LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
XRN 5'-3' exonuclease N-terminus - putative
Species:
Leishmania infantum
UniProt:
A4HWT8_LEIIN
TriTrypDb:
LINF_160009000
Length:
1000

Annotations

Annotations by Jardim et al.

Nucleic acid binding, nucelase activity Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005730 nucleolus 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Abundance

Amastigote (protein)
Source Evidence on protein Close homologs
Pescher et al. (upgregulation) no yes: 0
Promastigote and amastigote
Source Evidence on protein Close homologs
Lahav et al.
- mRNA
- Protein

Expansion

Sequence features

A4HWT8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HWT8

Function

Biological processes
Term Name Level Count
GO:0000956 nuclear-transcribed mRNA catabolic process 7 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006401 RNA catabolic process 5 1
GO:0006402 mRNA catabolic process 6 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009056 catabolic process 2 1
GO:0009057 macromolecule catabolic process 4 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0009987 cellular process 1 1
GO:0010468 regulation of gene expression 5 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0010629 negative regulation of gene expression 6 1
GO:0016070 RNA metabolic process 5 1
GO:0016071 mRNA metabolic process 6 1
GO:0019222 regulation of metabolic process 3 1
GO:0019439 aromatic compound catabolic process 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0034655 nucleobase-containing compound catabolic process 4 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0044270 cellular nitrogen compound catabolic process 4 1
GO:0046483 heterocycle metabolic process 3 1
GO:0046700 heterocycle catabolic process 4 1
GO:0048519 negative regulation of biological process 3 1
GO:0050789 regulation of biological process 2 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071704 organic substance metabolic process 2 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1901361 organic cyclic compound catabolic process 4 1
GO:1901575 organic substance catabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 8
GO:0003824 catalytic activity 1 8
GO:0004518 nuclease activity 4 8
GO:0004527 exonuclease activity 5 8
GO:0005488 binding 1 8
GO:0016787 hydrolase activity 2 8
GO:0016788 hydrolase activity, acting on ester bonds 3 8
GO:0097159 organic cyclic compound binding 2 8
GO:1901363 heterocyclic compound binding 2 8
GO:0003723 RNA binding 4 1
GO:0004532 RNA exonuclease activity 5 1
GO:0004534 5'-3' RNA exonuclease activity 7 1
GO:0004540 RNA nuclease activity 4 1
GO:0008409 5'-3' exonuclease activity 6 1
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 1
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 1
GO:0140098 catalytic activity, acting on RNA 3 1
GO:0140640 catalytic activity, acting on a nucleic acid 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 47 51 PF00656 0.535
CLV_C14_Caspase3-7 728 732 PF00656 0.646
CLV_NRD_NRD_1 173 175 PF00675 0.211
CLV_NRD_NRD_1 220 222 PF00675 0.389
CLV_NRD_NRD_1 271 273 PF00675 0.542
CLV_NRD_NRD_1 280 282 PF00675 0.608
CLV_NRD_NRD_1 293 295 PF00675 0.555
CLV_NRD_NRD_1 34 36 PF00675 0.510
CLV_NRD_NRD_1 415 417 PF00675 0.367
CLV_NRD_NRD_1 6 8 PF00675 0.328
CLV_NRD_NRD_1 606 608 PF00675 0.485
CLV_NRD_NRD_1 71 73 PF00675 0.592
CLV_NRD_NRD_1 76 78 PF00675 0.619
CLV_NRD_NRD_1 764 766 PF00675 0.494
CLV_NRD_NRD_1 795 797 PF00675 0.492
CLV_NRD_NRD_1 799 801 PF00675 0.468
CLV_NRD_NRD_1 820 822 PF00675 0.554
CLV_NRD_NRD_1 911 913 PF00675 0.732
CLV_NRD_NRD_1 944 946 PF00675 0.609
CLV_NRD_NRD_1 947 949 PF00675 0.609
CLV_NRD_NRD_1 972 974 PF00675 0.565
CLV_NRD_NRD_1 996 998 PF00675 0.623
CLV_PCSK_FUR_1 170 174 PF00082 0.213
CLV_PCSK_FUR_1 291 295 PF00082 0.543
CLV_PCSK_FUR_1 945 949 PF00082 0.564
CLV_PCSK_KEX2_1 128 130 PF00082 0.162
CLV_PCSK_KEX2_1 172 174 PF00082 0.212
CLV_PCSK_KEX2_1 220 222 PF00082 0.395
CLV_PCSK_KEX2_1 271 273 PF00082 0.542
CLV_PCSK_KEX2_1 279 281 PF00082 0.630
CLV_PCSK_KEX2_1 293 295 PF00082 0.552
CLV_PCSK_KEX2_1 33 35 PF00082 0.508
CLV_PCSK_KEX2_1 415 417 PF00082 0.307
CLV_PCSK_KEX2_1 605 607 PF00082 0.450
CLV_PCSK_KEX2_1 71 73 PF00082 0.597
CLV_PCSK_KEX2_1 747 749 PF00082 0.448
CLV_PCSK_KEX2_1 75 77 PF00082 0.625
CLV_PCSK_KEX2_1 795 797 PF00082 0.492
CLV_PCSK_KEX2_1 799 801 PF00082 0.468
CLV_PCSK_KEX2_1 946 948 PF00082 0.587
CLV_PCSK_KEX2_1 971 973 PF00082 0.558
CLV_PCSK_KEX2_1 994 996 PF00082 0.640
CLV_PCSK_PC1ET2_1 128 130 PF00082 0.162
CLV_PCSK_PC1ET2_1 33 35 PF00082 0.520
CLV_PCSK_PC1ET2_1 747 749 PF00082 0.437
CLV_PCSK_PC1ET2_1 946 948 PF00082 0.556
CLV_PCSK_PC1ET2_1 994 996 PF00082 0.640
CLV_PCSK_PC7_1 216 222 PF00082 0.354
CLV_PCSK_PC7_1 71 77 PF00082 0.627
CLV_PCSK_PC7_1 795 801 PF00082 0.497
CLV_PCSK_SKI1_1 216 220 PF00082 0.303
CLV_PCSK_SKI1_1 266 270 PF00082 0.485
CLV_PCSK_SKI1_1 365 369 PF00082 0.414
CLV_PCSK_SKI1_1 570 574 PF00082 0.404
CLV_PCSK_SKI1_1 591 595 PF00082 0.354
CLV_PCSK_SKI1_1 705 709 PF00082 0.725
CLV_PCSK_SKI1_1 77 81 PF00082 0.619
CLV_PCSK_SKI1_1 813 817 PF00082 0.506
CLV_PCSK_SKI1_1 887 891 PF00082 0.607
CLV_PCSK_SKI1_1 905 909 PF00082 0.514
CLV_PCSK_SKI1_1 913 917 PF00082 0.570
CLV_PCSK_SKI1_1 947 951 PF00082 0.498
DEG_SCF_FBW7_1 521 527 PF00400 0.273
DEG_SPOP_SBC_1 255 259 PF00917 0.489
DEG_SPOP_SBC_1 78 82 PF00917 0.584
DOC_ANK_TNKS_1 34 41 PF00023 0.530
DOC_CDC14_PxL_1 643 651 PF14671 0.395
DOC_CKS1_1 521 526 PF01111 0.297
DOC_CKS1_1 789 794 PF01111 0.513
DOC_CKS1_1 986 991 PF01111 0.578
DOC_CYCLIN_yCln2_LP_2 644 650 PF00134 0.402
DOC_MAPK_DCC_7 636 646 PF00069 0.314
DOC_MAPK_gen_1 170 178 PF00069 0.443
DOC_MAPK_gen_1 220 227 PF00069 0.351
DOC_MAPK_gen_1 317 326 PF00069 0.392
DOC_MAPK_gen_1 570 578 PF00069 0.394
DOC_MAPK_MEF2A_6 150 157 PF00069 0.408
DOC_MAPK_MEF2A_6 388 396 PF00069 0.263
DOC_MAPK_RevD_3 161 175 PF00069 0.443
DOC_PP1_RVXF_1 240 247 PF00149 0.287
DOC_PP1_RVXF_1 386 392 PF00149 0.251
DOC_PP1_RVXF_1 651 658 PF00149 0.356
DOC_PP1_SILK_1 553 558 PF00149 0.391
DOC_PP2B_LxvP_1 19 22 PF13499 0.462
DOC_PP2B_LxvP_1 644 647 PF13499 0.399
DOC_PP2B_PxIxI_1 384 390 PF00149 0.287
DOC_PP4_FxxP_1 157 160 PF00568 0.443
DOC_PP4_FxxP_1 593 596 PF00568 0.346
DOC_PP4_FxxP_1 657 660 PF00568 0.307
DOC_PP4_FxxP_1 789 792 PF00568 0.514
DOC_USP7_MATH_1 149 153 PF00917 0.413
DOC_USP7_MATH_1 205 209 PF00917 0.331
DOC_USP7_MATH_1 248 252 PF00917 0.463
DOC_USP7_MATH_1 551 555 PF00917 0.333
DOC_USP7_MATH_1 721 725 PF00917 0.719
DOC_USP7_MATH_1 78 82 PF00917 0.584
DOC_USP7_MATH_1 854 858 PF00917 0.547
DOC_USP7_MATH_1 901 905 PF00917 0.496
DOC_USP7_MATH_1 95 99 PF00917 0.385
DOC_USP7_UBL2_3 886 890 PF12436 0.603
DOC_WW_Pin1_4 256 261 PF00397 0.608
DOC_WW_Pin1_4 347 352 PF00397 0.309
DOC_WW_Pin1_4 374 379 PF00397 0.472
DOC_WW_Pin1_4 428 433 PF00397 0.378
DOC_WW_Pin1_4 520 525 PF00397 0.305
DOC_WW_Pin1_4 592 597 PF00397 0.434
DOC_WW_Pin1_4 711 716 PF00397 0.576
DOC_WW_Pin1_4 788 793 PF00397 0.523
DOC_WW_Pin1_4 845 850 PF00397 0.503
DOC_WW_Pin1_4 97 102 PF00397 0.390
DOC_WW_Pin1_4 985 990 PF00397 0.579
LIG_14-3-3_CanoR_1 119 127 PF00244 0.381
LIG_14-3-3_CanoR_1 140 149 PF00244 0.443
LIG_14-3-3_CanoR_1 150 154 PF00244 0.443
LIG_14-3-3_CanoR_1 173 179 PF00244 0.443
LIG_14-3-3_CanoR_1 279 285 PF00244 0.466
LIG_14-3-3_CanoR_1 317 326 PF00244 0.336
LIG_14-3-3_CanoR_1 358 366 PF00244 0.340
LIG_14-3-3_CanoR_1 421 425 PF00244 0.344
LIG_14-3-3_CanoR_1 591 596 PF00244 0.408
LIG_14-3-3_CanoR_1 615 625 PF00244 0.366
LIG_14-3-3_CanoR_1 700 709 PF00244 0.681
LIG_14-3-3_CanoR_1 76 85 PF00244 0.557
LIG_14-3-3_CanoR_1 765 772 PF00244 0.477
LIG_14-3-3_CanoR_1 826 835 PF00244 0.494
LIG_14-3-3_CanoR_1 947 952 PF00244 0.553
LIG_Actin_WH2_2 352 370 PF00022 0.363
LIG_Actin_WH2_2 797 815 PF00022 0.535
LIG_BIR_III_2 846 850 PF00653 0.494
LIG_BRCT_BRCA1_1 153 157 PF00533 0.443
LIG_BRCT_BRCA1_1 903 907 PF00533 0.472
LIG_Clathr_ClatBox_1 197 201 PF01394 0.295
LIG_eIF4E_1 424 430 PF01652 0.373
LIG_FHA_1 14 20 PF00498 0.415
LIG_FHA_1 142 148 PF00498 0.400
LIG_FHA_1 166 172 PF00498 0.427
LIG_FHA_1 179 185 PF00498 0.512
LIG_FHA_1 187 193 PF00498 0.375
LIG_FHA_1 321 327 PF00498 0.352
LIG_FHA_1 563 569 PF00498 0.394
LIG_FHA_1 592 598 PF00498 0.347
LIG_FHA_1 64 70 PF00498 0.479
LIG_FHA_1 650 656 PF00498 0.403
LIG_FHA_1 777 783 PF00498 0.426
LIG_FHA_1 830 836 PF00498 0.410
LIG_FHA_1 98 104 PF00498 0.402
LIG_FHA_2 371 377 PF00498 0.482
LIG_FHA_2 43 49 PF00498 0.536
LIG_FHA_2 521 527 PF00498 0.298
LIG_FHA_2 559 565 PF00498 0.398
LIG_FHA_2 582 588 PF00498 0.336
LIG_FHA_2 712 718 PF00498 0.647
LIG_FHA_2 726 732 PF00498 0.547
LIG_FHA_2 889 895 PF00498 0.467
LIG_Integrin_RGD_1 374 376 PF01839 0.492
LIG_LIR_Apic_2 154 160 PF02991 0.443
LIG_LIR_Apic_2 656 660 PF02991 0.307
LIG_LIR_Gen_1 341 351 PF02991 0.274
LIG_LIR_Gen_1 390 397 PF02991 0.251
LIG_LIR_Gen_1 481 490 PF02991 0.441
LIG_LIR_Gen_1 526 536 PF02991 0.376
LIG_LIR_Gen_1 619 630 PF02991 0.416
LIG_LIR_Gen_1 652 661 PF02991 0.471
LIG_LIR_Nem_3 341 346 PF02991 0.273
LIG_LIR_Nem_3 361 367 PF02991 0.207
LIG_LIR_Nem_3 390 396 PF02991 0.251
LIG_LIR_Nem_3 481 485 PF02991 0.340
LIG_LIR_Nem_3 526 531 PF02991 0.361
LIG_LIR_Nem_3 619 625 PF02991 0.417
LIG_LIR_Nem_3 652 657 PF02991 0.426
LIG_Pex14_2 391 395 PF04695 0.249
LIG_Pex14_2 657 661 PF04695 0.343
LIG_PTB_Apo_2 642 649 PF02174 0.386
LIG_PTB_Phospho_1 642 648 PF10480 0.386
LIG_SH2_CRK 417 421 PF00017 0.284
LIG_SH2_CRK 482 486 PF00017 0.330
LIG_SH2_CRK 552 556 PF00017 0.292
LIG_SH2_GRB2like 57 60 PF00017 0.572
LIG_SH2_GRB2like 643 646 PF00017 0.374
LIG_SH2_GRB2like 750 753 PF00017 0.513
LIG_SH2_PTP2 528 531 PF00017 0.358
LIG_SH2_PTP2 622 625 PF00017 0.416
LIG_SH2_SRC 226 229 PF00017 0.283
LIG_SH2_SRC 484 487 PF00017 0.344
LIG_SH2_SRC 57 60 PF00017 0.524
LIG_SH2_SRC 643 646 PF00017 0.406
LIG_SH2_STAP1 651 655 PF00017 0.362
LIG_SH2_STAP1 931 935 PF00017 0.621
LIG_SH2_STAT3 750 753 PF00017 0.497
LIG_SH2_STAT5 226 229 PF00017 0.323
LIG_SH2_STAT5 315 318 PF00017 0.512
LIG_SH2_STAT5 403 406 PF00017 0.404
LIG_SH2_STAT5 451 454 PF00017 0.362
LIG_SH2_STAT5 484 487 PF00017 0.448
LIG_SH2_STAT5 528 531 PF00017 0.397
LIG_SH2_STAT5 589 592 PF00017 0.357
LIG_SH2_STAT5 622 625 PF00017 0.416
LIG_SH2_STAT5 643 646 PF00017 0.406
LIG_SH2_STAT5 648 651 PF00017 0.436
LIG_SH2_STAT5 654 657 PF00017 0.352
LIG_SH2_STAT5 658 661 PF00017 0.374
LIG_SH2_STAT5 750 753 PF00017 0.497
LIG_SH2_STAT5 823 826 PF00017 0.509
LIG_SH2_STAT5 99 102 PF00017 0.354
LIG_SH3_3 143 149 PF00018 0.410
LIG_SH3_3 375 381 PF00018 0.442
LIG_SH3_3 482 488 PF00018 0.381
LIG_SH3_3 518 524 PF00018 0.331
LIG_SH3_3 575 581 PF00018 0.401
LIG_SH3_3 598 604 PF00018 0.426
LIG_SH3_3 622 628 PF00018 0.405
LIG_SH3_3 644 650 PF00018 0.486
LIG_SH3_3 665 671 PF00018 0.476
LIG_SH3_4 126 133 PF00018 0.360
LIG_SUMO_SIM_anti_2 320 330 PF11976 0.292
LIG_SUMO_SIM_anti_2 526 535 PF11976 0.283
LIG_SUMO_SIM_par_1 188 193 PF11976 0.323
LIG_SUMO_SIM_par_1 198 203 PF11976 0.254
LIG_TRAF2_1 28 31 PF00917 0.617
LIG_TRAF2_1 756 759 PF00917 0.386
LIG_TYR_ITIM 362 367 PF00017 0.290
LIG_TYR_ITIM 641 646 PF00017 0.410
LIG_UBA3_1 3 8 PF00899 0.347
LIG_WRC_WIRS_1 976 981 PF05994 0.561
LIG_WW_3 602 606 PF00397 0.481
MOD_CDK_SPxxK_3 711 718 PF00069 0.526
MOD_CDK_SPxxK_3 788 795 PF00069 0.520
MOD_CK1_1 251 257 PF00069 0.585
MOD_CK1_1 297 303 PF00069 0.627
MOD_CK1_1 320 326 PF00069 0.325
MOD_CK1_1 347 353 PF00069 0.331
MOD_CK1_1 449 455 PF00069 0.414
MOD_CK1_1 470 476 PF00069 0.301
MOD_CK1_1 562 568 PF00069 0.420
MOD_CK1_1 83 89 PF00069 0.641
MOD_CK1_1 923 929 PF00069 0.547
MOD_CK2_1 21 27 PF00069 0.452
MOD_CK2_1 267 273 PF00069 0.600
MOD_CK2_1 297 303 PF00069 0.506
MOD_CK2_1 452 458 PF00069 0.405
MOD_CK2_1 520 526 PF00069 0.345
MOD_CK2_1 581 587 PF00069 0.340
MOD_CK2_1 606 612 PF00069 0.411
MOD_CK2_1 83 89 PF00069 0.615
MOD_CK2_1 845 851 PF00069 0.416
MOD_CK2_1 894 900 PF00069 0.538
MOD_CK2_1 975 981 PF00069 0.586
MOD_Cter_Amidation 277 280 PF01082 0.695
MOD_GlcNHglycan 250 253 PF01048 0.486
MOD_GlcNHglycan 296 299 PF01048 0.636
MOD_GlcNHglycan 370 373 PF01048 0.427
MOD_GlcNHglycan 465 468 PF01048 0.304
MOD_GlcNHglycan 52 55 PF01048 0.576
MOD_GlcNHglycan 577 581 PF01048 0.396
MOD_GlcNHglycan 59 62 PF01048 0.526
MOD_GlcNHglycan 683 686 PF01048 0.657
MOD_GlcNHglycan 709 712 PF01048 0.610
MOD_GlcNHglycan 723 726 PF01048 0.735
MOD_GlcNHglycan 742 745 PF01048 0.460
MOD_GlcNHglycan 766 769 PF01048 0.492
MOD_GlcNHglycan 779 782 PF01048 0.415
MOD_GlcNHglycan 808 811 PF01048 0.624
MOD_GlcNHglycan 878 881 PF01048 0.675
MOD_GlcNHglycan 89 92 PF01048 0.522
MOD_GlcNHglycan 896 899 PF01048 0.406
MOD_GlcNHglycan 981 985 PF01048 0.551
MOD_GlcNHglycan 989 992 PF01048 0.497
MOD_GSK3_1 174 181 PF00069 0.439
MOD_GSK3_1 186 193 PF00069 0.340
MOD_GSK3_1 251 258 PF00069 0.657
MOD_GSK3_1 370 377 PF00069 0.396
MOD_GSK3_1 379 386 PF00069 0.385
MOD_GSK3_1 420 427 PF00069 0.341
MOD_GSK3_1 445 452 PF00069 0.321
MOD_GSK3_1 463 470 PF00069 0.237
MOD_GSK3_1 516 523 PF00069 0.358
MOD_GSK3_1 534 541 PF00069 0.375
MOD_GSK3_1 551 558 PF00069 0.436
MOD_GSK3_1 560 567 PF00069 0.408
MOD_GSK3_1 707 714 PF00069 0.609
MOD_GSK3_1 721 728 PF00069 0.490
MOD_GSK3_1 79 86 PF00069 0.641
MOD_GSK3_1 876 883 PF00069 0.723
MOD_GSK3_1 9 16 PF00069 0.328
MOD_GSK3_1 901 908 PF00069 0.477
MOD_GSK3_1 93 100 PF00069 0.408
MOD_GSK3_1 985 992 PF00069 0.614
MOD_LATS_1 292 298 PF00433 0.499
MOD_LATS_1 698 704 PF00433 0.556
MOD_N-GLC_1 294 299 PF02516 0.674
MOD_N-GLC_1 344 349 PF02516 0.320
MOD_N-GLC_1 63 68 PF02516 0.498
MOD_N-GLC_1 721 726 PF02516 0.591
MOD_N-GLC_1 776 781 PF02516 0.341
MOD_NEK2_1 178 183 PF00069 0.441
MOD_NEK2_1 190 195 PF00069 0.285
MOD_NEK2_1 227 232 PF00069 0.282
MOD_NEK2_1 333 338 PF00069 0.271
MOD_NEK2_1 367 372 PF00069 0.470
MOD_NEK2_1 463 468 PF00069 0.254
MOD_NEK2_1 616 621 PF00069 0.377
MOD_NEK2_1 707 712 PF00069 0.566
MOD_NEK2_1 776 781 PF00069 0.439
MOD_NEK2_1 79 84 PF00069 0.761
MOD_NEK2_1 9 14 PF00069 0.333
MOD_NEK2_1 935 940 PF00069 0.577
MOD_NEK2_2 467 472 PF00069 0.289
MOD_OFUCOSY 112 117 PF10250 0.275
MOD_PIKK_1 165 171 PF00454 0.237
MOD_PIKK_1 205 211 PF00454 0.337
MOD_PIKK_1 379 385 PF00454 0.390
MOD_PIKK_1 516 522 PF00454 0.423
MOD_PK_1 280 286 PF00069 0.470
MOD_PKA_1 174 180 PF00069 0.454
MOD_PKA_1 279 285 PF00069 0.550
MOD_PKA_1 606 612 PF00069 0.411
MOD_PKA_1 947 953 PF00069 0.492
MOD_PKA_2 149 155 PF00069 0.297
MOD_PKA_2 279 285 PF00069 0.550
MOD_PKA_2 357 363 PF00069 0.344
MOD_PKA_2 420 426 PF00069 0.362
MOD_PKA_2 606 612 PF00069 0.411
MOD_PKA_2 764 770 PF00069 0.449
MOD_PKA_2 947 953 PF00069 0.544
MOD_PKB_1 172 180 PF00069 0.297
MOD_PKB_1 75 83 PF00069 0.610
MOD_PKB_1 945 953 PF00069 0.556
MOD_PKB_1 973 981 PF00069 0.562
MOD_PKB_1 985 993 PF00069 0.475
MOD_Plk_1 320 326 PF00069 0.311
MOD_Plk_1 344 350 PF00069 0.404
MOD_Plk_1 534 540 PF00069 0.344
MOD_Plk_1 905 911 PF00069 0.470
MOD_Plk_4 174 180 PF00069 0.479
MOD_Plk_4 193 199 PF00069 0.232
MOD_Plk_4 228 234 PF00069 0.345
MOD_Plk_4 320 326 PF00069 0.313
MOD_Plk_4 425 431 PF00069 0.366
MOD_Plk_4 470 476 PF00069 0.305
MOD_Plk_4 524 530 PF00069 0.274
MOD_Plk_4 551 557 PF00069 0.391
MOD_ProDKin_1 256 262 PF00069 0.609
MOD_ProDKin_1 347 353 PF00069 0.317
MOD_ProDKin_1 374 380 PF00069 0.460
MOD_ProDKin_1 428 434 PF00069 0.373
MOD_ProDKin_1 520 526 PF00069 0.305
MOD_ProDKin_1 592 598 PF00069 0.432
MOD_ProDKin_1 711 717 PF00069 0.576
MOD_ProDKin_1 788 794 PF00069 0.520
MOD_ProDKin_1 845 851 PF00069 0.504
MOD_ProDKin_1 97 103 PF00069 0.374
MOD_ProDKin_1 985 991 PF00069 0.579
MOD_SUMO_rev_2 123 127 PF00179 0.247
MOD_SUMO_rev_2 235 241 PF00179 0.276
MOD_SUMO_rev_2 740 749 PF00179 0.461
MOD_SUMO_rev_2 758 768 PF00179 0.642
MOD_SUMO_rev_2 819 824 PF00179 0.513
TRG_DiLeu_BaEn_1 851 856 PF01217 0.387
TRG_DiLeu_BaEn_2 837 843 PF01217 0.497
TRG_DiLeu_BaLyEn_6 14 19 PF01217 0.403
TRG_ENDOCYTIC_2 364 367 PF00928 0.303
TRG_ENDOCYTIC_2 417 420 PF00928 0.287
TRG_ENDOCYTIC_2 482 485 PF00928 0.331
TRG_ENDOCYTIC_2 528 531 PF00928 0.358
TRG_ENDOCYTIC_2 552 555 PF00928 0.298
TRG_ENDOCYTIC_2 622 625 PF00928 0.416
TRG_ENDOCYTIC_2 643 646 PF00928 0.377
TRG_ENDOCYTIC_2 654 657 PF00928 0.348
TRG_ENDOCYTIC_2 658 661 PF00928 0.381
TRG_ENDOCYTIC_2 99 102 PF00928 0.483
TRG_ER_diArg_1 138 141 PF00400 0.237
TRG_ER_diArg_1 170 173 PF00400 0.254
TRG_ER_diArg_1 219 221 PF00400 0.360
TRG_ER_diArg_1 279 281 PF00400 0.609
TRG_ER_diArg_1 291 294 PF00400 0.520
TRG_ER_diArg_1 316 319 PF00400 0.459
TRG_ER_diArg_1 34 37 PF00400 0.524
TRG_ER_diArg_1 414 416 PF00400 0.371
TRG_ER_diArg_1 604 607 PF00400 0.508
TRG_ER_diArg_1 75 77 PF00400 0.640
TRG_ER_diArg_1 760 763 PF00400 0.532
TRG_ER_diArg_1 795 797 PF00400 0.488
TRG_ER_diArg_1 799 801 PF00400 0.464
TRG_ER_diArg_1 945 948 PF00400 0.564
TRG_ER_diArg_1 971 973 PF00400 0.618
TRG_ER_diArg_1 995 997 PF00400 0.640
TRG_NES_CRM1_1 130 145 PF08389 0.297
TRG_NES_CRM1_1 520 535 PF08389 0.368
TRG_NLS_MonoCore_2 944 949 PF00514 0.515
TRG_NLS_MonoCore_2 992 997 PF00514 0.635
TRG_NLS_MonoExtC_3 32 37 PF00514 0.526
TRG_NLS_MonoExtC_3 992 997 PF00514 0.635
TRG_NLS_MonoExtN_4 943 950 PF00514 0.577
TRG_NLS_MonoExtN_4 993 998 PF00514 0.633
TRG_Pf-PMV_PEXEL_1 129 133 PF00026 0.211
TRG_Pf-PMV_PEXEL_1 140 145 PF00026 0.280
TRG_Pf-PMV_PEXEL_1 34 39 PF00026 0.501
TRG_Pf-PMV_PEXEL_1 833 838 PF00026 0.448

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IM29 Leptomonas seymouri 66% 100%
A0A3S7WTU7 Leishmania donovani 100% 100%
A4H8G4 Leishmania braziliensis 77% 99%
C9ZPR7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 100%
E9AQJ6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 98%
Q4QEY1 Leishmania major 89% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS