Translation, eukaryotic translation initiation factor 1A
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | yes | yes: 12 |
| Pissara et al. | yes | yes: 20 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | yes | yes: 21 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pescher et al. (upgregulation) | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
|
Lahav et al. - mRNA
- Protein
|
Related structures:
AlphaFold database: A4HWR3
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006413 | translational initiation | 3 | 1 |
| GO:0008152 | metabolic process | 1 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 11 |
| GO:0003723 | RNA binding | 4 | 11 |
| GO:0003743 | translation initiation factor activity | 4 | 11 |
| GO:0005488 | binding | 1 | 11 |
| GO:0008135 | translation factor activity, RNA binding | 3 | 11 |
| GO:0045182 | translation regulator activity | 1 | 11 |
| GO:0090079 | translation regulator activity, nucleic acid binding | 2 | 11 |
| GO:0097159 | organic cyclic compound binding | 2 | 11 |
| GO:1901363 | heterocyclic compound binding | 2 | 11 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 122 | 126 | PF00656 | 0.487 |
| CLV_NRD_NRD_1 | 70 | 72 | PF00675 | 0.190 |
| CLV_PCSK_KEX2_1 | 25 | 27 | PF00082 | 0.468 |
| CLV_PCSK_KEX2_1 | 85 | 87 | PF00082 | 0.195 |
| CLV_PCSK_PC1ET2_1 | 25 | 27 | PF00082 | 0.454 |
| CLV_PCSK_PC1ET2_1 | 85 | 87 | PF00082 | 0.203 |
| CLV_PCSK_SKI1_1 | 10 | 14 | PF00082 | 0.487 |
| CLV_PCSK_SKI1_1 | 26 | 30 | PF00082 | 0.422 |
| CLV_PCSK_SKI1_1 | 43 | 47 | PF00082 | 0.177 |
| DEG_APCC_KENBOX_2 | 109 | 113 | PF00400 | 0.491 |
| DOC_MAPK_gen_1 | 43 | 51 | PF00069 | 0.389 |
| DOC_MAPK_MEF2A_6 | 44 | 53 | PF00069 | 0.403 |
| DOC_USP7_MATH_1 | 14 | 18 | PF00917 | 0.608 |
| DOC_USP7_MATH_1 | 56 | 60 | PF00917 | 0.417 |
| DOC_USP7_UBL2_3 | 3 | 7 | PF12436 | 0.488 |
| DOC_WW_Pin1_4 | 98 | 103 | PF00397 | 0.513 |
| LIG_FHA_1 | 128 | 134 | PF00498 | 0.656 |
| LIG_FHA_2 | 99 | 105 | PF00498 | 0.351 |
| LIG_LIR_Apic_2 | 27 | 33 | PF02991 | 0.469 |
| LIG_LIR_Gen_1 | 130 | 139 | PF02991 | 0.467 |
| LIG_LIR_Gen_1 | 37 | 46 | PF02991 | 0.390 |
| LIG_LIR_Nem_3 | 130 | 135 | PF02991 | 0.467 |
| LIG_LIR_Nem_3 | 37 | 42 | PF02991 | 0.390 |
| LIG_PDZ_Class_3 | 163 | 168 | PF00595 | 0.422 |
| LIG_SH2_CRK | 39 | 43 | PF00017 | 0.389 |
| LIG_SH2_GRB2like | 30 | 33 | PF00017 | 0.452 |
| LIG_SH2_NCK_1 | 30 | 34 | PF00017 | 0.473 |
| LIG_SH2_PTP2 | 132 | 135 | PF00017 | 0.478 |
| LIG_SH2_SRC | 30 | 33 | PF00017 | 0.467 |
| LIG_SH2_STAT5 | 132 | 135 | PF00017 | 0.478 |
| LIG_SUMO_SIM_anti_2 | 79 | 84 | PF11976 | 0.389 |
| LIG_SUMO_SIM_anti_2 | 92 | 98 | PF11976 | 0.389 |
| LIG_TRAF2_1 | 120 | 123 | PF00917 | 0.555 |
| LIG_TYR_ITSM | 128 | 135 | PF00017 | 0.537 |
| MOD_CK2_1 | 117 | 123 | PF00069 | 0.317 |
| MOD_CK2_1 | 98 | 104 | PF00069 | 0.494 |
| MOD_GlcNHglycan | 119 | 122 | PF01048 | 0.546 |
| MOD_NEK2_2 | 8 | 13 | PF00069 | 0.463 |
| MOD_Plk_1 | 26 | 32 | PF00069 | 0.525 |
| MOD_Plk_4 | 57 | 63 | PF00069 | 0.459 |
| MOD_ProDKin_1 | 98 | 104 | PF00069 | 0.511 |
| MOD_SUMO_for_1 | 84 | 87 | PF00179 | 0.441 |
| TRG_DiLeu_BaEn_1 | 104 | 109 | PF01217 | 0.317 |
| TRG_DiLeu_BaLyEn_6 | 103 | 108 | PF01217 | 0.392 |
| TRG_ENDOCYTIC_2 | 132 | 135 | PF00928 | 0.478 |
| TRG_ENDOCYTIC_2 | 39 | 42 | PF00928 | 0.389 |
| TRG_Pf-PMV_PEXEL_1 | 106 | 111 | PF00026 | 0.359 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7Z1 | Leptomonas seymouri | 88% | 100% |
| A0A0S4JME0 | Bodo saltans | 57% | 94% |
| A0A1X0NFW8 | Trypanosomatidae | 72% | 99% |
| A0A3S5H6W6 | Leishmania donovani | 100% | 100% |
| A0A422NDF4 | Trypanosoma rangeli | 71% | 100% |
| A4H8E1 | Leishmania braziliensis | 99% | 100% |
| C9ZW61 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 74% | 98% |
| E9AQH1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 99% | 100% |
| O14602 | Homo sapiens | 37% | 100% |
| P38912 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 40% | 100% |
| P47813 | Homo sapiens | 37% | 100% |
| P47814 | Oryctolagus cuniculus | 42% | 100% |
| P47815 | Triticum aestivum | 40% | 100% |
| P55877 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 46% | 100% |
| P56331 | Onobrychis viciifolia | 38% | 100% |
| Q4QF06 | Leishmania major | 100% | 100% |
| Q54YJ6 | Dictyostelium discoideum | 40% | 100% |
| Q5RA42 | Pongo abelii | 37% | 100% |
| Q60872 | Mus musculus | 39% | 100% |
| Q6GVM3 | Pan troglodytes | 37% | 100% |
| Q6VV72 | Rattus norvegicus | 39% | 100% |
| Q8BMJ3 | Mus musculus | 37% | 100% |