Phosphatase, tyrosine phosphatase-like
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | yes | yes: 2 |
| Forrest at al. (procyclic) | yes | yes: 4 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 27 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 10 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 23 |
| NetGPI | no | yes: 0, no: 23 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 2 |
| GO:0005737 | cytoplasm | 2 | 2 |
| GO:0005829 | cytosol | 2 | 1 |
| GO:0018995 | host cellular component | 2 | 1 |
| GO:0020023 | kinetoplast | 2 | 1 |
| GO:0030430 | host cell cytoplasm | 5 | 1 |
| GO:0031982 | vesicle | 4 | 1 |
| GO:0033643 | host cell part | 3 | 1 |
| GO:0033646 | host intracellular part | 4 | 1 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043227 | membrane-bounded organelle | 3 | 2 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043230 | extracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 2 |
| GO:0065010 | extracellular membrane-bounded organelle | 4 | 1 |
| GO:0070062 | extracellular exosome | 6 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:1903561 | extracellular vesicle | 5 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006470 | protein dephosphorylation | 5 | 24 |
| GO:0006793 | phosphorus metabolic process | 3 | 24 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 24 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 24 |
| GO:0008152 | metabolic process | 1 | 24 |
| GO:0009987 | cellular process | 1 | 24 |
| GO:0016311 | dephosphorylation | 5 | 24 |
| GO:0019538 | protein metabolic process | 3 | 24 |
| GO:0036211 | protein modification process | 4 | 24 |
| GO:0043170 | macromolecule metabolic process | 3 | 24 |
| GO:0043412 | macromolecule modification | 4 | 24 |
| GO:0044237 | cellular metabolic process | 2 | 24 |
| GO:0044238 | primary metabolic process | 2 | 24 |
| GO:0071704 | organic substance metabolic process | 2 | 24 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 24 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 24 |
| GO:0004721 | phosphoprotein phosphatase activity | 3 | 24 |
| GO:0004725 | protein tyrosine phosphatase activity | 4 | 17 |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | 4 | 24 |
| GO:0016787 | hydrolase activity | 2 | 24 |
| GO:0016788 | hydrolase activity, acting on ester bonds | 3 | 24 |
| GO:0016791 | phosphatase activity | 5 | 24 |
| GO:0042578 | phosphoric ester hydrolase activity | 4 | 24 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 24 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 136 | 140 | PF00656 | 0.348 |
| CLV_NRD_NRD_1 | 148 | 150 | PF00675 | 0.252 |
| CLV_NRD_NRD_1 | 165 | 167 | PF00675 | 0.359 |
| CLV_PCSK_FUR_1 | 145 | 149 | PF00082 | 0.253 |
| CLV_PCSK_KEX2_1 | 147 | 149 | PF00082 | 0.253 |
| CLV_PCSK_KEX2_1 | 164 | 166 | PF00082 | 0.365 |
| CLV_PCSK_PC1ET2_1 | 147 | 149 | PF00082 | 0.258 |
| CLV_PCSK_PC1ET2_1 | 164 | 166 | PF00082 | 0.314 |
| CLV_PCSK_SKI1_1 | 18 | 22 | PF00082 | 0.333 |
| CLV_PCSK_SKI1_1 | 82 | 86 | PF00082 | 0.295 |
| DEG_Nend_UBRbox_2 | 1 | 3 | PF02207 | 0.426 |
| DOC_CDC14_PxL_1 | 118 | 126 | PF14671 | 0.253 |
| DOC_MAPK_gen_1 | 44 | 52 | PF00069 | 0.278 |
| DOC_MAPK_MEF2A_6 | 120 | 129 | PF00069 | 0.256 |
| DOC_PP1_RVXF_1 | 16 | 22 | PF00149 | 0.395 |
| DOC_PP2B_LxvP_1 | 26 | 29 | PF13499 | 0.350 |
| DOC_PP2B_PxIxI_1 | 107 | 113 | PF00149 | 0.397 |
| DOC_USP7_MATH_1 | 29 | 33 | PF00917 | 0.348 |
| DOC_WW_Pin1_4 | 27 | 32 | PF00397 | 0.337 |
| LIG_BRCT_BRCA1_1 | 70 | 74 | PF00533 | 0.276 |
| LIG_FHA_1 | 107 | 113 | PF00498 | 0.285 |
| LIG_FHA_1 | 79 | 85 | PF00498 | 0.320 |
| LIG_FHA_2 | 4 | 10 | PF00498 | 0.345 |
| LIG_LIR_Gen_1 | 86 | 96 | PF02991 | 0.295 |
| LIG_LIR_Nem_3 | 131 | 135 | PF02991 | 0.276 |
| LIG_LIR_Nem_3 | 86 | 91 | PF02991 | 0.276 |
| LIG_Pex14_1 | 159 | 163 | PF04695 | 0.344 |
| LIG_SH2_CRK | 132 | 136 | PF00017 | 0.320 |
| LIG_SH2_STAP1 | 57 | 61 | PF00017 | 0.365 |
| LIG_SH2_STAT5 | 37 | 40 | PF00017 | 0.349 |
| LIG_SH3_2 | 13 | 18 | PF14604 | 0.332 |
| LIG_SH3_3 | 10 | 16 | PF00018 | 0.315 |
| LIG_SH3_3 | 100 | 106 | PF00018 | 0.230 |
| LIG_SH3_3 | 49 | 55 | PF00018 | 0.321 |
| LIG_SUMO_SIM_anti_2 | 139 | 146 | PF11976 | 0.260 |
| LIG_TYR_ITIM | 130 | 135 | PF00017 | 0.295 |
| MOD_CAAXbox | 172 | 175 | PF01239 | 0.516 |
| MOD_GlcNHglycan | 135 | 138 | PF01048 | 0.348 |
| MOD_GlcNHglycan | 168 | 171 | PF01048 | 0.442 |
| MOD_GSK3_1 | 29 | 36 | PF00069 | 0.427 |
| MOD_GSK3_1 | 53 | 60 | PF00069 | 0.357 |
| MOD_N-GLC_1 | 133 | 138 | PF02516 | 0.441 |
| MOD_N-GLC_1 | 152 | 157 | PF02516 | 0.141 |
| MOD_N-GLC_1 | 3 | 8 | PF02516 | 0.334 |
| MOD_NEK2_1 | 61 | 66 | PF00069 | 0.296 |
| MOD_PIKK_1 | 152 | 158 | PF00454 | 0.265 |
| MOD_PKA_2 | 14 | 20 | PF00069 | 0.239 |
| MOD_Plk_1 | 133 | 139 | PF00069 | 0.441 |
| MOD_Plk_1 | 152 | 158 | PF00069 | 0.141 |
| MOD_Plk_1 | 3 | 9 | PF00069 | 0.323 |
| MOD_Plk_1 | 57 | 63 | PF00069 | 0.358 |
| MOD_Plk_4 | 3 | 9 | PF00069 | 0.344 |
| MOD_Plk_4 | 33 | 39 | PF00069 | 0.471 |
| MOD_Plk_4 | 57 | 63 | PF00069 | 0.391 |
| MOD_Plk_4 | 84 | 90 | PF00069 | 0.276 |
| MOD_ProDKin_1 | 27 | 33 | PF00069 | 0.336 |
| TRG_ENDOCYTIC_2 | 132 | 135 | PF00928 | 0.267 |
| TRG_NLS_Bipartite_1 | 147 | 168 | PF00514 | 0.455 |
| TRG_NLS_MonoExtN_4 | 162 | 168 | PF00514 | 0.471 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7Y8 | Leptomonas seymouri | 76% | 99% |
| A0A0N1IM31 | Leptomonas seymouri | 59% | 99% |
| A0A0S4IS65 | Bodo saltans | 60% | 97% |
| A0A1X0NFW2 | Trypanosomatidae | 68% | 99% |
| A0A1X0NHQ7 | Trypanosomatidae | 59% | 99% |
| A0A1X0NZ52 | Trypanosomatidae | 68% | 99% |
| A0A3Q8I9A9 | Leishmania donovani | 99% | 100% |
| A0A3S5IQZ9 | Trypanosoma rangeli | 55% | 99% |
| A0A3S7WTS0 | Leishmania donovani | 61% | 99% |
| A0A422N2F6 | Trypanosoma rangeli | 51% | 100% |
| A0A422ND97 | Trypanosoma rangeli | 66% | 99% |
| A2VDT1 | Bos taurus | 46% | 100% |
| A4H8E9 | Leishmania braziliensis | 90% | 100% |
| A4H8F1 | Leishmania braziliensis | 60% | 100% |
| A4HWS4 | Leishmania infantum | 61% | 99% |
| C9ZW52 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 70% | 99% |
| E9AQI0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 96% | 100% |
| E9AQI2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 61% | 100% |
| O61722 | Drosophila melanogaster | 42% | 99% |
| O70274 | Mus musculus | 46% | 100% |
| O75365 | Homo sapiens | 47% | 100% |
| Q12974 | Homo sapiens | 46% | 100% |
| Q4CUJ8 | Trypanosoma cruzi (strain CL Brener) | 52% | 99% |
| Q4QEZ5 | Leishmania major | 60% | 100% |
| Q4QEZ7 | Leishmania major | 97% | 100% |
| Q54DU9 | Dictyostelium discoideum | 48% | 100% |
| Q5R7J8 | Pongo abelii | 49% | 100% |
| Q63739 | Mus musculus | 50% | 100% |
| Q6NT99 | Mus musculus | 34% | 100% |
| Q6P9X4 | Rattus norvegicus | 46% | 100% |
| Q78EG7 | Rattus norvegicus | 50% | 100% |
| Q86IL4 | Dictyostelium discoideum | 33% | 100% |
| Q93096 | Homo sapiens | 50% | 100% |
| Q9BVJ7 | Homo sapiens | 32% | 100% |
| Q9D658 | Mus musculus | 48% | 100% |
| Q9TSM6 | Macaca fascicularis | 50% | 100% |
| V5B959 | Trypanosoma cruzi | 68% | 97% |
| V5BA64 | Trypanosoma cruzi | 52% | 99% |
| V5BDR5 | Trypanosoma cruzi | 56% | 99% |