LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HYR6_LEIIN
TriTrypDb:
LINF_200009900
Length:
96

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HYR6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HYR6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 13 15 PF00675 0.613
CLV_NRD_NRD_1 81 83 PF00675 0.597
CLV_PCSK_KEX2_1 12 14 PF00082 0.621
CLV_PCSK_KEX2_1 81 83 PF00082 0.597
DEG_Nend_UBRbox_3 1 3 PF02207 0.579
DEG_SCF_FBW7_1 60 67 PF00400 0.520
DOC_CKS1_1 61 66 PF01111 0.518
DOC_USP7_MATH_1 64 68 PF00917 0.666
DOC_USP7_UBL2_3 89 93 PF12436 0.608
DOC_WW_Pin1_4 60 65 PF00397 0.588
DOC_WW_Pin1_4 73 78 PF00397 0.475
LIG_14-3-3_CanoR_1 52 61 PF00244 0.505
LIG_Actin_WH2_2 66 83 PF00022 0.504
LIG_FHA_1 54 60 PF00498 0.505
LIG_FHA_1 61 67 PF00498 0.618
LIG_FHA_2 29 35 PF00498 0.700
LIG_FHA_2 86 92 PF00498 0.602
LIG_LIR_Gen_1 56 66 PF02991 0.464
LIG_LIR_Nem_3 56 61 PF02991 0.513
LIG_SH2_STAT5 45 48 PF00017 0.475
LIG_SH3_2 18 23 PF14604 0.607
LIG_SH3_3 15 21 PF00018 0.589
LIG_SH3_3 58 64 PF00018 0.519
LIG_WRC_WIRS_1 65 70 PF05994 0.508
MOD_CK2_1 85 91 PF00069 0.603
MOD_GlcNHglycan 82 85 PF01048 0.770
MOD_GSK3_1 60 67 PF00069 0.545
MOD_GSK3_1 69 76 PF00069 0.486
MOD_NEK2_1 80 85 PF00069 0.626
MOD_PIKK_1 38 44 PF00454 0.573
MOD_PKA_2 80 86 PF00069 0.690
MOD_Plk_4 64 70 PF00069 0.589
MOD_ProDKin_1 60 66 PF00069 0.590
MOD_ProDKin_1 73 79 PF00069 0.479
MOD_SUMO_rev_2 29 37 PF00179 0.702
TRG_ER_diArg_1 12 14 PF00400 0.624
TRG_ER_diArg_1 49 52 PF00400 0.534
TRG_ER_diArg_1 80 82 PF00400 0.598

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HW26 Leptomonas seymouri 47% 100%
A0A3Q8IKG3 Leishmania donovani 100% 100%
E9AUI9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 71%
Q4QCZ5 Leishmania major 85% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS