Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4HVV1_LEIIN

TriTrypDb:

LINF_140005800

Length:

384

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HVV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVV1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	123	125	PF00675	0.743
CLV_NRD_NRD_1	142	144	PF00675	0.722
CLV_NRD_NRD_1	163	165	PF00675	0.802
CLV_NRD_NRD_1	196	198	PF00675	0.625
CLV_NRD_NRD_1	206	208	PF00675	0.561
CLV_NRD_NRD_1	254	256	PF00675	0.735
CLV_NRD_NRD_1	346	348	PF00675	0.677
CLV_PCSK_FUR_1	252	256	PF00082	0.637
CLV_PCSK_KEX2_1	162	164	PF00082	0.718
CLV_PCSK_KEX2_1	196	198	PF00082	0.625
CLV_PCSK_KEX2_1	206	208	PF00082	0.561
CLV_PCSK_KEX2_1	254	256	PF00082	0.732
CLV_PCSK_KEX2_1	346	348	PF00082	0.677
CLV_PCSK_PC1ET2_1	206	208	PF00082	0.603
CLV_PCSK_SKI1_1	40	44	PF00082	0.596
CLV_Separin_Metazoa	116	120	PF03568	0.519
DEG_Nend_UBRbox_2	1	3	PF02207	0.504
DOC_CYCLIN_yCln2_LP_2	61	67	PF00134	0.604
DOC_MAPK_gen_1	162	172	PF00069	0.726
DOC_MAPK_gen_1	196	202	PF00069	0.629
DOC_MAPK_gen_1	34	43	PF00069	0.521
DOC_MAPK_MEF2A_6	163	172	PF00069	0.725
DOC_PP2B_LxvP_1	65	68	PF13499	0.615
DOC_USP7_MATH_1	137	141	PF00917	0.815
DOC_USP7_MATH_1	15	19	PF00917	0.534
DOC_USP7_MATH_1	178	182	PF00917	0.684
DOC_USP7_MATH_1	186	190	PF00917	0.546
DOC_USP7_MATH_1	225	229	PF00917	0.742
DOC_USP7_MATH_1	245	249	PF00917	0.726
DOC_USP7_MATH_1	274	278	PF00917	0.739
DOC_USP7_MATH_1	311	315	PF00917	0.809
DOC_USP7_MATH_1	96	100	PF00917	0.640
DOC_USP7_UBL2_3	144	148	PF12436	0.769
DOC_WW_Pin1_4	275	280	PF00397	0.709
DOC_WW_Pin1_4	299	304	PF00397	0.815
DOC_WW_Pin1_4	327	332	PF00397	0.790
LIG_14-3-3_CanoR_1	106	110	PF00244	0.572
LIG_14-3-3_CanoR_1	197	203	PF00244	0.653
LIG_14-3-3_CanoR_1	222	230	PF00244	0.754
LIG_14-3-3_CanoR_1	258	266	PF00244	0.833
LIG_14-3-3_CanoR_1	269	274	PF00244	0.763
LIG_14-3-3_CanoR_1	275	279	PF00244	0.556
LIG_14-3-3_CanoR_1	360	370	PF00244	0.617
LIG_Actin_WH2_2	103	121	PF00022	0.574
LIG_BIR_III_2	291	295	PF00653	0.617
LIG_FHA_1	221	227	PF00498	0.700
LIG_FHA_1	241	247	PF00498	0.735
LIG_FHA_1	268	274	PF00498	0.732
LIG_FHA_1	279	285	PF00498	0.549
LIG_FHA_1	310	316	PF00498	0.765
LIG_FHA_1	333	339	PF00498	0.716
LIG_FHA_1	363	369	PF00498	0.625
LIG_FHA_2	305	311	PF00498	0.699
LIG_Integrin_isoDGR_2	141	143	PF01839	0.727
LIG_LIR_Gen_1	102	110	PF02991	0.486
LIG_LIR_Gen_1	18	29	PF02991	0.522
LIG_LIR_Gen_1	212	219	PF02991	0.627
LIG_LIR_Gen_1	287	297	PF02991	0.695
LIG_LIR_Gen_1	30	38	PF02991	0.504
LIG_LIR_Gen_1	82	90	PF02991	0.607
LIG_LIR_Nem_3	102	107	PF02991	0.494
LIG_LIR_Nem_3	18	24	PF02991	0.507
LIG_LIR_Nem_3	212	217	PF02991	0.649
LIG_LIR_Nem_3	371	377	PF02991	0.608
LIG_LIR_Nem_3	82	86	PF02991	0.603
LIG_SH2_STAP1	32	36	PF00017	0.536
LIG_SH3_1	162	168	PF00018	0.731
LIG_SH3_2	294	299	PF14604	0.634
LIG_SH3_3	151	157	PF00018	0.763
LIG_SH3_3	162	168	PF00018	0.592
LIG_SH3_3	291	297	PF00018	0.763
LIG_SH3_3	328	334	PF00018	0.782
LIG_SH3_3	45	51	PF00018	0.542
LIG_SH3_3	61	67	PF00018	0.374
LIG_SH3_4	146	153	PF00018	0.733
LIG_TRAF2_1	265	268	PF00917	0.744
MOD_CK1_1	181	187	PF00069	0.676
MOD_CK1_1	190	196	PF00069	0.607
MOD_CK1_1	228	234	PF00069	0.699
MOD_CK1_1	261	267	PF00069	0.726
MOD_CK1_1	278	284	PF00069	0.647
MOD_CK1_1	304	310	PF00069	0.803
MOD_CK1_1	314	320	PF00069	0.790
MOD_CK1_1	332	338	PF00069	0.666
MOD_CK1_1	339	345	PF00069	0.520
MOD_CK1_1	7	13	PF00069	0.543
MOD_CK2_1	230	236	PF00069	0.679
MOD_CK2_1	245	251	PF00069	0.756
MOD_CK2_1	96	102	PF00069	0.649
MOD_Cter_Amidation	141	144	PF01082	0.727
MOD_DYRK1A_RPxSP_1	275	279	PF00069	0.729
MOD_GlcNHglycan	151	154	PF01048	0.794
MOD_GlcNHglycan	217	220	PF01048	0.587
MOD_GlcNHglycan	263	266	PF01048	0.783
MOD_GlcNHglycan	317	320	PF01048	0.782
MOD_GlcNHglycan	324	328	PF01048	0.793
MOD_GlcNHglycan	338	341	PF01048	0.591
MOD_GlcNHglycan	74	77	PF01048	0.655
MOD_GlcNHglycan	98	101	PF01048	0.586
MOD_GSK3_1	16	23	PF00069	0.507
MOD_GSK3_1	174	181	PF00069	0.679
MOD_GSK3_1	186	193	PF00069	0.600
MOD_GSK3_1	217	224	PF00069	0.696
MOD_GSK3_1	274	281	PF00069	0.680
MOD_GSK3_1	311	318	PF00069	0.796
MOD_GSK3_1	323	330	PF00069	0.782
MOD_GSK3_1	332	339	PF00069	0.654
MOD_N-GLC_1	15	20	PF02516	0.505
MOD_NEK2_1	105	110	PF00069	0.602
MOD_NEK2_1	149	154	PF00069	0.720
MOD_NEK2_1	195	200	PF00069	0.592
MOD_NEK2_1	217	222	PF00069	0.670
MOD_NEK2_1	240	245	PF00069	0.684
MOD_NEK2_1	284	289	PF00069	0.797
MOD_NEK2_1	361	366	PF00069	0.696
MOD_NEK2_1	4	9	PF00069	0.537
MOD_NEK2_2	311	316	PF00069	0.810
MOD_PIKK_1	190	196	PF00454	0.577
MOD_PIKK_1	217	223	PF00454	0.674
MOD_PIKK_1	258	264	PF00454	0.730
MOD_PKA_2	105	111	PF00069	0.580
MOD_PKA_2	195	201	PF00069	0.643
MOD_PKA_2	221	227	PF00069	0.739
MOD_PKA_2	268	274	PF00069	0.713
MOD_PKA_2	30	36	PF00069	0.534
MOD_PKA_2	72	78	PF00069	0.604
MOD_PKB_1	258	266	PF00069	0.748
MOD_Plk_1	15	21	PF00069	0.503
MOD_Plk_1	323	329	PF00069	0.782
MOD_Plk_1	370	376	PF00069	0.556
MOD_Plk_4	105	111	PF00069	0.599
MOD_Plk_4	16	22	PF00069	0.426
MOD_Plk_4	285	291	PF00069	0.798
MOD_Plk_4	4	10	PF00069	0.568
MOD_ProDKin_1	275	281	PF00069	0.708
MOD_ProDKin_1	299	305	PF00069	0.815
MOD_ProDKin_1	327	333	PF00069	0.785
TRG_DiLeu_BaLyEn_6	280	285	PF01217	0.713
TRG_ENDOCYTIC_2	21	24	PF00928	0.453
TRG_ENDOCYTIC_2	290	293	PF00928	0.796
TRG_ENDOCYTIC_2	32	35	PF00928	0.437
TRG_ER_diArg_1	162	164	PF00400	0.819
TRG_ER_diArg_1	195	197	PF00400	0.628
TRG_ER_diArg_1	252	255	PF00400	0.753
TRG_ER_diArg_1	345	347	PF00400	0.682
TRG_ER_diArg_1	354	357	PF00400	0.523
TRG_NLS_MonoExtC_3	142	147	PF00514	0.643
TRG_Pf-PMV_PEXEL_1	347	351	PF00026	0.635
TRG_Pf-PMV_PEXEL_1	55	59	PF00026	0.498

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB18	Leptomonas seymouri	51%	97%
A0A3S7WSS6	Leishmania donovani	99%	100%
A4H7H0	Leishmania braziliensis	72%	99%
C9ZT76	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	84%
E9APK3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QFX6	Leishmania major	94%	100%