LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania infantum
UniProt:
A4HWF8_LEIIN
TriTrypDb:
LINF_150013300
Length:
1767

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HWF8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HWF8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1049 1053 PF00656 0.612
CLV_C14_Caspase3-7 1336 1340 PF00656 0.465
CLV_C14_Caspase3-7 1547 1551 PF00656 0.615
CLV_C14_Caspase3-7 224 228 PF00656 0.617
CLV_C14_Caspase3-7 289 293 PF00656 0.640
CLV_C14_Caspase3-7 805 809 PF00656 0.655
CLV_NRD_NRD_1 1029 1031 PF00675 0.640
CLV_NRD_NRD_1 1148 1150 PF00675 0.644
CLV_NRD_NRD_1 122 124 PF00675 0.626
CLV_NRD_NRD_1 1252 1254 PF00675 0.553
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8I942 Leishmania donovani 99% 100%
A4H832 Leishmania braziliensis 57% 100%
E9AQ57 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS