Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HXE8_LEIIN

TriTrypDb:

LINF_170014000

Length:

1284

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0032300	mismatch repair complex	2	7
GO:0032991	protein-containing complex	1	7
GO:0032389	MutLalpha complex	3	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

A4HXE8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HXE8

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006298	mismatch repair	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016462	pyrophosphatase activity	5	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0016887	ATP hydrolysis activity	7	7
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140299	small molecule sensor activity	1	7
GO:0140612	DNA damage sensor activity	2	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:0140664	ATP-dependent DNA damage sensor activity	3	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	196	200	PF00656	0.658
CLV_C14_Caspase3-7	25	29	PF00656	0.629
CLV_C14_Caspase3-7	473	477	PF00656	0.431
CLV_NRD_NRD_1	1045	1047	PF00675	0.688
CLV_NRD_NRD_1	1051	1053	PF00675	0.593
CLV_NRD_NRD_1	283	285	PF00675	0.521
CLV_NRD_NRD_1	298	300	PF00675	0.349
CLV_NRD_NRD_1	369	371	PF00675	0.663
CLV_NRD_NRD_1	441	443	PF00675	0.767
CLV_NRD_NRD_1	451	453	PF00675	0.653
CLV_NRD_NRD_1	480	482	PF00675	0.732
CLV_NRD_NRD_1	672	674	PF00675	0.644
CLV_NRD_NRD_1	761	763	PF00675	0.721
CLV_NRD_NRD_1	807	809	PF00675	0.721
CLV_NRD_NRD_1	88	90	PF00675	0.477
CLV_NRD_NRD_1	881	883	PF00675	0.710
CLV_NRD_NRD_1	940	942	PF00675	0.596
CLV_PCSK_FUR_1	296	300	PF00082	0.409
CLV_PCSK_FUR_1	478	482	PF00082	0.681
CLV_PCSK_KEX2_1	1051	1053	PF00082	0.608
CLV_PCSK_KEX2_1	109	111	PF00082	0.524
CLV_PCSK_KEX2_1	282	284	PF00082	0.536
CLV_PCSK_KEX2_1	298	300	PF00082	0.344
CLV_PCSK_KEX2_1	369	371	PF00082	0.711
CLV_PCSK_KEX2_1	441	443	PF00082	0.767
CLV_PCSK_KEX2_1	451	453	PF00082	0.653
CLV_PCSK_KEX2_1	480	482	PF00082	0.732
CLV_PCSK_KEX2_1	672	674	PF00082	0.644
CLV_PCSK_KEX2_1	760	762	PF00082	0.766
CLV_PCSK_KEX2_1	807	809	PF00082	0.721
CLV_PCSK_KEX2_1	87	89	PF00082	0.480
CLV_PCSK_KEX2_1	881	883	PF00082	0.710
CLV_PCSK_PC1ET2_1	109	111	PF00082	0.524
CLV_PCSK_PC1ET2_1	760	762	PF00082	0.766
CLV_PCSK_SKI1_1	1046	1050	PF00082	0.682
CLV_PCSK_SKI1_1	1162	1166	PF00082	0.612
CLV_PCSK_SKI1_1	224	228	PF00082	0.408
CLV_PCSK_SKI1_1	232	236	PF00082	0.384
CLV_PCSK_SKI1_1	441	445	PF00082	0.720
CLV_PCSK_SKI1_1	553	557	PF00082	0.583
CLV_PCSK_SKI1_1	672	676	PF00082	0.667
CLV_PCSK_SKI1_1	762	766	PF00082	0.641
CLV_PCSK_SKI1_1	869	873	PF00082	0.656
CLV_PCSK_SKI1_1	941	945	PF00082	0.566
CLV_Separin_Metazoa	1010	1014	PF03568	0.410
DEG_APCC_DBOX_1	205	213	PF00400	0.684
DEG_APCC_DBOX_1	218	226	PF00400	0.575
DEG_SPOP_SBC_1	1216	1220	PF00917	0.416
DEG_SPOP_SBC_1	702	706	PF00917	0.581
DOC_CKS1_1	1040	1045	PF01111	0.404
DOC_CKS1_1	522	527	PF01111	0.494
DOC_CKS1_1	698	703	PF01111	0.532
DOC_CKS1_1	949	954	PF01111	0.496
DOC_CYCLIN_RxL_1	376	386	PF00134	0.495
DOC_CYCLIN_RxL_1	866	874	PF00134	0.462
DOC_CYCLIN_yCln2_LP_2	1199	1205	PF00134	0.476
DOC_CYCLIN_yCln2_LP_2	317	323	PF00134	0.388
DOC_CYCLIN_yCln2_LP_2	65	71	PF00134	0.675
DOC_MAPK_gen_1	1237	1245	PF00069	0.346
DOC_MAPK_gen_1	217	225	PF00069	0.679
DOC_MAPK_gen_1	807	813	PF00069	0.512
DOC_MAPK_gen_1	992	1001	PF00069	0.337
DOC_MAPK_JIP1_4	116	122	PF00069	0.649
DOC_MAPK_MEF2A_6	241	248	PF00069	0.692
DOC_PP1_RVXF_1	1121	1128	PF00149	0.468
DOC_PP1_RVXF_1	992	998	PF00149	0.329
DOC_PP2B_LxvP_1	1224	1227	PF13499	0.386
DOC_PP2B_LxvP_1	165	168	PF13499	0.573
DOC_PP2B_LxvP_1	317	320	PF13499	0.388
DOC_PP2B_LxvP_1	65	68	PF13499	0.688
DOC_PP4_FxxP_1	1192	1195	PF00568	0.511
DOC_PP4_FxxP_1	522	525	PF00568	0.488
DOC_USP7_MATH_1	1035	1039	PF00917	0.513
DOC_USP7_MATH_1	1071	1075	PF00917	0.580
DOC_USP7_MATH_1	1076	1080	PF00917	0.495
DOC_USP7_MATH_1	1126	1130	PF00917	0.496
DOC_USP7_MATH_1	1187	1191	PF00917	0.425
DOC_USP7_MATH_1	1210	1214	PF00917	0.438
DOC_USP7_MATH_1	1216	1220	PF00917	0.411
DOC_USP7_MATH_1	1253	1257	PF00917	0.388
DOC_USP7_MATH_1	131	135	PF00917	0.686
DOC_USP7_MATH_1	155	159	PF00917	0.704
DOC_USP7_MATH_1	189	193	PF00917	0.765
DOC_USP7_MATH_1	288	292	PF00917	0.648
DOC_USP7_MATH_1	339	343	PF00917	0.518
DOC_USP7_MATH_1	462	466	PF00917	0.559
DOC_USP7_MATH_1	488	492	PF00917	0.558
DOC_USP7_MATH_1	541	545	PF00917	0.528
DOC_USP7_MATH_1	659	663	PF00917	0.443
DOC_USP7_MATH_1	830	834	PF00917	0.550
DOC_USP7_MATH_1	932	936	PF00917	0.448
DOC_WW_Pin1_4	1039	1044	PF00397	0.461
DOC_WW_Pin1_4	1067	1072	PF00397	0.588
DOC_WW_Pin1_4	1217	1222	PF00397	0.520
DOC_WW_Pin1_4	1278	1283	PF00397	0.472
DOC_WW_Pin1_4	158	163	PF00397	0.697
DOC_WW_Pin1_4	240	245	PF00397	0.609
DOC_WW_Pin1_4	466	471	PF00397	0.506
DOC_WW_Pin1_4	495	500	PF00397	0.585
DOC_WW_Pin1_4	521	526	PF00397	0.575
DOC_WW_Pin1_4	545	550	PF00397	0.591
DOC_WW_Pin1_4	697	702	PF00397	0.616
DOC_WW_Pin1_4	703	708	PF00397	0.569
DOC_WW_Pin1_4	806	811	PF00397	0.547
DOC_WW_Pin1_4	850	855	PF00397	0.553
DOC_WW_Pin1_4	945	950	PF00397	0.438
LIG_14-3-3_CanoR_1	1017	1024	PF00244	0.492
LIG_14-3-3_CanoR_1	1036	1040	PF00244	0.419
LIG_14-3-3_CanoR_1	1089	1099	PF00244	0.335
LIG_14-3-3_CanoR_1	1162	1168	PF00244	0.367
LIG_14-3-3_CanoR_1	1171	1175	PF00244	0.349
LIG_14-3-3_CanoR_1	1255	1264	PF00244	0.277
LIG_14-3-3_CanoR_1	1274	1282	PF00244	0.391
LIG_14-3-3_CanoR_1	18	26	PF00244	0.625
LIG_14-3-3_CanoR_1	224	229	PF00244	0.685
LIG_14-3-3_CanoR_1	282	287	PF00244	0.655
LIG_14-3-3_CanoR_1	340	344	PF00244	0.517
LIG_14-3-3_CanoR_1	379	384	PF00244	0.509
LIG_14-3-3_CanoR_1	388	393	PF00244	0.480
LIG_14-3-3_CanoR_1	397	404	PF00244	0.422
LIG_14-3-3_CanoR_1	47	53	PF00244	0.673
LIG_14-3-3_CanoR_1	553	558	PF00244	0.381
LIG_14-3-3_CanoR_1	576	581	PF00244	0.512
LIG_14-3-3_CanoR_1	654	664	PF00244	0.523
LIG_14-3-3_CanoR_1	673	679	PF00244	0.551
LIG_14-3-3_CanoR_1	761	765	PF00244	0.478
LIG_14-3-3_CanoR_1	8	17	PF00244	0.711
LIG_14-3-3_CanoR_1	808	814	PF00244	0.507
LIG_14-3-3_CanoR_1	87	94	PF00244	0.650
LIG_14-3-3_CanoR_1	933	937	PF00244	0.459
LIG_Actin_WH2_2	1077	1093	PF00022	0.362
LIG_Actin_WH2_2	1157	1173	PF00022	0.355
LIG_Actin_WH2_2	2	20	PF00022	0.716
LIG_AP2alpha_1	26	30	PF02296	0.676
LIG_APCC_ABBA_1	633	638	PF00400	0.383
LIG_APCC_ABBA_1	664	669	PF00400	0.451
LIG_BIR_III_4	329	333	PF00653	0.469
LIG_BRCT_BRCA1_1	19	23	PF00533	0.707
LIG_BRCT_BRCA1_1	543	547	PF00533	0.511
LIG_BRCT_BRCA1_1	904	908	PF00533	0.509
LIG_CaM_IQ_9	727	742	PF13499	0.490
LIG_CaM_NSCaTE_8	599	606	PF13499	0.442
LIG_CSL_BTD_1	496	499	PF09270	0.530
LIG_CSL_BTD_1	892	895	PF09270	0.548
LIG_CtBP_PxDLS_1	380	384	PF00389	0.481
LIG_DLG_GKlike_1	379	387	PF00625	0.434
LIG_EH1_1	1052	1060	PF00400	0.408
LIG_FHA_1	1145	1151	PF00498	0.318
LIG_FHA_1	1198	1204	PF00498	0.508
LIG_FHA_1	241	247	PF00498	0.664
LIG_FHA_1	373	379	PF00498	0.558
LIG_FHA_1	507	513	PF00498	0.466
LIG_FHA_1	673	679	PF00498	0.484
LIG_FHA_1	75	81	PF00498	0.664
LIG_FHA_1	774	780	PF00498	0.626
LIG_FHA_2	1027	1033	PF00498	0.496
LIG_FHA_2	1091	1097	PF00498	0.348
LIG_FHA_2	1171	1177	PF00498	0.344
LIG_FHA_2	23	29	PF00498	0.592
LIG_FHA_2	269	275	PF00498	0.720
LIG_FHA_2	442	448	PF00498	0.483
LIG_FHA_2	471	477	PF00498	0.477
LIG_FHA_2	496	502	PF00498	0.561
LIG_FHA_2	703	709	PF00498	0.549
LIG_FHA_2	8	14	PF00498	0.729
LIG_FHA_2	819	825	PF00498	0.512
LIG_FHA_2	88	94	PF00498	0.691
LIG_Integrin_RGD_1	901	903	PF01839	0.707
LIG_LIR_Apic_2	1189	1195	PF02991	0.496
LIG_LIR_Gen_1	1228	1235	PF02991	0.384
LIG_LIR_Gen_1	1276	1283	PF02991	0.398
LIG_LIR_Gen_1	27	38	PF02991	0.687
LIG_LIR_Gen_1	556	562	PF02991	0.439
LIG_LIR_Gen_1	662	671	PF02991	0.430
LIG_LIR_Gen_1	996	1006	PF02991	0.360
LIG_LIR_Nem_3	1139	1145	PF02991	0.405
LIG_LIR_Nem_3	121	126	PF02991	0.667
LIG_LIR_Nem_3	1228	1233	PF02991	0.385
LIG_LIR_Nem_3	1276	1280	PF02991	0.367
LIG_LIR_Nem_3	20	26	PF02991	0.648
LIG_LIR_Nem_3	243	248	PF02991	0.662
LIG_LIR_Nem_3	251	257	PF02991	0.681
LIG_LIR_Nem_3	27	33	PF02991	0.624
LIG_LIR_Nem_3	544	550	PF02991	0.594
LIG_LIR_Nem_3	556	561	PF02991	0.395
LIG_LIR_Nem_3	662	666	PF02991	0.434
LIG_LIR_Nem_3	996	1001	PF02991	0.345
LIG_MAD2	693	701	PF02301	0.513
LIG_MAD2	740	748	PF02301	0.436
LIG_MYND_1	1223	1227	PF01753	0.419
LIG_MYND_3	38	42	PF01753	0.642
LIG_PCNA_TLS_4	992	999	PF02747	0.330
LIG_Pex14_1	1102	1106	PF04695	0.331
LIG_Pex14_1	939	943	PF04695	0.378
LIG_Pex14_2	1188	1192	PF04695	0.499
LIG_Pex14_2	1230	1234	PF04695	0.384
LIG_Pex14_2	26	30	PF04695	0.676
LIG_Pex14_2	518	522	PF04695	0.562
LIG_Pex14_2	997	1001	PF04695	0.348
LIG_Rb_LxCxE_1	1256	1278	PF01857	0.412
LIG_REV1ctd_RIR_1	1231	1241	PF16727	0.341
LIG_RPA_C_Fungi	1047	1059	PF08784	0.584
LIG_SH2_CRK	254	258	PF00017	0.518
LIG_SH2_CRK	601	605	PF00017	0.533
LIG_SH2_PTP2	245	248	PF00017	0.625
LIG_SH2_SRC	641	644	PF00017	0.515
LIG_SH2_SRC	667	670	PF00017	0.520
LIG_SH2_SRC	753	756	PF00017	0.636
LIG_SH2_STAP1	1138	1142	PF00017	0.502
LIG_SH2_STAP1	667	671	PF00017	0.520
LIG_SH2_STAT3	736	739	PF00017	0.529
LIG_SH2_STAT5	1005	1008	PF00017	0.498
LIG_SH2_STAT5	1268	1271	PF00017	0.423
LIG_SH2_STAT5	190	193	PF00017	0.538
LIG_SH2_STAT5	245	248	PF00017	0.625
LIG_SH2_STAT5	322	325	PF00017	0.522
LIG_SH2_STAT5	641	644	PF00017	0.515
LIG_SH2_STAT5	736	739	PF00017	0.529
LIG_SH2_STAT5	753	756	PF00017	0.684
LIG_SH3_2	892	897	PF14604	0.702
LIG_SH3_2	949	954	PF14604	0.522
LIG_SH3_3	1003	1009	PF00018	0.497
LIG_SH3_3	1037	1043	PF00018	0.590
LIG_SH3_3	1079	1085	PF00018	0.445
LIG_SH3_3	1130	1136	PF00018	0.542
LIG_SH3_3	1147	1153	PF00018	0.375
LIG_SH3_3	1245	1251	PF00018	0.516
LIG_SH3_3	33	39	PF00018	0.612
LIG_SH3_3	374	380	PF00018	0.641
LIG_SH3_3	458	464	PF00018	0.518
LIG_SH3_3	509	515	PF00018	0.634
LIG_SH3_3	590	596	PF00018	0.527
LIG_SH3_3	616	622	PF00018	0.659
LIG_SH3_3	889	895	PF00018	0.718
LIG_SH3_3	946	952	PF00018	0.602
LIG_SH3_3	964	970	PF00018	0.619
LIG_SUMO_SIM_par_1	1222	1228	PF11976	0.514
LIG_SUMO_SIM_par_1	379	386	PF11976	0.665
LIG_SUMO_SIM_par_1	558	564	PF11976	0.552
LIG_SUMO_SIM_par_1	809	814	PF11976	0.709
LIG_TRAF2_1	1173	1176	PF00917	0.398
LIG_TRAF2_1	498	501	PF00917	0.708
LIG_TRAF2_1	723	726	PF00917	0.599
LIG_TRAF2_1	821	824	PF00917	0.641
LIG_WRC_WIRS_1	23	28	PF05994	0.538
MOD_CDK_SPxK_1	948	954	PF00069	0.520
MOD_CDK_SPxxK_3	1039	1046	PF00069	0.566
MOD_CK1_1	1072	1078	PF00069	0.598
MOD_CK1_1	1197	1203	PF00069	0.608
MOD_CK1_1	1256	1262	PF00069	0.303
MOD_CK1_1	158	164	PF00069	0.725
MOD_CK1_1	268	274	PF00069	0.543
MOD_CK1_1	349	355	PF00069	0.514
MOD_CK1_1	382	388	PF00069	0.643
MOD_CK1_1	465	471	PF00069	0.677
MOD_CK1_1	715	721	PF00069	0.577
MOD_CK1_1	763	769	PF00069	0.640
MOD_CK1_1	948	954	PF00069	0.555
MOD_CK1_1	956	962	PF00069	0.642
MOD_CK2_1	1026	1032	PF00069	0.654
MOD_CK2_1	1090	1096	PF00069	0.397
MOD_CK2_1	1170	1176	PF00069	0.442
MOD_CK2_1	268	274	PF00069	0.713
MOD_CK2_1	441	447	PF00069	0.691
MOD_CK2_1	495	501	PF00069	0.713
MOD_CK2_1	537	543	PF00069	0.579
MOD_CK2_1	818	824	PF00069	0.650
MOD_CK2_1	839	845	PF00069	0.638
MOD_CK2_1	87	93	PF00069	0.607
MOD_CK2_1	98	104	PF00069	0.520
MOD_Cter_Amidation	439	442	PF01082	0.656
MOD_GlcNHglycan	100	103	PF01048	0.677
MOD_GlcNHglycan	1026	1029	PF01048	0.612
MOD_GlcNHglycan	1071	1074	PF01048	0.718
MOD_GlcNHglycan	1128	1131	PF01048	0.586
MOD_GlcNHglycan	1189	1192	PF01048	0.567
MOD_GlcNHglycan	1196	1199	PF01048	0.614
MOD_GlcNHglycan	1258	1261	PF01048	0.295
MOD_GlcNHglycan	143	146	PF01048	0.621
MOD_GlcNHglycan	211	215	PF01048	0.620
MOD_GlcNHglycan	261	264	PF01048	0.763
MOD_GlcNHglycan	290	293	PF01048	0.520
MOD_GlcNHglycan	329	333	PF01048	0.654
MOD_GlcNHglycan	351	354	PF01048	0.533
MOD_GlcNHglycan	390	393	PF01048	0.661
MOD_GlcNHglycan	399	402	PF01048	0.604
MOD_GlcNHglycan	420	423	PF01048	0.545
MOD_GlcNHglycan	470	473	PF01048	0.697
MOD_GlcNHglycan	485	488	PF01048	0.621
MOD_GlcNHglycan	528	531	PF01048	0.628
MOD_GlcNHglycan	539	542	PF01048	0.793
MOD_GlcNHglycan	583	586	PF01048	0.702
MOD_GlcNHglycan	623	626	PF01048	0.741
MOD_GlcNHglycan	638	641	PF01048	0.530
MOD_GlcNHglycan	657	660	PF01048	0.586
MOD_GlcNHglycan	792	795	PF01048	0.664
MOD_GlcNHglycan	845	849	PF01048	0.738
MOD_GlcNHglycan	877	880	PF01048	0.588
MOD_GlcNHglycan	903	908	PF01048	0.718
MOD_GlcNHglycan	918	921	PF01048	0.633
MOD_GlcNHglycan	930	933	PF01048	0.573
MOD_GSK3_1	1024	1031	PF00069	0.609
MOD_GSK3_1	1035	1042	PF00069	0.541
MOD_GSK3_1	1058	1065	PF00069	0.596
MOD_GSK3_1	1067	1074	PF00069	0.551
MOD_GSK3_1	1076	1083	PF00069	0.556
MOD_GSK3_1	1197	1204	PF00069	0.654
MOD_GSK3_1	1249	1256	PF00069	0.462
MOD_GSK3_1	189	196	PF00069	0.679
MOD_GSK3_1	379	386	PF00069	0.765
MOD_GSK3_1	388	395	PF00069	0.608
MOD_GSK3_1	462	469	PF00069	0.612
MOD_GSK3_1	495	502	PF00069	0.676
MOD_GSK3_1	537	544	PF00069	0.600
MOD_GSK3_1	576	583	PF00069	0.735
MOD_GSK3_1	655	662	PF00069	0.614
MOD_GSK3_1	674	681	PF00069	0.533
MOD_GSK3_1	697	704	PF00069	0.779
MOD_GSK3_1	756	763	PF00069	0.631
MOD_GSK3_1	836	843	PF00069	0.705
MOD_GSK3_1	846	853	PF00069	0.631
MOD_GSK3_1	871	878	PF00069	0.552
MOD_GSK3_1	912	919	PF00069	0.619
MOD_GSK3_1	924	931	PF00069	0.531
MOD_NEK2_1	1001	1006	PF00069	0.456
MOD_NEK2_1	1058	1063	PF00069	0.549
MOD_NEK2_1	1080	1085	PF00069	0.503
MOD_NEK2_1	1090	1095	PF00069	0.376
MOD_NEK2_1	1119	1124	PF00069	0.558
MOD_NEK2_1	1233	1238	PF00069	0.384
MOD_NEK2_1	248	253	PF00069	0.634
MOD_NEK2_1	321	326	PF00069	0.567
MOD_NEK2_1	328	333	PF00069	0.758
MOD_NEK2_1	381	386	PF00069	0.601
MOD_NEK2_1	457	462	PF00069	0.494
MOD_NEK2_1	528	533	PF00069	0.665
MOD_NEK2_1	636	641	PF00069	0.572
MOD_NEK2_1	674	679	PF00069	0.583
MOD_NEK2_1	790	795	PF00069	0.666
MOD_NEK2_1	871	876	PF00069	0.571
MOD_OGLYCOS	1217	1222	PF02709	0.491
MOD_PIKK_1	1210	1216	PF00454	0.527
MOD_PIKK_1	680	686	PF00454	0.633
MOD_PIKK_1	747	753	PF00454	0.646
MOD_PK_1	576	582	PF00069	0.655
MOD_PK_1	760	766	PF00069	0.497
MOD_PKA_1	282	288	PF00069	0.609
MOD_PKA_1	441	447	PF00069	0.643
MOD_PKA_1	672	678	PF00069	0.592
MOD_PKA_1	760	766	PF00069	0.558
MOD_PKA_1	87	93	PF00069	0.553
MOD_PKA_2	1035	1041	PF00069	0.695
MOD_PKA_2	1090	1096	PF00069	0.404
MOD_PKA_2	1170	1176	PF00069	0.437
MOD_PKA_2	1249	1255	PF00069	0.500
MOD_PKA_2	1273	1279	PF00069	0.446
MOD_PKA_2	155	161	PF00069	0.606
MOD_PKA_2	17	23	PF00069	0.560
MOD_PKA_2	259	265	PF00069	0.725
MOD_PKA_2	282	288	PF00069	0.611
MOD_PKA_2	339	345	PF00069	0.648
MOD_PKA_2	396	402	PF00069	0.611
MOD_PKA_2	441	447	PF00069	0.718
MOD_PKA_2	644	650	PF00069	0.655
MOD_PKA_2	672	678	PF00069	0.714
MOD_PKA_2	7	13	PF00069	0.628
MOD_PKA_2	760	766	PF00069	0.630
MOD_PKA_2	818	824	PF00069	0.650
MOD_PKA_2	87	93	PF00069	0.553
MOD_PKA_2	875	881	PF00069	0.559
MOD_PKA_2	896	902	PF00069	0.579
MOD_PKA_2	932	938	PF00069	0.491
MOD_PKA_2	953	959	PF00069	0.594
MOD_PKB_1	425	433	PF00069	0.632
MOD_Plk_1	131	137	PF00069	0.452
MOD_Plk_1	265	271	PF00069	0.538
MOD_Plk_1	334	340	PF00069	0.603
MOD_Plk_2-3	22	28	PF00069	0.539
MOD_Plk_4	1001	1007	PF00069	0.466
MOD_Plk_4	1225	1231	PF00069	0.418
MOD_Plk_4	339	345	PF00069	0.515
MOD_Plk_4	553	559	PF00069	0.538
MOD_Plk_4	659	665	PF00069	0.570
MOD_Plk_4	749	755	PF00069	0.659
MOD_Plk_4	785	791	PF00069	0.589
MOD_Plk_4	932	938	PF00069	0.452
MOD_ProDKin_1	1039	1045	PF00069	0.568
MOD_ProDKin_1	1067	1073	PF00069	0.751
MOD_ProDKin_1	1217	1223	PF00069	0.650
MOD_ProDKin_1	1278	1284	PF00069	0.602
MOD_ProDKin_1	158	164	PF00069	0.618
MOD_ProDKin_1	240	246	PF00069	0.501
MOD_ProDKin_1	466	472	PF00069	0.635
MOD_ProDKin_1	495	501	PF00069	0.744
MOD_ProDKin_1	521	527	PF00069	0.735
MOD_ProDKin_1	545	551	PF00069	0.750
MOD_ProDKin_1	697	703	PF00069	0.791
MOD_ProDKin_1	806	812	PF00069	0.690
MOD_ProDKin_1	850	856	PF00069	0.698
MOD_ProDKin_1	945	951	PF00069	0.556
MOD_SUMO_for_1	1155	1158	PF00179	0.492
MOD_SUMO_for_1	723	726	PF00179	0.647
MOD_SUMO_rev_2	690	695	PF00179	0.580
TRG_DiLeu_BaEn_1	218	223	PF01217	0.534
TRG_DiLeu_BaEn_1	301	306	PF01217	0.509
TRG_DiLeu_BaLyEn_6	1220	1225	PF01217	0.560
TRG_DiLeu_BaLyEn_6	221	226	PF01217	0.433
TRG_ENDOCYTIC_2	245	248	PF00928	0.625
TRG_ENDOCYTIC_2	254	257	PF00928	0.556
TRG_ENDOCYTIC_2	601	604	PF00928	0.595
TRG_ER_diArg_1	1051	1054	PF00400	0.583
TRG_ER_diArg_1	1088	1091	PF00400	0.397
TRG_ER_diArg_1	281	284	PF00400	0.646
TRG_ER_diArg_1	295	298	PF00400	0.469
TRG_ER_diArg_1	424	427	PF00400	0.598
TRG_ER_diArg_1	441	443	PF00400	0.725
TRG_ER_diArg_1	451	453	PF00400	0.566
TRG_ER_diArg_1	478	481	PF00400	0.616
TRG_ER_diArg_1	671	673	PF00400	0.570
TRG_ER_diArg_1	732	735	PF00400	0.555
TRG_ER_diArg_1	806	808	PF00400	0.733
TRG_ER_diArg_1	831	834	PF00400	0.622
TRG_ER_diArg_1	86	89	PF00400	0.600
TRG_ER_diArg_1	880	882	PF00400	0.639
TRG_ER_diArg_1	992	995	PF00400	0.381
TRG_Pf-PMV_PEXEL_1	735	739	PF00026	0.610
TRG_Pf-PMV_PEXEL_1	869	873	PF00026	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I053	Leptomonas seymouri	34%	94%
A0A3S7WUN6	Leishmania donovani	99%	100%
A4H916	Leishmania braziliensis	72%	100%
E9AR43	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%
Q4QEC0	Leishmania major	90%	100%