LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase - putative
Species:
Leishmania infantum
UniProt:
A4HX84_LEIIN
TriTrypDb:
LINF_170007300 *
Length:
1378

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Annotations by Jardim et al.

Receptors, Receptor-type adenylate cyclase a RAC-A

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 51
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 43, no: 27
NetGPI no yes: 0, no: 70
Cellular components
Term Name Level Count
GO:0016020 membrane 2 67
GO:0110165 cellular anatomical entity 1 71

Expansion

Sequence features

A4HX84
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX84

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 71
GO:0006163 purine nucleotide metabolic process 5 71
GO:0006164 purine nucleotide biosynthetic process 6 71
GO:0006171 cAMP biosynthetic process 8 71
GO:0006725 cellular aromatic compound metabolic process 3 71
GO:0006753 nucleoside phosphate metabolic process 4 71
GO:0006793 phosphorus metabolic process 3 71
GO:0006796 phosphate-containing compound metabolic process 4 71
GO:0006807 nitrogen compound metabolic process 2 71
GO:0007165 signal transduction 2 71
GO:0008152 metabolic process 1 71
GO:0009058 biosynthetic process 2 71
GO:0009117 nucleotide metabolic process 5 71
GO:0009150 purine ribonucleotide metabolic process 6 71
GO:0009152 purine ribonucleotide biosynthetic process 7 71
GO:0009165 nucleotide biosynthetic process 6 71
GO:0009187 cyclic nucleotide metabolic process 6 71
GO:0009190 cyclic nucleotide biosynthetic process 7 71
GO:0009259 ribonucleotide metabolic process 5 71
GO:0009260 ribonucleotide biosynthetic process 6 71
GO:0009987 cellular process 1 71
GO:0018130 heterocycle biosynthetic process 4 71
GO:0019438 aromatic compound biosynthetic process 4 71
GO:0019637 organophosphate metabolic process 3 71
GO:0019693 ribose phosphate metabolic process 4 71
GO:0034641 cellular nitrogen compound metabolic process 3 71
GO:0034654 nucleobase-containing compound biosynthetic process 4 71
GO:0035556 intracellular signal transduction 3 71
GO:0044237 cellular metabolic process 2 71
GO:0044238 primary metabolic process 2 71
GO:0044249 cellular biosynthetic process 3 71
GO:0044271 cellular nitrogen compound biosynthetic process 4 71
GO:0044281 small molecule metabolic process 2 71
GO:0046058 cAMP metabolic process 7 71
GO:0046390 ribose phosphate biosynthetic process 5 71
GO:0046483 heterocycle metabolic process 3 71
GO:0050789 regulation of biological process 2 71
GO:0050794 regulation of cellular process 3 71
GO:0052652 cyclic purine nucleotide metabolic process 6 71
GO:0055086 nucleobase-containing small molecule metabolic process 3 71
GO:0065007 biological regulation 1 71
GO:0071704 organic substance metabolic process 2 71
GO:0072521 purine-containing compound metabolic process 4 71
GO:0072522 purine-containing compound biosynthetic process 5 71
GO:0090407 organophosphate biosynthetic process 4 71
GO:1901135 carbohydrate derivative metabolic process 3 71
GO:1901137 carbohydrate derivative biosynthetic process 4 71
GO:1901293 nucleoside phosphate biosynthetic process 5 71
GO:1901360 organic cyclic compound metabolic process 3 71
GO:1901362 organic cyclic compound biosynthetic process 4 71
GO:1901564 organonitrogen compound metabolic process 3 71
GO:1901566 organonitrogen compound biosynthetic process 4 71
GO:1901576 organic substance biosynthetic process 3 71
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 61
GO:0016829 lyase activity 2 61

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1251 1255 PF00656 0.746
CLV_C14_Caspase3-7 1333 1337 PF00656 0.798
CLV_C14_Caspase3-7 172 176 PF00656 0.440
CLV_C14_Caspase3-7 619 623 PF00656 0.239
CLV_C14_Caspase3-7 671 675 PF00656 0.378
CLV_C14_Caspase3-7 833 837 PF00656 0.398
CLV_C14_Caspase3-7 976 980 PF00656 0.480
CLV_MEL_PAP_1 1049 1055 PF00089 0.274
CLV_MEL_PAP_1 1362 1368 PF00089 0.400
CLV_NRD_NRD_1 1139 1141 PF00675 0.472
CLV_NRD_NRD_1 202 204 PF00675 0.609
CLV_NRD_NRD_1 22 24 PF00675 0.712
CLV_NRD_NRD_1 369 371 PF00675 0.602
CLV_NRD_NRD_1 379 381 PF00675 0.546
CLV_PCSK_FUR_1 200 204 PF00082 0.607
CLV_PCSK_KEX2_1 1139 1141 PF00082 0.472
CLV_PCSK_KEX2_1 202 204 PF00082 0.610
CLV_PCSK_KEX2_1 22 24 PF00082 0.735
CLV_PCSK_KEX2_1 307 309 PF00082 0.603
CLV_PCSK_KEX2_1 600 602 PF00082 0.499
CLV_PCSK_PC1ET2_1 307 309 PF00082 0.628
CLV_PCSK_PC1ET2_1 600 602 PF00082 0.555
CLV_PCSK_PC7_1 198 204 PF00082 0.429
CLV_PCSK_SKI1_1 1001 1005 PF00082 0.275
CLV_PCSK_SKI1_1 101 105 PF00082 0.660
CLV_PCSK_SKI1_1 1236 1240 PF00082 0.436
CLV_PCSK_SKI1_1 1303 1307 PF00082 0.397
CLV_PCSK_SKI1_1 1374 1378 PF00082 0.395
CLV_PCSK_SKI1_1 189 193 PF00082 0.538
CLV_PCSK_SKI1_1 203 207 PF00082 0.582
CLV_PCSK_SKI1_1 28 32 PF00082 0.653
CLV_PCSK_SKI1_1 280 284 PF00082 0.507
CLV_PCSK_SKI1_1 300 304 PF00082 0.495
CLV_PCSK_SKI1_1 307 311 PF00082 0.500
CLV_PCSK_SKI1_1 677 681 PF00082 0.517
CLV_PCSK_SKI1_1 803 807 PF00082 0.553
CLV_Separin_Metazoa 1020 1024 PF03568 0.362
DEG_Nend_UBRbox_3 1 3 PF02207 0.700
DEG_SCF_FBW7_2 867 873 PF00400 0.470
DEG_SPOP_SBC_1 285 289 PF00917 0.447
DEG_SPOP_SBC_1 794 798 PF00917 0.473
DOC_CKS1_1 867 872 PF01111 0.405
DOC_CYCLIN_RxL_1 304 314 PF00134 0.263
DOC_CYCLIN_yCln2_LP_2 230 236 PF00134 0.375
DOC_MAPK_FxFP_2 487 490 PF00069 0.283
DOC_MAPK_gen_1 1014 1024 PF00069 0.362
DOC_MAPK_gen_1 198 206 PF00069 0.308
DOC_MAPK_gen_1 26 34 PF00069 0.708
DOC_MAPK_gen_1 539 548 PF00069 0.419
DOC_MAPK_gen_1 597 606 PF00069 0.266
DOC_MAPK_MEF2A_6 181 190 PF00069 0.339
DOC_MAPK_MEF2A_6 542 550 PF00069 0.226
DOC_MAPK_MEF2A_6 683 691 PF00069 0.420
DOC_MAPK_MEF2A_6 705 713 PF00069 0.291
DOC_MAPK_RevD_3 1126 1140 PF00069 0.536
DOC_MAPK_RevD_3 188 203 PF00069 0.254
DOC_PP1_RVXF_1 200 207 PF00149 0.257
DOC_PP1_RVXF_1 298 304 PF00149 0.425
DOC_PP2B_LxvP_1 160 163 PF13499 0.400
DOC_PP4_FxxP_1 487 490 PF00568 0.283
DOC_PP4_FxxP_1 660 663 PF00568 0.435
DOC_PP4_FxxP_1 770 773 PF00568 0.295
DOC_SPAK_OSR1_1 433 437 PF12202 0.250
DOC_USP7_MATH_1 1238 1242 PF00917 0.662
DOC_USP7_MATH_1 1287 1291 PF00917 0.776
DOC_USP7_MATH_1 1293 1297 PF00917 0.745
DOC_USP7_MATH_1 285 289 PF00917 0.445
DOC_USP7_MATH_1 344 348 PF00917 0.348
DOC_USP7_MATH_1 390 394 PF00917 0.288
DOC_USP7_MATH_1 483 487 PF00917 0.405
DOC_USP7_MATH_1 561 565 PF00917 0.330
DOC_USP7_MATH_1 663 667 PF00917 0.418
DOC_USP7_MATH_1 831 835 PF00917 0.424
DOC_USP7_MATH_1 984 988 PF00917 0.552
DOC_WW_Pin1_4 1283 1288 PF00397 0.754
DOC_WW_Pin1_4 326 331 PF00397 0.372
DOC_WW_Pin1_4 678 683 PF00397 0.380
DOC_WW_Pin1_4 774 779 PF00397 0.335
DOC_WW_Pin1_4 863 868 PF00397 0.380
DOC_WW_Pin1_4 881 886 PF00397 0.444
LIG_14-3-3_CanoR_1 1023 1028 PF00244 0.580
LIG_14-3-3_CanoR_1 1036 1042 PF00244 0.606
LIG_14-3-3_CanoR_1 1218 1225 PF00244 0.648
LIG_14-3-3_CanoR_1 1236 1241 PF00244 0.636
LIG_14-3-3_CanoR_1 171 179 PF00244 0.411
LIG_14-3-3_CanoR_1 286 293 PF00244 0.394
LIG_14-3-3_CanoR_1 308 317 PF00244 0.471
LIG_14-3-3_CanoR_1 321 331 PF00244 0.388
LIG_14-3-3_CanoR_1 380 385 PF00244 0.481
LIG_14-3-3_CanoR_1 421 425 PF00244 0.334
LIG_14-3-3_CanoR_1 639 647 PF00244 0.357
LIG_14-3-3_CanoR_1 726 732 PF00244 0.421
LIG_14-3-3_CanoR_1 739 744 PF00244 0.411
LIG_14-3-3_CanoR_1 877 885 PF00244 0.549
LIG_14-3-3_CanoR_1 986 994 PF00244 0.580
LIG_Actin_WH2_2 1230 1248 PF00022 0.469
LIG_Actin_WH2_2 711 728 PF00022 0.386
LIG_AP_GAE_1 250 256 PF02883 0.434
LIG_APCC_ABBA_1 136 141 PF00400 0.420
LIG_APCC_ABBA_1 718 723 PF00400 0.301
LIG_APCC_ABBAyCdc20_2 627 633 PF00400 0.269
LIG_BIR_III_2 920 924 PF00653 0.616
LIG_BRCT_BRCA1_1 175 179 PF00533 0.349
LIG_BRCT_BRCA1_1 352 356 PF00533 0.295
LIG_BRCT_BRCA1_1 543 547 PF00533 0.320
LIG_BRCT_BRCA1_1 695 699 PF00533 0.424
LIG_deltaCOP1_diTrp_1 1301 1305 PF00928 0.583
LIG_deltaCOP1_diTrp_1 757 766 PF00928 0.433
LIG_DLG_GKlike_1 739 746 PF00625 0.241
LIG_eIF4E_1 1016 1022 PF01652 0.362
LIG_FHA_1 1007 1013 PF00498 0.474
LIG_FHA_1 1032 1038 PF00498 0.491
LIG_FHA_1 1082 1088 PF00498 0.483
LIG_FHA_1 143 149 PF00498 0.313
LIG_FHA_1 225 231 PF00498 0.316
LIG_FHA_1 326 332 PF00498 0.283
LIG_FHA_1 34 40 PF00498 0.658
LIG_FHA_1 363 369 PF00498 0.583
LIG_FHA_1 413 419 PF00498 0.408
LIG_FHA_1 632 638 PF00498 0.358
LIG_FHA_1 657 663 PF00498 0.332
LIG_FHA_1 671 677 PF00498 0.391
LIG_FHA_1 726 732 PF00498 0.380
LIG_FHA_1 775 781 PF00498 0.361
LIG_FHA_1 794 800 PF00498 0.345
LIG_FHA_1 804 810 PF00498 0.378
LIG_FHA_1 903 909 PF00498 0.373
LIG_FHA_1 998 1004 PF00498 0.550
LIG_FHA_2 1024 1030 PF00498 0.576
LIG_FHA_2 1144 1150 PF00498 0.715
LIG_FHA_2 1154 1160 PF00498 0.742
LIG_FHA_2 1172 1178 PF00498 0.625
LIG_FHA_2 1246 1252 PF00498 0.710
LIG_FHA_2 170 176 PF00498 0.427
LIG_FHA_2 178 184 PF00498 0.417
LIG_FHA_2 381 387 PF00498 0.361
LIG_FHA_2 624 630 PF00498 0.478
LIG_FHA_2 73 79 PF00498 0.416
LIG_FHA_2 796 802 PF00498 0.348
LIG_FHA_2 82 88 PF00498 0.349
LIG_FHA_2 831 837 PF00498 0.463
LIG_FHA_2 933 939 PF00498 0.480
LIG_FHA_2 974 980 PF00498 0.483
LIG_GBD_Chelix_1 118 126 PF00786 0.615
LIG_GBD_Chelix_1 994 1002 PF00786 0.388
LIG_LIR_Apic_2 1028 1033 PF02991 0.472
LIG_LIR_Apic_2 444 448 PF02991 0.369
LIG_LIR_Apic_2 484 490 PF02991 0.280
LIG_LIR_Apic_2 659 663 PF02991 0.436
LIG_LIR_Gen_1 1018 1027 PF02991 0.459
LIG_LIR_Gen_1 1039 1049 PF02991 0.535
LIG_LIR_Gen_1 1061 1071 PF02991 0.576
LIG_LIR_Gen_1 250 261 PF02991 0.346
LIG_LIR_Gen_1 478 487 PF02991 0.423
LIG_LIR_Gen_1 544 555 PF02991 0.375
LIG_LIR_Gen_1 696 706 PF02991 0.398
LIG_LIR_Gen_1 719 729 PF02991 0.289
LIG_LIR_Gen_1 742 748 PF02991 0.328
LIG_LIR_Gen_1 931 942 PF02991 0.481
LIG_LIR_Nem_3 1013 1019 PF02991 0.482
LIG_LIR_Nem_3 1039 1045 PF02991 0.481
LIG_LIR_Nem_3 1061 1067 PF02991 0.499
LIG_LIR_Nem_3 1068 1074 PF02991 0.459
LIG_LIR_Nem_3 1097 1103 PF02991 0.493
LIG_LIR_Nem_3 1188 1193 PF02991 0.655
LIG_LIR_Nem_3 1301 1305 PF02991 0.609
LIG_LIR_Nem_3 304 309 PF02991 0.384
LIG_LIR_Nem_3 353 359 PF02991 0.395
LIG_LIR_Nem_3 478 482 PF02991 0.346
LIG_LIR_Nem_3 544 550 PF02991 0.401
LIG_LIR_Nem_3 696 702 PF02991 0.376
LIG_LIR_Nem_3 719 725 PF02991 0.316
LIG_LIR_Nem_3 742 746 PF02991 0.320
LIG_LIR_Nem_3 757 763 PF02991 0.334
LIG_LIR_Nem_3 837 843 PF02991 0.452
LIG_LIR_Nem_3 931 937 PF02991 0.481
LIG_LIR_Nem_3 941 947 PF02991 0.582
LIG_LYPXL_yS_3 515 518 PF13949 0.437
LIG_MLH1_MIPbox_1 175 179 PF16413 0.366
LIG_MYND_3 607 611 PF01753 0.352
LIG_NRBOX 225 231 PF00104 0.265
LIG_NRBOX 675 681 PF00104 0.245
LIG_PCNA_yPIPBox_3 128 136 PF02747 0.240
LIG_PCNA_yPIPBox_3 223 231 PF02747 0.257
LIG_PCNA_yPIPBox_3 299 308 PF02747 0.326
LIG_Pex14_2 766 770 PF04695 0.272
LIG_PTB_Apo_2 1366 1373 PF02174 0.577
LIG_PTB_Apo_2 585 592 PF02174 0.332
LIG_PTB_Apo_2 63 70 PF02174 0.355
LIG_PTB_Apo_2 804 811 PF02174 0.273
LIG_PTB_Apo_2 89 96 PF02174 0.242
LIG_PTB_Phospho_1 1366 1372 PF10480 0.579
LIG_PTB_Phospho_1 585 591 PF10480 0.220
LIG_PTB_Phospho_1 63 69 PF10480 0.362
LIG_PTB_Phospho_1 804 810 PF10480 0.314
LIG_PTB_Phospho_1 89 95 PF10480 0.239
LIG_SH2_CRK 237 241 PF00017 0.447
LIG_SH2_CRK 306 310 PF00017 0.434
LIG_SH2_CRK 445 449 PF00017 0.370
LIG_SH2_GRB2like 74 77 PF00017 0.289
LIG_SH2_GRB2like 810 813 PF00017 0.442
LIG_SH2_NCK_1 1030 1034 PF00017 0.450
LIG_SH2_NCK_1 1064 1068 PF00017 0.571
LIG_SH2_NCK_1 116 120 PF00017 0.385
LIG_SH2_NCK_1 237 241 PF00017 0.459
LIG_SH2_NCK_1 591 595 PF00017 0.220
LIG_SH2_NCK_1 618 622 PF00017 0.422
LIG_SH2_PTP2 603 606 PF00017 0.416
LIG_SH2_SRC 1030 1033 PF00017 0.530
LIG_SH2_SRC 1064 1067 PF00017 0.571
LIG_SH2_SRC 116 119 PF00017 0.364
LIG_SH2_SRC 139 142 PF00017 0.236
LIG_SH2_SRC 291 294 PF00017 0.400
LIG_SH2_SRC 810 813 PF00017 0.397
LIG_SH2_STAP1 1042 1046 PF00017 0.536
LIG_SH2_STAP1 1372 1376 PF00017 0.579
LIG_SH2_STAP1 566 570 PF00017 0.349
LIG_SH2_STAP1 69 73 PF00017 0.293
LIG_SH2_STAP1 706 710 PF00017 0.304
LIG_SH2_STAT3 461 464 PF00017 0.427
LIG_SH2_STAT3 641 644 PF00017 0.231
LIG_SH2_STAT5 1225 1228 PF00017 0.596
LIG_SH2_STAT5 139 142 PF00017 0.360
LIG_SH2_STAT5 178 181 PF00017 0.310
LIG_SH2_STAT5 221 224 PF00017 0.375
LIG_SH2_STAT5 237 240 PF00017 0.439
LIG_SH2_STAT5 276 279 PF00017 0.304
LIG_SH2_STAT5 291 294 PF00017 0.298
LIG_SH2_STAT5 349 352 PF00017 0.276
LIG_SH2_STAT5 382 385 PF00017 0.433
LIG_SH2_STAT5 440 443 PF00017 0.317
LIG_SH2_STAT5 461 464 PF00017 0.391
LIG_SH2_STAT5 603 606 PF00017 0.364
LIG_SH2_STAT5 615 618 PF00017 0.271
LIG_SH2_STAT5 63 66 PF00017 0.400
LIG_SH2_STAT5 706 709 PF00017 0.323
LIG_SH2_STAT5 74 77 PF00017 0.350
LIG_SH2_STAT5 810 813 PF00017 0.355
LIG_SH2_STAT5 911 914 PF00017 0.637
LIG_SH3_1 371 377 PF00018 0.377
LIG_SH3_1 445 451 PF00018 0.268
LIG_SH3_3 1208 1214 PF00018 0.590
LIG_SH3_3 1278 1284 PF00018 0.775
LIG_SH3_3 132 138 PF00018 0.303
LIG_SH3_3 29 35 PF00018 0.579
LIG_SH3_3 371 377 PF00018 0.378
LIG_SH3_3 445 451 PF00018 0.268
LIG_SH3_3 583 589 PF00018 0.332
LIG_SH3_3 856 862 PF00018 0.376
LIG_SH3_3 864 870 PF00018 0.330
LIG_SUMO_SIM_anti_2 1357 1365 PF11976 0.668
LIG_SUMO_SIM_anti_2 156 162 PF11976 0.352
LIG_SUMO_SIM_anti_2 468 475 PF11976 0.338
LIG_SUMO_SIM_anti_2 506 512 PF11976 0.338
LIG_SUMO_SIM_anti_2 567 572 PF11976 0.428
LIG_SUMO_SIM_anti_2 707 713 PF11976 0.345
LIG_SUMO_SIM_anti_2 846 852 PF11976 0.239
LIG_SUMO_SIM_anti_2 927 936 PF11976 0.482
LIG_SUMO_SIM_par_1 645 651 PF11976 0.385
LIG_SUMO_SIM_par_1 899 905 PF11976 0.415
LIG_TRAF2_1 1038 1041 PF00917 0.601
LIG_TRAF2_1 127 130 PF00917 0.443
LIG_TRAF2_1 642 645 PF00917 0.259
LIG_TRFH_1 585 589 PF08558 0.239
LIG_TYR_ITIM 1062 1067 PF00017 0.457
LIG_TYR_ITIM 336 341 PF00017 0.488
LIG_TYR_ITIM 616 621 PF00017 0.442
LIG_UBA3_1 122 131 PF00899 0.466
LIG_WRC_WIRS_1 1328 1333 PF05994 0.497
LIG_WRC_WIRS_1 740 745 PF05994 0.531
LIG_WW_3 1213 1217 PF00397 0.636
MOD_CDK_SPK_2 678 683 PF00069 0.274
MOD_CDK_SPxxK_3 881 888 PF00069 0.546
MOD_CK1_1 1171 1177 PF00069 0.560
MOD_CK1_1 1286 1292 PF00069 0.754
MOD_CK1_1 1326 1332 PF00069 0.769
MOD_CK1_1 242 248 PF00069 0.495
MOD_CK1_1 311 317 PF00069 0.518
MOD_CK1_1 325 331 PF00069 0.557
MOD_CK1_1 364 370 PF00069 0.697
MOD_CK1_1 469 475 PF00069 0.499
MOD_CK1_1 496 502 PF00069 0.438
MOD_CK1_1 564 570 PF00069 0.404
MOD_CK1_1 666 672 PF00069 0.466
MOD_CK1_1 742 748 PF00069 0.450
MOD_CK1_1 795 801 PF00069 0.500
MOD_CK1_1 834 840 PF00069 0.417
MOD_CK1_1 865 871 PF00069 0.563
MOD_CK1_1 987 993 PF00069 0.480
MOD_CK2_1 1035 1041 PF00069 0.501
MOD_CK2_1 1101 1107 PF00069 0.340
MOD_CK2_1 1143 1149 PF00069 0.651
MOD_CK2_1 1167 1173 PF00069 0.446
MOD_CK2_1 1295 1301 PF00069 0.627
MOD_CK2_1 1327 1333 PF00069 0.815
MOD_CK2_1 1346 1352 PF00069 0.753
MOD_CK2_1 177 183 PF00069 0.506
MOD_CK2_1 241 247 PF00069 0.341
MOD_CK2_1 380 386 PF00069 0.486
MOD_CK2_1 639 645 PF00069 0.397
MOD_CK2_1 795 801 PF00069 0.505
MOD_CK2_1 843 849 PF00069 0.434
MOD_CK2_1 932 938 PF00069 0.330
MOD_Cter_Amidation 1137 1140 PF01082 0.520
MOD_Cter_Amidation 368 371 PF01082 0.480
MOD_GlcNHglycan 1162 1165 PF01048 0.671
MOD_GlcNHglycan 1273 1276 PF01048 0.765
MOD_GlcNHglycan 1352 1356 PF01048 0.633
MOD_GlcNHglycan 155 158 PF01048 0.514
MOD_GlcNHglycan 167 170 PF01048 0.380
MOD_GlcNHglycan 288 291 PF01048 0.501
MOD_GlcNHglycan 310 313 PF01048 0.548
MOD_GlcNHglycan 324 327 PF01048 0.555
MOD_GlcNHglycan 331 334 PF01048 0.606
MOD_GlcNHglycan 351 355 PF01048 0.383
MOD_GlcNHglycan 403 406 PF01048 0.474
MOD_GlcNHglycan 641 644 PF01048 0.468
MOD_GlcNHglycan 695 698 PF01048 0.343
MOD_GlcNHglycan 751 755 PF01048 0.582
MOD_GlcNHglycan 833 836 PF01048 0.504
MOD_GlcNHglycan 986 989 PF01048 0.425
MOD_GSK3_1 1031 1038 PF00069 0.484
MOD_GSK3_1 1153 1160 PF00069 0.574
MOD_GSK3_1 1167 1174 PF00069 0.619
MOD_GSK3_1 1214 1221 PF00069 0.611
MOD_GSK3_1 1283 1290 PF00069 0.788
MOD_GSK3_1 1309 1316 PF00069 0.760
MOD_GSK3_1 1323 1330 PF00069 0.775
MOD_GSK3_1 142 149 PF00069 0.410
MOD_GSK3_1 165 172 PF00069 0.406
MOD_GSK3_1 173 180 PF00069 0.450
MOD_GSK3_1 235 242 PF00069 0.452
MOD_GSK3_1 280 287 PF00069 0.460
MOD_GSK3_1 322 329 PF00069 0.539
MOD_GSK3_1 376 383 PF00069 0.652
MOD_GSK3_1 408 415 PF00069 0.358
MOD_GSK3_1 465 472 PF00069 0.534
MOD_GSK3_1 489 496 PF00069 0.434
MOD_GSK3_1 666 673 PF00069 0.463
MOD_GSK3_1 68 75 PF00069 0.401
MOD_GSK3_1 727 734 PF00069 0.510
MOD_GSK3_1 795 802 PF00069 0.501
MOD_GSK3_1 814 821 PF00069 0.376
MOD_GSK3_1 827 834 PF00069 0.567
MOD_GSK3_1 862 869 PF00069 0.497
MOD_GSK3_1 877 884 PF00069 0.586
MOD_GSK3_1 928 935 PF00069 0.346
MOD_GSK3_1 973 980 PF00069 0.338
MOD_N-GLC_1 1309 1314 PF02516 0.769
MOD_N-GLC_1 1326 1331 PF02516 0.575
MOD_N-GLC_1 419 424 PF02516 0.405
MOD_N-GLC_1 475 480 PF02516 0.548
MOD_N-GLC_1 494 499 PF02516 0.560
MOD_N-GLC_1 564 569 PF02516 0.487
MOD_N-GLC_1 774 779 PF02516 0.409
MOD_N-GLC_2 536 538 PF02516 0.376
MOD_NEK2_1 1309 1314 PF00069 0.806
MOD_NEK2_1 164 169 PF00069 0.458
MOD_NEK2_1 207 212 PF00069 0.492
MOD_NEK2_1 256 261 PF00069 0.383
MOD_NEK2_1 403 408 PF00069 0.375
MOD_NEK2_1 456 461 PF00069 0.507
MOD_NEK2_1 631 636 PF00069 0.578
MOD_NEK2_1 653 658 PF00069 0.362
MOD_NEK2_1 672 677 PF00069 0.313
MOD_NEK2_1 725 730 PF00069 0.371
MOD_NEK2_1 741 746 PF00069 0.269
MOD_NEK2_1 793 798 PF00069 0.465
MOD_NEK2_1 90 95 PF00069 0.350
MOD_NEK2_1 902 907 PF00069 0.307
MOD_NEK2_2 1295 1300 PF00069 0.465
MOD_NEK2_2 173 178 PF00069 0.484
MOD_NEK2_2 483 488 PF00069 0.466
MOD_PIKK_1 1238 1244 PF00454 0.621
MOD_PIKK_1 1309 1315 PF00454 0.785
MOD_PIKK_1 1318 1324 PF00454 0.528
MOD_PIKK_1 496 502 PF00454 0.445
MOD_PK_1 503 509 PF00069 0.254
MOD_PK_1 542 548 PF00069 0.262
MOD_PKA_1 22 28 PF00069 0.655
MOD_PKA_1 380 386 PF00069 0.601
MOD_PKA_2 1035 1041 PF00069 0.505
MOD_PKA_2 1245 1251 PF00069 0.506
MOD_PKA_2 1323 1329 PF00069 0.780
MOD_PKA_2 1364 1370 PF00069 0.531
MOD_PKA_2 142 148 PF00069 0.486
MOD_PKA_2 207 213 PF00069 0.576
MOD_PKA_2 22 28 PF00069 0.681
MOD_PKA_2 285 291 PF00069 0.499
MOD_PKA_2 3 9 PF00069 0.602
MOD_PKA_2 420 426 PF00069 0.392
MOD_PKA_2 725 731 PF00069 0.305
MOD_PKB_1 1216 1224 PF00069 0.675
MOD_PKB_1 875 883 PF00069 0.487
MOD_Plk_1 1326 1332 PF00069 0.691
MOD_Plk_1 217 223 PF00069 0.322
MOD_Plk_1 242 248 PF00069 0.492
MOD_Plk_1 419 425 PF00069 0.407
MOD_Plk_1 475 481 PF00069 0.514
MOD_Plk_1 483 489 PF00069 0.468
MOD_Plk_1 564 570 PF00069 0.471
MOD_Plk_1 631 637 PF00069 0.483
MOD_Plk_1 716 722 PF00069 0.440
MOD_Plk_2-3 973 979 PF00069 0.328
MOD_Plk_4 173 179 PF00069 0.398
MOD_Plk_4 217 223 PF00069 0.483
MOD_Plk_4 225 231 PF00069 0.488
MOD_Plk_4 293 299 PF00069 0.392
MOD_Plk_4 403 409 PF00069 0.518
MOD_Plk_4 466 472 PF00069 0.431
MOD_Plk_4 503 509 PF00069 0.467
MOD_Plk_4 542 548 PF00069 0.437
MOD_Plk_4 716 722 PF00069 0.460
MOD_Plk_4 776 782 PF00069 0.353
MOD_Plk_4 904 910 PF00069 0.327
MOD_Plk_4 928 934 PF00069 0.328
MOD_Plk_4 977 983 PF00069 0.342
MOD_ProDKin_1 1283 1289 PF00069 0.714
MOD_ProDKin_1 326 332 PF00069 0.465
MOD_ProDKin_1 678 684 PF00069 0.461
MOD_ProDKin_1 774 780 PF00069 0.402
MOD_ProDKin_1 863 869 PF00069 0.471
MOD_ProDKin_1 881 887 PF00069 0.552
MOD_SUMO_rev_2 1250 1257 PF00179 0.694
MOD_SUMO_rev_2 183 191 PF00179 0.499
MOD_SUMO_rev_2 72 82 PF00179 0.343
MOD_SUMO_rev_2 795 805 PF00179 0.540
TRG_DiLeu_BaEn_1 928 933 PF01217 0.457
TRG_DiLeu_BaEn_4 1040 1046 PF01217 0.373
TRG_DiLeu_BaLyEn_6 305 310 PF01217 0.503
TRG_DiLeu_LyEn_5 1201 1206 PF01217 0.515
TRG_ENDOCYTIC_2 1016 1019 PF00928 0.336
TRG_ENDOCYTIC_2 1042 1045 PF00928 0.319
TRG_ENDOCYTIC_2 1064 1067 PF00928 0.455
TRG_ENDOCYTIC_2 306 309 PF00928 0.515
TRG_ENDOCYTIC_2 338 341 PF00928 0.307
TRG_ENDOCYTIC_2 515 518 PF00928 0.477
TRG_ENDOCYTIC_2 603 606 PF00928 0.521
TRG_ENDOCYTIC_2 618 621 PF00928 0.474
TRG_ENDOCYTIC_2 706 709 PF00928 0.390
TRG_ENDOCYTIC_2 722 725 PF00928 0.381
TRG_ENDOCYTIC_2 911 914 PF00928 0.617
TRG_ER_diArg_1 1049 1052 PF00400 0.330
TRG_ER_diArg_1 1215 1218 PF00400 0.635
TRG_ER_diArg_1 1244 1247 PF00400 0.689
TRG_ER_diArg_1 1279 1282 PF00400 0.814
TRG_ER_diArg_1 199 202 PF00400 0.493
TRG_ER_diArg_1 22 24 PF00400 0.693
TRG_ER_diArg_1 624 627 PF00400 0.295
TRG_ER_diArg_1 874 877 PF00400 0.562
TRG_NES_CRM1_1 569 583 PF08389 0.236
TRG_NLS_MonoExtC_3 369 374 PF00514 0.471
TRG_Pf-PMV_PEXEL_1 960 964 PF00026 0.405

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 27% 100%
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 55% 100%
A0A3R7R8G4 Trypanosoma rangeli 30% 100%
A0A3S5H6Z8 Leishmania donovani 56% 100%
A0A3S7WU91 Leishmania donovani 55% 97%
A0A3S7WU94 Leishmania donovani 98% 100%
A0A3S7WU95 Leishmania donovani 54% 98%
A0A3S7XB85 Leishmania donovani 30% 98%
A4H8U6 Leishmania braziliensis 68% 100%
A4H8V5 Leishmania braziliensis 57% 100%
A4H8V7 Leishmania braziliensis 53% 100%
A4H8V8 Leishmania braziliensis 53% 100%
A4HPI4 Leishmania braziliensis 27% 100%
A4HX85 Leishmania infantum 54% 98%
A4HX87 Leishmania infantum 56% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 53% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
Q25263 Leishmania donovani 55% 100%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 99% 100%
Q4QEH9 Leishmania major 55% 100%
Q4QEI0 Leishmania major 55% 100%
Q4QEI1 Leishmania major 56% 100%
Q4QEI2 Leishmania major 56% 100%
Q4QEI3 Leishmania major 86% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 31% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS