Chaperone/Protein Folding, Activator of Hsp90 ATPase, N-terminal
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | yes | yes: 2 |
Forrest at al. (procyclic) | yes | yes: 2 |
Silverman et al. | no | yes: 0 |
Pissara et al. | yes | yes: 12 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 11 |
NetGPI | no | yes: 0, no: 11 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005654 | nucleoplasm | 2 | 1 |
GO:0005737 | cytoplasm | 2 | 1 |
GO:0005829 | cytosol | 2 | 1 |
GO:0110165 | cellular anatomical entity | 1 | 1 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pescher et al. (upgregulation) | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4HXP7
Term | Name | Level | Count |
---|---|---|---|
GO:0006457 | protein folding | 2 | 1 |
GO:0009987 | cellular process | 1 | 1 |
GO:0032781 | positive regulation of ATP-dependent activity | 4 | 1 |
GO:0043462 | regulation of ATP-dependent activity | 3 | 1 |
GO:0044093 | positive regulation of molecular function | 3 | 1 |
GO:0065007 | biological regulation | 1 | 1 |
GO:0065009 | regulation of molecular function | 2 | 1 |
Term | Name | Level | Count |
---|---|---|---|
GO:0001671 | ATPase activator activity | 3 | 12 |
GO:0005488 | binding | 1 | 12 |
GO:0005515 | protein binding | 2 | 12 |
GO:0031072 | heat shock protein binding | 3 | 12 |
GO:0051087 | protein-folding chaperone binding | 3 | 12 |
GO:0051879 | Hsp90 protein binding | 4 | 12 |
GO:0098772 | molecular function regulator activity | 1 | 12 |
GO:0140677 | molecular function activator activity | 2 | 12 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_C14_Caspase3-7 | 129 | 133 | PF00656 | 0.458 |
CLV_C14_Caspase3-7 | 15 | 19 | PF00656 | 0.541 |
CLV_NRD_NRD_1 | 78 | 80 | PF00675 | 0.261 |
CLV_PCSK_SKI1_1 | 171 | 175 | PF00082 | 0.512 |
CLV_PCSK_SKI1_1 | 341 | 345 | PF00082 | 0.261 |
CLV_PCSK_SKI1_1 | 41 | 45 | PF00082 | 0.287 |
DOC_PP2B_LxvP_1 | 179 | 182 | PF13499 | 0.551 |
DOC_USP7_MATH_1 | 188 | 192 | PF00917 | 0.744 |
DOC_USP7_UBL2_3 | 90 | 94 | PF12436 | 0.456 |
DOC_WW_Pin1_4 | 190 | 195 | PF00397 | 0.674 |
DOC_WW_Pin1_4 | 247 | 252 | PF00397 | 0.547 |
LIG_14-3-3_CanoR_1 | 149 | 153 | PF00244 | 0.547 |
LIG_14-3-3_CanoR_1 | 249 | 255 | PF00244 | 0.485 |
LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.543 |
LIG_BRCT_BRCA1_1 | 217 | 221 | PF00533 | 0.519 |
LIG_CtBP_PxDLS_1 | 52 | 56 | PF00389 | 0.477 |
LIG_deltaCOP1_diTrp_1 | 330 | 337 | PF00928 | 0.461 |
LIG_EVH1_1 | 179 | 183 | PF00568 | 0.599 |
LIG_FHA_1 | 100 | 106 | PF00498 | 0.441 |
LIG_FHA_1 | 196 | 202 | PF00498 | 0.695 |
LIG_FHA_1 | 251 | 257 | PF00498 | 0.566 |
LIG_FHA_2 | 127 | 133 | PF00498 | 0.476 |
LIG_FHA_2 | 156 | 162 | PF00498 | 0.497 |
LIG_FHA_2 | 309 | 315 | PF00498 | 0.491 |
LIG_LIR_Gen_1 | 158 | 167 | PF02991 | 0.459 |
LIG_LIR_Gen_1 | 233 | 241 | PF02991 | 0.455 |
LIG_LIR_Gen_1 | 270 | 281 | PF02991 | 0.471 |
LIG_LIR_Gen_1 | 58 | 67 | PF02991 | 0.550 |
LIG_LIR_LC3C_4 | 297 | 300 | PF02991 | 0.483 |
LIG_LIR_Nem_3 | 158 | 163 | PF02991 | 0.467 |
LIG_LIR_Nem_3 | 233 | 238 | PF02991 | 0.445 |
LIG_LIR_Nem_3 | 270 | 276 | PF02991 | 0.471 |
LIG_LIR_Nem_3 | 58 | 64 | PF02991 | 0.550 |
LIG_Pex14_1 | 332 | 336 | PF04695 | 0.461 |
LIG_Pex14_2 | 160 | 164 | PF04695 | 0.461 |
LIG_SH2_CRK | 235 | 239 | PF00017 | 0.526 |
LIG_SH2_PTP2 | 273 | 276 | PF00017 | 0.522 |
LIG_SH2_SRC | 124 | 127 | PF00017 | 0.522 |
LIG_SH2_SRC | 167 | 170 | PF00017 | 0.430 |
LIG_SH2_SRC | 273 | 276 | PF00017 | 0.522 |
LIG_SH2_STAP1 | 124 | 128 | PF00017 | 0.473 |
LIG_SH2_STAP1 | 346 | 350 | PF00017 | 0.381 |
LIG_SH2_STAT5 | 247 | 250 | PF00017 | 0.461 |
LIG_SH2_STAT5 | 273 | 276 | PF00017 | 0.500 |
LIG_SH2_STAT5 | 61 | 64 | PF00017 | 0.538 |
LIG_SH2_STAT5 | 86 | 89 | PF00017 | 0.461 |
LIG_SH3_3 | 177 | 183 | PF00018 | 0.585 |
LIG_SUMO_SIM_anti_2 | 297 | 302 | PF11976 | 0.533 |
LIG_TRAF2_1 | 327 | 330 | PF00917 | 0.522 |
LIG_TYR_ITIM | 59 | 64 | PF00017 | 0.547 |
LIG_WRC_WIRS_1 | 156 | 161 | PF05994 | 0.497 |
MOD_CK1_1 | 14 | 20 | PF00069 | 0.655 |
MOD_CK1_1 | 186 | 192 | PF00069 | 0.752 |
MOD_CK1_1 | 193 | 199 | PF00069 | 0.700 |
MOD_CK1_1 | 209 | 215 | PF00069 | 0.522 |
MOD_CK1_1 | 242 | 248 | PF00069 | 0.482 |
MOD_CK1_1 | 250 | 256 | PF00069 | 0.459 |
MOD_CK1_1 | 33 | 39 | PF00069 | 0.547 |
MOD_CK1_1 | 68 | 74 | PF00069 | 0.467 |
MOD_CK2_1 | 211 | 217 | PF00069 | 0.705 |
MOD_CK2_1 | 308 | 314 | PF00069 | 0.477 |
MOD_CK2_1 | 324 | 330 | PF00069 | 0.473 |
MOD_Cter_Amidation | 201 | 204 | PF01082 | 0.618 |
MOD_GlcNHglycan | 174 | 177 | PF01048 | 0.673 |
MOD_GlcNHglycan | 186 | 189 | PF01048 | 0.677 |
MOD_GlcNHglycan | 269 | 272 | PF01048 | 0.310 |
MOD_GlcNHglycan | 317 | 320 | PF01048 | 0.335 |
MOD_GlcNHglycan | 69 | 73 | PF01048 | 0.261 |
MOD_GSK3_1 | 184 | 191 | PF00069 | 0.711 |
MOD_GSK3_1 | 202 | 209 | PF00069 | 0.654 |
MOD_GSK3_1 | 211 | 218 | PF00069 | 0.567 |
MOD_GSK3_1 | 309 | 316 | PF00069 | 0.563 |
MOD_GSK3_1 | 35 | 42 | PF00069 | 0.548 |
MOD_GSK3_1 | 68 | 75 | PF00069 | 0.465 |
MOD_LATS_1 | 37 | 43 | PF00433 | 0.558 |
MOD_N-GLC_1 | 215 | 220 | PF02516 | 0.576 |
MOD_NEK2_1 | 313 | 318 | PF00069 | 0.550 |
MOD_NEK2_1 | 89 | 94 | PF00069 | 0.475 |
MOD_NEK2_2 | 148 | 153 | PF00069 | 0.547 |
MOD_PIKK_1 | 134 | 140 | PF00454 | 0.470 |
MOD_PIKK_1 | 30 | 36 | PF00454 | 0.547 |
MOD_PIKK_1 | 313 | 319 | PF00454 | 0.566 |
MOD_PK_1 | 39 | 45 | PF00069 | 0.566 |
MOD_PKA_1 | 203 | 209 | PF00069 | 0.740 |
MOD_PKA_2 | 148 | 154 | PF00069 | 0.545 |
MOD_Plk_1 | 216 | 222 | PF00069 | 0.514 |
MOD_Plk_1 | 72 | 78 | PF00069 | 0.453 |
MOD_Plk_2-3 | 155 | 161 | PF00069 | 0.537 |
MOD_Plk_2-3 | 324 | 330 | PF00069 | 0.539 |
MOD_Plk_4 | 139 | 145 | PF00069 | 0.547 |
MOD_Plk_4 | 155 | 161 | PF00069 | 0.547 |
MOD_Plk_4 | 242 | 248 | PF00069 | 0.478 |
MOD_Plk_4 | 277 | 283 | PF00069 | 0.514 |
MOD_Plk_4 | 294 | 300 | PF00069 | 0.379 |
MOD_Plk_4 | 39 | 45 | PF00069 | 0.556 |
MOD_ProDKin_1 | 190 | 196 | PF00069 | 0.670 |
MOD_ProDKin_1 | 247 | 253 | PF00069 | 0.547 |
MOD_SUMO_for_1 | 304 | 307 | PF00179 | 0.488 |
MOD_SUMO_for_1 | 62 | 65 | PF00179 | 0.547 |
MOD_SUMO_rev_2 | 250 | 258 | PF00179 | 0.547 |
TRG_ENDOCYTIC_2 | 235 | 238 | PF00928 | 0.537 |
TRG_ENDOCYTIC_2 | 273 | 276 | PF00928 | 0.522 |
TRG_ENDOCYTIC_2 | 61 | 64 | PF00928 | 0.547 |
TRG_ENDOCYTIC_2 | 86 | 89 | PF00928 | 0.461 |
TRG_NES_CRM1_1 | 53 | 66 | PF08389 | 0.520 |
TRG_Pf-PMV_PEXEL_1 | 30 | 34 | PF00026 | 0.273 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N1I2A4 | Leptomonas seymouri | 71% | 99% |
A0A0S4JAT2 | Bodo saltans | 48% | 100% |
A0A1X0P6W4 | Trypanosomatidae | 58% | 100% |
A0A3R7MY48 | Trypanosoma rangeli | 54% | 100% |
A0A3S7WUS5 | Leishmania donovani | 99% | 100% |
A4H9C6 | Leishmania braziliensis | 84% | 100% |
A6QQC0 | Bos taurus | 27% | 100% |
D0A023 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 58% | 100% |
E9ARF8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 92% | 100% |
O95433 | Homo sapiens | 31% | 100% |
Q12449 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 24% | 100% |
Q4QE21 | Leishmania major | 96% | 100% |
Q8BK64 | Mus musculus | 30% | 100% |
Q8N9S3 | Mus musculus | 28% | 100% |
Q9P782 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 25% | 100% |
V5B6E4 | Trypanosoma cruzi | 58% | 100% |