Phosphatase, tyrosine phosphatase-likie
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 2 |
| Forrest at al. (procyclic) | yes | yes: 4 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 27 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 10 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 23 |
| NetGPI | no | yes: 0, no: 23 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 2 |
| GO:0005737 | cytoplasm | 2 | 2 |
| GO:0005829 | cytosol | 2 | 1 |
| GO:0018995 | host cellular component | 2 | 1 |
| GO:0020023 | kinetoplast | 2 | 1 |
| GO:0030430 | host cell cytoplasm | 5 | 1 |
| GO:0031982 | vesicle | 4 | 1 |
| GO:0033643 | host cell part | 3 | 1 |
| GO:0033646 | host intracellular part | 4 | 1 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043227 | membrane-bounded organelle | 3 | 2 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043230 | extracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 2 |
| GO:0065010 | extracellular membrane-bounded organelle | 4 | 1 |
| GO:0070062 | extracellular exosome | 6 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:1903561 | extracellular vesicle | 5 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006470 | protein dephosphorylation | 5 | 24 |
| GO:0006793 | phosphorus metabolic process | 3 | 24 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 24 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 24 |
| GO:0008152 | metabolic process | 1 | 24 |
| GO:0009987 | cellular process | 1 | 24 |
| GO:0016311 | dephosphorylation | 5 | 24 |
| GO:0019538 | protein metabolic process | 3 | 24 |
| GO:0036211 | protein modification process | 4 | 24 |
| GO:0043170 | macromolecule metabolic process | 3 | 24 |
| GO:0043412 | macromolecule modification | 4 | 24 |
| GO:0044237 | cellular metabolic process | 2 | 24 |
| GO:0044238 | primary metabolic process | 2 | 24 |
| GO:0071704 | organic substance metabolic process | 2 | 24 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 24 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 24 |
| GO:0004721 | phosphoprotein phosphatase activity | 3 | 24 |
| GO:0004725 | protein tyrosine phosphatase activity | 4 | 17 |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | 4 | 24 |
| GO:0016787 | hydrolase activity | 2 | 24 |
| GO:0016788 | hydrolase activity, acting on ester bonds | 3 | 24 |
| GO:0016791 | phosphatase activity | 5 | 24 |
| GO:0042578 | phosphoric ester hydrolase activity | 4 | 24 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 24 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 140 | 142 | PF00675 | 0.335 |
| CLV_PCSK_FUR_1 | 138 | 142 | PF00082 | 0.334 |
| CLV_PCSK_KEX2_1 | 11 | 13 | PF00082 | 0.420 |
| CLV_PCSK_KEX2_1 | 140 | 142 | PF00082 | 0.334 |
| CLV_PCSK_PC1ET2_1 | 11 | 13 | PF00082 | 0.446 |
| DEG_Nend_UBRbox_2 | 1 | 3 | PF02207 | 0.515 |
| DEG_SCF_FBW7_1 | 95 | 102 | PF00400 | 0.449 |
| DOC_CDC14_PxL_1 | 111 | 119 | PF14671 | 0.334 |
| DOC_CYCLIN_RxL_1 | 18 | 29 | PF00134 | 0.400 |
| DOC_MAPK_MEF2A_6 | 113 | 122 | PF00069 | 0.338 |
| DOC_PP2B_LxvP_1 | 25 | 28 | PF13499 | 0.400 |
| DOC_SPAK_OSR1_1 | 21 | 25 | PF12202 | 0.363 |
| DOC_USP7_MATH_1 | 28 | 32 | PF00917 | 0.424 |
| DOC_WW_Pin1_4 | 26 | 31 | PF00397 | 0.414 |
| DOC_WW_Pin1_4 | 95 | 100 | PF00397 | 0.364 |
| LIG_BIR_III_4 | 132 | 136 | PF00653 | 0.328 |
| LIG_Clathr_ClatBox_1 | 90 | 94 | PF01394 | 0.291 |
| LIG_FHA_1 | 100 | 106 | PF00498 | 0.366 |
| LIG_FHA_1 | 13 | 19 | PF00498 | 0.452 |
| LIG_FHA_1 | 78 | 84 | PF00498 | 0.399 |
| LIG_FHA_2 | 4 | 10 | PF00498 | 0.421 |
| LIG_FHA_2 | 70 | 76 | PF00498 | 0.346 |
| LIG_FHA_2 | 96 | 102 | PF00498 | 0.435 |
| LIG_LIR_Gen_1 | 35 | 40 | PF02991 | 0.459 |
| LIG_LIR_Gen_1 | 85 | 95 | PF02991 | 0.376 |
| LIG_LIR_Nem_3 | 17 | 23 | PF02991 | 0.389 |
| LIG_LIR_Nem_3 | 35 | 39 | PF02991 | 0.308 |
| LIG_LIR_Nem_3 | 85 | 90 | PF02991 | 0.357 |
| LIG_Pex14_1 | 152 | 156 | PF04695 | 0.413 |
| LIG_SH2_PTP2 | 36 | 39 | PF00017 | 0.430 |
| LIG_SH2_STAT5 | 136 | 139 | PF00017 | 0.341 |
| LIG_SH2_STAT5 | 36 | 39 | PF00017 | 0.419 |
| LIG_SUMO_SIM_anti_2 | 85 | 92 | PF11976 | 0.453 |
| LIG_SUMO_SIM_par_1 | 89 | 94 | PF11976 | 0.271 |
| LIG_UBA3_1 | 90 | 97 | PF00899 | 0.407 |
| MOD_CAAXbox | 173 | 176 | PF01239 | 0.548 |
| MOD_CK1_1 | 164 | 170 | PF00069 | 0.657 |
| MOD_CK1_1 | 29 | 35 | PF00069 | 0.398 |
| MOD_CK2_1 | 95 | 101 | PF00069 | 0.347 |
| MOD_GSK3_1 | 28 | 35 | PF00069 | 0.493 |
| MOD_GSK3_1 | 95 | 102 | PF00069 | 0.311 |
| MOD_N-GLC_1 | 12 | 17 | PF02516 | 0.434 |
| MOD_N-GLC_1 | 3 | 8 | PF02516 | 0.416 |
| MOD_Plk_1 | 164 | 170 | PF00069 | 0.559 |
| MOD_Plk_2-3 | 89 | 95 | PF00069 | 0.271 |
| MOD_Plk_4 | 3 | 9 | PF00069 | 0.423 |
| MOD_Plk_4 | 32 | 38 | PF00069 | 0.519 |
| MOD_Plk_4 | 83 | 89 | PF00069 | 0.357 |
| MOD_ProDKin_1 | 26 | 32 | PF00069 | 0.413 |
| MOD_ProDKin_1 | 95 | 101 | PF00069 | 0.364 |
| TRG_ENDOCYTIC_2 | 125 | 128 | PF00928 | 0.349 |
| TRG_ENDOCYTIC_2 | 36 | 39 | PF00928 | 0.414 |
| TRG_ER_diArg_1 | 156 | 159 | PF00400 | 0.504 |
| TRG_Pf-PMV_PEXEL_1 | 21 | 26 | PF00026 | 0.397 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7Y8 | Leptomonas seymouri | 61% | 100% |
| A0A0N1IM31 | Leptomonas seymouri | 88% | 100% |
| A0A0S4IS65 | Bodo saltans | 68% | 97% |
| A0A1X0NFW2 | Trypanosomatidae | 57% | 100% |
| A0A1X0NHQ7 | Trypanosomatidae | 77% | 100% |
| A0A1X0NZ52 | Trypanosomatidae | 61% | 100% |
| A0A3Q8I9A9 | Leishmania donovani | 61% | 100% |
| A0A3S5IQZ9 | Trypanosoma rangeli | 73% | 100% |
| A0A3S7WTS0 | Leishmania donovani | 99% | 100% |
| A0A422N2F6 | Trypanosoma rangeli | 71% | 100% |
| A0A422ND97 | Trypanosoma rangeli | 61% | 100% |
| A2VDT1 | Bos taurus | 44% | 100% |
| A4H8E9 | Leishmania braziliensis | 61% | 100% |
| A4H8F1 | Leishmania braziliensis | 94% | 100% |
| A4HWS2 | Leishmania infantum | 61% | 100% |
| C9ZW52 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 58% | 100% |
| E9AQI0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 62% | 100% |
| E9AQI2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 98% | 100% |
| O61722 | Drosophila melanogaster | 44% | 100% |
| O70274 | Mus musculus | 50% | 100% |
| O75365 | Homo sapiens | 44% | 100% |
| Q12974 | Homo sapiens | 50% | 100% |
| Q4CUJ8 | Trypanosoma cruzi (strain CL Brener) | 73% | 100% |
| Q4QEZ5 | Leishmania major | 97% | 100% |
| Q4QEZ7 | Leishmania major | 62% | 100% |
| Q54DU9 | Dictyostelium discoideum | 54% | 100% |
| Q5R7J8 | Pongo abelii | 46% | 100% |
| Q63739 | Mus musculus | 46% | 100% |
| Q6NT99 | Mus musculus | 29% | 100% |
| Q6P9X4 | Rattus norvegicus | 50% | 100% |
| Q78EG7 | Rattus norvegicus | 46% | 100% |
| Q86IL4 | Dictyostelium discoideum | 38% | 100% |
| Q93096 | Homo sapiens | 46% | 100% |
| Q9D658 | Mus musculus | 45% | 100% |
| Q9TSM6 | Macaca fascicularis | 46% | 100% |
| V5B959 | Trypanosoma cruzi | 60% | 98% |
| V5BA64 | Trypanosoma cruzi | 73% | 100% |
| V5BDR5 | Trypanosoma cruzi | 73% | 100% |