LeishMANIAdb
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Enkurin domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Enkurin domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HY72_LEIIN
TriTrypDb:
LINF_190009900
Length:
299

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HY72
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HY72

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 215 217 PF00675 0.728
CLV_NRD_NRD_1 42 44 PF00675 0.585
CLV_NRD_NRD_1 67 69 PF00675 0.660
CLV_NRD_NRD_1 75 77 PF00675 0.544
CLV_NRD_NRD_1 93 95 PF00675 0.503
CLV_PCSK_KEX2_1 215 217 PF00082 0.731
CLV_PCSK_KEX2_1 41 43 PF00082 0.585
CLV_PCSK_KEX2_1 67 69 PF00082 0.641
CLV_PCSK_KEX2_1 75 77 PF00082 0.540
CLV_PCSK_KEX2_1 93 95 PF00082 0.548
CLV_PCSK_PC7_1 211 217 PF00082 0.765
CLV_PCSK_SKI1_1 144 148 PF00082 0.563
CLV_PCSK_SKI1_1 166 170 PF00082 0.582
CLV_PCSK_SKI1_1 244 248 PF00082 0.698
DEG_APCC_DBOX_1 150 158 PF00400 0.601
DEG_APCC_DBOX_1 83 91 PF00400 0.544
DEG_Nend_UBRbox_2 1 3 PF02207 0.647
DOC_ANK_TNKS_1 184 191 PF00023 0.609
DOC_MAPK_gen_1 67 73 PF00069 0.508
DOC_MIT_MIM_1 162 171 PF04212 0.566
DOC_PP4_FxxP_1 117 120 PF00568 0.593
DOC_USP7_MATH_1 231 235 PF00917 0.748
DOC_USP7_UBL2_3 57 61 PF12436 0.562
DOC_WW_Pin1_4 225 230 PF00397 0.740
DOC_WW_Pin1_4 234 239 PF00397 0.699
DOC_WW_Pin1_4 9 14 PF00397 0.608
LIG_14-3-3_CanoR_1 171 177 PF00244 0.530
LIG_14-3-3_CanoR_1 185 189 PF00244 0.420
LIG_BRCT_BRCA1_1 113 117 PF00533 0.647
LIG_FHA_1 2 8 PF00498 0.665
LIG_FHA_2 121 127 PF00498 0.520
LIG_FHA_2 171 177 PF00498 0.585
LIG_FHA_2 76 82 PF00498 0.574
LIG_LIR_Apic_2 114 120 PF02991 0.615
LIG_LIR_Gen_1 164 174 PF02991 0.484
LIG_LIR_Nem_3 16 22 PF02991 0.559
LIG_LIR_Nem_3 164 170 PF02991 0.459
LIG_NRBOX 34 40 PF00104 0.588
LIG_SH2_PTP2 22 25 PF00017 0.578
LIG_SH2_STAT5 22 25 PF00017 0.578
LIG_SH3_1 22 28 PF00018 0.583
LIG_SH3_3 106 112 PF00018 0.576
LIG_SH3_3 22 28 PF00018 0.583
LIG_SH3_3 63 69 PF00018 0.617
LIG_SH3_4 57 64 PF00018 0.591
LIG_TRAF2_1 101 104 PF00917 0.645
LIG_TRAF2_1 173 176 PF00917 0.527
LIG_TRAF2_1 77 80 PF00917 0.523
MOD_CK1_1 194 200 PF00069 0.706
MOD_CK1_1 224 230 PF00069 0.793
MOD_CK1_1 234 240 PF00069 0.730
MOD_CK1_1 26 32 PF00069 0.574
MOD_CK1_1 260 266 PF00069 0.572
MOD_CK2_1 120 126 PF00069 0.528
MOD_CK2_1 170 176 PF00069 0.523
MOD_CK2_1 260 266 PF00069 0.618
MOD_CK2_1 75 81 PF00069 0.534
MOD_Cter_Amidation 73 76 PF01082 0.566
MOD_GlcNHglycan 186 189 PF01048 0.576
MOD_GlcNHglycan 196 199 PF01048 0.647
MOD_GlcNHglycan 223 226 PF01048 0.726
MOD_GlcNHglycan 233 236 PF01048 0.734
MOD_GSK3_1 210 217 PF00069 0.706
MOD_GSK3_1 219 226 PF00069 0.653
MOD_GSK3_1 23 30 PF00069 0.580
MOD_GSK3_1 245 252 PF00069 0.713
MOD_GSK3_1 257 264 PF00069 0.619
MOD_GSK3_1 273 280 PF00069 0.443
MOD_NEK2_1 1 6 PF00069 0.671
MOD_NEK2_1 170 175 PF00069 0.538
MOD_NEK2_1 184 189 PF00069 0.592
MOD_PIKK_1 210 216 PF00454 0.757
MOD_PKA_1 75 81 PF00069 0.533
MOD_PKA_2 170 176 PF00069 0.499
MOD_PKA_2 184 190 PF00069 0.471
MOD_PKA_2 210 216 PF00069 0.706
MOD_PKA_2 252 258 PF00069 0.752
MOD_PKA_2 75 81 PF00069 0.534
MOD_PKA_2 92 98 PF00069 0.551
MOD_Plk_1 1 7 PF00069 0.670
MOD_Plk_4 201 207 PF00069 0.561
MOD_Plk_4 277 283 PF00069 0.531
MOD_ProDKin_1 225 231 PF00069 0.738
MOD_ProDKin_1 234 240 PF00069 0.697
MOD_ProDKin_1 9 15 PF00069 0.595
MOD_SUMO_rev_2 255 263 PF00179 0.553
TRG_ER_diArg_1 151 154 PF00400 0.559
TRG_ER_diArg_1 41 43 PF00400 0.639
TRG_ER_diArg_1 66 68 PF00400 0.576
TRG_ER_diArg_1 75 77 PF00400 0.505

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMK6 Leptomonas seymouri 62% 98%
A0A1X0P771 Trypanosomatidae 35% 100%
A0A3S5H756 Leishmania donovani 99% 100%
A4HA08 Leishmania braziliensis 80% 100%
E9AS02 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QDH1 Leishmania major 92% 100%
V5DTM1 Trypanosoma cruzi 39% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS