Putative cytochrome c

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome c - putative

Species:

Leishmania infantum

UniProt:

A4HX28_LEIIN

TriTrypDb:

LINF_160018900

Length:

220

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005758	mitochondrial intermembrane space	6	2
GO:0031970	organelle envelope lumen	5	2
GO:0031974	membrane-enclosed lumen	2	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0070469	respirasome	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HX28

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX28

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0005488	binding	1	2
GO:0009055	electron transfer activity	3	2
GO:0016491	oxidoreductase activity	2	2
GO:0020037	heme binding	4	2
GO:0043167	ion binding	2	2
GO:0043169	cation binding	3	2
GO:0046872	metal ion binding	4	2
GO:0046906	tetrapyrrole binding	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.331
CLV_PCSK_KEX2_1	9	11	PF00082	0.340
CLV_PCSK_SKI1_1	126	130	PF00082	0.199
CLV_Separin_Metazoa	6	10	PF03568	0.345
DEG_Nend_UBRbox_2	1	3	PF02207	0.434
DEG_ODPH_VHL_1	68	80	PF01847	0.372
DOC_CDC14_PxL_1	66	74	PF14671	0.382
DOC_CKS1_1	176	181	PF01111	0.199
DOC_MAPK_gen_1	9	18	PF00069	0.335
DOC_PP2B_LxvP_1	106	109	PF13499	0.414
DOC_PP2B_LxvP_1	67	70	PF13499	0.393
DOC_USP7_MATH_1	25	29	PF00917	0.415
DOC_WW_Pin1_4	175	180	PF00397	0.199
DOC_WW_Pin1_4	23	28	PF00397	0.399
DOC_WW_Pin1_4	29	34	PF00397	0.435
DOC_WW_Pin1_4	61	66	PF00397	0.423
DOC_WW_Pin1_4	86	91	PF00397	0.405
LIG_14-3-3_CanoR_1	9	19	PF00244	0.338
LIG_APCC_ABBA_1	182	187	PF00400	0.199
LIG_BRCT_BRCA1_1	19	23	PF00533	0.362
LIG_CSL_BTD_1	176	179	PF09270	0.199
LIG_FHA_1	102	108	PF00498	0.413
LIG_FHA_1	13	19	PF00498	0.340
LIG_FHA_1	176	182	PF00498	0.199
LIG_FHA_1	38	44	PF00498	0.446
LIG_FHA_1	87	93	PF00498	0.415
LIG_FHA_1	94	100	PF00498	0.406
LIG_KLC1_Yacidic_2	183	187	PF13176	0.199
LIG_LIR_Gen_1	101	110	PF02991	0.407
LIG_LIR_Gen_1	53	61	PF02991	0.441
LIG_LIR_Nem_3	101	106	PF02991	0.415
LIG_LIR_Nem_3	199	203	PF02991	0.199
LIG_LIR_Nem_3	53	59	PF02991	0.443
LIG_SH2_CRK	103	107	PF00017	0.414
LIG_SH2_NCK_1	166	170	PF00017	0.199
LIG_SH2_STAP1	103	107	PF00017	0.414
LIG_SH2_STAT5	103	106	PF00017	0.420
LIG_SH2_STAT5	185	188	PF00017	0.199
LIG_SH2_STAT5	215	218	PF00017	0.199
LIG_SH3_3	112	118	PF00018	0.362
LIG_SH3_3	151	157	PF00018	0.199
LIG_SH3_3	173	179	PF00018	0.199
LIG_SUMO_SIM_par_1	13	20	PF11976	0.342
LIG_SUMO_SIM_par_1	39	46	PF11976	0.447
LIG_SUMO_SIM_par_1	89	96	PF11976	0.417
MOD_CDC14_SPxK_1	32	35	PF00782	0.433
MOD_CDK_SPxK_1	29	35	PF00069	0.434
MOD_CK1_1	17	23	PF00069	0.354
MOD_GlcNHglycan	157	160	PF01048	0.199
MOD_GlcNHglycan	172	175	PF01048	0.199
MOD_GlcNHglycan	27	30	PF01048	0.423
MOD_GSK3_1	10	17	PF00069	0.332
MOD_GSK3_1	23	30	PF00069	0.407
MOD_GSK3_1	42	49	PF00069	0.448
MOD_GSK3_1	55	62	PF00069	0.439
MOD_GSK3_1	70	77	PF00069	0.365
MOD_GSK3_1	82	89	PF00069	0.395
MOD_NEK2_1	12	17	PF00069	0.331
MOD_NEK2_1	164	169	PF00069	0.199
MOD_NEK2_1	42	47	PF00069	0.448
MOD_NEK2_1	59	64	PF00069	0.428
MOD_NEK2_1	92	97	PF00069	0.417
MOD_NEK2_2	215	220	PF00069	0.199
MOD_PIKK_1	10	16	PF00454	0.334
MOD_PIKK_1	59	65	PF00454	0.423
MOD_PIKK_1	70	76	PF00454	0.363
MOD_PIKK_1	93	99	PF00454	0.409
MOD_PKA_1	10	16	PF00069	0.334
MOD_PKA_2	10	16	PF00069	0.334
MOD_PKA_2	155	161	PF00069	0.199
MOD_Plk_4	14	20	PF00069	0.345
MOD_Plk_4	37	43	PF00069	0.443
MOD_ProDKin_1	175	181	PF00069	0.199
MOD_ProDKin_1	23	29	PF00069	0.404
MOD_ProDKin_1	61	67	PF00069	0.420
MOD_ProDKin_1	86	92	PF00069	0.409
TRG_DiLeu_BaLyEn_6	62	67	PF01217	0.416
TRG_DiLeu_BaLyEn_6	88	93	PF01217	0.418
TRG_ENDOCYTIC_2	103	106	PF00928	0.420
TRG_ER_diArg_1	8	11	PF00400	0.342
TRG_Pf-PMV_PEXEL_1	10	14	PF00026	0.330

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A2Y4S9	ORYSI	54%	100%
A8WQY3	CAEBR	54%	100%
A8X769	CAEBR	48%	100%
B4USV4	OTOGA	53%	100%
D5QVH0	METTR	36%	100%
O13393	PICST	50%	100%
O22642	FRIAG	55%	100%
O23138	ARATH	52%	100%
O93863	PACTA	50%	100%
P00002	MACMU	54%	100%
P00003	ATESP	54%	100%
P00004	HORSE	57%	100%
P00007	HIPAM	58%	100%
P00008	RABIT	57%	100%
P00011	CANLF	58%	100%
P00012	MIRLE	58%	100%
P00013	MINSC	57%	100%
P00014	MACGI	58%	100%
P00015	MOUSE	56%	100%
P00017	APTPA	57%	100%
P00018	DRONO	56%	100%
P00019	STRCA	56%	100%
P00020	ANAPL	57%	100%
P00021	COLLI	56%	100%
P00022	CHESE	59%	100%
P00024	LITCT	56%	100%
P00025	KATPE	54%	100%
P00026	CYPCA	57%	100%
P00027	SQUSU	55%	100%
P00028	ENTTR	57%	100%
P00029	ASTRU	57%	100%
P00030	EISFE	57%	100%
P00031	MACMA	55%	100%
P00032	CORAP	48%	100%
P00035	HAEIR	56%	100%
P00036	LUCCU	56%	100%
P00037	SAMCY	55%	100%
P00038	APIME	56%	100%
P00039	MANSE	57%	100%
P00040	SCHGR	56%	100%
P00041	PICKU	50%	100%
P00042	WICAO	51%	100%
P00043	DEBHA	52%	100%
P00044	YEAST	49%	100%
P00045	YEAST	49%	100%
P00046	SCHPO	58%	100%
P00047	THELA	53%	100%
P00048	NEUCR	48%	100%
P00049	USTSP	52%	100%
P00051	CUCMA	54%	100%
P00052	VIGRR	54%	100%
P00053	CANSA	51%	100%
P00054	SESIN	56%	100%
P00056	MAIZE	54%	100%
P00057	RICCO	55%	100%
P00058	GOSBA	54%	100%
P00059	ABUTH	54%	100%
P00060	SOLLC	55%	100%
P00061	SOLTU	55%	100%
P00062	SAMNI	53%	100%
P00063	ACENE	54%	100%
P00064	ALLPO	54%	100%
P00065	ARUMA	53%	100%
P00066	NIGDA	50%	100%
P00067	TROMA	53%	100%
P00068	WHEAT	52%	100%
P00069	GUIAB	52%	100%
P00070	HELAN	53%	100%
P00071	PASSA	52%	100%
P00072	FAGES	55%	100%
P00073	SPIOL	51%	100%
P00074	GINBI	51%	100%
P00075	ULVIN	49%	100%
P00076	EUGGR	59%	100%
P00077	STROO	88%	100%
P00078	CRIFA	88%	100%
P00079	TETPY	40%	100%
P00080	RHOGL	56%	100%
P00081	AGRTC	47%	100%
P00082	RHOVT	48%	100%
P00083	BLAVI	49%	100%
P00084	RHOAC	43%	100%
P00085	NITWI	46%	100%
P00086	MAGFU	44%	100%
P00087	MAGML	44%	100%
P00088	MAGML	45%	100%
P00089	MAGFU	46%	100%
P00090	RHOPL	41%	100%
P00091	RHOPA	40%	100%
P00093	PARPM	36%	100%
P04657	DROME	52%	100%
P0C189	RHORU	41%	100%
P10715	RAT	57%	100%
P12831	SARPE	56%	100%
P12832	NOVIT	44%	100%
P15451	CHLRE	61%	100%
P18822	TRYBB	70%	100%
P19681	SCHOC	52%	100%
P19974	CAEEL	55%	100%
P21665	VARVA	55%	100%
P22342	EUGVI	57%	100%
P23021	STANO	47%	100%
P25400	CANGA	52%	100%
P29380	ARATH	50%	100%
P30323	BRADU	53%	100%
P32556	KLULA	48%	100%
P38091	EMENI	51%	100%
P53698	CANAL	52%	100%
P54820	PARDE	41%	100%
P56205	ASPNG	55%	100%
P59218	ROSNE	53%	100%
P62772	BRANA	54%	100%
P62773	BRAOL	54%	100%
P62894	BOVIN	57%	100%
P62895	PIG	57%	100%
P62896	SHEEP	57%	100%
P62897	MOUSE	57%	100%
P62898	RAT	57%	100%
P67881	CHICK	55%	100%
P67882	MELGA	55%	100%
P68096	EQUQB	57%	100%
P68097	EQUAS	57%	100%
P68098	LAMGU	58%	100%
P68099	CAMDR	58%	100%
P68100	ESCRO	58%	100%
P68517	CROAD	48%	100%
P68518	CROAT	48%	100%
P68519	CROVV	48%	100%
P81153	RHOCE	37%	100%
P81154	RHOCE	36%	100%
P81280	ALLMI	58%	100%
P81459	THUAA	54%	100%
P84029	DROME	57%	100%
P84030	CERCA	57%	100%
P86317	RHOPL	39%	100%
P86318	RHOPL	39%	100%
P86320	RHOAD	32%	100%
P86321	AFIMA	44%	100%
P86322	RHOTP	45%	100%
P86323	RHOTP	45%	100%
P86324	RHOTP	43%	100%
P92504	ASCSU	57%	100%
P92505	ASCSU	48%	100%
P99998	PANTR	54%	100%
P99999	HUMAN	54%	100%
Q00499	PARVE	34%	100%
Q05389	RHOCB	49%	100%
Q0DI31	ORYSJ	54%	100%
Q1KKS2	TAKRU	56%	100%
Q1KL06	TAKRU	55%	100%
Q1RHX7	RICBR	39%	100%
Q23240	CAEEL	50%	100%
Q2RVM4	RHORT	40%	100%
Q3SZT9	BOVIN	52%	100%
Q41346	STELP	50%	100%
Q45233	BRADU	40%	100%
Q4HVX7	GIBZE	53%	100%
Q4N594	THEPA	55%	100%
Q4SG99	TETNG	53%	100%
Q4UEA0	THEAN	56%	100%
Q4UKP6	RICFE	40%	100%
Q52V08	MACSY	54%	100%
Q52V09	CEPBA	56%	100%
Q52V10	SAISC	53%	100%
Q5RFH4	PONAB	54%	100%
Q640U4	XENTR	57%	100%
Q68XB6	RICTY	35%	100%
Q6C9Q0	YARLI	54%	100%
Q6DKE1	XENLA	58%	100%
Q6GQE4	XENLA	55%	100%
Q6IQM2	DANRE	58%	100%
Q6NTN0	XENLA	55%	100%
Q6PBF4	XENTR	56%	100%
Q6Q4H8	PICPA	50%	100%
Q6QLW4	PECGU	55%	100%
Q6WUX8	GORGO	54%	100%
Q753F4	ASHGO	50%	100%
Q7YR71	TRACR	52%	100%
Q869N1	DICDI	53%	100%
Q8UJ37	AGRFC	49%	100%
Q92IT3	RICCN	40%	100%
Q96VP3	COCLU	49%	100%
Q9T0G2	ARATH	53%	100%
Q9ZDS2	RICPR	41%	100%