LeishMANIAdb
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37S ribosomal protein S24, mitochondrial

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
37S ribosomal protein S24, mitochondrial
Gene product:
SSU ribosomal protein - mitochondrial - putative
Species:
Leishmania infantum
UniProt:
A4HYR0_LEIIN
TriTrypDb:
LINF_200010500
Length:
429

Annotations

Annotations by Jardim et al.

Ribosomal Protein, SSU ribosomal , mitochondrial, putative (MRPS15) Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 5
GO:0032991 protein-containing complex 1 6
GO:0043226 organelle 2 5
GO:0043228 non-membrane-bounded organelle 3 5
GO:0043229 intracellular organelle 3 5
GO:0043232 intracellular non-membrane-bounded organelle 4 5
GO:0110165 cellular anatomical entity 1 5
GO:1990904 ribonucleoprotein complex 2 6
GO:0000314 organellar small ribosomal subunit 5 1
GO:0005763 mitochondrial small ribosomal subunit 3 1
GO:0015935 small ribosomal subunit 4 1
GO:0044391 ribosomal subunit 3 1
GO:0098798 mitochondrial protein-containing complex 2 1

Expansion

Sequence features

A4HYR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HYR0

PDB structure(s): 7ane_i

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 6
GO:0006518 peptide metabolic process 4 6
GO:0006807 nitrogen compound metabolic process 2 6
GO:0008152 metabolic process 1 6
GO:0009058 biosynthetic process 2 6
GO:0009059 macromolecule biosynthetic process 4 6
GO:0009987 cellular process 1 6
GO:0019538 protein metabolic process 3 6
GO:0034641 cellular nitrogen compound metabolic process 3 6
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 6
GO:0043043 peptide biosynthetic process 5 6
GO:0043170 macromolecule metabolic process 3 6
GO:0043603 amide metabolic process 3 6
GO:0043604 amide biosynthetic process 4 6
GO:0044237 cellular metabolic process 2 6
GO:0044238 primary metabolic process 2 6
GO:0044249 cellular biosynthetic process 3 6
GO:0044260 obsolete cellular macromolecule metabolic process 3 6
GO:0044271 cellular nitrogen compound biosynthetic process 4 6
GO:0071704 organic substance metabolic process 2 6
GO:1901564 organonitrogen compound metabolic process 3 6
GO:1901566 organonitrogen compound biosynthetic process 4 6
GO:1901576 organic substance biosynthetic process 3 6
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 6
GO:0005198 structural molecule activity 1 6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 40 44 PF00656 0.540
CLV_NRD_NRD_1 13 15 PF00675 0.677
CLV_NRD_NRD_1 163 165 PF00675 0.426
CLV_NRD_NRD_1 256 258 PF00675 0.414
CLV_NRD_NRD_1 264 266 PF00675 0.347
CLV_NRD_NRD_1 387 389 PF00675 0.436
CLV_NRD_NRD_1 410 412 PF00675 0.452
CLV_NRD_NRD_1 55 57 PF00675 0.534
CLV_NRD_NRD_1 79 81 PF00675 0.493
CLV_PCSK_KEX2_1 163 165 PF00082 0.400
CLV_PCSK_KEX2_1 227 229 PF00082 0.385
CLV_PCSK_KEX2_1 264 266 PF00082 0.427
CLV_PCSK_KEX2_1 272 274 PF00082 0.439
CLV_PCSK_KEX2_1 424 426 PF00082 0.450
CLV_PCSK_KEX2_1 55 57 PF00082 0.538
CLV_PCSK_PC1ET2_1 227 229 PF00082 0.385
CLV_PCSK_PC1ET2_1 272 274 PF00082 0.546
CLV_PCSK_PC1ET2_1 424 426 PF00082 0.450
CLV_PCSK_PC7_1 420 426 PF00082 0.446
CLV_PCSK_SKI1_1 186 190 PF00082 0.417
CLV_PCSK_SKI1_1 227 231 PF00082 0.381
CLV_PCSK_SKI1_1 249 253 PF00082 0.414
CLV_PCSK_SKI1_1 366 370 PF00082 0.422
CLV_PCSK_SKI1_1 411 415 PF00082 0.447
CLV_PCSK_SKI1_1 94 98 PF00082 0.419
DEG_MDM2_SWIB_1 271 278 PF02201 0.370
DOC_CKS1_1 85 90 PF01111 0.478
DOC_CYCLIN_RxL_1 408 416 PF00134 0.443
DOC_MAPK_gen_1 227 234 PF00069 0.481
DOC_MAPK_gen_1 264 271 PF00069 0.394
DOC_MAPK_gen_1 385 395 PF00069 0.478
DOC_MAPK_MEF2A_6 227 234 PF00069 0.481
DOC_MAPK_MEF2A_6 388 397 PF00069 0.485
DOC_PP1_RVXF_1 265 272 PF00149 0.403
DOC_PP2B_LxvP_1 287 290 PF13499 0.499
DOC_PP4_FxxP_1 171 174 PF00568 0.399
DOC_SPAK_OSR1_1 170 174 PF12202 0.399
DOC_USP7_UBL2_3 227 231 PF12436 0.384
DOC_USP7_UBL2_3 268 272 PF12436 0.410
DOC_USP7_UBL2_3 396 400 PF12436 0.490
DOC_WW_Pin1_4 105 110 PF00397 0.425
DOC_WW_Pin1_4 217 222 PF00397 0.388
DOC_WW_Pin1_4 84 89 PF00397 0.470
LIG_14-3-3_CanoR_1 170 174 PF00244 0.523
LIG_14-3-3_CanoR_1 332 341 PF00244 0.414
LIG_14-3-3_CanoR_1 420 428 PF00244 0.525
LIG_14-3-3_CanoR_1 55 61 PF00244 0.514
LIG_BRCT_BRCA1_1 390 394 PF00533 0.439
LIG_BRCT_BRCA1_2 390 396 PF00533 0.441
LIG_CtBP_PxDLS_1 289 293 PF00389 0.501
LIG_FHA_1 173 179 PF00498 0.468
LIG_FHA_1 3 9 PF00498 0.662
LIG_FHA_1 344 350 PF00498 0.447
LIG_FHA_2 193 199 PF00498 0.519
LIG_LIR_Apic_2 168 174 PF02991 0.397
LIG_LIR_Apic_2 344 348 PF02991 0.442
LIG_LIR_Gen_1 23 31 PF02991 0.706
LIG_LIR_Gen_1 391 399 PF02991 0.463
LIG_LIR_Nem_3 23 28 PF02991 0.720
LIG_LIR_Nem_3 270 274 PF02991 0.383
LIG_LIR_Nem_3 299 303 PF02991 0.403
LIG_LIR_Nem_3 408 413 PF02991 0.391
LIG_Pex14_1 156 160 PF04695 0.382
LIG_Pex14_2 271 275 PF04695 0.400
LIG_Pex14_2 386 390 PF04695 0.428
LIG_SH2_CRK 345 349 PF00017 0.433
LIG_SH2_CRK 410 414 PF00017 0.434
LIG_SH2_SRC 211 214 PF00017 0.415
LIG_SH2_STAP1 167 171 PF00017 0.407
LIG_SH2_STAP1 303 307 PF00017 0.418
LIG_SH2_STAP1 364 368 PF00017 0.403
LIG_SH2_STAP1 4 8 PF00017 0.616
LIG_SH2_STAT5 345 348 PF00017 0.453
LIG_SH2_STAT5 4 7 PF00017 0.613
LIG_SH3_1 80 86 PF00018 0.418
LIG_SH3_3 119 125 PF00018 0.441
LIG_SH3_3 283 289 PF00018 0.455
LIG_SH3_3 315 321 PF00018 0.439
LIG_SH3_3 401 407 PF00018 0.425
LIG_SH3_3 80 86 PF00018 0.418
LIG_TRAF2_1 195 198 PF00917 0.426
LIG_TRAF2_1 348 351 PF00917 0.566
LIG_TRAF2_1 64 67 PF00917 0.530
LIG_TYR_ITIM 362 367 PF00017 0.431
LIG_UBA3_1 103 112 PF00899 0.535
LIG_UBA3_1 193 199 PF00899 0.439
LIG_UBA3_1 393 400 PF00899 0.491
MOD_CDK_SPxxK_3 105 112 PF00069 0.411
MOD_CK1_1 172 178 PF00069 0.453
MOD_CK1_1 192 198 PF00069 0.425
MOD_CK1_1 23 29 PF00069 0.731
MOD_CK1_1 3 9 PF00069 0.662
MOD_CK2_1 192 198 PF00069 0.405
MOD_CK2_1 330 336 PF00069 0.435
MOD_CMANNOS 76 79 PF00535 0.429
MOD_GlcNHglycan 390 393 PF01048 0.444
MOD_GlcNHglycan 400 403 PF01048 0.429
MOD_GlcNHglycan 5 8 PF01048 0.575
MOD_GlcNHglycan 58 61 PF01048 0.537
MOD_LATS_1 54 60 PF00433 0.642
MOD_N-GLC_1 105 110 PF02516 0.479
MOD_N-GLC_1 181 186 PF02516 0.441
MOD_N-GLC_1 23 28 PF02516 0.714
MOD_N-GLC_1 259 264 PF02516 0.493
MOD_N-GLC_2 325 327 PF02516 0.424
MOD_NEK2_1 138 143 PF00069 0.516
MOD_NEK2_1 189 194 PF00069 0.448
MOD_NEK2_1 216 221 PF00069 0.395
MOD_NEK2_1 259 264 PF00069 0.493
MOD_NEK2_1 309 314 PF00069 0.397
MOD_NEK2_1 341 346 PF00069 0.432
MOD_NEK2_1 413 418 PF00069 0.427
MOD_NEK2_2 181 186 PF00069 0.508
MOD_PIKK_1 310 316 PF00454 0.534
MOD_PIKK_1 413 419 PF00454 0.557
MOD_PIKK_1 89 95 PF00454 0.576
MOD_PKA_1 388 394 PF00069 0.437
MOD_PKA_2 169 175 PF00069 0.418
MOD_PKA_2 20 26 PF00069 0.708
MOD_PKA_2 419 425 PF00069 0.526
MOD_PKA_2 54 60 PF00069 0.520
MOD_Plk_1 181 187 PF00069 0.442
MOD_Plk_1 259 265 PF00069 0.497
MOD_Plk_4 189 195 PF00069 0.416
MOD_Plk_4 247 253 PF00069 0.449
MOD_Plk_4 296 302 PF00069 0.439
MOD_ProDKin_1 105 111 PF00069 0.417
MOD_ProDKin_1 217 223 PF00069 0.383
MOD_ProDKin_1 84 90 PF00069 0.474
MOD_SUMO_for_1 37 40 PF00179 0.625
MOD_SUMO_for_1 370 373 PF00179 0.420
MOD_SUMO_rev_2 351 357 PF00179 0.457
TRG_DiLeu_BaEn_2 381 387 PF01217 0.431
TRG_DiLeu_BaLyEn_6 134 139 PF01217 0.503
TRG_ENDOCYTIC_2 274 277 PF00928 0.354
TRG_ENDOCYTIC_2 364 367 PF00928 0.414
TRG_ENDOCYTIC_2 410 413 PF00928 0.442
TRG_ER_diArg_1 263 265 PF00400 0.448
TRG_ER_diArg_1 50 53 PF00400 0.550
TRG_Pf-PMV_PEXEL_1 347 351 PF00026 0.440
TRG_Pf-PMV_PEXEL_1 355 359 PF00026 0.425

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDF7 Leptomonas seymouri 90% 100%
A0A0S4J4D7 Bodo saltans 62% 100%
A0A1X0NWF9 Trypanosomatidae 82% 100%
A0A3S7WVW4 Leishmania donovani 100% 100%
A0A422NCH8 Trypanosoma rangeli 81% 100%
C9ZI69 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 80% 100%
E9AIA8 Leishmania braziliensis 94% 100%
E9AUJ5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4QCY9 Leishmania major 99% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS