LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase - putative
Species:
Leishmania infantum
UniProt:
A4HX85_LEIIN
TriTrypDb:
LINF_170007800 *
Length:
1399

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Annotations by Jardim et al.

Receptors, Receptor-type adenylate cyclase b RAC-B2

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) yes yes: 2
Forrest at al. (procyclic) yes yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 57
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 46, no: 27
NetGPI no yes: 0, no: 73
Cellular components
Term Name Level Count
GO:0016020 membrane 2 68
GO:0110165 cellular anatomical entity 1 74

Expansion

Sequence features

A4HX85
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX85

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 74
GO:0006163 purine nucleotide metabolic process 5 74
GO:0006164 purine nucleotide biosynthetic process 6 74
GO:0006171 cAMP biosynthetic process 8 74
GO:0006725 cellular aromatic compound metabolic process 3 74
GO:0006753 nucleoside phosphate metabolic process 4 74
GO:0006793 phosphorus metabolic process 3 74
GO:0006796 phosphate-containing compound metabolic process 4 74
GO:0006807 nitrogen compound metabolic process 2 74
GO:0007165 signal transduction 2 74
GO:0008152 metabolic process 1 74
GO:0009058 biosynthetic process 2 74
GO:0009117 nucleotide metabolic process 5 74
GO:0009150 purine ribonucleotide metabolic process 6 74
GO:0009152 purine ribonucleotide biosynthetic process 7 74
GO:0009165 nucleotide biosynthetic process 6 74
GO:0009187 cyclic nucleotide metabolic process 6 74
GO:0009190 cyclic nucleotide biosynthetic process 7 74
GO:0009259 ribonucleotide metabolic process 5 74
GO:0009260 ribonucleotide biosynthetic process 6 74
GO:0009987 cellular process 1 74
GO:0018130 heterocycle biosynthetic process 4 74
GO:0019438 aromatic compound biosynthetic process 4 74
GO:0019637 organophosphate metabolic process 3 74
GO:0019693 ribose phosphate metabolic process 4 74
GO:0034641 cellular nitrogen compound metabolic process 3 74
GO:0034654 nucleobase-containing compound biosynthetic process 4 74
GO:0035556 intracellular signal transduction 3 74
GO:0044237 cellular metabolic process 2 74
GO:0044238 primary metabolic process 2 74
GO:0044249 cellular biosynthetic process 3 74
GO:0044271 cellular nitrogen compound biosynthetic process 4 74
GO:0044281 small molecule metabolic process 2 74
GO:0046058 cAMP metabolic process 7 74
GO:0046390 ribose phosphate biosynthetic process 5 74
GO:0046483 heterocycle metabolic process 3 74
GO:0050789 regulation of biological process 2 74
GO:0050794 regulation of cellular process 3 74
GO:0052652 cyclic purine nucleotide metabolic process 6 74
GO:0055086 nucleobase-containing small molecule metabolic process 3 74
GO:0065007 biological regulation 1 74
GO:0071704 organic substance metabolic process 2 74
GO:0072521 purine-containing compound metabolic process 4 74
GO:0072522 purine-containing compound biosynthetic process 5 74
GO:0090407 organophosphate biosynthetic process 4 74
GO:1901135 carbohydrate derivative metabolic process 3 74
GO:1901137 carbohydrate derivative biosynthetic process 4 74
GO:1901293 nucleoside phosphate biosynthetic process 5 74
GO:1901360 organic cyclic compound metabolic process 3 74
GO:1901362 organic cyclic compound biosynthetic process 4 74
GO:1901564 organonitrogen compound metabolic process 3 74
GO:1901566 organonitrogen compound biosynthetic process 4 74
GO:1901576 organic substance biosynthetic process 3 74
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 63
GO:0016829 lyase activity 2 63

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 383 387 PF00656 0.550
CLV_C14_Caspase3-7 983 987 PF00656 0.531
CLV_MEL_PAP_1 1056 1062 PF00089 0.322
CLV_NRD_NRD_1 1146 1148 PF00675 0.446
CLV_NRD_NRD_1 1314 1316 PF00675 0.630
CLV_NRD_NRD_1 1353 1355 PF00675 0.676
CLV_NRD_NRD_1 1383 1385 PF00675 0.488
CLV_NRD_NRD_1 207 209 PF00675 0.661
CLV_NRD_NRD_1 660 662 PF00675 0.559
CLV_NRD_NRD_1 801 803 PF00675 0.687
CLV_NRD_NRD_1 9 11 PF00675 0.811
CLV_PCSK_FUR_1 1381 1385 PF00082 0.448
CLV_PCSK_FUR_1 205 209 PF00082 0.656
CLV_PCSK_KEX2_1 1146 1148 PF00082 0.446
CLV_PCSK_KEX2_1 1314 1316 PF00082 0.627
CLV_PCSK_KEX2_1 1353 1355 PF00082 0.506
CLV_PCSK_KEX2_1 1381 1383 PF00082 0.488
CLV_PCSK_KEX2_1 207 209 PF00082 0.662
CLV_PCSK_KEX2_1 801 803 PF00082 0.701
CLV_PCSK_KEX2_1 9 11 PF00082 0.812
CLV_PCSK_SKI1_1 1008 1012 PF00082 0.324
CLV_PCSK_SKI1_1 107 111 PF00082 0.709
CLV_PCSK_SKI1_1 1243 1247 PF00082 0.479
CLV_PCSK_SKI1_1 129 133 PF00082 0.619
CLV_PCSK_SKI1_1 208 212 PF00082 0.634
CLV_PCSK_SKI1_1 283 287 PF00082 0.566
CLV_PCSK_SKI1_1 632 636 PF00082 0.613
CLV_PCSK_SKI1_1 746 750 PF00082 0.553
CLV_PCSK_SKI1_1 768 772 PF00082 0.679
CLV_PCSK_SKI1_1 83 87 PF00082 0.670
CLV_Separin_Metazoa 605 609 PF03568 0.357
DEG_APCC_DBOX_1 599 607 PF00400 0.504
DEG_Nend_Nbox_1 1 3 PF02207 0.787
DEG_SCF_FBW7_2 874 880 PF00400 0.520
DEG_SPOP_SBC_1 289 293 PF00917 0.500
DEG_SPOP_SBC_1 807 811 PF00917 0.532
DOC_CDC14_PxL_1 131 139 PF14671 0.496
DOC_CKS1_1 782 787 PF01111 0.399
DOC_CKS1_1 874 879 PF01111 0.454
DOC_CYCLIN_RxL_1 507 516 PF00134 0.346
DOC_CYCLIN_RxL_1 83 94 PF00134 0.479
DOC_CYCLIN_yCln2_LP_2 236 242 PF00134 0.412
DOC_CYCLIN_yCln2_LP_2 335 341 PF00134 0.360
DOC_CYCLIN_yCln2_LP_2 508 514 PF00134 0.455
DOC_CYCLIN_yCln2_LP_2 871 877 PF00134 0.450
DOC_MAPK_gen_1 205 214 PF00069 0.350
DOC_MAPK_gen_1 30 40 PF00069 0.741
DOC_MAPK_gen_1 83 92 PF00069 0.463
DOC_MAPK_MEF2A_6 186 193 PF00069 0.393
DOC_MAPK_MEF2A_6 33 42 PF00069 0.618
DOC_MAPK_MEF2A_6 510 519 PF00069 0.477
DOC_MAPK_MEF2A_6 714 722 PF00069 0.334
DOC_MAPK_MEF2A_6 83 92 PF00069 0.460
DOC_MAPK_RevD_3 1133 1147 PF00069 0.581
DOC_PP1_RVXF_1 508 515 PF00149 0.342
DOC_PP1_RVXF_1 744 751 PF00149 0.343
DOC_PP2B_LxvP_1 236 239 PF13499 0.374
DOC_PP4_FxxP_1 165 168 PF00568 0.479
DOC_PP4_FxxP_1 825 828 PF00568 0.299
DOC_SPAK_OSR1_1 843 847 PF12202 0.323
DOC_USP7_MATH_1 1245 1249 PF00917 0.708
DOC_USP7_MATH_1 1290 1294 PF00917 0.818
DOC_USP7_MATH_1 1302 1306 PF00917 0.800
DOC_USP7_MATH_1 1349 1353 PF00917 0.698
DOC_USP7_MATH_1 289 293 PF00917 0.498
DOC_USP7_MATH_1 382 386 PF00917 0.435
DOC_USP7_MATH_1 60 64 PF00917 0.490
DOC_USP7_MATH_1 676 680 PF00917 0.497
DOC_USP7_MATH_1 735 739 PF00917 0.479
DOC_USP7_MATH_1 778 782 PF00917 0.477
DOC_USP7_MATH_1 991 995 PF00917 0.602
DOC_WW_Pin1_4 152 157 PF00397 0.441
DOC_WW_Pin1_4 317 322 PF00397 0.469
DOC_WW_Pin1_4 545 550 PF00397 0.511
DOC_WW_Pin1_4 558 563 PF00397 0.471
DOC_WW_Pin1_4 592 597 PF00397 0.390
DOC_WW_Pin1_4 781 786 PF00397 0.399
DOC_WW_Pin1_4 836 841 PF00397 0.410
DOC_WW_Pin1_4 870 875 PF00397 0.420
DOC_WW_Pin1_4 888 893 PF00397 0.504
LIG_14-3-3_CanoR_1 1043 1049 PF00244 0.658
LIG_14-3-3_CanoR_1 1225 1232 PF00244 0.692
LIG_14-3-3_CanoR_1 1243 1248 PF00244 0.664
LIG_14-3-3_CanoR_1 1314 1318 PF00244 0.815
LIG_14-3-3_CanoR_1 1333 1340 PF00244 0.686
LIG_14-3-3_CanoR_1 205 214 PF00244 0.389
LIG_14-3-3_CanoR_1 290 298 PF00244 0.444
LIG_14-3-3_CanoR_1 483 489 PF00244 0.410
LIG_14-3-3_CanoR_1 632 641 PF00244 0.488
LIG_14-3-3_CanoR_1 661 669 PF00244 0.426
LIG_14-3-3_CanoR_1 746 751 PF00244 0.466
LIG_14-3-3_CanoR_1 884 892 PF00244 0.604
LIG_14-3-3_CanoR_1 993 1001 PF00244 0.639
LIG_APCC_ABBA_1 141 146 PF00400 0.476
LIG_APCC_ABBA_1 307 312 PF00400 0.340
LIG_APCC_ABBA_1 719 724 PF00400 0.343
LIG_APCC_ABBA_1 770 775 PF00400 0.282
LIG_BIR_III_2 775 779 PF00653 0.299
LIG_BIR_III_2 927 931 PF00653 0.663
LIG_eIF4E_1 29 35 PF01652 0.688
LIG_FHA_1 1005 1011 PF00498 0.596
LIG_FHA_1 1014 1020 PF00498 0.531
LIG_FHA_1 1039 1045 PF00498 0.540
LIG_FHA_1 1089 1095 PF00498 0.536
LIG_FHA_1 115 121 PF00498 0.418
LIG_FHA_1 1268 1274 PF00498 0.803
LIG_FHA_1 1323 1329 PF00498 0.809
LIG_FHA_1 304 310 PF00498 0.423
LIG_FHA_1 355 361 PF00498 0.492
LIG_FHA_1 44 50 PF00498 0.742
LIG_FHA_1 552 558 PF00498 0.431
LIG_FHA_1 572 578 PF00498 0.390
LIG_FHA_1 655 661 PF00498 0.394
LIG_FHA_1 678 684 PF00498 0.451
LIG_FHA_1 713 719 PF00498 0.464
LIG_FHA_1 811 817 PF00498 0.443
LIG_FHA_1 900 906 PF00498 0.433
LIG_FHA_2 1031 1037 PF00498 0.627
LIG_FHA_2 1151 1157 PF00498 0.766
LIG_FHA_2 1161 1167 PF00498 0.818
LIG_FHA_2 1324 1330 PF00498 0.825
LIG_FHA_2 253 259 PF00498 0.463
LIG_FHA_2 318 324 PF00498 0.467
LIG_FHA_2 416 422 PF00498 0.459
LIG_FHA_2 697 703 PF00498 0.390
LIG_FHA_2 822 828 PF00498 0.357
LIG_FHA_2 837 843 PF00498 0.510
LIG_FHA_2 940 946 PF00498 0.531
LIG_FHA_2 981 987 PF00498 0.535
LIG_GBD_Chelix_1 1001 1009 PF00786 0.441
LIG_GBD_Chelix_1 406 414 PF00786 0.534
LIG_LIR_Apic_2 1035 1040 PF02991 0.520
LIG_LIR_Apic_2 292 298 PF02991 0.296
LIG_LIR_Apic_2 451 455 PF02991 0.413
LIG_LIR_Apic_2 589 594 PF02991 0.400
LIG_LIR_Apic_2 666 672 PF02991 0.503
LIG_LIR_Apic_2 824 828 PF02991 0.395
LIG_LIR_Gen_1 1046 1056 PF02991 0.584
LIG_LIR_Gen_1 1068 1078 PF02991 0.628
LIG_LIR_Gen_1 209 219 PF02991 0.495
LIG_LIR_Gen_1 255 265 PF02991 0.387
LIG_LIR_Gen_1 749 755 PF02991 0.382
LIG_LIR_Gen_1 938 949 PF02991 0.532
LIG_LIR_Nem_3 1020 1026 PF02991 0.533
LIG_LIR_Nem_3 1046 1052 PF02991 0.531
LIG_LIR_Nem_3 1068 1074 PF02991 0.549
LIG_LIR_Nem_3 1075 1081 PF02991 0.510
LIG_LIR_Nem_3 1104 1110 PF02991 0.543
LIG_LIR_Nem_3 1195 1200 PF02991 0.706
LIG_LIR_Nem_3 133 137 PF02991 0.443
LIG_LIR_Nem_3 209 214 PF02991 0.466
LIG_LIR_Nem_3 217 222 PF02991 0.458
LIG_LIR_Nem_3 306 310 PF02991 0.407
LIG_LIR_Nem_3 429 434 PF02991 0.494
LIG_LIR_Nem_3 749 753 PF02991 0.372
LIG_LIR_Nem_3 827 832 PF02991 0.303
LIG_LIR_Nem_3 841 847 PF02991 0.539
LIG_LIR_Nem_3 938 944 PF02991 0.532
LIG_LIR_Nem_3 948 954 PF02991 0.633
LIG_LYPXL_yS_3 134 137 PF13949 0.365
LIG_LYPXL_yS_3 729 732 PF13949 0.471
LIG_MYND_3 614 618 PF01753 0.398
LIG_NRBOX 602 608 PF00104 0.294
LIG_PDZ_Class_3 1394 1399 PF00595 0.670
LIG_Pex14_2 165 169 PF04695 0.469
LIG_Pex14_2 825 829 PF04695 0.486
LIG_PTB_Apo_2 389 396 PF02174 0.343
LIG_PTB_Apo_2 606 613 PF02174 0.343
LIG_PTB_Apo_2 69 76 PF02174 0.395
LIG_PTB_Phospho_1 606 612 PF10480 0.347
LIG_PTB_Phospho_1 69 75 PF10480 0.400
LIG_SH2_CRK 452 456 PF00017 0.414
LIG_SH2_CRK 625 629 PF00017 0.480
LIG_SH2_CRK 669 673 PF00017 0.524
LIG_SH2_GRB2like 390 393 PF00017 0.354
LIG_SH2_GRB2like 669 672 PF00017 0.519
LIG_SH2_GRB2like 847 850 PF00017 0.332
LIG_SH2_NCK_1 1037 1041 PF00017 0.500
LIG_SH2_NCK_1 1071 1075 PF00017 0.621
LIG_SH2_NCK_1 2 6 PF00017 0.481
LIG_SH2_NCK_1 669 673 PF00017 0.360
LIG_SH2_PTP2 295 298 PF00017 0.411
LIG_SH2_PTP2 610 613 PF00017 0.459
LIG_SH2_SRC 1037 1040 PF00017 0.579
LIG_SH2_SRC 1071 1074 PF00017 0.621
LIG_SH2_SRC 2 5 PF00017 0.479
LIG_SH2_SRC 669 672 PF00017 0.512
LIG_SH2_STAP1 1049 1053 PF00017 0.585
LIG_SH2_STAP1 242 246 PF00017 0.471
LIG_SH2_STAP1 311 315 PF00017 0.482
LIG_SH2_STAP1 573 577 PF00017 0.410
LIG_SH2_STAT3 468 471 PF00017 0.477
LIG_SH2_STAT3 850 853 PF00017 0.361
LIG_SH2_STAT5 101 104 PF00017 0.467
LIG_SH2_STAT5 1232 1235 PF00017 0.640
LIG_SH2_STAT5 183 186 PF00017 0.363
LIG_SH2_STAT5 213 216 PF00017 0.370
LIG_SH2_STAT5 295 298 PF00017 0.350
LIG_SH2_STAT5 390 393 PF00017 0.458
LIG_SH2_STAT5 441 444 PF00017 0.356
LIG_SH2_STAT5 468 471 PF00017 0.440
LIG_SH2_STAT5 542 545 PF00017 0.457
LIG_SH2_STAT5 573 576 PF00017 0.494
LIG_SH2_STAT5 591 594 PF00017 0.492
LIG_SH2_STAT5 610 613 PF00017 0.381
LIG_SH2_STAT5 69 72 PF00017 0.438
LIG_SH2_STAT5 918 921 PF00017 0.699
LIG_SH3_3 1215 1221 PF00018 0.638
LIG_SH3_3 1270 1276 PF00018 0.818
LIG_SH3_3 137 143 PF00018 0.352
LIG_SH3_3 1370 1376 PF00018 0.670
LIG_SH3_3 590 596 PF00018 0.399
LIG_SH3_3 863 869 PF00018 0.416
LIG_SH3_3 871 877 PF00018 0.404
LIG_SUMO_SIM_anti_2 121 128 PF11976 0.468
LIG_SUMO_SIM_anti_2 1369 1374 PF11976 0.684
LIG_SUMO_SIM_anti_2 226 233 PF11976 0.330
LIG_SUMO_SIM_anti_2 715 724 PF11976 0.382
LIG_SUMO_SIM_anti_2 906 911 PF11976 0.426
LIG_SUMO_SIM_anti_2 934 943 PF11976 0.535
LIG_SUMO_SIM_par_1 226 233 PF11976 0.330
LIG_SUMO_SIM_par_1 45 51 PF11976 0.688
LIG_SUMO_SIM_par_1 694 699 PF11976 0.432
LIG_SUMO_SIM_par_1 715 724 PF11976 0.438
LIG_SUMO_SIM_par_1 854 859 PF11976 0.353
LIG_TRAF2_1 1045 1048 PF00917 0.653
LIG_TYR_ITIM 1069 1074 PF00017 0.508
LIG_TYR_ITIM 623 628 PF00017 0.472
LIG_TYR_ITIM 727 732 PF00017 0.428
LIG_UBA3_1 193 198 PF00899 0.587
LIG_UBA3_1 621 627 PF00899 0.512
LIG_Vh1_VBS_1 241 259 PF01044 0.350
LIG_WRC_WIRS_1 219 224 PF05994 0.403
LIG_WRC_WIRS_1 297 302 PF05994 0.556
LIG_WRC_WIRS_1 747 752 PF05994 0.589
LIG_WRC_WIRS_1 822 827 PF05994 0.603
LIG_WW_3 1220 1224 PF00397 0.691
MOD_CDK_SPxxK_3 836 843 PF00069 0.437
MOD_CDK_SPxxK_3 888 895 PF00069 0.611
MOD_CK1_1 1178 1184 PF00069 0.588
MOD_CK1_1 1282 1288 PF00069 0.758
MOD_CK1_1 1293 1299 PF00069 0.790
MOD_CK1_1 1324 1330 PF00069 0.785
MOD_CK1_1 245 251 PF00069 0.553
MOD_CK1_1 328 334 PF00069 0.599
MOD_CK1_1 384 390 PF00069 0.649
MOD_CK1_1 492 498 PF00069 0.519
MOD_CK1_1 503 509 PF00069 0.500
MOD_CK1_1 535 541 PF00069 0.467
MOD_CK1_1 636 642 PF00069 0.455
MOD_CK1_1 663 669 PF00069 0.465
MOD_CK1_1 679 685 PF00069 0.561
MOD_CK1_1 757 763 PF00069 0.577
MOD_CK1_1 781 787 PF00069 0.450
MOD_CK1_1 806 812 PF00069 0.547
MOD_CK1_1 821 827 PF00069 0.401
MOD_CK1_1 873 879 PF00069 0.633
MOD_CK1_1 994 1000 PF00069 0.531
MOD_CK2_1 1042 1048 PF00069 0.554
MOD_CK2_1 1108 1114 PF00069 0.391
MOD_CK2_1 1150 1156 PF00069 0.696
MOD_CK2_1 1323 1329 PF00069 0.805
MOD_CK2_1 1383 1389 PF00069 0.618
MOD_CK2_1 223 229 PF00069 0.554
MOD_CK2_1 415 421 PF00069 0.476
MOD_CK2_1 60 66 PF00069 0.728
MOD_CK2_1 821 827 PF00069 0.432
MOD_CK2_1 939 945 PF00069 0.381
MOD_Cter_Amidation 1144 1147 PF01082 0.563
MOD_Cter_Amidation 1379 1382 PF01082 0.532
MOD_GlcNHglycan 1169 1172 PF01048 0.679
MOD_GlcNHglycan 1292 1295 PF01048 0.812
MOD_GlcNHglycan 1300 1303 PF01048 0.798
MOD_GlcNHglycan 1304 1307 PF01048 0.759
MOD_GlcNHglycan 1335 1338 PF01048 0.824
MOD_GlcNHglycan 1362 1365 PF01048 0.672
MOD_GlcNHglycan 160 163 PF01048 0.562
MOD_GlcNHglycan 19 22 PF01048 0.646
MOD_GlcNHglycan 242 245 PF01048 0.524
MOD_GlcNHglycan 292 295 PF01048 0.553
MOD_GlcNHglycan 328 331 PF01048 0.595
MOD_GlcNHglycan 386 389 PF01048 0.641
MOD_GlcNHglycan 410 413 PF01048 0.519
MOD_GlcNHglycan 474 477 PF01048 0.546
MOD_GlcNHglycan 491 494 PF01048 0.528
MOD_GlcNHglycan 628 631 PF01048 0.523
MOD_GlcNHglycan 638 641 PF01048 0.488
MOD_GlcNHglycan 662 665 PF01048 0.556
MOD_GlcNHglycan 684 687 PF01048 0.500
MOD_GlcNHglycan 761 764 PF01048 0.480
MOD_GlcNHglycan 788 791 PF01048 0.476
MOD_GlcNHglycan 93 96 PF01048 0.464
MOD_GlcNHglycan 993 996 PF01048 0.473
MOD_GSK3_1 1038 1045 PF00069 0.536
MOD_GSK3_1 114 121 PF00069 0.485
MOD_GSK3_1 1160 1167 PF00069 0.639
MOD_GSK3_1 1174 1181 PF00069 0.667
MOD_GSK3_1 1221 1228 PF00069 0.665
MOD_GSK3_1 1298 1305 PF00069 0.822
MOD_GSK3_1 1345 1352 PF00069 0.832
MOD_GSK3_1 1358 1365 PF00069 0.829
MOD_GSK3_1 167 174 PF00069 0.426
MOD_GSK3_1 240 247 PF00069 0.511
MOD_GSK3_1 284 291 PF00069 0.515
MOD_GSK3_1 325 332 PF00069 0.580
MOD_GSK3_1 333 340 PF00069 0.578
MOD_GSK3_1 380 387 PF00069 0.684
MOD_GSK3_1 43 50 PF00069 0.725
MOD_GSK3_1 472 479 PF00069 0.583
MOD_GSK3_1 500 507 PF00069 0.521
MOD_GSK3_1 528 535 PF00069 0.460
MOD_GSK3_1 551 558 PF00069 0.462
MOD_GSK3_1 567 574 PF00069 0.495
MOD_GSK3_1 632 639 PF00069 0.504
MOD_GSK3_1 672 679 PF00069 0.521
MOD_GSK3_1 731 738 PF00069 0.560
MOD_GSK3_1 764 771 PF00069 0.481
MOD_GSK3_1 786 793 PF00069 0.524
MOD_GSK3_1 803 810 PF00069 0.565
MOD_GSK3_1 834 841 PF00069 0.610
MOD_GSK3_1 869 876 PF00069 0.528
MOD_GSK3_1 884 891 PF00069 0.637
MOD_GSK3_1 899 906 PF00069 0.399
MOD_GSK3_1 935 942 PF00069 0.398
MOD_GSK3_1 980 987 PF00069 0.389
MOD_N-GLC_1 252 257 PF02516 0.577
MOD_N-GLC_1 426 431 PF02516 0.453
MOD_N-GLC_1 545 550 PF02516 0.539
MOD_N-GLC_1 555 560 PF02516 0.518
MOD_N-GLC_1 571 576 PF02516 0.559
MOD_N-GLC_1 654 659 PF02516 0.511
MOD_NEK2_1 1175 1180 PF00069 0.598
MOD_NEK2_1 1307 1312 PF00069 0.829
MOD_NEK2_1 1321 1326 PF00069 0.827
MOD_NEK2_1 169 174 PF00069 0.516
MOD_NEK2_1 230 235 PF00069 0.557
MOD_NEK2_1 260 265 PF00069 0.426
MOD_NEK2_1 354 359 PF00069 0.580
MOD_NEK2_1 47 52 PF00069 0.586
MOD_NEK2_1 532 537 PF00069 0.488
MOD_NEK2_1 660 665 PF00069 0.427
MOD_NEK2_1 696 701 PF00069 0.525
MOD_NEK2_1 792 797 PF00069 0.441
MOD_NEK2_1 803 808 PF00069 0.534
MOD_NEK2_2 171 176 PF00069 0.522
MOD_PIKK_1 1245 1251 PF00454 0.677
MOD_PIKK_1 399 405 PF00454 0.501
MOD_PIKK_1 434 440 PF00454 0.560
MOD_PIKK_1 494 500 PF00454 0.539
MOD_PIKK_1 778 784 PF00454 0.581
MOD_PK_1 1362 1368 PF00069 0.573
MOD_PK_1 739 745 PF00069 0.390
MOD_PK_1 818 824 PF00069 0.372
MOD_PKA_1 1353 1359 PF00069 0.612
MOD_PKA_1 1383 1389 PF00069 0.586
MOD_PKA_2 1042 1048 PF00069 0.558
MOD_PKA_2 1290 1296 PF00069 0.819
MOD_PKA_2 1307 1313 PF00069 0.726
MOD_PKA_2 1353 1359 PF00069 0.851
MOD_PKA_2 1383 1389 PF00069 0.593
MOD_PKA_2 206 212 PF00069 0.585
MOD_PKA_2 289 295 PF00069 0.549
MOD_PKA_2 29 35 PF00069 0.748
MOD_PKA_2 660 666 PF00069 0.477
MOD_PKB_1 1223 1231 PF00069 0.721
MOD_PKB_1 1381 1389 PF00069 0.540
MOD_PKB_1 882 890 PF00069 0.534
MOD_Plk_1 252 258 PF00069 0.508
MOD_Plk_1 360 366 PF00069 0.432
MOD_Plk_1 426 432 PF00069 0.456
MOD_Plk_1 654 660 PF00069 0.465
MOD_Plk_1 712 718 PF00069 0.550
MOD_Plk_2-3 223 229 PF00069 0.580
MOD_Plk_2-3 980 986 PF00069 0.379
MOD_Plk_4 1279 1285 PF00069 0.796
MOD_Plk_4 133 139 PF00069 0.544
MOD_Plk_4 1383 1389 PF00069 0.586
MOD_Plk_4 223 229 PF00069 0.537
MOD_Plk_4 360 366 PF00069 0.536
MOD_Plk_4 410 416 PF00069 0.569
MOD_Plk_4 513 519 PF00069 0.467
MOD_Plk_4 535 541 PF00069 0.394
MOD_Plk_4 713 719 PF00069 0.539
MOD_Plk_4 728 734 PF00069 0.510
MOD_Plk_4 768 774 PF00069 0.526
MOD_Plk_4 818 824 PF00069 0.384
MOD_Plk_4 903 909 PF00069 0.356
MOD_Plk_4 935 941 PF00069 0.379
MOD_Plk_4 984 990 PF00069 0.393
MOD_ProDKin_1 152 158 PF00069 0.526
MOD_ProDKin_1 317 323 PF00069 0.574
MOD_ProDKin_1 545 551 PF00069 0.625
MOD_ProDKin_1 558 564 PF00069 0.579
MOD_ProDKin_1 592 598 PF00069 0.462
MOD_ProDKin_1 781 787 PF00069 0.472
MOD_ProDKin_1 836 842 PF00069 0.492
MOD_ProDKin_1 870 876 PF00069 0.507
MOD_ProDKin_1 888 894 PF00069 0.618
MOD_SUMO_rev_2 217 227 PF00179 0.473
MOD_SUMO_rev_2 363 372 PF00179 0.596
MOD_SUMO_rev_2 708 716 PF00179 0.608
TRG_DiLeu_BaEn_1 223 228 PF01217 0.595
TRG_DiLeu_BaEn_1 66 71 PF01217 0.557
TRG_DiLeu_BaEn_1 935 940 PF01217 0.509
TRG_DiLeu_BaEn_2 179 185 PF01217 0.586
TRG_DiLeu_BaEn_2 617 623 PF01217 0.388
TRG_DiLeu_BaEn_3 712 718 PF01217 0.594
TRG_DiLeu_BaEn_4 1047 1053 PF01217 0.417
TRG_DiLeu_BaLyEn_6 1273 1278 PF01217 0.785
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.698
TRG_DiLeu_BaLyEn_6 520 525 PF01217 0.565
TRG_DiLeu_LyEn_5 1208 1213 PF01217 0.557
TRG_ENDOCYTIC_2 1023 1026 PF00928 0.387
TRG_ENDOCYTIC_2 1049 1052 PF00928 0.367
TRG_ENDOCYTIC_2 1071 1074 PF00928 0.505
TRG_ENDOCYTIC_2 134 137 PF00928 0.591
TRG_ENDOCYTIC_2 219 222 PF00928 0.579
TRG_ENDOCYTIC_2 310 313 PF00928 0.535
TRG_ENDOCYTIC_2 610 613 PF00928 0.563
TRG_ENDOCYTIC_2 625 628 PF00928 0.515
TRG_ENDOCYTIC_2 729 732 PF00928 0.437
TRG_ENDOCYTIC_2 918 921 PF00928 0.685
TRG_ER_diArg_1 105 108 PF00400 0.603
TRG_ER_diArg_1 1056 1059 PF00400 0.381
TRG_ER_diArg_1 1222 1225 PF00400 0.688
TRG_ER_diArg_1 1313 1315 PF00400 0.688
TRG_ER_diArg_1 1353 1355 PF00400 0.606
TRG_ER_diArg_1 1381 1384 PF00400 0.589
TRG_ER_diArg_1 204 207 PF00400 0.540
TRG_ER_diArg_1 23 26 PF00400 0.673
TRG_ER_diArg_1 8 10 PF00400 0.774
TRG_ER_diArg_1 800 802 PF00400 0.616
TRG_ER_diArg_1 881 884 PF00400 0.598
TRG_Pf-PMV_PEXEL_1 1353 1357 PF00026 0.547
TRG_Pf-PMV_PEXEL_1 225 229 PF00026 0.371
TRG_Pf-PMV_PEXEL_1 801 805 PF00026 0.430
TRG_Pf-PMV_PEXEL_1 967 971 PF00026 0.453

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 100%
A0A1X0P171 Trypanosomatidae 32% 100%
A0A3Q8IJB0 Leishmania donovani 97% 100%
A0A3R7R8G4 Trypanosoma rangeli 30% 100%
A0A3S5H6Z8 Leishmania donovani 97% 100%
A0A3S7WU91 Leishmania donovani 66% 99%
A0A3S7WU94 Leishmania donovani 54% 100%
A0A3S7WU95 Leishmania donovani 91% 100%
A0A3S7XB85 Leishmania donovani 27% 99%
A4H8U6 Leishmania braziliensis 55% 100%
A4H8V5 Leishmania braziliensis 60% 100%
A4H8V7 Leishmania braziliensis 67% 100%
A4H8V8 Leishmania braziliensis 70% 100%
A4HPI4 Leishmania braziliensis 26% 100%
A4HX84 Leishmania infantum 54% 100%
A4HX87 Leishmania infantum 67% 100%
A4IDA6 Leishmania infantum 27% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 63% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
Q25263 Leishmania donovani 99% 100%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 54% 100%
Q4Q1A1 Leishmania major 26% 100%
Q4QEH9 Leishmania major 89% 100%
Q4QEI0 Leishmania major 89% 100%
Q4QEI1 Leishmania major 90% 100%
Q4QEI2 Leishmania major 63% 100%
Q4QEI3 Leishmania major 55% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 32% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS