Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - unknown function

Species:

Leishmania infantum

UniProt:

A4HW52_LEIIN

TriTrypDb:

LINF_140017150

Length:

473

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HW52

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HW52

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	3	7	PF00656	0.433
CLV_C14_Caspase3-7	47	51	PF00656	0.509
CLV_NRD_NRD_1	316	318	PF00675	0.467
CLV_NRD_NRD_1	421	423	PF00675	0.448
CLV_NRD_NRD_1	456	458	PF00675	0.428
CLV_PCSK_KEX2_1	316	318	PF00082	0.467
CLV_PCSK_KEX2_1	421	423	PF00082	0.448
CLV_PCSK_KEX2_1	456	458	PF00082	0.428
CLV_PCSK_SKI1_1	2	6	PF00082	0.441
CLV_PCSK_SKI1_1	230	234	PF00082	0.610
CLV_PCSK_SKI1_1	290	294	PF00082	0.627
CLV_PCSK_SKI1_1	317	321	PF00082	0.454
CLV_PCSK_SKI1_1	421	425	PF00082	0.451
CLV_PCSK_SKI1_1	90	94	PF00082	0.434
DEG_APCC_DBOX_1	89	97	PF00400	0.424
DEG_MDM2_SWIB_1	446	454	PF02201	0.402
DEG_Nend_UBRbox_1	1	4	PF02207	0.436
DOC_CKS1_1	206	211	PF01111	0.432
DOC_MAPK_gen_1	421	432	PF00069	0.437
DOC_PP1_RVXF_1	55	62	PF00149	0.476
DOC_PP4_FxxP_1	9	12	PF00568	0.462
DOC_USP7_MATH_1	329	333	PF00917	0.439
DOC_USP7_MATH_1	334	338	PF00917	0.432
DOC_USP7_MATH_1	355	359	PF00917	0.461
DOC_USP7_MATH_1	384	388	PF00917	0.503
DOC_USP7_MATH_1	65	69	PF00917	0.494
DOC_WW_Pin1_4	154	159	PF00397	0.561
DOC_WW_Pin1_4	205	210	PF00397	0.433
DOC_WW_Pin1_4	8	13	PF00397	0.451
LIG_14-3-3_CanoR_1	30	35	PF00244	0.527
LIG_14-3-3_CanoR_1	333	339	PF00244	0.468
LIG_14-3-3_CanoR_1	353	363	PF00244	0.390
LIG_14-3-3_CanoR_1	77	81	PF00244	0.468
LIG_BIR_III_2	185	189	PF00653	0.489
LIG_BRCT_BRCA1_1	331	335	PF00533	0.440
LIG_BRCT_BRCA1_1	372	376	PF00533	0.511
LIG_CaM_NSCaTE_8	39	46	PF13499	0.514
LIG_FHA_1	123	129	PF00498	0.444
LIG_FHA_1	14	20	PF00498	0.477
LIG_FHA_1	244	250	PF00498	0.587
LIG_FHA_1	283	289	PF00498	0.444
LIG_FHA_1	370	376	PF00498	0.515
LIG_FHA_1	436	442	PF00498	0.436
LIG_FHA_1	77	83	PF00498	0.468
LIG_FHA_2	246	252	PF00498	0.524
LIG_FHA_2	30	36	PF00498	0.523
LIG_FHA_2	81	87	PF00498	0.449
LIG_GBD_Chelix_1	447	455	PF00786	0.404
LIG_LIR_Apic_2	6	12	PF02991	0.450
LIG_LIR_Gen_1	122	132	PF02991	0.539
LIG_LIR_Gen_1	213	219	PF02991	0.477
LIG_LIR_Gen_1	332	343	PF02991	0.468
LIG_LIR_Nem_3	122	127	PF02991	0.587
LIG_LIR_Nem_3	213	217	PF02991	0.481
LIG_LIR_Nem_3	332	338	PF02991	0.454
LIG_LIR_Nem_3	37	43	PF02991	0.513
LIG_PCNA_TLS_4	2	9	PF02747	0.437
LIG_Pex14_2	236	240	PF04695	0.415
LIG_Pex14_2	446	450	PF04695	0.393
LIG_SH2_CRK	202	206	PF00017	0.413
LIG_SH2_CRK	40	44	PF00017	0.518
LIG_SH2_STAP1	245	249	PF00017	0.507
LIG_SH2_STAT5	245	248	PF00017	0.502
LIG_SH2_STAT5	283	286	PF00017	0.448
LIG_SH2_STAT5	452	455	PF00017	0.415
LIG_SH3_3	25	31	PF00018	0.443
LIG_SH3_3	9	15	PF00018	0.455
LIG_SUMO_SIM_par_1	245	251	PF11976	0.521
LIG_SUMO_SIM_par_1	78	83	PF11976	0.467
MOD_CK1_1	138	144	PF00069	0.585
MOD_CK1_1	151	157	PF00069	0.507
MOD_CK1_1	254	260	PF00069	0.585
MOD_CK1_1	370	376	PF00069	0.515
MOD_CK1_1	45	51	PF00069	0.509
MOD_CK2_1	204	210	PF00069	0.470
MOD_CK2_1	245	251	PF00069	0.521
MOD_CK2_1	258	264	PF00069	0.501
MOD_GlcNHglycan	138	141	PF01048	0.585
MOD_GlcNHglycan	149	153	PF01048	0.518
MOD_GlcNHglycan	169	172	PF01048	0.464
MOD_GlcNHglycan	253	256	PF01048	0.581
MOD_GlcNHglycan	270	273	PF01048	0.419
MOD_GlcNHglycan	278	281	PF01048	0.413
MOD_GlcNHglycan	300	304	PF01048	0.517
MOD_GlcNHglycan	357	360	PF01048	0.492
MOD_GlcNHglycan	386	389	PF01048	0.525
MOD_GlcNHglycan	406	409	PF01048	0.410
MOD_GlcNHglycan	467	471	PF01048	0.535
MOD_GSK3_1	163	170	PF00069	0.670
MOD_GSK3_1	215	222	PF00069	0.411
MOD_GSK3_1	254	261	PF00069	0.592
MOD_GSK3_1	299	306	PF00069	0.514
MOD_GSK3_1	30	37	PF00069	0.522
MOD_GSK3_1	367	374	PF00069	0.521
MOD_GSK3_1	466	473	PF00069	0.541
MOD_GSK3_1	76	83	PF00069	0.470
MOD_NEK2_1	113	118	PF00069	0.379
MOD_NEK2_1	167	172	PF00069	0.728
MOD_NEK2_1	219	224	PF00069	0.433
MOD_NEK2_1	299	304	PF00069	0.515
MOD_NEK2_1	348	353	PF00069	0.436
MOD_NEK2_1	369	374	PF00069	0.516
MOD_NEK2_1	404	409	PF00069	0.498
MOD_NEK2_1	432	437	PF00069	0.430
MOD_NEK2_2	245	250	PF00069	0.516
MOD_NEK2_2	303	308	PF00069	0.507
MOD_PIKK_1	219	225	PF00454	0.433
MOD_PK_1	394	400	PF00069	0.523
MOD_PKA_1	421	427	PF00069	0.448
MOD_PKA_2	219	225	PF00069	0.433
MOD_PKA_2	29	35	PF00069	0.525
MOD_PKA_2	421	427	PF00069	0.448
MOD_PKA_2	76	82	PF00069	0.468
MOD_Plk_1	215	221	PF00069	0.414
MOD_Plk_1	394	400	PF00069	0.523
MOD_Plk_4	303	309	PF00069	0.507
MOD_Plk_4	34	40	PF00069	0.624
MOD_Plk_4	371	377	PF00069	0.508
MOD_Plk_4	76	82	PF00069	0.468
MOD_ProDKin_1	154	160	PF00069	0.560
MOD_ProDKin_1	205	211	PF00069	0.431
MOD_ProDKin_1	8	14	PF00069	0.449
MOD_SUMO_rev_2	129	138	PF00179	0.556
TRG_DiLeu_BaLyEn_6	323	328	PF01217	0.422
TRG_ENDOCYTIC_2	202	205	PF00928	0.417
TRG_ENDOCYTIC_2	40	43	PF00928	0.514
TRG_ENDOCYTIC_2	452	455	PF00928	0.415
TRG_ER_diArg_1	228	231	PF00400	0.389
TRG_ER_diArg_1	421	423	PF00400	0.448
TRG_ER_diArg_1	455	457	PF00400	0.421
TRG_Pf-PMV_PEXEL_1	2	6	PF00026	0.441

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WT36	Leishmania donovani	100%	100%