Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HY11_LEIIN

TriTrypDb:

LINF_180019500

Length:

956

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HY11

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HY11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	55	59	PF00656	0.511
CLV_C14_Caspase3-7	565	569	PF00656	0.611
CLV_C14_Caspase3-7	666	670	PF00656	0.518
CLV_NRD_NRD_1	151	153	PF00675	0.620
CLV_NRD_NRD_1	27	29	PF00675	0.514
CLV_NRD_NRD_1	360	362	PF00675	0.594
CLV_NRD_NRD_1	407	409	PF00675	0.648
CLV_NRD_NRD_1	559	561	PF00675	0.605
CLV_NRD_NRD_1	621	623	PF00675	0.498
CLV_NRD_NRD_1	727	729	PF00675	0.590
CLV_PCSK_KEX2_1	407	409	PF00082	0.648
CLV_PCSK_KEX2_1	523	525	PF00082	0.564
CLV_PCSK_KEX2_1	561	563	PF00082	0.592
CLV_PCSK_KEX2_1	601	603	PF00082	0.551
CLV_PCSK_KEX2_1	621	623	PF00082	0.418
CLV_PCSK_KEX2_1	727	729	PF00082	0.590
CLV_PCSK_KEX2_1	733	735	PF00082	0.560
CLV_PCSK_KEX2_1	745	747	PF00082	0.518
CLV_PCSK_KEX2_1	953	955	PF00082	0.531
CLV_PCSK_PC1ET2_1	523	525	PF00082	0.627
CLV_PCSK_PC1ET2_1	561	563	PF00082	0.591
CLV_PCSK_PC1ET2_1	601	603	PF00082	0.551
CLV_PCSK_PC1ET2_1	727	729	PF00082	0.590
CLV_PCSK_PC1ET2_1	733	735	PF00082	0.560
CLV_PCSK_PC1ET2_1	745	747	PF00082	0.518
CLV_PCSK_PC7_1	403	409	PF00082	0.614
CLV_PCSK_PC7_1	519	525	PF00082	0.545
CLV_PCSK_SKI1_1	105	109	PF00082	0.598
CLV_PCSK_SKI1_1	28	32	PF00082	0.489
CLV_PCSK_SKI1_1	35	39	PF00082	0.493
CLV_PCSK_SKI1_1	51	55	PF00082	0.390
CLV_PCSK_SKI1_1	733	737	PF00082	0.632
CLV_PCSK_SKI1_1	752	756	PF00082	0.566
DEG_SCF_FBW7_2	214	221	PF00400	0.641
DOC_CKS1_1	873	878	PF01111	0.714
DOC_CYCLIN_yCln2_LP_2	923	926	PF00134	0.519
DOC_MAPK_gen_1	751	759	PF00069	0.511
DOC_MAPK_MEF2A_6	46	54	PF00069	0.458
DOC_PP1_RVXF_1	49	55	PF00149	0.458
DOC_PP2B_LxvP_1	585	588	PF13499	0.635
DOC_PP2B_LxvP_1	923	926	PF13499	0.519
DOC_PP4_FxxP_1	414	417	PF00568	0.554
DOC_PP4_MxPP_1	650	653	PF00568	0.514
DOC_USP7_MATH_1	106	110	PF00917	0.762
DOC_USP7_MATH_1	127	131	PF00917	0.607
DOC_USP7_MATH_1	164	168	PF00917	0.625
DOC_USP7_MATH_1	325	329	PF00917	0.597
DOC_USP7_MATH_1	435	439	PF00917	0.584
DOC_USP7_MATH_1	537	541	PF00917	0.646
DOC_USP7_MATH_1	564	568	PF00917	0.596
DOC_USP7_MATH_1	6	10	PF00917	0.518
DOC_USP7_MATH_1	625	629	PF00917	0.627
DOC_USP7_MATH_1	685	689	PF00917	0.577
DOC_USP7_MATH_1	716	720	PF00917	0.573
DOC_USP7_MATH_1	813	817	PF00917	0.600
DOC_USP7_MATH_1	82	86	PF00917	0.653
DOC_USP7_MATH_1	826	830	PF00917	0.530
DOC_USP7_MATH_1	861	865	PF00917	0.590
DOC_USP7_MATH_1	868	872	PF00917	0.576
DOC_USP7_MATH_1	897	901	PF00917	0.647
DOC_USP7_MATH_1	927	931	PF00917	0.597
DOC_USP7_UBL2_3	729	733	PF12436	0.588
DOC_WW_Pin1_4	168	173	PF00397	0.579
DOC_WW_Pin1_4	214	219	PF00397	0.640
DOC_WW_Pin1_4	271	276	PF00397	0.593
DOC_WW_Pin1_4	286	291	PF00397	0.604
DOC_WW_Pin1_4	305	310	PF00397	0.785
DOC_WW_Pin1_4	318	323	PF00397	0.560
DOC_WW_Pin1_4	336	341	PF00397	0.506
DOC_WW_Pin1_4	378	383	PF00397	0.526
DOC_WW_Pin1_4	39	44	PF00397	0.523
DOC_WW_Pin1_4	431	436	PF00397	0.578
DOC_WW_Pin1_4	437	442	PF00397	0.577
DOC_WW_Pin1_4	484	489	PF00397	0.589
DOC_WW_Pin1_4	500	505	PF00397	0.605
DOC_WW_Pin1_4	507	512	PF00397	0.580
DOC_WW_Pin1_4	546	551	PF00397	0.617
DOC_WW_Pin1_4	568	573	PF00397	0.773
DOC_WW_Pin1_4	579	584	PF00397	0.570
DOC_WW_Pin1_4	595	600	PF00397	0.574
DOC_WW_Pin1_4	664	669	PF00397	0.734
DOC_WW_Pin1_4	70	75	PF00397	0.575
DOC_WW_Pin1_4	757	762	PF00397	0.723
DOC_WW_Pin1_4	766	771	PF00397	0.543
DOC_WW_Pin1_4	815	820	PF00397	0.587
DOC_WW_Pin1_4	872	877	PF00397	0.597
LIG_14-3-3_CanoR_1	24	30	PF00244	0.471
LIG_14-3-3_CanoR_1	361	365	PF00244	0.599
LIG_14-3-3_CanoR_1	410	415	PF00244	0.631
LIG_14-3-3_CanoR_1	542	550	PF00244	0.615
LIG_14-3-3_CanoR_1	624	630	PF00244	0.637
LIG_14-3-3_CanoR_1	637	645	PF00244	0.479
LIG_14-3-3_CanoR_1	662	668	PF00244	0.580
LIG_14-3-3_CanoR_1	693	701	PF00244	0.505
LIG_14-3-3_CanoR_1	801	810	PF00244	0.554
LIG_14-3-3_CanoR_1	824	832	PF00244	0.605
LIG_14-3-3_CanoR_1	843	848	PF00244	0.594
LIG_14-3-3_CanoR_1	874	883	PF00244	0.583
LIG_14-3-3_CanoR_1	934	942	PF00244	0.496
LIG_APCC_ABBA_1	50	55	PF00400	0.503
LIG_BRCT_BRCA1_1	877	881	PF00533	0.633
LIG_CtBP_PxDLS_1	441	445	PF00389	0.592
LIG_FHA_1	110	116	PF00498	0.618
LIG_FHA_1	229	235	PF00498	0.575
LIG_FHA_1	378	384	PF00498	0.621
LIG_FHA_1	40	46	PF00498	0.514
LIG_FHA_1	580	586	PF00498	0.602
LIG_FHA_1	629	635	PF00498	0.535
LIG_FHA_1	794	800	PF00498	0.588
LIG_FHA_1	806	812	PF00498	0.536
LIG_FHA_2	29	35	PF00498	0.530
LIG_FHA_2	347	353	PF00498	0.654
LIG_FHA_2	411	417	PF00498	0.558
LIG_LIR_Apic_2	369	375	PF02991	0.538
LIG_LIR_Apic_2	411	417	PF02991	0.558
LIG_LIR_Apic_2	436	442	PF02991	0.557
LIG_LIR_Apic_2	742	747	PF02991	0.525
LIG_LIR_Gen_1	455	465	PF02991	0.529
LIG_LIR_Gen_1	773	783	PF02991	0.497
LIG_LIR_Gen_1	842	853	PF02991	0.591
LIG_LIR_Gen_1	930	940	PF02991	0.558
LIG_LIR_Nem_3	422	428	PF02991	0.563
LIG_LIR_Nem_3	455	460	PF02991	0.581
LIG_LIR_Nem_3	773	778	PF02991	0.505
LIG_LIR_Nem_3	930	935	PF02991	0.588
LIG_LIR_Nem_3	936	942	PF02991	0.493
LIG_MYND_1	583	587	PF01753	0.605
LIG_NRP_CendR_1	953	956	PF00754	0.527
LIG_RPA_C_Fungi	897	909	PF08784	0.521
LIG_SH2_CRK	372	376	PF00017	0.579
LIG_SH2_CRK	391	395	PF00017	0.541
LIG_SH2_CRK	775	779	PF00017	0.567
LIG_SH2_GRB2like	372	375	PF00017	0.593
LIG_SH2_NCK_1	372	376	PF00017	0.579
LIG_SH2_SRC	372	375	PF00017	0.593
LIG_SH2_STAP1	943	947	PF00017	0.524
LIG_SH2_STAT3	806	809	PF00017	0.606
LIG_SH2_STAT5	25	28	PF00017	0.506
LIG_SH2_STAT5	613	616	PF00017	0.510
LIG_SH2_STAT5	65	68	PF00017	0.556
LIG_SH3_1	319	325	PF00018	0.559
LIG_SH3_2	485	490	PF14604	0.571
LIG_SH3_2	588	593	PF14604	0.599
LIG_SH3_2	819	824	PF14604	0.605
LIG_SH3_3	148	154	PF00018	0.582
LIG_SH3_3	224	230	PF00018	0.596
LIG_SH3_3	247	253	PF00018	0.603
LIG_SH3_3	309	315	PF00018	0.690
LIG_SH3_3	319	325	PF00018	0.572
LIG_SH3_3	337	343	PF00018	0.576
LIG_SH3_3	380	386	PF00018	0.590
LIG_SH3_3	464	470	PF00018	0.565
LIG_SH3_3	482	488	PF00018	0.508
LIG_SH3_3	508	514	PF00018	0.643
LIG_SH3_3	547	553	PF00018	0.611
LIG_SH3_3	572	578	PF00018	0.621
LIG_SH3_3	584	590	PF00018	0.578
LIG_SH3_3	764	770	PF00018	0.574
LIG_SH3_3	816	822	PF00018	0.606
LIG_SH3_3	888	894	PF00018	0.780
LIG_SH3_3	9	15	PF00018	0.544
LIG_SH3_CIN85_PxpxPR_1	382	387	PF14604	0.592
LIG_SUMO_SIM_par_1	194	200	PF11976	0.571
LIG_SUMO_SIM_par_1	230	236	PF11976	0.555
LIG_SUMO_SIM_par_1	854	860	PF11976	0.583
LIG_TRAF2_1	219	222	PF00917	0.568
LIG_TRAF2_1	31	34	PF00917	0.517
LIG_TYR_ITIM	423	428	PF00017	0.563
LIG_TYR_ITSM	771	778	PF00017	0.514
LIG_UBA3_1	254	262	PF00899	0.576
MOD_CDC14_SPxK_1	487	490	PF00782	0.590
MOD_CDC14_SPxK_1	598	601	PF00782	0.668
MOD_CDC14_SPxK_1	818	821	PF00782	0.591
MOD_CDK_SPK_2	507	512	PF00069	0.590
MOD_CDK_SPK_2	546	551	PF00069	0.637
MOD_CDK_SPK_2	70	75	PF00069	0.575
MOD_CDK_SPK_2	766	771	PF00069	0.562
MOD_CDK_SPK_2	872	877	PF00069	0.587
MOD_CDK_SPxK_1	214	220	PF00069	0.641
MOD_CDK_SPxK_1	484	490	PF00069	0.571
MOD_CDK_SPxK_1	595	601	PF00069	0.678
MOD_CDK_SPxK_1	815	821	PF00069	0.590
MOD_CDK_SPxxK_3	168	175	PF00069	0.581
MOD_CDK_SPxxK_3	39	46	PF00069	0.515
MOD_CDK_SPxxK_3	595	602	PF00069	0.581
MOD_CK1_1	10	16	PF00069	0.555
MOD_CK1_1	109	115	PF00069	0.573
MOD_CK1_1	139	145	PF00069	0.564
MOD_CK1_1	165	171	PF00069	0.614
MOD_CK1_1	17	23	PF00069	0.445
MOD_CK1_1	188	194	PF00069	0.556
MOD_CK1_1	199	205	PF00069	0.563
MOD_CK1_1	268	274	PF00069	0.703
MOD_CK1_1	345	351	PF00069	0.621
MOD_CK1_1	397	403	PF00069	0.593
MOD_CK1_1	433	439	PF00069	0.569
MOD_CK1_1	628	634	PF00069	0.602
MOD_CK1_1	675	681	PF00069	0.612
MOD_CK1_1	70	76	PF00069	0.634
MOD_CK1_1	709	715	PF00069	0.580
MOD_CK1_1	793	799	PF00069	0.583
MOD_CK1_1	87	93	PF00069	0.535
MOD_CK2_1	28	34	PF00069	0.483
MOD_CK2_1	346	352	PF00069	0.655
MOD_CK2_1	410	416	PF00069	0.564
MOD_CK2_1	645	651	PF00069	0.572
MOD_CK2_1	901	907	PF00069	0.560
MOD_CK2_1	927	933	PF00069	0.527
MOD_GlcNHglycan	129	132	PF01048	0.593
MOD_GlcNHglycan	138	141	PF01048	0.529
MOD_GlcNHglycan	164	167	PF01048	0.654
MOD_GlcNHglycan	187	190	PF01048	0.623
MOD_GlcNHglycan	204	208	PF01048	0.506
MOD_GlcNHglycan	270	273	PF01048	0.648
MOD_GlcNHglycan	275	278	PF01048	0.600
MOD_GlcNHglycan	446	449	PF01048	0.667
MOD_GlcNHglycan	505	508	PF01048	0.656
MOD_GlcNHglycan	527	530	PF01048	0.624
MOD_GlcNHglycan	579	582	PF01048	0.695
MOD_GlcNHglycan	638	641	PF01048	0.588
MOD_GlcNHglycan	645	648	PF01048	0.558
MOD_GlcNHglycan	669	672	PF01048	0.586
MOD_GlcNHglycan	69	72	PF01048	0.548
MOD_GlcNHglycan	696	699	PF01048	0.654
MOD_GlcNHglycan	708	711	PF01048	0.532
MOD_GlcNHglycan	792	795	PF01048	0.620
MOD_GlcNHglycan	80	83	PF01048	0.635
MOD_GlcNHglycan	815	818	PF01048	0.613
MOD_GlcNHglycan	826	829	PF01048	0.572
MOD_GlcNHglycan	833	836	PF01048	0.547
MOD_GlcNHglycan	86	89	PF01048	0.699
MOD_GlcNHglycan	863	866	PF01048	0.574
MOD_GlcNHglycan	877	880	PF01048	0.538
MOD_GlcNHglycan	899	902	PF01048	0.620
MOD_GlcNHglycan	903	906	PF01048	0.503
MOD_GSK3_1	164	171	PF00069	0.619
MOD_GSK3_1	196	203	PF00069	0.577
MOD_GSK3_1	263	270	PF00069	0.612
MOD_GSK3_1	286	293	PF00069	0.734
MOD_GSK3_1	294	301	PF00069	0.588
MOD_GSK3_1	325	332	PF00069	0.615
MOD_GSK3_1	342	349	PF00069	0.548
MOD_GSK3_1	373	380	PF00069	0.579
MOD_GSK3_1	4	11	PF00069	0.585
MOD_GSK3_1	431	438	PF00069	0.594
MOD_GSK3_1	440	447	PF00069	0.641
MOD_GSK3_1	448	455	PF00069	0.470
MOD_GSK3_1	499	506	PF00069	0.611
MOD_GSK3_1	564	571	PF00069	0.625
MOD_GSK3_1	579	586	PF00069	0.527
MOD_GSK3_1	628	635	PF00069	0.574
MOD_GSK3_1	660	667	PF00069	0.585
MOD_GSK3_1	671	678	PF00069	0.586
MOD_GSK3_1	705	712	PF00069	0.571
MOD_GSK3_1	73	80	PF00069	0.608
MOD_GSK3_1	736	743	PF00069	0.566
MOD_GSK3_1	766	773	PF00069	0.512
MOD_GSK3_1	801	808	PF00069	0.532
MOD_GSK3_1	813	820	PF00069	0.591
MOD_GSK3_1	822	829	PF00069	0.590
MOD_GSK3_1	84	91	PF00069	0.650
MOD_GSK3_1	857	864	PF00069	0.628
MOD_GSK3_1	868	875	PF00069	0.536
MOD_GSK3_1	897	904	PF00069	0.559
MOD_LATS_1	406	412	PF00433	0.620
MOD_N-GLC_1	268	273	PF02516	0.586
MOD_N-GLC_1	293	298	PF02516	0.614
MOD_N-GLC_1	430	435	PF02516	0.551
MOD_N-GLC_1	537	542	PF02516	0.615
MOD_NEK2_1	101	106	PF00069	0.568
MOD_NEK2_1	136	141	PF00069	0.600
MOD_NEK2_1	180	185	PF00069	0.596
MOD_NEK2_1	292	297	PF00069	0.645
MOD_NEK2_1	394	399	PF00069	0.622
MOD_NEK2_1	444	449	PF00069	0.691
MOD_NEK2_1	530	535	PF00069	0.603
MOD_NEK2_1	612	617	PF00069	0.521
MOD_NEK2_1	660	665	PF00069	0.580
MOD_NEK2_1	67	72	PF00069	0.565
MOD_NEK2_1	672	677	PF00069	0.568
MOD_NEK2_1	694	699	PF00069	0.525
MOD_NEK2_1	949	954	PF00069	0.545
MOD_NEK2_2	230	235	PF00069	0.577
MOD_NEK2_2	828	833	PF00069	0.602
MOD_NEK2_2	927	932	PF00069	0.526
MOD_PIKK_1	543	549	PF00454	0.697
MOD_PIKK_1	801	807	PF00454	0.530
MOD_PIKK_1	826	832	PF00454	0.604
MOD_PK_1	843	849	PF00069	0.506
MOD_PKA_1	28	34	PF00069	0.489
MOD_PKA_2	23	29	PF00069	0.448
MOD_PKA_2	284	290	PF00069	0.589
MOD_PKA_2	360	366	PF00069	0.595
MOD_PKA_2	409	415	PF00069	0.587
MOD_PKA_2	525	531	PF00069	0.577
MOD_PKA_2	636	642	PF00069	0.512
MOD_PKA_2	770	776	PF00069	0.618
MOD_PKA_2	82	88	PF00069	0.611
MOD_PKA_2	901	907	PF00069	0.576
MOD_PKA_2	933	939	PF00069	0.629
MOD_PKB_1	408	416	PF00069	0.602
MOD_Plk_1	7	13	PF00069	0.752
MOD_Plk_4	17	23	PF00069	0.475
MOD_Plk_4	191	197	PF00069	0.567
MOD_Plk_4	307	313	PF00069	0.649
MOD_Plk_4	793	799	PF00069	0.583
MOD_Plk_4	843	849	PF00069	0.593
MOD_Plk_4	927	933	PF00069	0.527
MOD_ProDKin_1	168	174	PF00069	0.578
MOD_ProDKin_1	214	220	PF00069	0.641
MOD_ProDKin_1	271	277	PF00069	0.592
MOD_ProDKin_1	286	292	PF00069	0.607
MOD_ProDKin_1	305	311	PF00069	0.778
MOD_ProDKin_1	318	324	PF00069	0.561
MOD_ProDKin_1	336	342	PF00069	0.507
MOD_ProDKin_1	378	384	PF00069	0.524
MOD_ProDKin_1	39	45	PF00069	0.518
MOD_ProDKin_1	431	437	PF00069	0.578
MOD_ProDKin_1	484	490	PF00069	0.591
MOD_ProDKin_1	500	506	PF00069	0.605
MOD_ProDKin_1	507	513	PF00069	0.581
MOD_ProDKin_1	546	552	PF00069	0.615
MOD_ProDKin_1	568	574	PF00069	0.774
MOD_ProDKin_1	579	585	PF00069	0.572
MOD_ProDKin_1	595	601	PF00069	0.570
MOD_ProDKin_1	664	670	PF00069	0.732
MOD_ProDKin_1	70	76	PF00069	0.579
MOD_ProDKin_1	757	763	PF00069	0.724
MOD_ProDKin_1	766	772	PF00069	0.543
MOD_ProDKin_1	815	821	PF00069	0.590
MOD_ProDKin_1	872	878	PF00069	0.597
TRG_DiLeu_BaEn_1	32	37	PF01217	0.458
TRG_DiLeu_BaEn_3	32	38	PF01217	0.439
TRG_DiLeu_BaEn_4	33	39	PF01217	0.475
TRG_DiLeu_BaLyEn_6	250	255	PF01217	0.559
TRG_DiLeu_LyEn_5	32	37	PF01217	0.458
TRG_ENDOCYTIC_2	391	394	PF00928	0.595
TRG_ENDOCYTIC_2	425	428	PF00928	0.571
TRG_ENDOCYTIC_2	775	778	PF00928	0.557
TRG_ENDOCYTIC_2	845	848	PF00928	0.591
TRG_ENDOCYTIC_2	939	942	PF00928	0.518
TRG_ER_diArg_1	182	185	PF00400	0.578
TRG_ER_diArg_1	234	237	PF00400	0.611
TRG_ER_diArg_1	620	622	PF00400	0.503
TRG_ER_diArg_1	953	956	PF00400	0.536
TRG_NLS_MonoCore_2	725	730	PF00514	0.578
TRG_NLS_MonoExtC_3	725	731	PF00514	0.578
TRG_NLS_MonoExtN_4	522	527	PF00514	0.563
TRG_NLS_MonoExtN_4	724	730	PF00514	0.567
TRG_Pf-PMV_PEXEL_1	28	32	PF00026	0.489
TRG_Pf-PMV_PEXEL_1	888	893	PF00026	0.591

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYQ7	Leptomonas seymouri	31%	82%
A0A3Q8IB34	Leishmania donovani	99%	100%
A4H9P4	Leishmania braziliensis	61%	100%
E9ARS5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4QDP8	Leishmania major	87%	100%