B30.2/SPRY domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HX50_LEIIN

TriTrypDb:

LINF_160021300

Length:

1150

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0031298	replication fork protection complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

A4HX50

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX50

Function

Biological processes
Term	Name	Level	Count
GO:0000075	cell cycle checkpoint signaling	4	1
GO:0000076	DNA replication checkpoint signaling	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006275	regulation of DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010564	regulation of cell cycle process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010948	negative regulation of cell cycle process	6	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031570	DNA integrity checkpoint signaling	5	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0035556	intracellular signal transduction	3	1
GO:0043111	replication fork arrest	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	1
GO:0045786	negative regulation of cell cycle	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0050896	response to stimulus	1	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0051726	regulation of cell cycle	4	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901987	regulation of cell cycle phase transition	6	1
GO:1901988	negative regulation of cell cycle phase transition	7	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003677	DNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1038	1042	PF00656	0.694
CLV_C14_Caspase3-7	1105	1109	PF00656	0.569
CLV_C14_Caspase3-7	728	732	PF00656	0.629
CLV_NRD_NRD_1	1025	1027	PF00675	0.597
CLV_NRD_NRD_1	1028	1030	PF00675	0.604
CLV_NRD_NRD_1	1077	1079	PF00675	0.715
CLV_NRD_NRD_1	1089	1091	PF00675	0.807
CLV_NRD_NRD_1	256	258	PF00675	0.520
CLV_NRD_NRD_1	429	431	PF00675	0.635
CLV_NRD_NRD_1	442	444	PF00675	0.452
CLV_NRD_NRD_1	604	606	PF00675	0.339
CLV_NRD_NRD_1	666	668	PF00675	0.424
CLV_NRD_NRD_1	671	673	PF00675	0.331
CLV_PCSK_FUR_1	1023	1027	PF00082	0.596
CLV_PCSK_KEX2_1	1003	1005	PF00082	0.608
CLV_PCSK_KEX2_1	1025	1027	PF00082	0.582
CLV_PCSK_KEX2_1	1028	1030	PF00082	0.587
CLV_PCSK_KEX2_1	1076	1078	PF00082	0.715
CLV_PCSK_KEX2_1	1087	1089	PF00082	0.752
CLV_PCSK_KEX2_1	176	178	PF00082	0.369
CLV_PCSK_KEX2_1	429	431	PF00082	0.651
CLV_PCSK_KEX2_1	444	446	PF00082	0.456
CLV_PCSK_KEX2_1	603	605	PF00082	0.329
CLV_PCSK_KEX2_1	666	668	PF00082	0.399
CLV_PCSK_KEX2_1	7	9	PF00082	0.433
CLV_PCSK_KEX2_1	701	703	PF00082	0.515
CLV_PCSK_KEX2_1	808	810	PF00082	0.537
CLV_PCSK_PC1ET2_1	1003	1005	PF00082	0.608
CLV_PCSK_PC1ET2_1	1076	1078	PF00082	0.715
CLV_PCSK_PC1ET2_1	1087	1089	PF00082	0.752
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.369
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.515
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.433
CLV_PCSK_PC1ET2_1	701	703	PF00082	0.550
CLV_PCSK_PC1ET2_1	808	810	PF00082	0.537
CLV_PCSK_PC7_1	1073	1079	PF00082	0.586
CLV_PCSK_SKI1_1	1029	1033	PF00082	0.621
CLV_PCSK_SKI1_1	1055	1059	PF00082	0.761
CLV_PCSK_SKI1_1	147	151	PF00082	0.421
CLV_PCSK_SKI1_1	447	451	PF00082	0.492
CLV_PCSK_SKI1_1	546	550	PF00082	0.488
CLV_PCSK_SKI1_1	553	557	PF00082	0.524
CLV_PCSK_SKI1_1	594	598	PF00082	0.306
CLV_PCSK_SKI1_1	655	659	PF00082	0.387
CLV_PCSK_SKI1_1	8	12	PF00082	0.379
CLV_PCSK_SKI1_1	808	812	PF00082	0.757
CLV_PCSK_SKI1_1	824	828	PF00082	0.608
CLV_PCSK_SKI1_1	898	902	PF00082	0.368
CLV_PCSK_SKI1_1	965	969	PF00082	0.431
CLV_Separin_Metazoa	741	745	PF03568	0.556
DEG_APCC_DBOX_1	545	553	PF00400	0.417
DEG_APCC_DBOX_1	7	15	PF00400	0.410
DEG_APCC_DBOX_1	823	831	PF00400	0.651
DOC_AGCK_PIF_1	677	682	PF00069	0.408
DOC_CDC14_PxL_1	21	29	PF14671	0.327
DOC_CYCLIN_RxL_1	962	972	PF00134	0.443
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.425
DOC_MAPK_gen_1	560	570	PF00069	0.411
DOC_MAPK_gen_1	600	610	PF00069	0.405
DOC_MAPK_gen_1	7	14	PF00069	0.410
DOC_MAPK_MEF2A_6	104	111	PF00069	0.378
DOC_MAPK_MEF2A_6	127	136	PF00069	0.328
DOC_MAPK_MEF2A_6	184	192	PF00069	0.330
DOC_MAPK_MEF2A_6	217	225	PF00069	0.326
DOC_MAPK_MEF2A_6	264	273	PF00069	0.735
DOC_MAPK_MEF2A_6	603	612	PF00069	0.440
DOC_MAPK_MEF2A_6	7	14	PF00069	0.410
DOC_MAPK_MEF2A_6	934	943	PF00069	0.500
DOC_MAPK_NFAT4_5	7	15	PF00069	0.413
DOC_MAPK_RevD_3	163	177	PF00069	0.334
DOC_PP2B_LxvP_1	105	108	PF13499	0.422
DOC_PP2B_LxvP_1	134	137	PF13499	0.385
DOC_PP2B_LxvP_1	697	700	PF13499	0.501
DOC_PP4_FxxP_1	922	925	PF00568	0.358
DOC_USP7_MATH_1	241	245	PF00917	0.603
DOC_USP7_MATH_1	299	303	PF00917	0.543
DOC_USP7_MATH_1	338	342	PF00917	0.430
DOC_USP7_MATH_1	398	402	PF00917	0.528
DOC_USP7_MATH_1	499	503	PF00917	0.308
DOC_USP7_MATH_1	642	646	PF00917	0.351
DOC_USP7_MATH_1	700	704	PF00917	0.526
DOC_USP7_MATH_1	792	796	PF00917	0.510
DOC_USP7_UBL2_3	383	387	PF12436	0.555
DOC_USP7_UBL2_3	690	694	PF12436	0.424
DOC_USP7_UBL2_3	704	708	PF12436	0.516
DOC_WW_Pin1_4	1016	1021	PF00397	0.611
DOC_WW_Pin1_4	1056	1061	PF00397	0.561
DOC_WW_Pin1_4	361	366	PF00397	0.691
DOC_WW_Pin1_4	454	459	PF00397	0.522
DOC_WW_Pin1_4	522	527	PF00397	0.534
DOC_WW_Pin1_4	844	849	PF00397	0.477
LIG_14-3-3_CanoR_1	138	145	PF00244	0.438
LIG_14-3-3_CanoR_1	367	373	PF00244	0.603
LIG_14-3-3_CanoR_1	407	413	PF00244	0.593
LIG_14-3-3_CanoR_1	809	816	PF00244	0.567
LIG_14-3-3_CanoR_1	934	939	PF00244	0.567
LIG_Actin_WH2_2	535	552	PF00022	0.300
LIG_APCC_ABBAyCdc20_2	277	283	PF00400	0.582
LIG_BIR_II_1	1	5	PF00653	0.413
LIG_BIR_III_4	1103	1107	PF00653	0.535
LIG_BRCT_BRCA1_1	27	31	PF00533	0.384
LIG_BRCT_BRCA1_1	478	482	PF00533	0.438
LIG_BRCT_BRCA1_1	838	842	PF00533	0.469
LIG_BRCT_BRCA1_1	885	889	PF00533	0.476
LIG_Clathr_ClatBox_1	11	15	PF01394	0.408
LIG_deltaCOP1_diTrp_1	325	331	PF00928	0.368
LIG_deltaCOP1_diTrp_1	386	390	PF00928	0.528
LIG_deltaCOP1_diTrp_1	756	764	PF00928	0.574
LIG_EH1_1	218	226	PF00400	0.441
LIG_EH1_1	873	881	PF00400	0.429
LIG_eIF4E_1	614	620	PF01652	0.405
LIG_eIF4E_1	693	699	PF01652	0.443
LIG_FHA_1	1116	1122	PF00498	0.595
LIG_FHA_1	177	183	PF00498	0.522
LIG_FHA_1	196	202	PF00498	0.329
LIG_FHA_1	206	212	PF00498	0.486
LIG_FHA_1	264	270	PF00498	0.704
LIG_FHA_1	47	53	PF00498	0.424
LIG_FHA_1	518	524	PF00498	0.565
LIG_FHA_1	554	560	PF00498	0.380
LIG_FHA_1	679	685	PF00498	0.410
LIG_FHA_1	89	95	PF00498	0.410
LIG_FHA_1	962	968	PF00498	0.474
LIG_FHA_2	1114	1120	PF00498	0.623
LIG_FHA_2	176	182	PF00498	0.480
LIG_FHA_2	204	210	PF00498	0.331
LIG_FHA_2	65	71	PF00498	0.469
LIG_FHA_2	974	980	PF00498	0.482
LIG_IRF3_LxIS_1	14	20	PF10401	0.407
LIG_KLC1_Yacidic_2	974	979	PF13176	0.476
LIG_LIR_Apic_2	341	347	PF02991	0.395
LIG_LIR_Apic_2	921	925	PF02991	0.377
LIG_LIR_Gen_1	1005	1015	PF02991	0.708
LIG_LIR_Gen_1	1092	1099	PF02991	0.525
LIG_LIR_Gen_1	160	171	PF02991	0.329
LIG_LIR_Gen_1	421	428	PF02991	0.536
LIG_LIR_Gen_1	475	485	PF02991	0.353
LIG_LIR_Gen_1	489	498	PF02991	0.352
LIG_LIR_Gen_1	529	539	PF02991	0.400
LIG_LIR_Gen_1	565	571	PF02991	0.609
LIG_LIR_Gen_1	582	593	PF02991	0.344
LIG_LIR_Gen_1	681	688	PF02991	0.414
LIG_LIR_Gen_1	839	848	PF02991	0.474
LIG_LIR_Gen_1	852	863	PF02991	0.460
LIG_LIR_Gen_1	91	101	PF02991	0.392
LIG_LIR_Gen_1	972	983	PF02991	0.427
LIG_LIR_Gen_1	988	994	PF02991	0.525
LIG_LIR_LC3C_4	103	107	PF02991	0.434
LIG_LIR_LC3C_4	222	227	PF02991	0.380
LIG_LIR_LC3C_4	565	569	PF02991	0.365
LIG_LIR_Nem_3	1005	1010	PF02991	0.685
LIG_LIR_Nem_3	1092	1097	PF02991	0.527
LIG_LIR_Nem_3	159	165	PF02991	0.324
LIG_LIR_Nem_3	385	391	PF02991	0.475
LIG_LIR_Nem_3	421	426	PF02991	0.566
LIG_LIR_Nem_3	475	480	PF02991	0.338
LIG_LIR_Nem_3	489	493	PF02991	0.315
LIG_LIR_Nem_3	529	535	PF02991	0.477
LIG_LIR_Nem_3	565	569	PF02991	0.615
LIG_LIR_Nem_3	582	588	PF02991	0.299
LIG_LIR_Nem_3	681	685	PF02991	0.411
LIG_LIR_Nem_3	787	793	PF02991	0.676
LIG_LIR_Nem_3	839	845	PF02991	0.417
LIG_LIR_Nem_3	852	858	PF02991	0.386
LIG_LIR_Nem_3	885	891	PF02991	0.473
LIG_LIR_Nem_3	953	957	PF02991	0.397
LIG_LIR_Nem_3	972	978	PF02991	0.331
LIG_LIR_Nem_3	988	992	PF02991	0.520
LIG_MAD2	917	925	PF02301	0.467
LIG_MLH1_MIPbox_1	838	842	PF16413	0.469
LIG_MLH1_MIPbox_1	885	889	PF16413	0.405
LIG_NRBOX	124	130	PF00104	0.323
LIG_NRBOX	368	374	PF00104	0.592
LIG_NRBOX	621	627	PF00104	0.432
LIG_Pex14_1	760	764	PF04695	0.573
LIG_Pex14_2	566	570	PF04695	0.407
LIG_Pex14_2	889	893	PF04695	0.358
LIG_Pex14_2	923	927	PF04695	0.443
LIG_PTB_Apo_2	226	233	PF02174	0.332
LIG_PTB_Apo_2	887	894	PF02174	0.375
LIG_PTB_Apo_2	921	928	PF02174	0.393
LIG_PTB_Phospho_1	226	232	PF10480	0.325
LIG_REV1ctd_RIR_1	839	847	PF16727	0.413
LIG_SH2_CRK	1094	1098	PF00017	0.527
LIG_SH2_CRK	232	236	PF00017	0.436
LIG_SH2_CRK	532	536	PF00017	0.453
LIG_SH2_CRK	541	545	PF00017	0.405
LIG_SH2_CRK	855	859	PF00017	0.462
LIG_SH2_CRK	989	993	PF00017	0.564
LIG_SH2_GRB2like	532	535	PF00017	0.485
LIG_SH2_GRB2like	74	77	PF00017	0.665
LIG_SH2_NCK_1	1094	1098	PF00017	0.527
LIG_SH2_NCK_1	989	993	PF00017	0.564
LIG_SH2_PTP2	551	554	PF00017	0.359
LIG_SH2_PTP2	585	588	PF00017	0.247
LIG_SH2_STAP1	1094	1098	PF00017	0.527
LIG_SH2_STAP1	664	668	PF00017	0.453
LIG_SH2_STAT5	199	202	PF00017	0.440
LIG_SH2_STAT5	551	554	PF00017	0.376
LIG_SH2_STAT5	585	588	PF00017	0.357
LIG_SH2_STAT5	614	617	PF00017	0.286
LIG_SH2_STAT5	954	957	PF00017	0.513
LIG_SH2_STAT5	975	978	PF00017	0.542
LIG_SH2_STAT5	989	992	PF00017	0.628
LIG_SH3_3	1054	1060	PF00018	0.634
LIG_SH3_3	1129	1135	PF00018	0.617
LIG_SH3_3	520	526	PF00018	0.477
LIG_SH3_3	565	571	PF00018	0.452
LIG_SUMO_SIM_anti_2	185	191	PF11976	0.319
LIG_SUMO_SIM_anti_2	222	228	PF11976	0.434
LIG_SUMO_SIM_anti_2	483	489	PF11976	0.347
LIG_SUMO_SIM_anti_2	617	624	PF11976	0.346
LIG_SUMO_SIM_par_1	10	15	PF11976	0.402
LIG_SUMO_SIM_par_1	185	191	PF11976	0.343
LIG_SUMO_SIM_par_1	192	198	PF11976	0.327
LIG_SUMO_SIM_par_1	483	489	PF11976	0.407
LIG_SUMO_SIM_par_1	519	525	PF11976	0.529
LIG_SUMO_SIM_par_1	578	584	PF11976	0.340
LIG_SUMO_SIM_par_1	617	624	PF11976	0.324
LIG_TRAF2_1	347	350	PF00917	0.485
LIG_TYR_ITIM	539	544	PF00017	0.329
LIG_TYR_ITIM	549	554	PF00017	0.349
LIG_TYR_ITIM	583	588	PF00017	0.374
LIG_TYR_ITIM	853	858	PF00017	0.448
LIG_TYR_ITIM	973	978	PF00017	0.481
LIG_UBA3_1	121	127	PF00899	0.327
LIG_UBA3_1	149	154	PF00899	0.398
LIG_WRC_WIRS_1	477	482	PF05994	0.431
LIG_WRC_WIRS_1	487	492	PF05994	0.369
LIG_WRC_WIRS_1	593	598	PF05994	0.425
LIG_WRC_WIRS_1	679	684	PF05994	0.410
MOD_CDC14_SPxK_1	364	367	PF00782	0.512
MOD_CDK_SPK_2	454	459	PF00069	0.364
MOD_CDK_SPK_2	844	849	PF00069	0.477
MOD_CDK_SPxK_1	361	367	PF00069	0.515
MOD_CDK_SPxxK_3	1016	1023	PF00069	0.602
MOD_CK1_1	1016	1022	PF00069	0.702
MOD_CK1_1	244	250	PF00069	0.583
MOD_CK1_1	26	32	PF00069	0.385
MOD_CK1_1	267	273	PF00069	0.506
MOD_CK1_1	300	306	PF00069	0.566
MOD_CK1_1	361	367	PF00069	0.637
MOD_CK1_1	409	415	PF00069	0.697
MOD_CK1_1	486	492	PF00069	0.430
MOD_CK1_1	517	523	PF00069	0.525
MOD_CK1_1	662	668	PF00069	0.446
MOD_CK1_1	729	735	PF00069	0.680
MOD_CK1_1	767	773	PF00069	0.666
MOD_CK1_1	795	801	PF00069	0.505
MOD_CK1_1	818	824	PF00069	0.575
MOD_CK1_1	828	834	PF00069	0.489
MOD_CK2_1	1044	1050	PF00069	0.672
MOD_CK2_1	1113	1119	PF00069	0.680
MOD_CK2_1	1141	1147	PF00069	0.537
MOD_CK2_1	137	143	PF00069	0.428
MOD_CK2_1	175	181	PF00069	0.430
MOD_CK2_1	203	209	PF00069	0.411
MOD_CK2_1	243	249	PF00069	0.530
MOD_CK2_1	26	32	PF00069	0.422
MOD_CK2_1	64	70	PF00069	0.512
MOD_CK2_1	829	835	PF00069	0.475
MOD_CK2_1	86	92	PF00069	0.565
MOD_CK2_1	973	979	PF00069	0.449
MOD_Cter_Amidation	255	258	PF01082	0.518
MOD_GlcNHglycan	1	4	PF01048	0.588
MOD_GlcNHglycan	1032	1035	PF01048	0.772
MOD_GlcNHglycan	1101	1107	PF01048	0.756
MOD_GlcNHglycan	1110	1113	PF01048	0.672
MOD_GlcNHglycan	139	142	PF01048	0.395
MOD_GlcNHglycan	265	269	PF01048	0.704
MOD_GlcNHglycan	409	412	PF01048	0.654
MOD_GlcNHglycan	474	477	PF01048	0.333
MOD_GlcNHglycan	501	504	PF01048	0.377
MOD_GlcNHglycan	516	519	PF01048	0.435
MOD_GlcNHglycan	577	580	PF01048	0.483
MOD_GlcNHglycan	731	734	PF01048	0.675
MOD_GlcNHglycan	779	782	PF01048	0.696
MOD_GlcNHglycan	795	798	PF01048	0.515
MOD_GlcNHglycan	838	841	PF01048	0.567
MOD_GlcNHglycan	948	951	PF01048	0.502
MOD_GSK3_1	1030	1037	PF00069	0.798
MOD_GSK3_1	1040	1047	PF00069	0.645
MOD_GSK3_1	1102	1109	PF00069	0.678
MOD_GSK3_1	113	120	PF00069	0.301
MOD_GSK3_1	152	159	PF00069	0.550
MOD_GSK3_1	263	270	PF00069	0.617
MOD_GSK3_1	293	300	PF00069	0.579
MOD_GSK3_1	357	364	PF00069	0.575
MOD_GSK3_1	407	414	PF00069	0.733
MOD_GSK3_1	468	475	PF00069	0.559
MOD_GSK3_1	517	524	PF00069	0.485
MOD_GSK3_1	558	565	PF00069	0.483
MOD_GSK3_1	575	582	PF00069	0.270
MOD_GSK3_1	588	595	PF00069	0.292
MOD_GSK3_1	764	771	PF00069	0.668
MOD_GSK3_1	804	811	PF00069	0.636
MOD_GSK3_1	814	821	PF00069	0.546
MOD_GSK3_1	822	829	PF00069	0.455
MOD_GSK3_1	849	856	PF00069	0.456
MOD_GSK3_1	946	953	PF00069	0.569
MOD_GSK3_1	957	964	PF00069	0.441
MOD_GSK3_1	969	976	PF00069	0.477
MOD_LATS_1	262	268	PF00433	0.587
MOD_N-GLC_1	230	235	PF02516	0.427
MOD_N-GLC_1	64	69	PF02516	0.452
MOD_N-GLC_1	726	731	PF02516	0.673
MOD_N-GLC_1	849	854	PF02516	0.452
MOD_N-GLC_1	968	973	PF02516	0.465
MOD_N-GLC_1	997	1002	PF02516	0.614
MOD_NEK2_1	117	122	PF00069	0.371
MOD_NEK2_1	488	493	PF00069	0.337
MOD_NEK2_1	588	593	PF00069	0.406
MOD_NEK2_1	621	626	PF00069	0.326
MOD_NEK2_1	643	648	PF00069	0.316
MOD_NEK2_1	680	685	PF00069	0.316
MOD_NEK2_1	764	769	PF00069	0.772
MOD_NEK2_1	853	858	PF00069	0.356
MOD_NEK2_1	875	880	PF00069	0.314
MOD_NEK2_1	957	962	PF00069	0.435
MOD_NEK2_1	968	973	PF00069	0.458
MOD_NEK2_1	987	992	PF00069	0.475
MOD_NEK2_2	418	423	PF00069	0.564
MOD_PIKK_1	1035	1041	PF00454	0.641
MOD_PIKK_1	809	815	PF00454	0.617
MOD_PK_1	1141	1147	PF00069	0.488
MOD_PK_1	815	821	PF00069	0.680
MOD_PK_1	934	940	PF00069	0.478
MOD_PKA_1	176	182	PF00069	0.406
MOD_PKA_1	382	388	PF00069	0.569
MOD_PKA_1	808	814	PF00069	0.537
MOD_PKA_2	1027	1033	PF00069	0.642
MOD_PKA_2	1106	1112	PF00069	0.546
MOD_PKA_2	137	143	PF00069	0.428
MOD_PKA_2	176	182	PF00069	0.406
MOD_PKA_2	263	269	PF00069	0.523
MOD_PKA_2	300	306	PF00069	0.615
MOD_PKA_2	406	412	PF00069	0.561
MOD_PKA_2	808	814	PF00069	0.694
MOD_PKA_2	961	967	PF00069	0.462
MOD_Plk_1	1005	1011	PF00069	0.718
MOD_Plk_1	230	236	PF00069	0.472
MOD_Plk_1	293	299	PF00069	0.594
MOD_Plk_1	46	52	PF00069	0.498
MOD_Plk_1	606	612	PF00069	0.376
MOD_Plk_1	726	732	PF00069	0.668
MOD_Plk_1	756	762	PF00069	0.566
MOD_Plk_1	764	770	PF00069	0.561
MOD_Plk_1	822	828	PF00069	0.631
MOD_Plk_1	849	855	PF00069	0.422
MOD_Plk_1	957	963	PF00069	0.403
MOD_Plk_1	968	974	PF00069	0.418
MOD_Plk_2-3	726	732	PF00069	0.691
MOD_Plk_2-3	736	742	PF00069	0.665
MOD_Plk_4	117	123	PF00069	0.360
MOD_Plk_4	192	198	PF00069	0.333
MOD_Plk_4	26	32	PF00069	0.388
MOD_Plk_4	338	344	PF00069	0.430
MOD_Plk_4	352	358	PF00069	0.511
MOD_Plk_4	368	374	PF00069	0.579
MOD_Plk_4	418	424	PF00069	0.539
MOD_Plk_4	483	489	PF00069	0.326
MOD_Plk_4	562	568	PF00069	0.490
MOD_Plk_4	621	627	PF00069	0.293
MOD_Plk_4	643	649	PF00069	0.314
MOD_Plk_4	870	876	PF00069	0.411
MOD_Plk_4	883	889	PF00069	0.353
MOD_Plk_4	934	940	PF00069	0.584
MOD_Plk_4	950	956	PF00069	0.322
MOD_Plk_4	973	979	PF00069	0.454
MOD_ProDKin_1	1016	1022	PF00069	0.611
MOD_ProDKin_1	1056	1062	PF00069	0.560
MOD_ProDKin_1	361	367	PF00069	0.689
MOD_ProDKin_1	454	460	PF00069	0.512
MOD_ProDKin_1	522	528	PF00069	0.533
MOD_ProDKin_1	844	850	PF00069	0.471
MOD_SUMO_for_1	1002	1005	PF00179	0.687
MOD_SUMO_for_1	559	562	PF00179	0.453
MOD_SUMO_rev_2	1065	1071	PF00179	0.560
MOD_SUMO_rev_2	501	510	PF00179	0.503
MOD_SUMO_rev_2	595	602	PF00179	0.412
MOD_SUMO_rev_2	770	779	PF00179	0.673
MOD_SUMO_rev_2	974	983	PF00179	0.423
TRG_DiLeu_BaEn_1	161	166	PF01217	0.338
TRG_DiLeu_BaEn_1	617	622	PF01217	0.320
TRG_DiLeu_BaEn_2	561	567	PF01217	0.508
TRG_DiLeu_BaEn_4	349	355	PF01217	0.485
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.326
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.386
TRG_DiLeu_BaLyEn_6	550	555	PF01217	0.258
TRG_ENDOCYTIC_2	1094	1097	PF00928	0.529
TRG_ENDOCYTIC_2	232	235	PF00928	0.424
TRG_ENDOCYTIC_2	453	456	PF00928	0.538
TRG_ENDOCYTIC_2	532	535	PF00928	0.361
TRG_ENDOCYTIC_2	541	544	PF00928	0.264
TRG_ENDOCYTIC_2	551	554	PF00928	0.219
TRG_ENDOCYTIC_2	585	588	PF00928	0.357
TRG_ENDOCYTIC_2	855	858	PF00928	0.455
TRG_ENDOCYTIC_2	920	923	PF00928	0.361
TRG_ENDOCYTIC_2	954	957	PF00928	0.513
TRG_ENDOCYTIC_2	975	978	PF00928	0.418
TRG_ENDOCYTIC_2	989	992	PF00928	0.535
TRG_ER_diArg_1	1023	1026	PF00400	0.597
TRG_ER_diArg_1	1077	1080	PF00400	0.621
TRG_ER_diArg_1	1088	1090	PF00400	0.585
TRG_ER_diArg_1	40	43	PF00400	0.347
TRG_ER_diArg_1	428	430	PF00400	0.650
TRG_ER_diArg_1	442	445	PF00400	0.459
TRG_ER_diArg_1	48	51	PF00400	0.389
TRG_ER_diArg_1	602	605	PF00400	0.336
TRG_ER_diArg_1	666	668	PF00400	0.399
TRG_NES_CRM1_1	9	22	PF08389	0.300
TRG_NLS_Bipartite_1	1076	1091	PF00514	0.717
TRG_NLS_Bipartite_1	429	448	PF00514	0.597
TRG_NLS_MonoCore_2	1086	1091	PF00514	0.707
TRG_NLS_MonoExtC_3	1075	1080	PF00514	0.701
TRG_NLS_MonoExtC_3	1086	1092	PF00514	0.791
TRG_NLS_MonoExtC_3	442	447	PF00514	0.494
TRG_NLS_MonoExtN_4	1073	1080	PF00514	0.709
TRG_NLS_MonoExtN_4	1086	1091	PF00514	0.807
TRG_NLS_MonoExtN_4	443	448	PF00514	0.495
TRG_NLS_MonoExtN_4	700	705	PF00514	0.531
TRG_Pf-PMV_PEXEL_1	308	312	PF00026	0.519
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.360
TRG_Pf-PMV_PEXEL_1	553	557	PF00026	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC20	Leptomonas seymouri	65%	100%
A0A3S7WU73	Leishmania donovani	99%	100%
A0A422N424	Trypanosoma rangeli	41%	100%
A4H8T1	Leishmania braziliensis	75%	100%
C9ZVU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9AQW5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QEL3	Leishmania major	90%	100%
V5BS96	Trypanosoma cruzi	41%	100%