Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HX12_LEIIN

TriTrypDb:

LINF_160017300

Length:

242


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4HX12

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HX12


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	103	105	PF00675	0.295
CLV_NRD_NRD_1	184	186	PF00675	0.593
CLV_NRD_NRD_1	75	77	PF00675	0.379
CLV_NRD_NRD_1	86	88	PF00675	0.401
CLV_PCSK_KEX2_1	102	104	PF00082	0.383
CLV_PCSK_KEX2_1	184	186	PF00082	0.526
CLV_PCSK_KEX2_1	75	77	PF00082	0.379
CLV_PCSK_SKI1_1	27	31	PF00082	0.528
DEG_Nend_Nbox_1	1	3	PF02207	0.438
DOC_CYCLIN_RxL_1	73	83	PF00134	0.487
DOC_PP1_RVXF_1	74	81	PF00149	0.382
LIG_14-3-3_CanoR_1	75	79	PF00244	0.537
LIG_BRCT_BRCA1_1	76	80	PF00533	0.442
LIG_deltaCOP1_diTrp_1	46	53	PF00928	0.455
LIG_FHA_1	39	45	PF00498	0.526
LIG_LIR_Gen_1	58	67	PF02991	0.379
LIG_LIR_Nem_3	58	62	PF02991	0.366
LIG_PCNA_yPIPBox_3	12	22	PF02747	0.475
LIG_SH2_STAT5	127	130	PF00017	0.442
LIG_SH2_STAT5	226	229	PF00017	0.499
LIG_SUMO_SIM_anti_2	41	48	PF11976	0.371
LIG_SUMO_SIM_par_1	40	48	PF11976	0.378
LIG_TRAF2_1	230	233	PF00917	0.455
LIG_TRFH_1	186	190	PF08558	0.457
MOD_CK2_1	40	46	PF00069	0.386
MOD_GlcNHglycan	228	231	PF01048	0.567
MOD_GSK3_1	222	229	PF00069	0.434
MOD_NEK2_1	202	207	PF00069	0.560
MOD_PIKK_1	107	113	PF00454	0.556
MOD_PKA_2	107	113	PF00069	0.466
MOD_PKA_2	74	80	PF00069	0.444
MOD_Plk_1	25	31	PF00069	0.639
MOD_Plk_4	159	165	PF00069	0.436
MOD_Plk_4	25	31	PF00069	0.572
MOD_Plk_4	40	46	PF00069	0.521
MOD_SUMO_for_1	179	182	PF00179	0.398
TRG_DiLeu_BaEn_1	14	19	PF01217	0.415
TRG_DiLeu_BaEn_3	16	22	PF01217	0.547
TRG_ENDOCYTIC_2	136	139	PF00928	0.398
TRG_ENDOCYTIC_2	59	62	PF00928	0.455
TRG_ER_diArg_1	102	104	PF00400	0.320
TRG_ER_diArg_1	184	186	PF00400	0.452
TRG_ER_diArg_1	84	87	PF00400	0.455
TRG_Pf-PMV_PEXEL_1	133	137	PF00026	0.312
TRG_Pf-PMV_PEXEL_1	4	8	PF00026	0.475


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Q2	Leptomonas seymouri	52%	68%
A0A1X0P6N1	Trypanosomatidae	39%	71%
A0A3S7WU27	Leishmania donovani	100%	100%
A0A422NPU4	Trypanosoma rangeli	38%	70%
A4H8P2	Leishmania braziliensis	71%	100%
D0A000	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	71%
E9AQS6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QEQ2	Leishmania major	94%	100%
V5C1M6	Trypanosoma cruzi	38%	72%