LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase - putative
Species:
Leishmania infantum
UniProt:
A4HX87_LEIIN
TriTrypDb:
LINF_170007400 *
Length:
1322

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Annotations by Jardim et al.

Receptors, receptor-type adenylate cyclase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 47, no: 29
NetGPI no yes: 0, no: 76
Cellular components
Term Name Level Count
GO:0110165 cellular anatomical entity 1 77
GO:0016020 membrane 2 70

Expansion

Sequence features

A4HX87
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX87

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 76
GO:0006163 purine nucleotide metabolic process 5 76
GO:0006164 purine nucleotide biosynthetic process 6 76
GO:0006171 cAMP biosynthetic process 8 76
GO:0006725 cellular aromatic compound metabolic process 3 76
GO:0006753 nucleoside phosphate metabolic process 4 76
GO:0006793 phosphorus metabolic process 3 76
GO:0006796 phosphate-containing compound metabolic process 4 76
GO:0006807 nitrogen compound metabolic process 2 76
GO:0007165 signal transduction 2 76
GO:0008152 metabolic process 1 76
GO:0009058 biosynthetic process 2 76
GO:0009117 nucleotide metabolic process 5 76
GO:0009150 purine ribonucleotide metabolic process 6 76
GO:0009152 purine ribonucleotide biosynthetic process 7 76
GO:0009165 nucleotide biosynthetic process 6 76
GO:0009187 cyclic nucleotide metabolic process 6 76
GO:0009190 cyclic nucleotide biosynthetic process 7 76
GO:0009259 ribonucleotide metabolic process 5 76
GO:0009260 ribonucleotide biosynthetic process 6 76
GO:0009987 cellular process 1 76
GO:0018130 heterocycle biosynthetic process 4 76
GO:0019438 aromatic compound biosynthetic process 4 76
GO:0019637 organophosphate metabolic process 3 76
GO:0019693 ribose phosphate metabolic process 4 76
GO:0034641 cellular nitrogen compound metabolic process 3 76
GO:0034654 nucleobase-containing compound biosynthetic process 4 76
GO:0035556 intracellular signal transduction 3 76
GO:0044237 cellular metabolic process 2 76
GO:0044238 primary metabolic process 2 76
GO:0044249 cellular biosynthetic process 3 76
GO:0044271 cellular nitrogen compound biosynthetic process 4 76
GO:0044281 small molecule metabolic process 2 76
GO:0046058 cAMP metabolic process 7 76
GO:0046390 ribose phosphate biosynthetic process 5 76
GO:0046483 heterocycle metabolic process 3 76
GO:0050789 regulation of biological process 2 76
GO:0050794 regulation of cellular process 3 76
GO:0052652 cyclic purine nucleotide metabolic process 6 76
GO:0055086 nucleobase-containing small molecule metabolic process 3 76
GO:0065007 biological regulation 1 76
GO:0071704 organic substance metabolic process 2 76
GO:0072521 purine-containing compound metabolic process 4 76
GO:0072522 purine-containing compound biosynthetic process 5 76
GO:0090407 organophosphate biosynthetic process 4 76
GO:1901135 carbohydrate derivative metabolic process 3 76
GO:1901137 carbohydrate derivative biosynthetic process 4 76
GO:1901293 nucleoside phosphate biosynthetic process 5 76
GO:1901360 organic cyclic compound metabolic process 3 76
GO:1901362 organic cyclic compound biosynthetic process 4 76
GO:1901564 organonitrogen compound metabolic process 3 76
GO:1901566 organonitrogen compound biosynthetic process 4 76
GO:1901576 organic substance biosynthetic process 3 76
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 65
GO:0016829 lyase activity 2 65
GO:0004016 adenylate cyclase activity 3 1
GO:0009975 cyclase activity 2 1
GO:0016849 phosphorus-oxygen lyase activity 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 304 308 PF00656 0.538
CLV_C14_Caspase3-7 622 626 PF00656 0.310
CLV_C14_Caspase3-7 844 848 PF00656 0.632
CLV_C14_Caspase3-7 905 909 PF00656 0.482
CLV_MEL_PAP_1 978 984 PF00089 0.273
CLV_NRD_NRD_1 1068 1070 PF00675 0.397
CLV_NRD_NRD_1 1236 1238 PF00675 0.609
CLV_NRD_NRD_1 1251 1253 PF00675 0.580
CLV_NRD_NRD_1 127 129 PF00675 0.613
CLV_NRD_NRD_1 1276 1278 PF00675 0.631
CLV_NRD_NRD_1 1306 1308 PF00675 0.440
CLV_NRD_NRD_1 348 350 PF00675 0.502
CLV_NRD_NRD_1 446 448 PF00675 0.580
CLV_PCSK_FUR_1 125 129 PF00082 0.605
CLV_PCSK_FUR_1 1304 1308 PF00082 0.400
CLV_PCSK_KEX2_1 1068 1070 PF00082 0.397
CLV_PCSK_KEX2_1 122 124 PF00082 0.623
CLV_PCSK_KEX2_1 1236 1238 PF00082 0.605
CLV_PCSK_KEX2_1 127 129 PF00082 0.613
CLV_PCSK_KEX2_1 1276 1278 PF00082 0.634
CLV_PCSK_KEX2_1 1304 1306 PF00082 0.440
CLV_PCSK_PC1ET2_1 122 124 PF00082 0.425
CLV_PCSK_PC7_1 123 129 PF00082 0.431
CLV_PCSK_SKI1_1 1165 1169 PF00082 0.435
CLV_PCSK_SKI1_1 128 132 PF00082 0.583
CLV_PCSK_SKI1_1 225 229 PF00082 0.496
CLV_PCSK_SKI1_1 426 430 PF00082 0.635
CLV_PCSK_SKI1_1 553 557 PF00082 0.540
CLV_PCSK_SKI1_1 667 671 PF00082 0.498
CLV_PCSK_SKI1_1 710 714 PF00082 0.566
CLV_PCSK_SKI1_1 930 934 PF00082 0.275
DEG_APCC_DBOX_1 709 717 PF00400 0.279
DEG_APCC_KENBOX_2 527 531 PF00400 0.247
DEG_SCF_FBW7_2 376 382 PF00400 0.234
DEG_SCF_FBW7_2 796 802 PF00400 0.469
DEG_SPOP_SBC_1 210 214 PF00917 0.445
DOC_CDC14_PxL_1 51 59 PF14671 0.454
DOC_CDC14_PxL_1 685 693 PF14671 0.233
DOC_CKS1_1 376 381 PF01111 0.239
DOC_CKS1_1 796 801 PF01111 0.406
DOC_CYCLIN_RxL_1 664 672 PF00134 0.241
DOC_CYCLIN_yCln2_LP_2 156 162 PF00134 0.361
DOC_CYCLIN_yCln2_LP_2 429 435 PF00134 0.410
DOC_MAPK_gen_1 125 134 PF00069 0.298
DOC_MAPK_gen_1 1252 1258 PF00069 0.613
DOC_MAPK_gen_1 39 46 PF00069 0.323
DOC_MAPK_HePTP_8 428 440 PF00069 0.411
DOC_MAPK_MEF2A_6 431 440 PF00069 0.428
DOC_MAPK_MEF2A_6 710 717 PF00069 0.314
DOC_MAPK_RevD_3 1055 1069 PF00069 0.529
DOC_MAPK_RevD_3 113 128 PF00069 0.259
DOC_PP1_RVXF_1 223 229 PF00149 0.419
DOC_PP1_RVXF_1 463 469 PF00149 0.374
DOC_PP1_RVXF_1 665 672 PF00149 0.287
DOC_PP1_RVXF_1 79 86 PF00149 0.343
DOC_PP2B_LxvP_1 156 159 PF13499 0.327
DOC_PP4_FxxP_1 519 522 PF00568 0.282
DOC_PP4_FxxP_1 533 536 PF00568 0.360
DOC_PP4_FxxP_1 588 591 PF00568 0.442
DOC_PP4_FxxP_1 64 67 PF00568 0.370
DOC_PP4_FxxP_1 698 701 PF00568 0.457
DOC_PP4_FxxP_1 728 731 PF00568 0.348
DOC_PP4_FxxP_1 85 88 PF00568 0.431
DOC_USP7_MATH_1 1167 1171 PF00917 0.668
DOC_USP7_MATH_1 1212 1216 PF00917 0.794
DOC_USP7_MATH_1 1224 1228 PF00917 0.760
DOC_USP7_MATH_1 1272 1276 PF00917 0.667
DOC_USP7_MATH_1 210 214 PF00917 0.443
DOC_USP7_MATH_1 303 307 PF00917 0.427
DOC_USP7_MATH_1 34 38 PF00917 0.397
DOC_USP7_MATH_1 554 558 PF00917 0.421
DOC_USP7_MATH_1 597 601 PF00917 0.456
DOC_USP7_MATH_1 67 71 PF00917 0.420
DOC_USP7_MATH_1 791 795 PF00917 0.355
DOC_USP7_MATH_1 913 917 PF00917 0.549
DOC_USP7_UBL2_3 291 295 PF12436 0.442
DOC_USP7_UBL2_3 49 53 PF12436 0.390
DOC_WW_Pin1_4 238 243 PF00397 0.418
DOC_WW_Pin1_4 375 380 PF00397 0.419
DOC_WW_Pin1_4 513 518 PF00397 0.324
DOC_WW_Pin1_4 678 683 PF00397 0.452
DOC_WW_Pin1_4 702 707 PF00397 0.334
DOC_WW_Pin1_4 792 797 PF00397 0.366
LIG_14-3-3_CanoR_1 1147 1154 PF00244 0.648
LIG_14-3-3_CanoR_1 1165 1170 PF00244 0.627
LIG_14-3-3_CanoR_1 1236 1241 PF00244 0.794
LIG_14-3-3_CanoR_1 125 134 PF00244 0.340
LIG_14-3-3_CanoR_1 211 218 PF00244 0.385
LIG_14-3-3_CanoR_1 265 275 PF00244 0.289
LIG_14-3-3_CanoR_1 349 353 PF00244 0.336
LIG_14-3-3_CanoR_1 553 562 PF00244 0.425
LIG_14-3-3_CanoR_1 583 589 PF00244 0.370
LIG_14-3-3_CanoR_1 667 672 PF00244 0.412
LIG_14-3-3_CanoR_1 753 757 PF00244 0.445
LIG_14-3-3_CanoR_1 915 923 PF00244 0.590
LIG_14-3-3_CanoR_1 965 971 PF00244 0.608
LIG_Actin_WH2_2 109 124 PF00022 0.240
LIG_Actin_WH2_2 431 449 PF00022 0.310
LIG_Actin_WH2_2 489 507 PF00022 0.230
LIG_Actin_WH2_2 570 585 PF00022 0.334
LIG_Actin_WH2_2 591 607 PF00022 0.344
LIG_AP2alpha_2 108 110 PF02296 0.217
LIG_APCC_ABBA_1 228 233 PF00400 0.290
LIG_APCC_ABBA_1 61 66 PF00400 0.435
LIG_BIR_II_1 1 5 PF00653 0.221
LIG_BIR_III_2 849 853 PF00653 0.614
LIG_BRCT_BRCA1_1 515 519 PF00533 0.216
LIG_BRCT_BRCA1_1 713 717 PF00533 0.389
LIG_deltaCOP1_diTrp_1 488 491 PF00928 0.232
LIG_eIF4E_1 688 694 PF01652 0.228
LIG_FHA_1 1011 1017 PF00498 0.487
LIG_FHA_1 112 118 PF00498 0.308
LIG_FHA_1 276 282 PF00498 0.449
LIG_FHA_1 320 326 PF00498 0.335
LIG_FHA_1 358 364 PF00498 0.391
LIG_FHA_1 435 441 PF00498 0.338
LIG_FHA_1 498 504 PF00498 0.312
LIG_FHA_1 631 637 PF00498 0.435
LIG_FHA_1 703 709 PF00498 0.351
LIG_FHA_1 760 766 PF00498 0.487
LIG_FHA_1 826 832 PF00498 0.387
LIG_FHA_1 927 933 PF00498 0.545
LIG_FHA_1 936 942 PF00498 0.480
LIG_FHA_1 961 967 PF00498 0.490
LIG_FHA_2 103 109 PF00498 0.424
LIG_FHA_2 1073 1079 PF00498 0.741
LIG_FHA_2 1083 1089 PF00498 0.780
LIG_FHA_2 239 245 PF00498 0.419
LIG_FHA_2 337 343 PF00498 0.404
LIG_FHA_2 618 624 PF00498 0.348
LIG_FHA_2 862 868 PF00498 0.480
LIG_FHA_2 903 909 PF00498 0.485
LIG_FHA_2 953 959 PF00498 0.578
LIG_GBD_Chelix_1 199 207 PF00786 0.485
LIG_GBD_Chelix_1 327 335 PF00786 0.491
LIG_GBD_Chelix_1 923 931 PF00786 0.388
LIG_Integrin_isoDGR_2 25 27 PF01839 0.469
LIG_Integrin_RGD_1 106 108 PF01839 0.416
LIG_IRF3_LxIS_1 456 462 PF10401 0.214
LIG_IRF3_LxIS_1 509 516 PF10401 0.233
LIG_LIR_Apic_2 372 376 PF02991 0.360
LIG_LIR_Apic_2 516 522 PF02991 0.339
LIG_LIR_Apic_2 587 591 PF02991 0.440
LIG_LIR_Apic_2 725 731 PF02991 0.447
LIG_LIR_Apic_2 82 88 PF02991 0.416
LIG_LIR_Apic_2 957 962 PF02991 0.471
LIG_LIR_Gen_1 108 117 PF02991 0.394
LIG_LIR_Gen_1 129 139 PF02991 0.429
LIG_LIR_Gen_1 177 186 PF02991 0.334
LIG_LIR_Gen_1 467 476 PF02991 0.374
LIG_LIR_Gen_1 488 496 PF02991 0.362
LIG_LIR_Gen_1 529 538 PF02991 0.427
LIG_LIR_Gen_1 649 658 PF02991 0.293
LIG_LIR_Gen_1 670 676 PF02991 0.327
LIG_LIR_Gen_1 714 723 PF02991 0.261
LIG_LIR_Gen_1 860 871 PF02991 0.482
LIG_LIR_Gen_1 968 978 PF02991 0.536
LIG_LIR_Gen_1 990 1000 PF02991 0.579
LIG_LIR_Nem_3 1026 1032 PF02991 0.495
LIG_LIR_Nem_3 1117 1122 PF02991 0.653
LIG_LIR_Nem_3 129 134 PF02991 0.409
LIG_LIR_Nem_3 141 147 PF02991 0.336
LIG_LIR_Nem_3 467 471 PF02991 0.391
LIG_LIR_Nem_3 488 494 PF02991 0.288
LIG_LIR_Nem_3 52 57 PF02991 0.404
LIG_LIR_Nem_3 529 534 PF02991 0.400
LIG_LIR_Nem_3 541 546 PF02991 0.317
LIG_LIR_Nem_3 642 646 PF02991 0.286
LIG_LIR_Nem_3 649 653 PF02991 0.323
LIG_LIR_Nem_3 654 660 PF02991 0.337
LIG_LIR_Nem_3 670 674 PF02991 0.318
LIG_LIR_Nem_3 686 691 PF02991 0.299
LIG_LIR_Nem_3 714 720 PF02991 0.199
LIG_LIR_Nem_3 766 772 PF02991 0.460
LIG_LIR_Nem_3 860 866 PF02991 0.482
LIG_LIR_Nem_3 870 876 PF02991 0.584
LIG_LIR_Nem_3 942 948 PF02991 0.484
LIG_LIR_Nem_3 968 974 PF02991 0.483
LIG_LIR_Nem_3 990 996 PF02991 0.499
LIG_LIR_Nem_3 997 1003 PF02991 0.460
LIG_LYPXL_yS_3 54 57 PF13949 0.321
LIG_LYPXL_yS_3 688 691 PF13949 0.228
LIG_MYND_3 535 539 PF01753 0.353
LIG_NRBOX 508 514 PF00104 0.239
LIG_NRBOX 708 714 PF00104 0.201
LIG_PCNA_yPIPBox_3 324 334 PF02747 0.417
LIG_PCNA_yPIPBox_3 811 825 PF02747 0.357
LIG_PDZ_Class_3 1317 1322 PF00595 0.634
LIG_Pex14_2 694 698 PF04695 0.263
LIG_Pex14_2 85 89 PF04695 0.421
LIG_PTB_Apo_2 692 699 PF02174 0.232
LIG_SH2_CRK 144 148 PF00017 0.377
LIG_SH2_CRK 162 166 PF00017 0.453
LIG_SH2_CRK 373 377 PF00017 0.362
LIG_SH2_GRB2like 423 426 PF00017 0.321
LIG_SH2_NCK_1 162 166 PF00017 0.465
LIG_SH2_NCK_1 569 573 PF00017 0.467
LIG_SH2_NCK_1 959 963 PF00017 0.452
LIG_SH2_NCK_1 993 997 PF00017 0.572
LIG_SH2_SRC 362 365 PF00017 0.408
LIG_SH2_SRC 959 962 PF00017 0.527
LIG_SH2_SRC 993 996 PF00017 0.572
LIG_SH2_STAP1 232 236 PF00017 0.430
LIG_SH2_STAP1 311 315 PF00017 0.247
LIG_SH2_STAP1 417 421 PF00017 0.367
LIG_SH2_STAP1 494 498 PF00017 0.346
LIG_SH2_STAP1 747 751 PF00017 0.398
LIG_SH2_STAP1 971 975 PF00017 0.537
LIG_SH2_STAT3 389 392 PF00017 0.424
LIG_SH2_STAT3 772 775 PF00017 0.307
LIG_SH2_STAT5 103 106 PF00017 0.320
LIG_SH2_STAT5 1154 1157 PF00017 0.597
LIG_SH2_STAT5 133 136 PF00017 0.309
LIG_SH2_STAT5 216 219 PF00017 0.288
LIG_SH2_STAT5 362 365 PF00017 0.308
LIG_SH2_STAT5 389 392 PF00017 0.383
LIG_SH2_STAT5 423 426 PF00017 0.351
LIG_SH2_STAT5 531 534 PF00017 0.335
LIG_SH2_STAT5 543 546 PF00017 0.273
LIG_SH2_STAT5 569 572 PF00017 0.382
LIG_SH2_STAT5 615 618 PF00017 0.240
LIG_SH3_1 373 379 PF00018 0.261
LIG_SH3_3 1137 1143 PF00018 0.590
LIG_SH3_3 1192 1198 PF00018 0.753
LIG_SH3_3 1293 1299 PF00018 0.511
LIG_SH3_3 373 379 PF00018 0.261
LIG_SH3_3 496 502 PF00018 0.364
LIG_SH3_3 511 517 PF00018 0.335
LIG_SH3_3 57 63 PF00018 0.317
LIG_SH3_3 785 791 PF00018 0.360
LIG_SH3_3 793 799 PF00018 0.354
LIG_SUMO_SIM_anti_2 1292 1297 PF11976 0.535
LIG_SUMO_SIM_anti_2 41 48 PF11976 0.434
LIG_SUMO_SIM_anti_2 495 500 PF11976 0.434
LIG_SUMO_SIM_anti_2 510 516 PF11976 0.272
LIG_SUMO_SIM_anti_2 711 717 PF11976 0.243
LIG_SUMO_SIM_anti_2 828 833 PF11976 0.378
LIG_SUMO_SIM_anti_2 856 865 PF11976 0.483
LIG_SUMO_SIM_par_1 111 118 PF11976 0.251
LIG_SUMO_SIM_par_1 146 153 PF11976 0.276
LIG_SUMO_SIM_par_1 457 464 PF11976 0.380
LIG_SUMO_SIM_par_1 510 516 PF11976 0.280
LIG_SUMO_SIM_par_1 637 642 PF11976 0.380
LIG_SUMO_SIM_par_1 776 781 PF11976 0.299
LIG_SUMO_SIM_par_1 827 833 PF11976 0.421
LIG_TRAF2_1 733 736 PF00917 0.381
LIG_TRAF2_1 967 970 PF00917 0.604
LIG_TRAF2_2 805 810 PF00917 0.326
LIG_TRFH_1 154 158 PF08558 0.272
LIG_TYR_ITIM 544 549 PF00017 0.434
LIG_TYR_ITIM 991 996 PF00017 0.459
LIG_UBA3_1 116 122 PF00899 0.549
LIG_UBA3_1 398 404 PF00899 0.524
LIG_UBA3_1 693 700 PF00899 0.234
LIG_WRC_WIRS_1 151 156 PF05994 0.325
LIG_WRC_WIRS_1 640 645 PF05994 0.311
LIG_WRC_WIRS_1 668 673 PF05994 0.533
LIG_WW_3 1142 1146 PF00397 0.633
MOD_CK1_1 1100 1106 PF00069 0.530
MOD_CK1_1 1178 1184 PF00069 0.477
MOD_CK1_1 1204 1210 PF00069 0.724
MOD_CK1_1 1215 1221 PF00069 0.766
MOD_CK1_1 1257 1263 PF00069 0.759
MOD_CK1_1 149 155 PF00069 0.461
MOD_CK1_1 249 255 PF00069 0.540
MOD_CK1_1 305 311 PF00069 0.659
MOD_CK1_1 547 553 PF00069 0.370
MOD_CK1_1 599 605 PF00069 0.526
MOD_CK1_1 678 684 PF00069 0.515
MOD_CK1_1 794 800 PF00069 0.566
MOD_CK1_1 916 922 PF00069 0.482
MOD_CK2_1 1030 1036 PF00069 0.341
MOD_CK2_1 1072 1078 PF00069 0.672
MOD_CK2_1 1248 1254 PF00069 0.790
MOD_CK2_1 1306 1312 PF00069 0.605
MOD_CK2_1 254 260 PF00069 0.486
MOD_CK2_1 336 342 PF00069 0.416
MOD_CK2_1 554 560 PF00069 0.420
MOD_CK2_1 603 609 PF00069 0.343
MOD_CK2_1 680 686 PF00069 0.339
MOD_CK2_1 730 736 PF00069 0.551
MOD_CK2_1 760 766 PF00069 0.497
MOD_CK2_1 861 867 PF00069 0.330
MOD_CK2_1 964 970 PF00069 0.504
MOD_Cter_Amidation 1066 1069 PF01082 0.518
MOD_Cter_Amidation 1302 1305 PF01082 0.473
MOD_GlcNHglycan 1091 1094 PF01048 0.602
MOD_GlcNHglycan 1183 1186 PF01048 0.611
MOD_GlcNHglycan 1192 1195 PF01048 0.559
MOD_GlcNHglycan 1214 1217 PF01048 0.795
MOD_GlcNHglycan 1222 1225 PF01048 0.759
MOD_GlcNHglycan 1226 1229 PF01048 0.706
MOD_GlcNHglycan 1285 1288 PF01048 0.584
MOD_GlcNHglycan 13 16 PF01048 0.430
MOD_GlcNHglycan 162 165 PF01048 0.475
MOD_GlcNHglycan 18 21 PF01048 0.490
MOD_GlcNHglycan 213 216 PF01048 0.489
MOD_GlcNHglycan 249 252 PF01048 0.537
MOD_GlcNHglycan 307 310 PF01048 0.661
MOD_GlcNHglycan 331 334 PF01048 0.471
MOD_GlcNHglycan 419 422 PF01048 0.437
MOD_GlcNHglycan 467 471 PF01048 0.489
MOD_GlcNHglycan 508 512 PF01048 0.481
MOD_GlcNHglycan 570 573 PF01048 0.478
MOD_GlcNHglycan 576 580 PF01048 0.483
MOD_GlcNHglycan 599 602 PF01048 0.461
MOD_GlcNHglycan 736 739 PF01048 0.561
MOD_GlcNHglycan 762 765 PF01048 0.490
MOD_GlcNHglycan 813 816 PF01048 0.405
MOD_GlcNHglycan 915 918 PF01048 0.425
MOD_GSK3_1 1082 1089 PF00069 0.614
MOD_GSK3_1 1096 1103 PF00069 0.614
MOD_GSK3_1 111 118 PF00069 0.493
MOD_GSK3_1 1143 1150 PF00069 0.618
MOD_GSK3_1 1220 1227 PF00069 0.783
MOD_GSK3_1 1243 1250 PF00069 0.772
MOD_GSK3_1 1268 1275 PF00069 0.792
MOD_GSK3_1 1281 1288 PF00069 0.789
MOD_GSK3_1 146 153 PF00069 0.438
MOD_GSK3_1 16 23 PF00069 0.384
MOD_GSK3_1 160 167 PF00069 0.453
MOD_GSK3_1 205 212 PF00069 0.458
MOD_GSK3_1 246 253 PF00069 0.527
MOD_GSK3_1 301 308 PF00069 0.692
MOD_GSK3_1 34 41 PF00069 0.469
MOD_GSK3_1 434 441 PF00069 0.399
MOD_GSK3_1 472 479 PF00069 0.379
MOD_GSK3_1 503 510 PF00069 0.381
MOD_GSK3_1 544 551 PF00069 0.376
MOD_GSK3_1 596 603 PF00069 0.507
MOD_GSK3_1 604 611 PF00069 0.464
MOD_GSK3_1 68 75 PF00069 0.427
MOD_GSK3_1 680 687 PF00069 0.396
MOD_GSK3_1 730 737 PF00069 0.531
MOD_GSK3_1 752 759 PF00069 0.512
MOD_GSK3_1 791 798 PF00069 0.476
MOD_GSK3_1 857 864 PF00069 0.347
MOD_GSK3_1 902 909 PF00069 0.339
MOD_GSK3_1 960 967 PF00069 0.486
MOD_N-GLC_1 1178 1183 PF02516 0.569
MOD_N-GLC_1 438 443 PF02516 0.477
MOD_N-GLC_1 476 481 PF02516 0.426
MOD_N-GLC_1 492 497 PF02516 0.484
MOD_N-GLC_1 756 761 PF02516 0.489
MOD_NEK2_1 1097 1102 PF00069 0.549
MOD_NEK2_1 1229 1234 PF00069 0.795
MOD_NEK2_1 1243 1248 PF00069 0.819
MOD_NEK2_1 132 137 PF00069 0.477
MOD_NEK2_1 146 151 PF00069 0.430
MOD_NEK2_1 16 21 PF00069 0.376
MOD_NEK2_1 181 186 PF00069 0.382
MOD_NEK2_1 275 280 PF00069 0.531
MOD_NEK2_1 357 362 PF00069 0.269
MOD_NEK2_1 466 471 PF00069 0.439
MOD_NEK2_1 476 481 PF00069 0.398
MOD_NEK2_1 630 635 PF00069 0.488
MOD_NEK2_1 653 658 PF00069 0.377
MOD_NEK2_1 669 674 PF00069 0.273
MOD_NEK2_1 68 73 PF00069 0.495
MOD_NEK2_1 734 739 PF00069 0.418
MOD_NEK2_1 89 94 PF00069 0.462
MOD_NEK2_2 216 221 PF00069 0.260
MOD_PIKK_1 1167 1173 PF00454 0.633
MOD_PIKK_1 476 482 PF00454 0.434
MOD_PK_1 1285 1291 PF00069 0.485
MOD_PKA_1 1236 1242 PF00069 0.759
MOD_PKA_1 1252 1258 PF00069 0.753
MOD_PKA_1 1276 1282 PF00069 0.572
MOD_PKA_1 1306 1312 PF00069 0.543
MOD_PKA_2 1212 1218 PF00069 0.803
MOD_PKA_2 1229 1235 PF00069 0.658
MOD_PKA_2 1236 1242 PF00069 0.784
MOD_PKA_2 126 132 PF00069 0.535
MOD_PKA_2 1276 1282 PF00069 0.820
MOD_PKA_2 1306 1312 PF00069 0.566
MOD_PKA_2 210 216 PF00069 0.484
MOD_PKA_2 348 354 PF00069 0.395
MOD_PKA_2 394 400 PF00069 0.237
MOD_PKA_2 752 758 PF00069 0.561
MOD_PKA_2 964 970 PF00069 0.507
MOD_PKB_1 1145 1153 PF00069 0.675
MOD_PKB_1 1173 1181 PF00069 0.488
MOD_PKB_1 1304 1312 PF00069 0.496
MOD_PKB_1 299 307 PF00069 0.430
MOD_Plk_1 111 117 PF00069 0.236
MOD_Plk_1 281 287 PF00069 0.389
MOD_Plk_1 336 342 PF00069 0.440
MOD_Plk_1 357 363 PF00069 0.414
MOD_Plk_1 466 472 PF00069 0.484
MOD_Plk_1 492 498 PF00069 0.475
MOD_Plk_1 547 553 PF00069 0.495
MOD_Plk_1 575 581 PF00069 0.423
MOD_Plk_2-3 902 908 PF00069 0.330
MOD_Plk_4 111 117 PF00069 0.426
MOD_Plk_4 1201 1207 PF00069 0.755
MOD_Plk_4 1306 1312 PF00069 0.554
MOD_Plk_4 146 152 PF00069 0.474
MOD_Plk_4 281 287 PF00069 0.492
MOD_Plk_4 394 400 PF00069 0.426
MOD_Plk_4 53 59 PF00069 0.507
MOD_Plk_4 608 614 PF00069 0.271
MOD_Plk_4 68 74 PF00069 0.434
MOD_Plk_4 704 710 PF00069 0.345
MOD_Plk_4 711 717 PF00069 0.329
MOD_Plk_4 857 863 PF00069 0.328
MOD_Plk_4 906 912 PF00069 0.344
MOD_ProDKin_1 238 244 PF00069 0.523
MOD_ProDKin_1 375 381 PF00069 0.519
MOD_ProDKin_1 513 519 PF00069 0.392
MOD_ProDKin_1 678 684 PF00069 0.562
MOD_ProDKin_1 702 708 PF00069 0.399
MOD_ProDKin_1 792 798 PF00069 0.453
MOD_SUMO_rev_2 141 147 PF00179 0.394
MOD_SUMO_rev_2 284 293 PF00179 0.554
MOD_SUMO_rev_2 3 8 PF00179 0.292
MOD_SUMO_rev_2 342 351 PF00179 0.455
TRG_DiLeu_BaEn_1 560 565 PF01217 0.489
TRG_DiLeu_BaEn_1 664 669 PF01217 0.208
TRG_DiLeu_BaEn_1 857 862 PF01217 0.460
TRG_DiLeu_BaEn_2 528 534 PF01217 0.407
TRG_DiLeu_BaEn_4 969 975 PF01217 0.364
TRG_DiLeu_BaLyEn_6 1195 1200 PF01217 0.717
TRG_DiLeu_BaLyEn_6 499 504 PF01217 0.508
TRG_DiLeu_BaLyEn_6 833 838 PF01217 0.184
TRG_DiLeu_LyEn_5 1130 1135 PF01217 0.503
TRG_DiLeu_LyEn_5 664 669 PF01217 0.208
TRG_DiLeu_LyEn_5 686 691 PF01217 0.263
TRG_ENDOCYTIC_2 144 147 PF00928 0.495
TRG_ENDOCYTIC_2 231 234 PF00928 0.483
TRG_ENDOCYTIC_2 531 534 PF00928 0.523
TRG_ENDOCYTIC_2 54 57 PF00928 0.547
TRG_ENDOCYTIC_2 546 549 PF00928 0.482
TRG_ENDOCYTIC_2 650 653 PF00928 0.396
TRG_ENDOCYTIC_2 688 691 PF00928 0.502
TRG_ENDOCYTIC_2 945 948 PF00928 0.337
TRG_ENDOCYTIC_2 971 974 PF00928 0.320
TRG_ENDOCYTIC_2 993 996 PF00928 0.457
TRG_ER_diArg_1 1144 1147 PF00400 0.639
TRG_ER_diArg_1 1173 1176 PF00400 0.646
TRG_ER_diArg_1 1235 1237 PF00400 0.686
TRG_ER_diArg_1 124 127 PF00400 0.490
TRG_ER_diArg_1 1276 1278 PF00400 0.822
TRG_ER_diArg_1 1304 1307 PF00400 0.540
TRG_ER_diArg_1 298 301 PF00400 0.420
TRG_ER_diArg_1 803 806 PF00400 0.554
TRG_ER_diArg_1 978 981 PF00400 0.331
TRG_Pf-PMV_PEXEL_1 1276 1280 PF00026 0.511
TRG_Pf-PMV_PEXEL_1 889 893 PF00026 0.405

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 27% 100%
A0A1X0NPQ6 Trypanosomatidae 29% 100%
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 66% 99%
A0A3R7M6J4 Trypanosoma rangeli 36% 100%
A0A3R7R8G4 Trypanosoma rangeli 30% 100%
A0A3S5H6Z8 Leishmania donovani 66% 99%
A0A3S7WU91 Leishmania donovani 98% 93%
A0A3S7WU94 Leishmania donovani 56% 96%
A0A3S7WU95 Leishmania donovani 65% 94%
A0A3S7XB85 Leishmania donovani 28% 94%
A4H8U6 Leishmania braziliensis 56% 100%
A4H8V5 Leishmania braziliensis 68% 100%
A4H8V7 Leishmania braziliensis 60% 100%
A4H8V8 Leishmania braziliensis 59% 100%
A4HPI4 Leishmania braziliensis 27% 100%
A4HX84 Leishmania infantum 56% 100%
A4HX85 Leishmania infantum 67% 100%
A4HX88 Leishmania infantum 52% 100%
A4IDA6 Leishmania infantum 28% 94%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 97%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 59% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 64% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 63% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 56% 100%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 94%
Q25263 Leishmania donovani 65% 99%
Q26721 Trypanosoma brucei brucei 34% 100%
Q27675 Leishmania donovani 56% 96%
Q4Q1A1 Leishmania major 28% 100%
Q4QEH9 Leishmania major 65% 100%
Q4QEI0 Leishmania major 65% 100%
Q4QEI1 Leishmania major 64% 100%
Q4QEI2 Leishmania major 87% 100%
Q4QEI3 Leishmania major 57% 100%
Q99279 Trypanosoma brucei brucei 30% 100%
Q99280 Trypanosoma brucei brucei 32% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS