RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HY49_LEIIN

TriTrypDb:

LINF_190007500

Length:

960

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HY49

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HY49

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	299	303	PF00656	0.656
CLV_C14_Caspase3-7	446	450	PF00656	0.819
CLV_C14_Caspase3-7	805	809	PF00656	0.552
CLV_NRD_NRD_1	15	17	PF00675	0.698
CLV_NRD_NRD_1	157	159	PF00675	0.721
CLV_NRD_NRD_1	423	425	PF00675	0.676
CLV_NRD_NRD_1	55	57	PF00675	0.748
CLV_NRD_NRD_1	729	731	PF00675	0.735
CLV_NRD_NRD_1	780	782	PF00675	0.589
CLV_NRD_NRD_1	895	897	PF00675	0.612

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PF30	Leptomonas seymouri	50%	98%
A0A3S7WVB1	Leishmania donovani	100%	100%
A4H9Y4	Leishmania braziliensis	79%	99%
E9ARX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QDJ4	Leishmania major	94%	100%

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