Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

LysM domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4HWW7_LEIIN

TriTrypDb:

LINF_160012400

Length:

849

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HWW7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HWW7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	427	431	PF00656	0.657
CLV_NRD_NRD_1	185	187	PF00675	0.626
CLV_NRD_NRD_1	440	442	PF00675	0.643
CLV_NRD_NRD_1	692	694	PF00675	0.688
CLV_NRD_NRD_1	819	821	PF00675	0.637
CLV_PCSK_KEX2_1	185	187	PF00082	0.637
CLV_PCSK_KEX2_1	439	441	PF00082	0.646
CLV_PCSK_KEX2_1	5	7	PF00082	0.521
CLV_PCSK_KEX2_1	692	694	PF00082	0.688
CLV_PCSK_KEX2_1	819	821	PF00082	0.564
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.478
CLV_PCSK_PC7_1	436	442	PF00082	0.645
CLV_PCSK_SKI1_1	455	459	PF00082	0.637
CLV_PCSK_SKI1_1	685	689	PF00082	0.644
CLV_Separin_Metazoa	514	518	PF03568	0.587
CLV_Separin_Metazoa	629	633	PF03568	0.533
CLV_Separin_Metazoa	816	820	PF03568	0.606
DEG_APCC_DBOX_1	283	291	PF00400	0.646
DEG_COP1_1	242	251	PF00400	0.627
DEG_COP1_1	320	330	PF00400	0.575
DEG_Nend_UBRbox_2	1	3	PF02207	0.533
DEG_SCF_TRCP1_1	237	243	PF00400	0.686
DEG_SPOP_SBC_1	139	143	PF00917	0.642
DEG_SPOP_SBC_1	190	194	PF00917	0.687
DEG_SPOP_SBC_1	596	600	PF00917	0.687
DOC_CKS1_1	577	582	PF01111	0.684
DOC_MAPK_DCC_7	244	253	PF00069	0.625
DOC_MAPK_MEF2A_6	103	111	PF00069	0.267
DOC_MAPK_MEF2A_6	244	253	PF00069	0.625
DOC_MAPK_MEF2A_6	702	709	PF00069	0.631
DOC_PP2B_LxvP_1	251	254	PF13499	0.630
DOC_PP2B_LxvP_1	330	333	PF13499	0.612
DOC_PP2B_LxvP_1	464	467	PF13499	0.590
DOC_PP2B_LxvP_1	537	540	PF13499	0.635
DOC_PP2B_LxvP_1	718	721	PF13499	0.642
DOC_PP2B_LxvP_1	724	727	PF13499	0.581
DOC_PP4_FxxP_1	577	580	PF00568	0.684
DOC_PP4_FxxP_1	687	690	PF00568	0.642
DOC_PP4_MxPP_1	410	413	PF00568	0.600
DOC_PP4_MxPP_1	649	652	PF00568	0.697
DOC_USP7_MATH_1	137	141	PF00917	0.675
DOC_USP7_MATH_1	190	194	PF00917	0.687
DOC_USP7_MATH_1	206	210	PF00917	0.508
DOC_USP7_MATH_1	219	223	PF00917	0.559
DOC_USP7_MATH_1	311	315	PF00917	0.645
DOC_USP7_MATH_1	318	322	PF00917	0.578
DOC_USP7_MATH_1	326	330	PF00917	0.550
DOC_USP7_MATH_1	393	397	PF00917	0.620
DOC_USP7_MATH_1	413	417	PF00917	0.521
DOC_USP7_MATH_1	447	451	PF00917	0.611
DOC_USP7_MATH_1	538	542	PF00917	0.655
DOC_USP7_MATH_1	565	569	PF00917	0.657
DOC_USP7_MATH_1	596	600	PF00917	0.650
DOC_USP7_MATH_1	610	614	PF00917	0.582
DOC_USP7_MATH_1	625	629	PF00917	0.560
DOC_USP7_MATH_1	694	698	PF00917	0.567
DOC_USP7_MATH_1	719	723	PF00917	0.614
DOC_USP7_MATH_1	794	798	PF00917	0.578
DOC_USP7_MATH_2	34	40	PF00917	0.569
DOC_WW_Pin1_4	129	134	PF00397	0.600
DOC_WW_Pin1_4	141	146	PF00397	0.566
DOC_WW_Pin1_4	242	247	PF00397	0.696
DOC_WW_Pin1_4	277	282	PF00397	0.628
DOC_WW_Pin1_4	295	300	PF00397	0.634
DOC_WW_Pin1_4	319	324	PF00397	0.645
DOC_WW_Pin1_4	348	353	PF00397	0.694
DOC_WW_Pin1_4	381	386	PF00397	0.657
DOC_WW_Pin1_4	465	470	PF00397	0.647
DOC_WW_Pin1_4	478	483	PF00397	0.566
DOC_WW_Pin1_4	519	524	PF00397	0.692
DOC_WW_Pin1_4	531	536	PF00397	0.586
DOC_WW_Pin1_4	544	549	PF00397	0.570
DOC_WW_Pin1_4	570	575	PF00397	0.637
DOC_WW_Pin1_4	576	581	PF00397	0.641
DOC_WW_Pin1_4	605	610	PF00397	0.684
DOC_WW_Pin1_4	643	648	PF00397	0.542
DOC_WW_Pin1_4	658	663	PF00397	0.530
DOC_WW_Pin1_4	709	714	PF00397	0.593
DOC_WW_Pin1_4	826	831	PF00397	0.686
DOC_WW_Pin1_4	839	844	PF00397	0.549
LIG_14-3-3_CanoR_1	138	145	PF00244	0.637
LIG_14-3-3_CanoR_1	312	318	PF00244	0.704
LIG_14-3-3_CanoR_1	403	410	PF00244	0.675
LIG_14-3-3_CanoR_1	423	429	PF00244	0.530
LIG_14-3-3_CanoR_1	47	54	PF00244	0.519
LIG_14-3-3_CanoR_1	491	499	PF00244	0.658
LIG_14-3-3_CanoR_1	527	537	PF00244	0.602
LIG_14-3-3_CanoR_1	678	683	PF00244	0.623
LIG_14-3-3_CanoR_1	685	690	PF00244	0.593
LIG_BIR_III_2	710	714	PF00653	0.589
LIG_BRCT_BRCA1_1	214	218	PF00533	0.610
LIG_BRCT_BRCA1_1	612	616	PF00533	0.568
LIG_CtBP_PxDLS_1	663	667	PF00389	0.664
LIG_CtBP_PxDLS_1	715	719	PF00389	0.644
LIG_EVH1_2	332	336	PF00568	0.580
LIG_EVH1_2	683	687	PF00568	0.616
LIG_FHA_2	30	36	PF00498	0.711
LIG_FHA_2	766	772	PF00498	0.342
LIG_IBAR_NPY_1	773	775	PF08397	0.385
LIG_LIR_Apic_2	575	580	PF02991	0.678
LIG_LIR_Gen_1	122	131	PF02991	0.385
LIG_LIR_Gen_1	733	741	PF02991	0.657
LIG_LIR_Gen_1	750	760	PF02991	0.262
LIG_LIR_Gen_1	9	20	PF02991	0.499
LIG_LIR_Nem_3	122	127	PF02991	0.385
LIG_LIR_Nem_3	283	288	PF02991	0.740
LIG_LIR_Nem_3	733	737	PF02991	0.660
LIG_LIR_Nem_3	750	755	PF02991	0.448
LIG_LIR_Nem_3	771	775	PF02991	0.385
LIG_LIR_Nem_3	9	15	PF02991	0.473
LIG_MYND_1	328	332	PF01753	0.600
LIG_MYND_1	333	337	PF01753	0.546
LIG_Pex14_1	353	357	PF04695	0.635
LIG_SH2_CRK	12	16	PF00017	0.481
LIG_SH2_STAT5	124	127	PF00017	0.385
LIG_SH2_STAT5	286	289	PF00017	0.607
LIG_SH2_STAT5	775	778	PF00017	0.385
LIG_SH3_1	382	388	PF00018	0.720
LIG_SH3_1	778	784	PF00018	0.309
LIG_SH3_2	133	138	PF14604	0.578
LIG_SH3_3	104	110	PF00018	0.385
LIG_SH3_3	115	121	PF00018	0.283
LIG_SH3_3	130	136	PF00018	0.543
LIG_SH3_3	243	249	PF00018	0.720
LIG_SH3_3	320	326	PF00018	0.659
LIG_SH3_3	331	337	PF00018	0.571
LIG_SH3_3	382	388	PF00018	0.737
LIG_SH3_3	406	412	PF00018	0.603
LIG_SH3_3	477	483	PF00018	0.656
LIG_SH3_3	656	662	PF00018	0.671
LIG_SH3_3	710	716	PF00018	0.574
LIG_SH3_3	778	784	PF00018	0.374
LIG_SH3_3	842	848	PF00018	0.604
LIG_SUMO_SIM_par_1	16	21	PF11976	0.523
LIG_SUMO_SIM_par_1	286	293	PF11976	0.653
LIG_TRAF2_1	371	374	PF00917	0.615
LIG_TYR_ITIM	10	15	PF00017	0.473
LIG_UBA3_1	287	291	PF00899	0.652
LIG_WW_3	135	139	PF00397	0.581
LIG_WW_3	452	456	PF00397	0.614
LIG_WW_3	629	633	PF00397	0.533
LIG_WW_3	682	686	PF00397	0.668
LIG_WW_3	689	693	PF00397	0.625
MOD_CDC14_SPxK_1	135	138	PF00782	0.581
MOD_CDC14_SPxK_1	468	471	PF00782	0.675
MOD_CDK_SPK_2	297	302	PF00069	0.573
MOD_CDK_SPxK_1	132	138	PF00069	0.574
MOD_CDK_SPxK_1	465	471	PF00069	0.679
MOD_CDK_SPxK_1	841	847	PF00069	0.603
MOD_CDK_SPxxK_3	141	148	PF00069	0.594
MOD_CDK_SPxxK_3	277	284	PF00069	0.586
MOD_CDK_SPxxK_3	295	302	PF00069	0.561
MOD_CDK_SPxxK_3	544	551	PF00069	0.584
MOD_CDK_SPxxK_3	643	650	PF00069	0.693
MOD_CK1_1	132	138	PF00069	0.677
MOD_CK1_1	140	146	PF00069	0.637
MOD_CK1_1	155	161	PF00069	0.524
MOD_CK1_1	164	170	PF00069	0.620
MOD_CK1_1	189	195	PF00069	0.689
MOD_CK1_1	196	202	PF00069	0.618
MOD_CK1_1	232	238	PF00069	0.653
MOD_CK1_1	242	248	PF00069	0.650
MOD_CK1_1	273	279	PF00069	0.596
MOD_CK1_1	297	303	PF00069	0.649
MOD_CK1_1	321	327	PF00069	0.649
MOD_CK1_1	367	373	PF00069	0.674
MOD_CK1_1	381	387	PF00069	0.542
MOD_CK1_1	396	402	PF00069	0.595
MOD_CK1_1	417	423	PF00069	0.617
MOD_CK1_1	478	484	PF00069	0.681
MOD_CK1_1	494	500	PF00069	0.559
MOD_CK1_1	531	537	PF00069	0.671
MOD_CK1_1	541	547	PF00069	0.610
MOD_CK1_1	557	563	PF00069	0.541
MOD_CK1_1	608	614	PF00069	0.687
MOD_CK1_1	69	75	PF00069	0.671
MOD_CK1_1	714	720	PF00069	0.627
MOD_CK2_1	368	374	PF00069	0.673
MOD_CK2_1	600	606	PF00069	0.645
MOD_CK2_1	618	624	PF00069	0.535
MOD_CK2_1	630	636	PF00069	0.582
MOD_CK2_1	719	725	PF00069	0.691
MOD_CK2_1	765	771	PF00069	0.342
MOD_CK2_1	794	800	PF00069	0.589
MOD_CK2_1	87	93	PF00069	0.342
MOD_GlcNHglycan	158	161	PF01048	0.654
MOD_GlcNHglycan	163	166	PF01048	0.643
MOD_GlcNHglycan	167	170	PF01048	0.616
MOD_GlcNHglycan	188	191	PF01048	0.692
MOD_GlcNHglycan	214	217	PF01048	0.696
MOD_GlcNHglycan	231	234	PF01048	0.649
MOD_GlcNHglycan	237	240	PF01048	0.584
MOD_GlcNHglycan	304	308	PF01048	0.593
MOD_GlcNHglycan	315	318	PF01048	0.554
MOD_GlcNHglycan	395	398	PF01048	0.595
MOD_GlcNHglycan	444	447	PF01048	0.674
MOD_GlcNHglycan	449	452	PF01048	0.622
MOD_GlcNHglycan	472	476	PF01048	0.652
MOD_GlcNHglycan	477	480	PF01048	0.683
MOD_GlcNHglycan	493	496	PF01048	0.554
MOD_GlcNHglycan	530	533	PF01048	0.646
MOD_GlcNHglycan	556	559	PF01048	0.649
MOD_GlcNHglycan	567	570	PF01048	0.616
MOD_GlcNHglycan	610	613	PF01048	0.647
MOD_GlcNHglycan	620	623	PF01048	0.574
MOD_GlcNHglycan	671	674	PF01048	0.613
MOD_GlcNHglycan	68	71	PF01048	0.686
MOD_GlcNHglycan	81	84	PF01048	0.699
MOD_GlcNHglycan	835	838	PF01048	0.667
MOD_GSK3_1	137	144	PF00069	0.677
MOD_GSK3_1	152	159	PF00069	0.527
MOD_GSK3_1	161	168	PF00069	0.603
MOD_GSK3_1	186	193	PF00069	0.690
MOD_GSK3_1	208	215	PF00069	0.588
MOD_GSK3_1	235	242	PF00069	0.705
MOD_GSK3_1	249	256	PF00069	0.617
MOD_GSK3_1	273	280	PF00069	0.659
MOD_GSK3_1	364	371	PF00069	0.670
MOD_GSK3_1	374	381	PF00069	0.580
MOD_GSK3_1	393	400	PF00069	0.631
MOD_GSK3_1	413	420	PF00069	0.548
MOD_GSK3_1	471	478	PF00069	0.678
MOD_GSK3_1	538	545	PF00069	0.668
MOD_GSK3_1	572	579	PF00069	0.620
MOD_GSK3_1	596	603	PF00069	0.665
MOD_GSK3_1	608	615	PF00069	0.600
MOD_GSK3_1	69	76	PF00069	0.751
MOD_N-GLC_1	664	669	PF02516	0.671
MOD_N-GLC_1	762	767	PF02516	0.385
MOD_N-GLC_1	826	831	PF02516	0.664
MOD_N-GLC_2	255	257	PF02516	0.615
MOD_N-GLC_2	277	279	PF02516	0.520
MOD_NEK2_1	597	602	PF00069	0.693
MOD_NEK2_1	669	674	PF00069	0.577
MOD_NEK2_1	741	746	PF00069	0.589
MOD_NEK2_1	764	769	PF00069	0.342
MOD_NEK2_1	95	100	PF00069	0.495
MOD_PIKK_1	168	174	PF00454	0.653
MOD_PIKK_1	224	230	PF00454	0.665
MOD_PIKK_1	417	423	PF00454	0.625
MOD_PIKK_1	695	701	PF00454	0.567
MOD_PIKK_1	741	747	PF00454	0.591
MOD_PKA_1	439	445	PF00069	0.653
MOD_PKA_2	137	143	PF00069	0.637
MOD_PKA_2	194	200	PF00069	0.640
MOD_PKA_2	229	235	PF00069	0.688
MOD_PKA_2	239	245	PF00069	0.554
MOD_PKA_2	311	317	PF00069	0.605
MOD_PKA_2	402	408	PF00069	0.673
MOD_PKA_2	439	445	PF00069	0.629
MOD_PKA_2	46	52	PF00069	0.514
MOD_PKA_2	470	476	PF00069	0.627
MOD_PKA_2	528	534	PF00069	0.600
MOD_PKA_2	66	72	PF00069	0.661
MOD_PKA_2	677	683	PF00069	0.621
MOD_PKA_2	779	785	PF00069	0.331
MOD_Plk_1	249	255	PF00069	0.740
MOD_Plk_1	664	670	PF00069	0.597
MOD_Plk_1	762	768	PF00069	0.385
MOD_Plk_2-3	751	757	PF00069	0.342
MOD_Plk_4	120	126	PF00069	0.513
MOD_Plk_4	719	725	PF00069	0.571
MOD_Plk_4	765	771	PF00069	0.342
MOD_ProDKin_1	129	135	PF00069	0.603
MOD_ProDKin_1	141	147	PF00069	0.567
MOD_ProDKin_1	242	248	PF00069	0.694
MOD_ProDKin_1	277	283	PF00069	0.628
MOD_ProDKin_1	295	301	PF00069	0.634
MOD_ProDKin_1	319	325	PF00069	0.642
MOD_ProDKin_1	348	354	PF00069	0.692
MOD_ProDKin_1	381	387	PF00069	0.656
MOD_ProDKin_1	465	471	PF00069	0.649
MOD_ProDKin_1	478	484	PF00069	0.567
MOD_ProDKin_1	519	525	PF00069	0.692
MOD_ProDKin_1	531	537	PF00069	0.587
MOD_ProDKin_1	544	550	PF00069	0.571
MOD_ProDKin_1	570	576	PF00069	0.637
MOD_ProDKin_1	605	611	PF00069	0.684
MOD_ProDKin_1	643	649	PF00069	0.543
MOD_ProDKin_1	658	664	PF00069	0.528
MOD_ProDKin_1	709	715	PF00069	0.590
MOD_ProDKin_1	826	832	PF00069	0.685
MOD_ProDKin_1	839	845	PF00069	0.548
TRG_DiLeu_BaEn_3	804	810	PF01217	0.572
TRG_ENDOCYTIC_2	12	15	PF00928	0.475
TRG_ENDOCYTIC_2	124	127	PF00928	0.385
TRG_ENDOCYTIC_2	285	288	PF00928	0.747
TRG_ENDOCYTIC_2	752	755	PF00928	0.385
TRG_ER_diArg_1	148	151	PF00400	0.694
TRG_ER_diArg_1	438	441	PF00400	0.652
TRG_ER_diArg_1	691	693	PF00400	0.686
TRG_ER_diArg_1	818	820	PF00400	0.554
TRG_ER_diArg_1	821	824	PF00400	0.561
TRG_NES_CRM1_1	86	101	PF08389	0.385
TRG_NLS_MonoExtC_3	776	781	PF00514	0.309
TRG_NLS_MonoExtN_4	774	781	PF00514	0.331

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJ04	Leishmania donovani	100%	100%
A4H8J2	Leishmania braziliensis	62%	99%
E9AQM9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4QEU9	Leishmania major	87%	100%