LeishMANIAdb
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Putative 5'-3' exonuclease

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 5'-3' exonuclease
Gene product:
5'-3' exoribonuclease B - putative
Species:
Leishmania infantum
UniProt:
A4HXJ2_LEIIN
TriTrypDb:
LINF_170018800
Length:
1158

Annotations

Annotations by Jardim et al.

Nucleases, 5'-3' exonuclease

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 8
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 8

Expansion

Sequence features

A4HXJ2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HXJ2

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 11
GO:0006725 cellular aromatic compound metabolic process 3 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0008152 metabolic process 1 11
GO:0009987 cellular process 1 11
GO:0016070 RNA metabolic process 5 11
GO:0034641 cellular nitrogen compound metabolic process 3 11
GO:0043170 macromolecule metabolic process 3 11
GO:0044237 cellular metabolic process 2 11
GO:0044238 primary metabolic process 2 11
GO:0046483 heterocycle metabolic process 3 11
GO:0071704 organic substance metabolic process 2 11
GO:0090304 nucleic acid metabolic process 4 11
GO:1901360 organic cyclic compound metabolic process 3 11
GO:0000956 nuclear-transcribed mRNA catabolic process 7 1
GO:0006401 RNA catabolic process 5 1
GO:0006402 mRNA catabolic process 6 1
GO:0009056 catabolic process 2 1
GO:0009057 macromolecule catabolic process 4 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0010468 regulation of gene expression 5 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0010629 negative regulation of gene expression 6 1
GO:0016071 mRNA metabolic process 6 1
GO:0019222 regulation of metabolic process 3 1
GO:0019439 aromatic compound catabolic process 4 1
GO:0034655 nucleobase-containing compound catabolic process 4 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0044270 cellular nitrogen compound catabolic process 4 1
GO:0046700 heterocycle catabolic process 4 1
GO:0048519 negative regulation of biological process 3 1
GO:0050789 regulation of biological process 2 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:1901361 organic cyclic compound catabolic process 4 1
GO:1901575 organic substance catabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 11
GO:0003824 catalytic activity 1 11
GO:0004518 nuclease activity 4 11
GO:0004527 exonuclease activity 5 11
GO:0005488 binding 1 11
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0043167 ion binding 2 11
GO:0043169 cation binding 3 11
GO:0046872 metal ion binding 4 11
GO:0097159 organic cyclic compound binding 2 11
GO:1901363 heterocyclic compound binding 2 11
GO:0003723 RNA binding 4 1
GO:0004532 RNA exonuclease activity 5 1
GO:0004534 5'-3' RNA exonuclease activity 7 1
GO:0004540 RNA nuclease activity 4 1
GO:0008409 5'-3' exonuclease activity 6 1
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 1
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 1
GO:0140098 catalytic activity, acting on RNA 3 1
GO:0140640 catalytic activity, acting on a nucleic acid 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 490 494 PF00656 0.614
CLV_C14_Caspase3-7 852 856 PF00656 0.781
CLV_NRD_NRD_1 11 13 PF00675 0.338
CLV_NRD_NRD_1 1113 1115 PF00675 0.322
CLV_NRD_NRD_1 369 371 PF00675 0.540
CLV_NRD_NRD_1 372 374 PF00675 0.564
CLV_NRD_NRD_1 536 538 PF00675 0.478
CLV_NRD_NRD_1 661 663 PF00675 0.348
CLV_NRD_NRD_1 888 890 PF00675 0.647
CLV_NRD_NRD_1 97 99 PF00675 0.268
CLV_NRD_NRD_1 975 977 PF00675 0.477
CLV_NRD_NRD_1 986 988 PF00675 0.482
CLV_NRD_NRD_1 996 998 PF00675 0.574
CLV_PCSK_FUR_1 1111 1115 PF00082 0.339
CLV_PCSK_FUR_1 370 374 PF00082 0.555
CLV_PCSK_FUR_1 95 99 PF00082 0.246
CLV_PCSK_FUR_1 984 988 PF00082 0.491
CLV_PCSK_KEX2_1 1113 1115 PF00082 0.308
CLV_PCSK_KEX2_1 340 342 PF00082 0.448
CLV_PCSK_KEX2_1 369 371 PF00082 0.522
CLV_PCSK_KEX2_1 372 374 PF00082 0.550
CLV_PCSK_KEX2_1 535 537 PF00082 0.480
CLV_PCSK_KEX2_1 661 663 PF00082 0.383
CLV_PCSK_KEX2_1 888 890 PF00082 0.620
CLV_PCSK_KEX2_1 97 99 PF00082 0.269
CLV_PCSK_KEX2_1 975 977 PF00082 0.477
CLV_PCSK_KEX2_1 984 986 PF00082 0.502
CLV_PCSK_PC1ET2_1 340 342 PF00082 0.420
CLV_PCSK_PC1ET2_1 535 537 PF00082 0.461
CLV_PCSK_SKI1_1 130 134 PF00082 0.250
CLV_PCSK_SKI1_1 537 541 PF00082 0.574
CLV_PCSK_SKI1_1 600 604 PF00082 0.339
CLV_PCSK_SKI1_1 832 836 PF00082 0.286
DEG_SPOP_SBC_1 376 380 PF00917 0.695
DEG_SPOP_SBC_1 553 557 PF00917 0.722
DOC_ANK_TNKS_1 684 691 PF00023 0.539
DOC_CKS1_1 884 889 PF01111 0.694
DOC_MAPK_gen_1 367 376 PF00069 0.589
DOC_MAPK_gen_1 57 65 PF00069 0.502
DOC_MAPK_gen_1 661 669 PF00069 0.518
DOC_MAPK_HePTP_8 70 82 PF00069 0.539
DOC_MAPK_MEF2A_6 1050 1058 PF00069 0.306
DOC_MAPK_MEF2A_6 57 65 PF00069 0.480
DOC_MAPK_MEF2A_6 696 705 PF00069 0.539
DOC_MAPK_MEF2A_6 73 82 PF00069 0.479
DOC_PP1_RVXF_1 739 745 PF00149 0.464
DOC_PP2B_LxvP_1 328 331 PF13499 0.477
DOC_PP2B_LxvP_1 374 377 PF13499 0.582
DOC_PP2B_LxvP_1 737 740 PF13499 0.467
DOC_PP2B_LxvP_1 757 760 PF13499 0.575
DOC_PP4_FxxP_1 884 887 PF00568 0.755
DOC_USP7_MATH_1 1044 1048 PF00917 0.455
DOC_USP7_MATH_1 1064 1068 PF00917 0.428
DOC_USP7_MATH_1 1144 1148 PF00917 0.625
DOC_USP7_MATH_1 145 149 PF00917 0.548
DOC_USP7_MATH_1 375 379 PF00917 0.725
DOC_USP7_MATH_1 399 403 PF00917 0.712
DOC_USP7_MATH_1 408 412 PF00917 0.741
DOC_USP7_MATH_1 553 557 PF00917 0.600
DOC_USP7_MATH_1 639 643 PF00917 0.485
DOC_USP7_MATH_1 683 687 PF00917 0.506
DOC_USP7_MATH_1 809 813 PF00917 0.525
DOC_USP7_MATH_1 819 823 PF00917 0.555
DOC_USP7_MATH_1 834 838 PF00917 0.476
DOC_USP7_MATH_1 850 854 PF00917 0.763
DOC_USP7_MATH_1 958 962 PF00917 0.597
DOC_USP7_MATH_1 966 970 PF00917 0.565
DOC_USP7_UBL2_3 243 247 PF12436 0.506
DOC_USP7_UBL2_3 361 365 PF12436 0.699
DOC_USP7_UBL2_3 531 535 PF12436 0.699
DOC_WW_Pin1_4 1012 1017 PF00397 0.730
DOC_WW_Pin1_4 1040 1045 PF00397 0.448
DOC_WW_Pin1_4 210 215 PF00397 0.470
DOC_WW_Pin1_4 220 225 PF00397 0.427
DOC_WW_Pin1_4 259 264 PF00397 0.573
DOC_WW_Pin1_4 360 365 PF00397 0.782
DOC_WW_Pin1_4 426 431 PF00397 0.727
DOC_WW_Pin1_4 649 654 PF00397 0.605
DOC_WW_Pin1_4 745 750 PF00397 0.491
DOC_WW_Pin1_4 772 777 PF00397 0.536
DOC_WW_Pin1_4 858 863 PF00397 0.710
DOC_WW_Pin1_4 883 888 PF00397 0.762
LIG_14-3-3_CanoR_1 298 306 PF00244 0.469
LIG_14-3-3_CanoR_1 341 345 PF00244 0.656
LIG_14-3-3_CanoR_1 670 675 PF00244 0.588
LIG_14-3-3_CanoR_1 696 705 PF00244 0.539
LIG_14-3-3_CanoR_1 770 774 PF00244 0.545
LIG_14-3-3_CanoR_1 949 954 PF00244 0.600
LIG_14-3-3_CanoR_1 97 106 PF00244 0.547
LIG_BIR_III_2 859 863 PF00653 0.702
LIG_BRCT_BRCA1_1 1066 1070 PF00533 0.346
LIG_BRCT_BRCA1_1 1105 1109 PF00533 0.459
LIG_Clathr_ClatBox_1 617 621 PF01394 0.524
LIG_deltaCOP1_diTrp_1 743 750 PF00928 0.464
LIG_EVH1_2 547 551 PF00568 0.644
LIG_EVH1_2 746 750 PF00568 0.459
LIG_FHA_1 1028 1034 PF00498 0.307
LIG_FHA_1 160 166 PF00498 0.485
LIG_FHA_1 182 188 PF00498 0.422
LIG_FHA_1 357 363 PF00498 0.735
LIG_FHA_1 65 71 PF00498 0.534
LIG_FHA_1 650 656 PF00498 0.634
LIG_FHA_1 669 675 PF00498 0.565
LIG_FHA_1 801 807 PF00498 0.505
LIG_FHA_1 869 875 PF00498 0.724
LIG_FHA_1 931 937 PF00498 0.623
LIG_FHA_2 105 111 PF00498 0.464
LIG_FHA_2 131 137 PF00498 0.460
LIG_FHA_2 283 289 PF00498 0.446
LIG_FHA_2 51 57 PF00498 0.524
LIG_FHA_2 591 597 PF00498 0.539
LIG_FHA_2 607 613 PF00498 0.539
LIG_FHA_2 822 828 PF00498 0.460
LIG_G3BP_FGDF_1 1018 1023 PF02136 0.414
LIG_GBD_Chelix_1 718 726 PF00786 0.306
LIG_Integrin_RGD_1 485 487 PF01839 0.472
LIG_LIR_Apic_2 706 712 PF02991 0.432
LIG_LIR_Apic_2 743 747 PF02991 0.470
LIG_LIR_Apic_2 952 958 PF02991 0.640
LIG_LIR_Gen_1 1091 1097 PF02991 0.678
LIG_LIR_Gen_1 320 331 PF02991 0.459
LIG_LIR_Gen_1 454 465 PF02991 0.525
LIG_LIR_Gen_1 564 573 PF02991 0.502
LIG_LIR_Gen_1 748 758 PF02991 0.459
LIG_LIR_LC3C_4 66 70 PF02991 0.539
LIG_LIR_Nem_3 1051 1055 PF02991 0.381
LIG_LIR_Nem_3 1091 1096 PF02991 0.695
LIG_LIR_Nem_3 301 306 PF02991 0.495
LIG_LIR_Nem_3 320 326 PF02991 0.464
LIG_LIR_Nem_3 454 460 PF02991 0.522
LIG_LIR_Nem_3 564 569 PF02991 0.555
LIG_LIR_Nem_3 706 710 PF02991 0.478
LIG_LIR_Nem_3 748 753 PF02991 0.459
LIG_LYPXL_yS_3 14 17 PF13949 0.477
LIG_NRBOX 568 574 PF00104 0.502
LIG_NRBOX 619 625 PF00104 0.493
LIG_PCNA_yPIPBox_3 142 156 PF02747 0.539
LIG_PDZ_Class_1 1153 1158 PF00595 0.618
LIG_Pex14_1 664 668 PF04695 0.510
LIG_Pex14_1 707 711 PF04695 0.446
LIG_Pex14_2 784 788 PF04695 0.446
LIG_SH2_CRK 605 609 PF00017 0.446
LIG_SH2_CRK 698 702 PF00017 0.530
LIG_SH2_CRK 955 959 PF00017 0.711
LIG_SH2_NCK_1 627 631 PF00017 0.459
LIG_SH2_NCK_1 698 702 PF00017 0.539
LIG_SH2_NCK_1 825 829 PF00017 0.464
LIG_SH2_PTP2 30 33 PF00017 0.459
LIG_SH2_PTP2 79 82 PF00017 0.507
LIG_SH2_SRC 1122 1125 PF00017 0.602
LIG_SH2_SRC 687 690 PF00017 0.446
LIG_SH2_STAP1 1149 1153 PF00017 0.666
LIG_SH2_STAP1 344 348 PF00017 0.650
LIG_SH2_STAP1 613 617 PF00017 0.528
LIG_SH2_STAP1 953 957 PF00017 0.586
LIG_SH2_STAT5 239 242 PF00017 0.549
LIG_SH2_STAT5 30 33 PF00017 0.446
LIG_SH2_STAT5 459 462 PF00017 0.521
LIG_SH2_STAT5 585 588 PF00017 0.476
LIG_SH2_STAT5 598 601 PF00017 0.407
LIG_SH2_STAT5 607 610 PF00017 0.446
LIG_SH2_STAT5 668 671 PF00017 0.518
LIG_SH2_STAT5 687 690 PF00017 0.446
LIG_SH2_STAT5 79 82 PF00017 0.471
LIG_SH2_STAT5 825 828 PF00017 0.503
LIG_SH2_STAT6 456 460 PF00017 0.447
LIG_SH3_1 1134 1140 PF00018 0.691
LIG_SH3_2 1121 1126 PF14604 0.639
LIG_SH3_3 1118 1124 PF00018 0.520
LIG_SH3_3 1133 1139 PF00018 0.584
LIG_SH3_3 424 430 PF00018 0.759
LIG_SH3_3 447 453 PF00018 0.670
LIG_SH3_3 541 547 PF00018 0.744
LIG_SH3_3 576 582 PF00018 0.446
LIG_SH3_3 743 749 PF00018 0.491
LIG_SH3_3 801 807 PF00018 0.437
LIG_SH3_3 940 946 PF00018 0.676
LIG_SH3_3 954 960 PF00018 0.657
LIG_SH3_CIN85_PxpxPR_1 883 888 PF14604 0.711
LIG_SUMO_SIM_anti_2 461 466 PF11976 0.587
LIG_SUMO_SIM_anti_2 915 921 PF11976 0.581
LIG_SUMO_SIM_anti_2 938 945 PF11976 0.612
LIG_SUMO_SIM_anti_2 961 967 PF11976 0.613
LIG_SUMO_SIM_par_1 332 338 PF11976 0.502
LIG_SUMO_SIM_par_1 66 71 PF11976 0.506
LIG_SUMO_SIM_par_1 716 721 PF11976 0.539
LIG_TRAF2_1 53 56 PF00917 0.446
LIG_TYR_ITIM 603 608 PF00017 0.446
LIG_TYR_ITIM 77 82 PF00017 0.502
MOD_CDC14_SPxK_1 213 216 PF00782 0.464
MOD_CDK_SPK_2 360 365 PF00069 0.659
MOD_CDK_SPK_2 883 888 PF00069 0.691
MOD_CDK_SPxK_1 210 216 PF00069 0.464
MOD_CDK_SPxK_1 883 889 PF00069 0.739
MOD_CDK_SPxxK_3 360 367 PF00069 0.666
MOD_CDK_SPxxK_3 888 895 PF00069 0.713
MOD_CK1_1 1042 1048 PF00069 0.516
MOD_CK1_1 1082 1088 PF00069 0.696
MOD_CK1_1 1091 1097 PF00069 0.690
MOD_CK1_1 223 229 PF00069 0.446
MOD_CK1_1 379 385 PF00069 0.762
MOD_CK1_1 429 435 PF00069 0.708
MOD_CK1_1 468 474 PF00069 0.552
MOD_CK1_1 557 563 PF00069 0.455
MOD_CK1_1 699 705 PF00069 0.452
MOD_CK1_1 915 921 PF00069 0.662
MOD_CK1_1 977 983 PF00069 0.617
MOD_CK2_1 130 136 PF00069 0.456
MOD_CK2_1 282 288 PF00069 0.457
MOD_CK2_1 339 345 PF00069 0.638
MOD_CK2_1 408 414 PF00069 0.722
MOD_CK2_1 50 56 PF00069 0.501
MOD_CK2_1 507 513 PF00069 0.694
MOD_CK2_1 606 612 PF00069 0.464
MOD_CK2_1 683 689 PF00069 0.562
MOD_CK2_1 821 827 PF00069 0.460
MOD_CK2_1 918 924 PF00069 0.679
MOD_CK2_1 936 942 PF00069 0.548
MOD_Cter_Amidation 533 536 PF01082 0.495
MOD_Cter_Amidation 982 985 PF01082 0.495
MOD_Cter_Amidation 995 998 PF01082 0.499
MOD_GlcNHglycan 101 104 PF01048 0.340
MOD_GlcNHglycan 1081 1084 PF01048 0.446
MOD_GlcNHglycan 1101 1104 PF01048 0.220
MOD_GlcNHglycan 1145 1149 PF01048 0.458
MOD_GlcNHglycan 119 123 PF01048 0.259
MOD_GlcNHglycan 300 303 PF01048 0.339
MOD_GlcNHglycan 308 311 PF01048 0.339
MOD_GlcNHglycan 385 388 PF01048 0.541
MOD_GlcNHglycan 401 404 PF01048 0.532
MOD_GlcNHglycan 454 457 PF01048 0.458
MOD_GlcNHglycan 496 499 PF01048 0.476
MOD_GlcNHglycan 588 591 PF01048 0.275
MOD_GlcNHglycan 641 644 PF01048 0.364
MOD_GlcNHglycan 656 659 PF01048 0.406
MOD_GlcNHglycan 821 824 PF01048 0.350
MOD_GlcNHglycan 836 839 PF01048 0.333
MOD_GlcNHglycan 914 917 PF01048 0.397
MOD_GlcNHglycan 920 923 PF01048 0.356
MOD_GlcNHglycan 988 992 PF01048 0.591
MOD_GSK3_1 1027 1034 PF00069 0.397
MOD_GSK3_1 1035 1042 PF00069 0.580
MOD_GSK3_1 1044 1051 PF00069 0.471
MOD_GSK3_1 1099 1106 PF00069 0.451
MOD_GSK3_1 114 121 PF00069 0.535
MOD_GSK3_1 181 188 PF00069 0.546
MOD_GSK3_1 216 223 PF00069 0.464
MOD_GSK3_1 274 281 PF00069 0.426
MOD_GSK3_1 349 356 PF00069 0.721
MOD_GSK3_1 375 382 PF00069 0.722
MOD_GSK3_1 399 406 PF00069 0.752
MOD_GSK3_1 421 428 PF00069 0.706
MOD_GSK3_1 553 560 PF00069 0.559
MOD_GSK3_1 586 593 PF00069 0.539
MOD_GSK3_1 64 71 PF00069 0.552
MOD_GSK3_1 699 706 PF00069 0.433
MOD_GSK3_1 819 826 PF00069 0.532
MOD_GSK3_1 850 857 PF00069 0.756
MOD_GSK3_1 945 952 PF00069 0.639
MOD_N-GLC_1 1107 1112 PF02516 0.258
MOD_N-GLC_1 266 271 PF02516 0.361
MOD_N-GLC_1 306 311 PF02516 0.343
MOD_N-GLC_1 809 814 PF02516 0.263
MOD_N-GLC_1 868 873 PF02516 0.564
MOD_NEK2_1 1027 1032 PF00069 0.257
MOD_NEK2_1 1039 1044 PF00069 0.449
MOD_NEK2_1 1130 1135 PF00069 0.648
MOD_NEK2_1 120 125 PF00069 0.465
MOD_NEK2_1 280 285 PF00069 0.491
MOD_NEK2_1 296 301 PF00069 0.401
MOD_NEK2_1 306 311 PF00069 0.515
MOD_NEK2_1 324 329 PF00069 0.446
MOD_NEK2_1 669 674 PF00069 0.448
MOD_NEK2_1 68 73 PF00069 0.448
MOD_NEK2_1 703 708 PF00069 0.524
MOD_NEK2_1 769 774 PF00069 0.500
MOD_NEK2_1 780 785 PF00069 0.435
MOD_PIKK_1 130 136 PF00454 0.506
MOD_PIKK_1 145 151 PF00454 0.389
MOD_PIKK_1 296 302 PF00454 0.459
MOD_PIKK_1 50 56 PF00454 0.464
MOD_PIKK_1 677 683 PF00454 0.433
MOD_PIKK_1 974 980 PF00454 0.616
MOD_PK_1 57 63 PF00069 0.522
MOD_PKA_1 340 346 PF00069 0.716
MOD_PKA_2 1088 1094 PF00069 0.659
MOD_PKA_2 340 346 PF00069 0.630
MOD_PKA_2 669 675 PF00069 0.611
MOD_PKA_2 769 775 PF00069 0.493
MOD_PKA_2 974 980 PF00069 0.621
MOD_PKB_1 1000 1008 PF00069 0.664
MOD_PKB_1 949 957 PF00069 0.619
MOD_PKB_1 985 993 PF00069 0.703
MOD_Plk_1 1035 1041 PF00069 0.459
MOD_Plk_1 1144 1150 PF00069 0.614
MOD_Plk_1 809 815 PF00069 0.391
MOD_Plk_1 930 936 PF00069 0.615
MOD_Plk_4 1035 1041 PF00069 0.347
MOD_Plk_4 1044 1050 PF00069 0.406
MOD_Plk_4 1088 1094 PF00069 0.674
MOD_Plk_4 120 126 PF00069 0.520
MOD_Plk_4 13 19 PF00069 0.530
MOD_Plk_4 274 280 PF00069 0.502
MOD_Plk_4 353 359 PF00069 0.754
MOD_Plk_4 465 471 PF00069 0.538
MOD_Plk_4 580 586 PF00069 0.490
MOD_Plk_4 590 596 PF00069 0.486
MOD_Plk_4 64 70 PF00069 0.506
MOD_Plk_4 800 806 PF00069 0.443
MOD_Plk_4 915 921 PF00069 0.691
MOD_Plk_4 936 942 PF00069 0.640
MOD_Plk_4 960 966 PF00069 0.686
MOD_ProDKin_1 1012 1018 PF00069 0.727
MOD_ProDKin_1 1040 1046 PF00069 0.449
MOD_ProDKin_1 210 216 PF00069 0.470
MOD_ProDKin_1 220 226 PF00069 0.427
MOD_ProDKin_1 259 265 PF00069 0.573
MOD_ProDKin_1 360 366 PF00069 0.782
MOD_ProDKin_1 426 432 PF00069 0.729
MOD_ProDKin_1 649 655 PF00069 0.574
MOD_ProDKin_1 745 751 PF00069 0.491
MOD_ProDKin_1 772 778 PF00069 0.536
MOD_ProDKin_1 858 864 PF00069 0.709
MOD_ProDKin_1 883 889 PF00069 0.764
MOD_SUMO_for_1 740 743 PF00179 0.524
MOD_SUMO_rev_2 288 294 PF00179 0.449
MOD_SUMO_rev_2 515 525 PF00179 0.669
TRG_DiLeu_BaEn_2 688 694 PF01217 0.446
TRG_DiLeu_BaLyEn_6 613 618 PF01217 0.501
TRG_DiLeu_BaLyEn_6 619 624 PF01217 0.487
TRG_ENDOCYTIC_2 14 17 PF00928 0.469
TRG_ENDOCYTIC_2 30 33 PF00928 0.398
TRG_ENDOCYTIC_2 457 460 PF00928 0.500
TRG_ENDOCYTIC_2 605 608 PF00928 0.446
TRG_ENDOCYTIC_2 627 630 PF00928 0.467
TRG_ENDOCYTIC_2 698 701 PF00928 0.508
TRG_ENDOCYTIC_2 710 713 PF00928 0.435
TRG_ENDOCYTIC_2 79 82 PF00928 0.477
TRG_ER_diArg_1 1111 1114 PF00400 0.539
TRG_ER_diArg_1 368 370 PF00400 0.737
TRG_ER_diArg_1 371 373 PF00400 0.759
TRG_ER_diArg_1 887 889 PF00400 0.852
TRG_ER_diArg_1 95 98 PF00400 0.467
TRG_ER_diArg_1 984 987 PF00400 0.712
TRG_NLS_Bipartite_1 984 1001 PF00514 0.626
TRG_NLS_MonoExtN_4 994 1001 PF00514 0.622
TRG_Pf-PMV_PEXEL_1 142 146 PF00026 0.299
TRG_Pf-PMV_PEXEL_1 616 621 PF00026 0.281
TRG_Pf-PMV_PEXEL_1 762 767 PF00026 0.285

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCR5 Leptomonas seymouri 56% 100%
A0A0S4JAB4 Bodo saltans 34% 100%
A0A3S5H716 Leishmania donovani 99% 100%
A0A422NS66 Trypanosoma rangeli 43% 100%
A4H970 Leishmania braziliensis 68% 95%
C9ZP82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 100%
E9AR87 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QE76 Leishmania major 91% 100%
V5AZC6 Trypanosoma cruzi 39% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS