LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HYQ4_LEIIN
TriTrypDb:
LINF_200011100
Length:
852

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 3
GO:0110165 cellular anatomical entity 1 3
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Expansion

Sequence features

A4HYQ4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HYQ4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 327 331 PF00656 0.409
CLV_C14_Caspase3-7 332 336 PF00656 0.408
CLV_C14_Caspase3-7 557 561 PF00656 0.565
CLV_NRD_NRD_1 428 430 PF00675 0.633
CLV_NRD_NRD_1 554 556 PF00675 0.727
CLV_NRD_NRD_1 691 693 PF00675 0.720
CLV_NRD_NRD_1 699 701 PF00675 0.677
CLV_NRD_NRD_1 780 782 PF00675 0.703
CLV_NRD_NRD_1 790 792 PF00675 0.680
CLV_NRD_NRD_1 86 88 PF00675 0.694
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WVX7 Leishmania donovani 97% 100%
E9AIB4 Leishmania braziliensis 56% 99%
E9AUK1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS