LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
unspecified product
Species:
Leishmania infantum
UniProt:
A4HYS1_LEIIN
TriTrypDb:
LINF_200008550 *
Length:
127

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HYS1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HYS1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 122 124 PF00675 0.750
CLV_NRD_NRD_1 56 58 PF00675 0.733
CLV_PCSK_KEX2_1 122 124 PF00082 0.768
CLV_PCSK_KEX2_1 56 58 PF00082 0.733
CLV_PCSK_SKI1_1 17 21 PF00082 0.602
DEG_APCC_DBOX_1 12 20 PF00400 0.602
DOC_CKS1_1 2 7 PF01111 0.612
DOC_WW_Pin1_4 1 6 PF00397 0.619
DOC_WW_Pin1_4 117 122 PF00397 0.687
LIG_14-3-3_CanoR_1 37 41 PF00244 0.657
LIG_14-3-3_CanoR_1 48 52 PF00244 0.541
LIG_SH2_STAT5 73 76 PF00017 0.594
LIG_SH3_3 37 43 PF00018 0.608
LIG_SH3_3 55 61 PF00018 0.656
MOD_CDC14_SPxK_1 120 123 PF00782 0.698
MOD_CDK_SPK_2 117 122 PF00069 0.687
MOD_CDK_SPxK_1 117 123 PF00069 0.691
MOD_CK1_1 7 13 PF00069 0.598
MOD_DYRK1A_RPxSP_1 117 121 PF00069 0.613
MOD_GlcNHglycan 27 30 PF01048 0.662
MOD_GSK3_1 17 24 PF00069 0.707
MOD_GSK3_1 4 11 PF00069 0.601
MOD_GSK3_1 65 72 PF00069 0.630
MOD_LATS_1 15 21 PF00433 0.603
MOD_NEK2_1 19 24 PF00069 0.632
MOD_NEK2_1 36 41 PF00069 0.583
MOD_NEK2_1 69 74 PF00069 0.607
MOD_PKA_2 36 42 PF00069 0.732
MOD_PKA_2 47 53 PF00069 0.660
MOD_PKA_2 75 81 PF00069 0.744
MOD_Plk_4 36 42 PF00069 0.596
MOD_ProDKin_1 1 7 PF00069 0.617
MOD_ProDKin_1 117 123 PF00069 0.691
TRG_ER_diArg_1 121 123 PF00400 0.755
TRG_ER_diArg_1 56 59 PF00400 0.787

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WVU3 Leishmania donovani 100% 100%
E9AUH6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 100%
Q4QD08 Leishmania major 63% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS