Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HX42_LEIIN

TriTrypDb:

LINF_160020600

Length:

305

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HX42

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX42

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.532
CLV_NRD_NRD_1	106	108	PF00675	0.534
CLV_NRD_NRD_1	142	144	PF00675	0.737
CLV_NRD_NRD_1	157	159	PF00675	0.656
CLV_PCSK_FUR_1	158	162	PF00082	0.573
CLV_PCSK_KEX2_1	102	104	PF00082	0.532
CLV_PCSK_KEX2_1	106	108	PF00082	0.534
CLV_PCSK_KEX2_1	142	144	PF00082	0.703
CLV_PCSK_KEX2_1	157	159	PF00082	0.656
CLV_PCSK_KEX2_1	160	162	PF00082	0.624
CLV_PCSK_KEX2_1	290	292	PF00082	0.544
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.571
CLV_PCSK_PC1ET2_1	290	292	PF00082	0.468
CLV_PCSK_PC7_1	102	108	PF00082	0.485
CLV_PCSK_SKI1_1	157	161	PF00082	0.743
DEG_Nend_UBRbox_3	1	3	PF02207	0.659
DEG_SPOP_SBC_1	219	223	PF00917	0.665
DEG_SPOP_SBC_1	4	8	PF00917	0.560
DOC_MAPK_gen_1	238	247	PF00069	0.605
DOC_MAPK_gen_1	296	304	PF00069	0.519
DOC_MAPK_MEF2A_6	240	249	PF00069	0.601
DOC_USP7_MATH_1	52	56	PF00917	0.432
DOC_USP7_MATH_1	66	70	PF00917	0.498
DOC_USP7_UBL2_3	290	294	PF12436	0.485
DOC_WW_Pin1_4	11	16	PF00397	0.579
DOC_WW_Pin1_4	131	136	PF00397	0.777
DOC_WW_Pin1_4	215	220	PF00397	0.713
LIG_14-3-3_CanoR_1	109	119	PF00244	0.510
LIG_14-3-3_CanoR_1	164	173	PF00244	0.797
LIG_14-3-3_CanoR_1	270	274	PF00244	0.492
LIG_BIR_III_4	187	191	PF00653	0.578
LIG_FHA_1	145	151	PF00498	0.644
LIG_FHA_1	221	227	PF00498	0.690
LIG_FHA_1	277	283	PF00498	0.502
LIG_FHA_1	52	58	PF00498	0.401
LIG_FHA_1	72	78	PF00498	0.425
LIG_FHA_2	163	169	PF00498	0.692
LIG_FHA_2	174	180	PF00498	0.559
LIG_FHA_2	254	260	PF00498	0.495
LIG_FHA_2	57	63	PF00498	0.432
LIG_FHA_2	77	83	PF00498	0.428
LIG_LIR_Gen_1	14	23	PF02991	0.608
LIG_LIR_Gen_1	272	282	PF02991	0.611
LIG_LIR_Nem_3	14	20	PF02991	0.707
LIG_Pex14_2	16	20	PF04695	0.529
LIG_SH2_STAT5	86	89	PF00017	0.402
LIG_SH3_3	132	138	PF00018	0.659
LIG_TRAF2_1	59	62	PF00917	0.510
MOD_CK1_1	167	173	PF00069	0.632
MOD_CK1_1	218	224	PF00069	0.622
MOD_CK1_1	5	11	PF00069	0.717
MOD_CK1_1	69	75	PF00069	0.516
MOD_CK2_1	162	168	PF00069	0.687
MOD_CK2_1	173	179	PF00069	0.588
MOD_CK2_1	253	259	PF00069	0.495
MOD_CK2_1	56	62	PF00069	0.510
MOD_CK2_1	76	82	PF00069	0.428
MOD_Cter_Amidation	100	103	PF01082	0.484
MOD_GlcNHglycan	144	147	PF01048	0.655
MOD_GlcNHglycan	168	172	PF01048	0.688
MOD_GlcNHglycan	191	195	PF01048	0.574
MOD_GSK3_1	144	151	PF00069	0.638
MOD_GSK3_1	160	167	PF00069	0.777
MOD_GSK3_1	2	9	PF00069	0.572
MOD_GSK3_1	215	222	PF00069	0.767
MOD_GSK3_1	52	59	PF00069	0.448
MOD_GSK3_1	67	74	PF00069	0.531
MOD_GSK3_1	76	83	PF00069	0.485
MOD_N-GLC_1	131	136	PF02516	0.688
MOD_NEK2_1	105	110	PF00069	0.503
MOD_NEK2_1	144	149	PF00069	0.649
MOD_NEK2_1	56	61	PF00069	0.439
MOD_NEK2_1	67	72	PF00069	0.522
MOD_PIKK_1	125	131	PF00454	0.727
MOD_PIKK_1	173	179	PF00454	0.679
MOD_PIKK_1	67	73	PF00454	0.470
MOD_PIKK_1	76	82	PF00454	0.403
MOD_PKA_1	142	148	PF00069	0.689
MOD_PKA_1	160	166	PF00069	0.570
MOD_PKA_2	105	111	PF00069	0.486
MOD_PKA_2	142	148	PF00069	0.689
MOD_PKA_2	160	166	PF00069	0.602
MOD_PKA_2	239	245	PF00069	0.432
MOD_PKA_2	269	275	PF00069	0.500
MOD_PKB_1	164	172	PF00069	0.673
MOD_Plk_1	52	58	PF00069	0.435
MOD_Plk_2-3	82	88	PF00069	0.505
MOD_Plk_4	269	275	PF00069	0.500
MOD_Plk_4	52	58	PF00069	0.455
MOD_Plk_4	82	88	PF00069	0.505
MOD_ProDKin_1	11	17	PF00069	0.576
MOD_ProDKin_1	131	137	PF00069	0.778
MOD_ProDKin_1	215	221	PF00069	0.710
MOD_SUMO_for_1	159	162	PF00179	0.652
TRG_ER_diArg_1	105	107	PF00400	0.533
TRG_ER_diArg_1	142	144	PF00400	0.786
TRG_ER_diArg_1	157	159	PF00400	0.756
TRG_Pf-PMV_PEXEL_1	157	162	PF00026	0.653
TRG_Pf-PMV_PEXEL_1	58	62	PF00026	0.512

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HT54	Leptomonas seymouri	33%	94%
A0A3S5H6Z1	Leishmania donovani	100%	100%
E9AQV8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4QEM0	Leishmania major	87%	100%