273 |
| MOD_NEK2_1 | 205 | 210 | PF00069 | 0.515 |
| MOD_NEK2_1 | 222 | 227 | PF00069 | 0.507 |
| MOD_NEK2_1 | 38 | 43 | PF00069 | 0.294 |
| MOD_NEK2_1 | 62 | 67 | PF00069 | 0.264 |
| MOD_PIKK_1 | 27 | 33 | PF00454 | 0.501 |
| MOD_PKA_2 | 38 | 44 | PF00069 | 0.270 |
| MOD_Plk_1 | 174 | 180 | PF00069 | 0.252 |
| MOD_Plk_1 | 205 | 211 | PF00069 | 0.331 |
| MOD_SUMO_rev_2 | 86 | 96 | PF00179 | 0.319 |
| TRG_ENDOCYTIC_2 | 151 | 154 | PF00928 | 0.266 |
| TRG_ENDOCYTIC_2 | 216 | 219 | PF00928 | 0.510 |
| TRG_ENDOCYTIC_2 | 61 | 64 | PF00928 | 0.251 |
| TRG_ER_diArg_1 | 128 | 131 | PF00400 | 0.266 |
| TRG_ER_diArg_1 | 36 | 39 | PF00400 | 0.286 |
| TRG_Pf-PMV_PEXEL_1 | 76 | 80 | PF00026 | 0.376 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P3R3 | Leptomonas seymouri | 30% | 75% |
| A0A0N1I6S1 | Leptomonas seymouri | 79% | 82% |
| A0A0S4J8R8 | Bodo saltans | 31% | 78% |
| A0A0S4KH84 | Bodo saltans | 60% | 71% |
| A0A1X0NLN8 | Trypanosomatidae | 31% | 86% |
| A0A1X0NWD3 | Trypanosomatidae | 68% | 77% |
| A0A3R7L4G0 | Trypanosoma rangeli | 69% | 80% |
| A0A3R7RML7 | Trypanosoma rangeli | 32% | 100% |
| A0A3S5H5E9 | Leishmania donovani | 30% | 75% |
| A0A3S5H786 | Leishmania donovani | 99% | 100% |
| A1A4J8 | Bos taurus | 34% | 76% |
| A4H427 | Leishmania braziliensis | 29% | 100% |
| A4HF41 | Leishmania braziliensis | 32% | 100% |
| A4HSB1 | Leishmania infantum | 30% | 100% |
| A6H784 | Bos taurus | 33% | 87% |
| C9ZI98 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 70% | 77% |
| C9ZYA3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 29% | 85% |
| E9AID5 | Leishmania braziliensis | 87% | 100% |
| E9AK94 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 29% | 100% |
| E9AUM2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 95% | 100% |
| E9AYH7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 32% | 100% |
| O42899 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 29% | 88% |
| O43819 | Homo sapiens | 31% | 87% |
| O75880 | Homo sapiens | 34% | 77% |
| O97196 | Leishmania major | 31% | 100% |
| P23833 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 32% | 78% |
| P38072 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 31% | 77% |
| P47206 | Pseudonocardia sediminis | 25% | 100% |
| Q1RIN4 | Rickettsia bellii (strain RML369-C) | 30% | 100% |
| Q4Q8Z5 | Leishmania major | 32% | 100% |
| Q4QCW2 | Leishmania major | 97% | 100% |
| Q4UKW2 | Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) | 28% | 100% |
| Q52720 | Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) | 31% | 100% |
| Q5RH02 | Danio rerio | 35% | 83% |
| Q5SUC9 | Mus musculus | 34% | 81% |
| Q68WF1 | Rickettsia typhi (strain ATCC VR-144 / Wilmington) | 24% | 100% |
| Q8LAL0 | Arabidopsis thaliana | 28% | 84% |
| Q8VCL2 | Mus musculus | 34% | 91% |
| Q8VYP0 | Arabidopsis thaliana | 32% | 69% |
| Q92H76 | Rickettsia conorii (strain ATCC VR-613 / Malish 7) | 27% | 100% |
| Q9ZCW7 | Rickettsia prowazekii (strain Madrid E) | 27% | 100% |
| V5BI84 | Trypanosoma cruzi | 31% | 86% |
| V5BQS4 | Trypanosoma cruzi | 68% | 69% |