Putative chaperone protein DNAj

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

chaperone protein DNAj - putative

Species:

Leishmania infantum

UniProt:

A4HY36_LEIIN

TriTrypDb:

LINF_180022200

Length:

580

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HY36

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HY36

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	111	113	PF00675	0.518
CLV_NRD_NRD_1	192	194	PF00675	0.509
CLV_NRD_NRD_1	207	209	PF00675	0.258
CLV_NRD_NRD_1	62	64	PF00675	0.692
CLV_NRD_NRD_1	66	68	PF00675	0.658
CLV_PCSK_KEX2_1	111	113	PF00082	0.518
CLV_PCSK_KEX2_1	192	194	PF00082	0.509
CLV_PCSK_KEX2_1	207	209	PF00082	0.258
CLV_PCSK_KEX2_1	61	63	PF00082	0.703
CLV_PCSK_KEX2_1	66	68	PF00082	0.654
CLV_PCSK_PC7_1	62	68	PF00082	0.677
CLV_PCSK_SKI1_1	192	196	PF00082	0.441
CLV_PCSK_SKI1_1	207	211	PF00082	0.241
CLV_PCSK_SKI1_1	357	361	PF00082	0.436
CLV_PCSK_SKI1_1	471	475	PF00082	0.530
DEG_SCF_FBW7_1	487	494	PF00400	0.605
DEG_SPOP_SBC_1	302	306	PF00917	0.295
DEG_SPOP_SBC_1	491	495	PF00917	0.623
DOC_CKS1_1	335	340	PF01111	0.434
DOC_CYCLIN_RxL_1	279	289	PF00134	0.463
DOC_CYCLIN_RxL_1	518	528	PF00134	0.304
DOC_CYCLIN_yCln2_LP_2	16	22	PF00134	0.626
DOC_CYCLIN_yCln2_LP_2	383	389	PF00134	0.413
DOC_MAPK_gen_1	108	116	PF00069	0.504
DOC_MAPK_gen_1	207	214	PF00069	0.445
DOC_MAPK_gen_1	535	543	PF00069	0.333
DOC_MAPK_MEF2A_6	430	437	PF00069	0.368
DOC_MAPK_NFAT4_5	430	438	PF00069	0.367
DOC_PP2B_LxvP_1	523	526	PF13499	0.267
DOC_USP7_MATH_1	186	190	PF00917	0.349
DOC_USP7_MATH_1	244	248	PF00917	0.449
DOC_USP7_MATH_1	297	301	PF00917	0.396
DOC_USP7_MATH_1	37	41	PF00917	0.666
DOC_USP7_MATH_1	480	484	PF00917	0.531
DOC_USP7_MATH_1	97	101	PF00917	0.683
DOC_USP7_UBL2_3	496	500	PF12436	0.652
DOC_WW_Pin1_4	164	169	PF00397	0.426
DOC_WW_Pin1_4	224	229	PF00397	0.404
DOC_WW_Pin1_4	334	339	PF00397	0.424
DOC_WW_Pin1_4	487	492	PF00397	0.597
DOC_WW_Pin1_4	495	500	PF00397	0.717
DOC_WW_Pin1_4	95	100	PF00397	0.651
LIG_14-3-3_CanoR_1	156	162	PF00244	0.395
LIG_14-3-3_CanoR_1	211	219	PF00244	0.383
LIG_14-3-3_CanoR_1	282	287	PF00244	0.475
LIG_14-3-3_CanoR_1	301	311	PF00244	0.201
LIG_14-3-3_CanoR_1	419	424	PF00244	0.473
LIG_14-3-3_CanoR_1	430	434	PF00244	0.354
LIG_14-3-3_CanoR_1	446	452	PF00244	0.287
LIG_14-3-3_CanoR_1	513	517	PF00244	0.551
LIG_14-3-3_CanoR_1	549	558	PF00244	0.399
LIG_APCC_ABBA_1	226	231	PF00400	0.445
LIG_APCC_ABBAyCdc20_2	393	399	PF00400	0.434
LIG_BH_BH3_1	73	89	PF00452	0.513
LIG_BRCT_BRCA1_1	314	318	PF00533	0.365
LIG_Clathr_ClatBox_1	283	287	PF01394	0.359
LIG_FHA_1	11	17	PF00498	0.511
LIG_FHA_1	165	171	PF00498	0.440
LIG_FHA_1	189	195	PF00498	0.481
LIG_FHA_1	320	326	PF00498	0.546
LIG_FHA_1	378	384	PF00498	0.401
LIG_FHA_1	422	428	PF00498	0.428
LIG_FHA_1	446	452	PF00498	0.511
LIG_FHA_1	520	526	PF00498	0.399
LIG_FHA_2	303	309	PF00498	0.529
LIG_FHA_2	44	50	PF00498	0.603
LIG_FHA_2	492	498	PF00498	0.784
LIG_FHA_2	81	87	PF00498	0.632
LIG_LIR_Gen_1	151	162	PF02991	0.357
LIG_LIR_Gen_1	246	254	PF02991	0.465
LIG_LIR_Gen_1	315	325	PF02991	0.386
LIG_LIR_Gen_1	358	366	PF02991	0.490
LIG_LIR_Gen_1	409	416	PF02991	0.423
LIG_LIR_Gen_1	71	81	PF02991	0.572
LIG_LIR_Nem_3	151	157	PF02991	0.338
LIG_LIR_Nem_3	246	251	PF02991	0.381
LIG_LIR_Nem_3	315	321	PF02991	0.386
LIG_LIR_Nem_3	343	349	PF02991	0.489
LIG_LIR_Nem_3	358	363	PF02991	0.316
LIG_LIR_Nem_3	409	414	PF02991	0.424
LIG_LIR_Nem_3	517	523	PF02991	0.311
LIG_LIR_Nem_3	537	541	PF02991	0.144
LIG_LIR_Nem_3	562	568	PF02991	0.267
LIG_LIR_Nem_3	71	77	PF02991	0.466
LIG_NRBOX	326	332	PF00104	0.455
LIG_Pex14_1	314	318	PF04695	0.432
LIG_Rb_LxCxE_1	258	277	PF01857	0.274
LIG_SH2_CRK	248	252	PF00017	0.295
LIG_SH2_CRK	520	524	PF00017	0.283
LIG_SH2_CRK	538	542	PF00017	0.201
LIG_SH2_GRB2like	248	251	PF00017	0.452
LIG_SH2_NCK_1	147	151	PF00017	0.340
LIG_SH2_SRC	572	575	PF00017	0.333
LIG_SH2_STAP1	248	252	PF00017	0.404
LIG_SH2_STAP1	257	261	PF00017	0.411
LIG_SH2_STAP1	423	427	PF00017	0.425
LIG_SH2_STAP1	572	576	PF00017	0.267
LIG_SH2_STAT3	295	298	PF00017	0.405
LIG_SH2_STAT5	248	251	PF00017	0.498
LIG_SH2_STAT5	303	306	PF00017	0.301
LIG_SH2_STAT5	423	426	PF00017	0.462
LIG_SH3_3	383	389	PF00018	0.490
LIG_SUMO_SIM_anti_2	432	438	PF11976	0.391
LIG_SUMO_SIM_par_1	193	198	PF11976	0.507
LIG_SUMO_SIM_par_1	282	287	PF11976	0.360
LIG_TRAF2_1	571	574	PF00917	0.389
LIG_TYR_ITIM	518	523	PF00017	0.399
MOD_CDC14_SPxK_1	227	230	PF00782	0.421
MOD_CDK_SPK_2	495	500	PF00069	0.651
MOD_CDK_SPxK_1	224	230	PF00069	0.409
MOD_CDK_SPxxK_3	334	341	PF00069	0.430
MOD_CDK_SPxxK_3	495	502	PF00069	0.606
MOD_CK1_1	320	326	PF00069	0.468
MOD_CK1_1	495	501	PF00069	0.720
MOD_CK1_1	512	518	PF00069	0.406
MOD_CK2_1	112	118	PF00069	0.480
MOD_CK2_1	302	308	PF00069	0.542
MOD_CK2_1	419	425	PF00069	0.434
MOD_CK2_1	491	497	PF00069	0.758
MOD_GlcNHglycan	158	161	PF01048	0.455
MOD_GlcNHglycan	204	207	PF01048	0.504
MOD_GlcNHglycan	527	530	PF01048	0.353
MOD_GlcNHglycan	551	554	PF01048	0.345
MOD_GlcNHglycan	577	580	PF01048	0.486
MOD_GSK3_1	282	289	PF00069	0.307
MOD_GSK3_1	297	304	PF00069	0.250
MOD_GSK3_1	39	46	PF00069	0.711
MOD_GSK3_1	421	428	PF00069	0.512
MOD_GSK3_1	486	493	PF00069	0.684
MOD_GSK3_1	521	528	PF00069	0.453
MOD_GSK3_1	557	564	PF00069	0.329
MOD_LATS_1	519	525	PF00433	0.333
MOD_N-GLC_2	185	187	PF02516	0.297
MOD_NEK2_1	155	160	PF00069	0.533
MOD_NEK2_1	286	291	PF00069	0.494
MOD_NEK2_1	414	419	PF00069	0.415
MOD_NEK2_1	429	434	PF00069	0.308
MOD_NEK2_1	50	55	PF00069	0.561
MOD_NEK2_2	314	319	PF00069	0.437
MOD_NEK2_2	561	566	PF00069	0.333
MOD_PIKK_1	10	16	PF00454	0.652
MOD_PIKK_1	212	218	PF00454	0.394
MOD_PIKK_1	37	43	PF00454	0.698
MOD_PIKK_1	377	383	PF00454	0.536
MOD_PK_1	112	118	PF00069	0.368
MOD_PKA_1	207	213	PF00069	0.278
MOD_PKA_2	155	161	PF00069	0.390
MOD_PKA_2	207	213	PF00069	0.410
MOD_PKA_2	429	435	PF00069	0.440
MOD_PKA_2	445	451	PF00069	0.245
MOD_PKA_2	512	518	PF00069	0.473
MOD_PKB_1	299	307	PF00069	0.304
MOD_Plk_1	112	118	PF00069	0.480
MOD_Plk_1	425	431	PF00069	0.430
MOD_Plk_1	454	460	PF00069	0.376
MOD_Plk_1	561	567	PF00069	0.333
MOD_Plk_4	320	326	PF00069	0.384
MOD_Plk_4	374	380	PF00069	0.467
MOD_Plk_4	406	412	PF00069	0.535
MOD_Plk_4	429	435	PF00069	0.299
MOD_ProDKin_1	164	170	PF00069	0.417
MOD_ProDKin_1	224	230	PF00069	0.409
MOD_ProDKin_1	334	340	PF00069	0.425
MOD_ProDKin_1	487	493	PF00069	0.600
MOD_ProDKin_1	495	501	PF00069	0.713
MOD_ProDKin_1	95	101	PF00069	0.652
MOD_SUMO_rev_2	528	537	PF00179	0.330
TRG_AP2beta_CARGO_1	358	367	PF09066	0.326
TRG_DiLeu_BaEn_1	456	461	PF01217	0.413
TRG_DiLeu_BaEn_1	64	69	PF01217	0.594
TRG_DiLeu_BaEn_2	373	379	PF01217	0.389
TRG_DiLeu_BaLyEn_6	279	284	PF01217	0.442
TRG_ENDOCYTIC_2	248	251	PF00928	0.369
TRG_ENDOCYTIC_2	411	414	PF00928	0.319
TRG_ENDOCYTIC_2	520	523	PF00928	0.267
TRG_ENDOCYTIC_2	538	541	PF00928	0.267
TRG_ENDOCYTIC_2	572	575	PF00928	0.267
TRG_ER_diArg_1	192	194	PF00400	0.521
TRG_ER_diArg_1	207	209	PF00400	0.285
TRG_ER_diArg_1	60	63	PF00400	0.633
TRG_ER_diArg_1	65	67	PF00400	0.555
TRG_Pf-PMV_PEXEL_1	112	117	PF00026	0.475
TRG_Pf-PMV_PEXEL_1	193	198	PF00026	0.507
TRG_Pf-PMV_PEXEL_1	282	287	PF00026	0.465
TRG_Pf-PMV_PEXEL_1	402	406	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	66	70	PF00026	0.566

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HST8	Leptomonas seymouri	46%	99%
A0A1X0P804	Trypanosomatidae	27%	97%
A0A3Q8IB64	Leishmania donovani	99%	100%
A0A3R7KJ25	Trypanosoma rangeli	27%	94%
D0A549	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9ARV0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QDM3	Leishmania major	92%	100%
V5B4A5	Trypanosoma cruzi	27%	100%