LeishMANIAdb
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Polysacc_synt_4 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Polysacc_synt_4 domain-containing protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HWX8_LEIIN
TriTrypDb:
LINF_160013600
Length:
601

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4HWX8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HWX8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 205 209 PF00656 0.555
CLV_C14_Caspase3-7 411 415 PF00656 0.324
CLV_MEL_PAP_1 312 318 PF00089 0.698
CLV_NRD_NRD_1 127 129 PF00675 0.616
CLV_NRD_NRD_1 15 17 PF00675 0.438
CLV_NRD_NRD_1 291 293 PF00675 0.522
CLV_NRD_NRD_1 314 316 PF00675 0.705
CLV_NRD_NRD_1 386 388 PF00675 0.576
CLV_NRD_NRD_1 433 435 PF00675 0.624
CLV_NRD_NRD_1 570 572 PF00675 0.418
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P6R7 Leptomonas seymouri 65% 100%
A0A0S4IJV1 Bodo saltans 37% 100%
A0A1X0NZ16 Trypanosomatidae 45% 100%
A0A3Q8IJ17 Leishmania donovani 100% 100%
A4H8K5 Leishmania braziliensis 82% 100%
C9ZW26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 46% 100%
E9AQP0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4QET8 Leishmania major 96% 100%
V5D930 Trypanosoma cruzi 46% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS