Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HYG5_LEIIN

TriTrypDb:

LINF_190020000

Length:

164

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HYG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HYG5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	155	157	PF00675	0.507
CLV_NRD_NRD_1	4	6	PF00675	0.686
CLV_PCSK_KEX2_1	4	6	PF00082	0.708
CLV_PCSK_SKI1_1	4	8	PF00082	0.680
DEG_Nend_Nbox_1	1	3	PF02207	0.690
DEG_SCF_FBW7_1	99	105	PF00400	0.484
DOC_CKS1_1	99	104	PF01111	0.486
DOC_CYCLIN_yCln2_LP_2	142	148	PF00134	0.454
DOC_MAPK_MEF2A_6	137	146	PF00069	0.461
DOC_PP2B_LxvP_1	142	145	PF13499	0.452
DOC_USP7_MATH_1	102	106	PF00917	0.518
DOC_USP7_MATH_1	130	134	PF00917	0.506
DOC_USP7_MATH_1	37	41	PF00917	0.629
DOC_WW_Pin1_4	131	136	PF00397	0.501
DOC_WW_Pin1_4	98	103	PF00397	0.546
LIG_14-3-3_CanoR_1	131	135	PF00244	0.504
LIG_14-3-3_CanoR_1	137	146	PF00244	0.440
LIG_14-3-3_CanoR_1	5	11	PF00244	0.669
LIG_BRCT_BRCA1_1	86	90	PF00533	0.503
LIG_FHA_1	44	50	PF00498	0.602
LIG_FHA_1	94	100	PF00498	0.498
LIG_LIR_Gen_1	105	113	PF02991	0.506
LIG_LIR_Nem_3	105	109	PF02991	0.518
LIG_LIR_Nem_3	87	93	PF02991	0.514
LIG_MYND_1	33	37	PF01753	0.666
LIG_SH3_1	124	130	PF00018	0.512
LIG_SH3_3	124	130	PF00018	0.512
LIG_SH3_3	86	92	PF00018	0.516
LIG_SH3_3	96	102	PF00018	0.545
LIG_SUMO_SIM_anti_2	105	111	PF11976	0.428
LIG_SUMO_SIM_par_1	95	101	PF11976	0.491
LIG_TRAF2_1	69	72	PF00917	0.574
LIG_UBA3_1	109	116	PF00899	0.429
LIG_UBA3_1	142	150	PF00899	0.454
LIG_WRC_WIRS_1	103	108	PF05994	0.516
MOD_CDC14_SPxK_1	134	137	PF00782	0.487
MOD_CDK_SPxK_1	131	137	PF00069	0.499
MOD_CK1_1	63	69	PF00069	0.681
MOD_CK1_1	81	87	PF00069	0.503
MOD_CK1_1	98	104	PF00069	0.551
MOD_CK2_1	102	108	PF00069	0.518
MOD_CK2_1	66	72	PF00069	0.589
MOD_Cter_Amidation	2	5	PF01082	0.684
MOD_DYRK1A_RPxSP_1	131	135	PF00069	0.504
MOD_GlcNHglycan	64	68	PF01048	0.625
MOD_GlcNHglycan	78	81	PF01048	0.551
MOD_GlcNHglycan	8	11	PF01048	0.650
MOD_GSK3_1	38	45	PF00069	0.682
MOD_GSK3_1	48	55	PF00069	0.614
MOD_GSK3_1	76	83	PF00069	0.519
MOD_GSK3_1	93	100	PF00069	0.520
MOD_NEK2_1	38	43	PF00069	0.600
MOD_NEK2_1	78	83	PF00069	0.532
MOD_NEK2_1	95	100	PF00069	0.496
MOD_PIKK_1	137	143	PF00454	0.463
MOD_PIKK_1	48	54	PF00454	0.603
MOD_PKA_2	130	136	PF00069	0.502
MOD_PKA_2	43	49	PF00069	0.629
MOD_Plk_1	71	77	PF00069	0.536
MOD_Plk_4	102	108	PF00069	0.518
MOD_Plk_4	84	90	PF00069	0.493
MOD_ProDKin_1	131	137	PF00069	0.499
MOD_ProDKin_1	98	104	PF00069	0.549
TRG_ER_diArg_1	4	6	PF00400	0.690

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IBH0	Leishmania donovani	53%	100%
A0A3S7WVJ6	Leishmania donovani	100%	100%
A4HA86	Leishmania braziliensis	74%	100%
E9AHU8	Leishmania infantum	52%	100%
E9AS83	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	100%
E9AS90	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QD74	Leishmania major	93%	99%
Q4QD83	Leishmania major	51%	100%