Putative phosphatidylinositol 3-kinase 2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PI3-kinase family - ras-binding domain/Phosphoinositide 3-kinase C2/Phosphoinositide 3-kinase family - accessory domain (PIK domain)/Phosphatidylinositol 3- and 4-kinase - putative

Species:

Leishmania infantum

UniProt:

A4HVU4_LEIIN

TriTrypDb:

LINF_140005100

Length:

1047

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HVU4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVU4

Function

Biological processes
Term	Name	Level	Count
GO:0006793	phosphorus metabolic process	3	8
GO:0006796	phosphate-containing compound metabolic process	4	8
GO:0007165	signal transduction	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016310	phosphorylation	5	8
GO:0035556	intracellular signal transduction	3	8
GO:0044237	cellular metabolic process	2	8
GO:0048015	phosphatidylinositol-mediated signaling	5	8
GO:0048017	inositol lipid-mediated signaling	4	8
GO:0050789	regulation of biological process	2	8
GO:0050794	regulation of cellular process	3	8
GO:0065007	biological regulation	1	8
GO:0006629	lipid metabolic process	3	5
GO:0006644	phospholipid metabolic process	4	5
GO:0006650	glycerophospholipid metabolic process	5	5
GO:0006661	phosphatidylinositol biosynthetic process	6	5
GO:0008610	lipid biosynthetic process	4	5
GO:0008654	phospholipid biosynthetic process	5	5
GO:0009058	biosynthetic process	2	5
GO:0019637	organophosphate metabolic process	3	5
GO:0044238	primary metabolic process	2	5
GO:0044249	cellular biosynthetic process	3	5
GO:0044255	cellular lipid metabolic process	3	5
GO:0045017	glycerolipid biosynthetic process	4	5
GO:0046474	glycerophospholipid biosynthetic process	5	5
GO:0046486	glycerolipid metabolic process	4	5
GO:0046488	phosphatidylinositol metabolic process	6	5
GO:0046854	phosphatidylinositol phosphate biosynthetic process	7	5
GO:0071704	organic substance metabolic process	2	5
GO:0090407	organophosphate biosynthetic process	4	5
GO:1901576	organic substance biosynthetic process	3	5

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003824	catalytic activity	1	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0016301	kinase activity	4	8
GO:0016303	1-phosphatidylinositol-3-kinase activity	6	3
GO:0016740	transferase activity	2	8
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	8
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	3
GO:0017076	purine nucleotide binding	4	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035004	phosphatidylinositol 3-kinase activity	5	3
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0052742	phosphatidylinositol kinase activity	5	3
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8
GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	6	1
GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	6	1
GO:0052813	phosphatidylinositol bisphosphate kinase activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	154	158	PF00656	0.463
CLV_C14_Caspase3-7	277	281	PF00656	0.463
CLV_C14_Caspase3-7	601	605	PF00656	0.287
CLV_C14_Caspase3-7	807	811	PF00656	0.246
CLV_NRD_NRD_1	178	180	PF00675	0.551
CLV_NRD_NRD_1	43	45	PF00675	0.589
CLV_NRD_NRD_1	500	502	PF00675	0.564
CLV_NRD_NRD_1	507	509	PF00675	0.541
CLV_NRD_NRD_1	589	591	PF00675	0.537
CLV_NRD_NRD_1	655	657	PF00675	0.464
CLV_NRD_NRD_1	85	87	PF00675	0.583
CLV_NRD_NRD_1	851	853	PF00675	0.467
CLV_NRD_NRD_1	976	978	PF00675	0.218
CLV_NRD_NRD_1	98	100	PF00675	0.428
CLV_PCSK_KEX2_1	177	179	PF00082	0.564
CLV_PCSK_KEX2_1	243	245	PF00082	0.481
CLV_PCSK_KEX2_1	43	45	PF00082	0.560
CLV_PCSK_KEX2_1	500	502	PF00082	0.552
CLV_PCSK_KEX2_1	507	509	PF00082	0.557
CLV_PCSK_KEX2_1	533	535	PF00082	0.446
CLV_PCSK_KEX2_1	589	591	PF00082	0.519
CLV_PCSK_KEX2_1	655	657	PF00082	0.446
CLV_PCSK_KEX2_1	694	696	PF00082	0.450
CLV_PCSK_KEX2_1	85	87	PF00082	0.602
CLV_PCSK_KEX2_1	851	853	PF00082	0.537
CLV_PCSK_KEX2_1	937	939	PF00082	0.251
CLV_PCSK_KEX2_1	976	978	PF00082	0.218
CLV_PCSK_KEX2_1	98	100	PF00082	0.449
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.481
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.540
CLV_PCSK_PC1ET2_1	533	535	PF00082	0.446
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.519
CLV_PCSK_PC1ET2_1	937	939	PF00082	0.251
CLV_PCSK_PC7_1	173	179	PF00082	0.552
CLV_PCSK_PC7_1	651	657	PF00082	0.446
CLV_PCSK_SKI1_1	1007	1011	PF00082	0.284
CLV_PCSK_SKI1_1	1035	1039	PF00082	0.322
CLV_PCSK_SKI1_1	122	126	PF00082	0.600
CLV_PCSK_SKI1_1	254	258	PF00082	0.547
CLV_PCSK_SKI1_1	31	35	PF00082	0.666
CLV_PCSK_SKI1_1	385	389	PF00082	0.428
CLV_PCSK_SKI1_1	405	409	PF00082	0.370
CLV_PCSK_SKI1_1	489	493	PF00082	0.535
CLV_PCSK_SKI1_1	530	534	PF00082	0.446
CLV_PCSK_SKI1_1	549	553	PF00082	0.446
CLV_PCSK_SKI1_1	556	560	PF00082	0.452
CLV_PCSK_SKI1_1	651	655	PF00082	0.446
CLV_PCSK_SKI1_1	677	681	PF00082	0.537
CLV_PCSK_SKI1_1	714	718	PF00082	0.568
DEG_APCC_DBOX_1	42	50	PF00400	0.387
DEG_APCC_DBOX_1	731	739	PF00400	0.287
DEG_APCC_DBOX_1	796	804	PF00400	0.246
DEG_SPOP_SBC_1	394	398	PF00917	0.337
DOC_ANK_TNKS_1	461	468	PF00023	0.319
DOC_CKS1_1	944	949	PF01111	0.446
DOC_CYCLIN_RxL_1	382	392	PF00134	0.264
DOC_CYCLIN_RxL_1	54	65	PF00134	0.374
DOC_CYCLIN_RxL_1	645	657	PF00134	0.246
DOC_MAPK_gen_1	243	251	PF00069	0.281
DOC_MAPK_gen_1	460	468	PF00069	0.349
DOC_MAPK_gen_1	768	776	PF00069	0.276
DOC_MAPK_MEF2A_6	139	146	PF00069	0.405
DOC_MAPK_MEF2A_6	206	215	PF00069	0.281
DOC_MAPK_MEF2A_6	243	251	PF00069	0.319
DOC_MAPK_MEF2A_6	768	776	PF00069	0.294
DOC_MAPK_MEF2A_6	797	805	PF00069	0.261
DOC_MAPK_MEF2A_6	814	822	PF00069	0.193
DOC_MAPK_NFAT4_5	139	147	PF00069	0.411
DOC_MAPK_NFAT4_5	244	252	PF00069	0.281
DOC_PP1_RVXF_1	363	369	PF00149	0.268
DOC_PP1_RVXF_1	386	392	PF00149	0.310
DOC_PP1_RVXF_1	487	494	PF00149	0.376
DOC_PP1_RVXF_1	547	554	PF00149	0.264
DOC_PP1_RVXF_1	55	62	PF00149	0.359
DOC_PP1_RVXF_1	735	741	PF00149	0.320
DOC_PP2B_LxvP_1	7	10	PF13499	0.453
DOC_PP2B_PxIxI_1	210	216	PF00149	0.281
DOC_PP4_FxxP_1	132	135	PF00568	0.329
DOC_PP4_FxxP_1	259	262	PF00568	0.377
DOC_PP4_FxxP_1	487	490	PF00568	0.331
DOC_SPAK_OSR1_1	15	19	PF12202	0.446
DOC_USP7_MATH_1	111	115	PF00917	0.354
DOC_USP7_MATH_1	124	128	PF00917	0.299
DOC_USP7_MATH_1	274	278	PF00917	0.548
DOC_USP7_MATH_1	279	283	PF00917	0.497
DOC_USP7_MATH_1	356	360	PF00917	0.337
DOC_USP7_MATH_1	516	520	PF00917	0.399
DOC_USP7_UBL2_3	564	568	PF12436	0.287
DOC_USP7_UBL2_3	725	729	PF12436	0.310
DOC_USP7_UBL2_3	933	937	PF12436	0.446
DOC_WW_Pin1_4	207	212	PF00397	0.281
DOC_WW_Pin1_4	272	277	PF00397	0.515
DOC_WW_Pin1_4	589	594	PF00397	0.317
DOC_WW_Pin1_4	693	698	PF00397	0.319
DOC_WW_Pin1_4	943	948	PF00397	0.436
DOC_WW_Pin1_4	955	960	PF00397	0.440
LIG_14-3-3_CanoR_1	173	181	PF00244	0.428
LIG_14-3-3_CanoR_1	191	200	PF00244	0.290
LIG_14-3-3_CanoR_1	31	38	PF00244	0.459
LIG_14-3-3_CanoR_1	405	413	PF00244	0.290
LIG_14-3-3_CanoR_1	44	50	PF00244	0.260
LIG_14-3-3_CanoR_1	655	659	PF00244	0.264
LIG_14-3-3_CanoR_1	732	736	PF00244	0.328
LIG_14-3-3_CanoR_1	743	747	PF00244	0.216
LIG_14-3-3_CanoR_1	85	94	PF00244	0.419
LIG_14-3-3_CanoR_1	976	986	PF00244	0.495
LIG_Actin_WH2_2	519	535	PF00022	0.297
LIG_Actin_WH2_2	993	1009	PF00022	0.492
LIG_BIR_II_1	1	5	PF00653	0.436
LIG_BIR_III_4	1029	1033	PF00653	0.555
LIG_BRCT_BRCA1_1	325	329	PF00533	0.324
LIG_BRCT_BRCA1_1	428	432	PF00533	0.290
LIG_BRCT_BRCA1_1	766	770	PF00533	0.335
LIG_BRCT_BRCA1_1	957	961	PF00533	0.537
LIG_Clathr_ClatBox_1	576	580	PF01394	0.337
LIG_Clathr_ClatBox_1	918	922	PF01394	0.446
LIG_deltaCOP1_diTrp_1	108	112	PF00928	0.303
LIG_eIF4E_1	226	232	PF01652	0.246
LIG_eIF4E_1	582	588	PF01652	0.264
LIG_eIF4E_1	707	713	PF01652	0.261
LIG_FHA_1	1006	1012	PF00498	0.507
LIG_FHA_1	123	129	PF00498	0.344
LIG_FHA_1	208	214	PF00498	0.337
LIG_FHA_1	284	290	PF00498	0.435
LIG_FHA_1	293	299	PF00498	0.283
LIG_FHA_1	373	379	PF00498	0.271
LIG_FHA_1	396	402	PF00498	0.337
LIG_FHA_1	477	483	PF00498	0.340
LIG_FHA_1	743	749	PF00498	0.264
LIG_FHA_1	800	806	PF00498	0.246
LIG_FHA_1	895	901	PF00498	0.299
LIG_FHA_2	1013	1019	PF00498	0.478
LIG_FHA_2	182	188	PF00498	0.359
LIG_FHA_2	30	36	PF00498	0.407
LIG_FHA_2	406	412	PF00498	0.298
LIG_FHA_2	66	72	PF00498	0.332
LIG_FHA_2	678	684	PF00498	0.337
LIG_FHA_2	848	854	PF00498	0.287
LIG_FHA_2	997	1003	PF00498	0.561
LIG_IRF3_LxIS_1	306	312	PF10401	0.391
LIG_LIR_Apic_2	257	262	PF02991	0.378
LIG_LIR_Gen_1	1040	1046	PF02991	0.510
LIG_LIR_Gen_1	199	205	PF02991	0.337
LIG_LIR_Gen_1	326	337	PF02991	0.253
LIG_LIR_Gen_1	604	612	PF02991	0.264
LIG_LIR_Gen_1	784	794	PF02991	0.257
LIG_LIR_LC3C_4	246	251	PF02991	0.281
LIG_LIR_Nem_3	1020	1026	PF02991	0.544
LIG_LIR_Nem_3	1040	1044	PF02991	0.366
LIG_LIR_Nem_3	108	112	PF02991	0.325
LIG_LIR_Nem_3	325	331	PF02991	0.299
LIG_LIR_Nem_3	481	487	PF02991	0.291
LIG_LIR_Nem_3	604	610	PF02991	0.280
LIG_LIR_Nem_3	783	789	PF02991	0.297
LIG_LIR_Nem_3	922	926	PF02991	0.446
LIG_LIR_Nem_3	958	964	PF02991	0.446
LIG_MLH1_MIPbox_1	325	329	PF16413	0.324
LIG_MLH1_MIPbox_1	428	432	PF16413	0.337
LIG_PCNA_APIM_2	649	655	PF02747	0.246
LIG_PCNA_yPIPBox_3	655	668	PF02747	0.319
LIG_Pex14_1	575	579	PF04695	0.246
LIG_Pex14_1	868	872	PF04695	0.246
LIG_Pex14_2	480	484	PF04695	0.321
LIG_Pex14_2	740	744	PF04695	0.354
LIG_Pex14_2	786	790	PF04695	0.258
LIG_Pex14_2	919	923	PF04695	0.446
LIG_Pex14_2	926	930	PF04695	0.446
LIG_PTB_Apo_2	230	237	PF02174	0.228
LIG_PTB_Phospho_1	230	236	PF10480	0.228
LIG_SH2_CRK	1023	1027	PF00017	0.555
LIG_SH2_CRK	234	238	PF00017	0.281
LIG_SH2_CRK	538	542	PF00017	0.319
LIG_SH2_CRK	646	650	PF00017	0.287
LIG_SH2_CRK	825	829	PF00017	0.246
LIG_SH2_CRK	972	976	PF00017	0.486
LIG_SH2_GRB2like	105	108	PF00017	0.332
LIG_SH2_NCK_1	893	897	PF00017	0.310
LIG_SH2_PTP2	1041	1044	PF00017	0.501
LIG_SH2_SRC	1041	1044	PF00017	0.501
LIG_SH2_SRC	166	169	PF00017	0.359
LIG_SH2_SRC	224	227	PF00017	0.246
LIG_SH2_SRC	949	952	PF00017	0.519
LIG_SH2_STAP1	443	447	PF00017	0.319
LIG_SH2_STAP1	607	611	PF00017	0.298
LIG_SH2_STAP1	646	650	PF00017	0.319
LIG_SH2_STAT3	226	229	PF00017	0.319
LIG_SH2_STAT3	702	705	PF00017	0.259
LIG_SH2_STAT5	1041	1044	PF00017	0.488
LIG_SH2_STAT5	105	108	PF00017	0.332
LIG_SH2_STAT5	166	169	PF00017	0.329
LIG_SH2_STAT5	224	227	PF00017	0.264
LIG_SH2_STAT5	236	239	PF00017	0.246
LIG_SH2_STAT5	328	331	PF00017	0.268
LIG_SH2_STAT5	336	339	PF00017	0.275
LIG_SH2_STAT5	455	458	PF00017	0.326
LIG_SH2_STAT5	520	523	PF00017	0.345
LIG_SH2_STAT5	619	622	PF00017	0.292
LIG_SH2_STAT5	667	670	PF00017	0.246
LIG_SH2_STAT5	671	674	PF00017	0.246
LIG_SH2_STAT5	702	705	PF00017	0.259
LIG_SH2_STAT5	707	710	PF00017	0.260
LIG_SH2_STAT5	79	82	PF00017	0.260
LIG_SH2_STAT5	893	896	PF00017	0.299
LIG_SH2_STAT5	898	901	PF00017	0.299
LIG_SH2_STAT5	949	952	PF00017	0.456
LIG_SH2_STAT5	963	966	PF00017	0.421
LIG_SH3_2	117	122	PF14604	0.425
LIG_SH3_2	266	271	PF14604	0.343
LIG_SH3_3	114	120	PF00018	0.418
LIG_SH3_3	247	253	PF00018	0.305
LIG_SH3_3	263	269	PF00018	0.233
LIG_SH3_3	479	485	PF00018	0.337
LIG_SH3_3	488	494	PF00018	0.275
LIG_SH3_3	735	741	PF00018	0.341
LIG_SUMO_SIM_anti_2	1008	1013	PF11976	0.494
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.337
LIG_SUMO_SIM_anti_2	598	604	PF11976	0.246
LIG_SUMO_SIM_par_1	986	992	PF11976	0.446
LIG_TRAF2_1	1015	1018	PF00917	0.501
LIG_TRAF2_1	408	411	PF00917	0.263
LIG_TYR_ITIM	232	237	PF00017	0.348
LIG_TYR_ITIM	536	541	PF00017	0.400
LIG_TYR_ITIM	823	828	PF00017	0.324
LIG_UBA3_1	632	640	PF00899	0.392
LIG_UBA3_1	688	694	PF00899	0.363
LIG_UBA3_1	805	814	PF00899	0.299
MOD_CDC14_SPxK_1	696	699	PF00782	0.454
MOD_CDK_SPxK_1	693	699	PF00069	0.400
MOD_CDK_SPxxK_3	955	962	PF00069	0.400
MOD_CK1_1	169	175	PF00069	0.563
MOD_CK1_1	267	273	PF00069	0.408
MOD_CK1_1	282	288	PF00069	0.592
MOD_CK1_1	296	302	PF00069	0.474
MOD_CK1_1	50	56	PF00069	0.525
MOD_CK1_1	657	663	PF00069	0.310
MOD_CK2_1	1012	1018	PF00069	0.387
MOD_CK2_1	115	121	PF00069	0.514
MOD_CK2_1	193	199	PF00069	0.425
MOD_CK2_1	282	288	PF00069	0.639
MOD_CK2_1	29	35	PF00069	0.527
MOD_CK2_1	405	411	PF00069	0.348
MOD_CK2_1	45	51	PF00069	0.274
MOD_CK2_1	621	627	PF00069	0.299
MOD_CK2_1	65	71	PF00069	0.247
MOD_CK2_1	677	683	PF00069	0.305
MOD_CK2_1	826	832	PF00069	0.356
MOD_CK2_1	847	853	PF00069	0.400
MOD_CK2_1	87	93	PF00069	0.384
MOD_GlcNHglycan	168	171	PF01048	0.569
MOD_GlcNHglycan	195	198	PF01048	0.348
MOD_GlcNHglycan	311	314	PF01048	0.551
MOD_GlcNHglycan	494	497	PF01048	0.487
MOD_GlcNHglycan	570	573	PF01048	0.388
MOD_GlcNHglycan	646	649	PF01048	0.299
MOD_GlcNHglycan	791	794	PF01048	0.400
MOD_GlcNHglycan	815	818	PF01048	0.425
MOD_GlcNHglycan	979	982	PF01048	0.425
MOD_GSK3_1	111	118	PF00069	0.475
MOD_GSK3_1	152	159	PF00069	0.546
MOD_GSK3_1	169	176	PF00069	0.324
MOD_GSK3_1	27	34	PF00069	0.619
MOD_GSK3_1	279	286	PF00069	0.566
MOD_GSK3_1	292	299	PF00069	0.320
MOD_GSK3_1	370	377	PF00069	0.382
MOD_GSK3_1	389	396	PF00069	0.157
MOD_GSK3_1	472	479	PF00069	0.480
MOD_GSK3_1	543	550	PF00069	0.363
MOD_N-GLC_1	1012	1017	PF02516	0.458
MOD_N-GLC_1	677	682	PF02516	0.299
MOD_N-GLC_1	847	852	PF02516	0.299
MOD_N-GLC_1	87	92	PF02516	0.369
MOD_N-GLC_2	476	478	PF02516	0.516
MOD_NEK2_1	192	197	PF00069	0.434
MOD_NEK2_1	29	34	PF00069	0.552
MOD_NEK2_1	309	314	PF00069	0.528
MOD_NEK2_1	389	394	PF00069	0.311
MOD_NEK2_1	432	437	PF00069	0.356
MOD_NEK2_1	654	659	PF00069	0.299
MOD_NEK2_1	731	736	PF00069	0.504
MOD_NEK2_1	808	813	PF00069	0.299
MOD_NEK2_1	886	891	PF00069	0.299
MOD_NEK2_1	953	958	PF00069	0.387
MOD_NEK2_1	988	993	PF00069	0.309
MOD_NEK2_2	111	116	PF00069	0.443
MOD_NEK2_2	158	163	PF00069	0.494
MOD_PIKK_1	225	231	PF00454	0.372
MOD_PIKK_1	435	441	PF00454	0.425
MOD_PKA_1	937	943	PF00069	0.299
MOD_PKA_1	976	982	PF00069	0.333
MOD_PKA_2	172	178	PF00069	0.553
MOD_PKA_2	190	196	PF00069	0.321
MOD_PKA_2	264	270	PF00069	0.468
MOD_PKA_2	321	327	PF00069	0.510
MOD_PKA_2	654	660	PF00069	0.324
MOD_PKA_2	731	737	PF00069	0.419
MOD_PKA_2	742	748	PF00069	0.266
MOD_PKA_2	937	943	PF00069	0.299
MOD_PKA_2	976	982	PF00069	0.310
MOD_Plk_1	254	260	PF00069	0.436
MOD_Plk_1	322	328	PF00069	0.455
MOD_Plk_1	547	553	PF00069	0.366
MOD_Plk_1	677	683	PF00069	0.300
MOD_Plk_2-3	199	205	PF00069	0.348
MOD_Plk_2-3	621	627	PF00069	0.400
MOD_Plk_2-3	996	1002	PF00069	0.466
MOD_Plk_4	254	260	PF00069	0.404
MOD_Plk_4	323	329	PF00069	0.423
MOD_Plk_4	426	432	PF00069	0.449
MOD_Plk_4	516	522	PF00069	0.427
MOD_Plk_4	547	553	PF00069	0.457
MOD_Plk_4	808	814	PF00069	0.299
MOD_Plk_4	894	900	PF00069	0.299
MOD_Plk_4	914	920	PF00069	0.115
MOD_ProDKin_1	207	213	PF00069	0.348
MOD_ProDKin_1	272	278	PF00069	0.675
MOD_ProDKin_1	589	595	PF00069	0.397
MOD_ProDKin_1	693	699	PF00069	0.400
MOD_ProDKin_1	943	949	PF00069	0.285
MOD_ProDKin_1	955	961	PF00069	0.290
MOD_SUMO_for_1	316	319	PF00179	0.410
MOD_SUMO_for_1	639	642	PF00179	0.299
MOD_SUMO_for_1	936	939	PF00179	0.299
MOD_SUMO_rev_2	102	112	PF00179	0.437
MOD_SUMO_rev_2	246	256	PF00179	0.425
MOD_SUMO_rev_2	381	389	PF00179	0.293
MOD_SUMO_rev_2	545	551	PF00179	0.422
MOD_SUMO_rev_2	758	765	PF00179	0.462
TRG_DiLeu_BaEn_1	583	588	PF01217	0.324
TRG_DiLeu_BaEn_1	683	688	PF01217	0.299
TRG_DiLeu_BaEn_2	938	944	PF01217	0.299
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.440
TRG_DiLeu_BaLyEn_6	227	232	PF01217	0.204
TRG_DiLeu_BaLyEn_6	54	59	PF01217	0.436
TRG_ENDOCYTIC_2	1023	1026	PF00928	0.441
TRG_ENDOCYTIC_2	1041	1044	PF00928	0.226
TRG_ENDOCYTIC_2	234	237	PF00928	0.348
TRG_ENDOCYTIC_2	328	331	PF00928	0.329
TRG_ENDOCYTIC_2	538	541	PF00928	0.400
TRG_ENDOCYTIC_2	555	558	PF00928	0.400
TRG_ENDOCYTIC_2	607	610	PF00928	0.356
TRG_ENDOCYTIC_2	646	649	PF00928	0.356
TRG_ENDOCYTIC_2	825	828	PF00928	0.313
TRG_ENDOCYTIC_2	972	975	PF00928	0.362
TRG_ER_diArg_1	177	179	PF00400	0.464
TRG_ER_diArg_1	3	6	PF00400	0.587
TRG_ER_diArg_1	588	590	PF00400	0.425
TRG_ER_diArg_1	654	656	PF00400	0.324
TRG_ER_diArg_1	85	87	PF00400	0.510
TRG_ER_diArg_1	97	99	PF00400	0.311
TRG_ER_diArg_1	975	977	PF00400	0.259
TRG_NES_CRM1_1	1001	1016	PF08389	0.362
TRG_NES_CRM1_1	527	539	PF08389	0.425
TRG_NES_CRM1_1	627	642	PF08389	0.324
TRG_NES_CRM1_1	794	807	PF08389	0.299
TRG_Pf-PMV_PEXEL_1	1035	1040	PF00026	0.375
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.440
TRG_Pf-PMV_PEXEL_1	31	35	PF00026	0.523
TRG_Pf-PMV_PEXEL_1	36	40	PF00026	0.439
TRG_Pf-PMV_PEXEL_1	534	539	PF00026	0.299

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K344	Rattus norvegicus	33%	98%
A0A0N1I4K0	Leptomonas seymouri	73%	100%
A0A1X0NPD0	Trypanosomatidae	55%	99%
A0A3R7MRK8	Trypanosoma rangeli	51%	99%
A0A3S7WSQ8	Leishmania donovani	100%	100%
E9APJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
O00329	Homo sapiens	33%	100%
O02697	Sus scrofa	33%	95%
O35904	Mus musculus	34%	100%
P0C5E7	Caenorhabditis briggsae	28%	90%
P32871	Bos taurus	33%	98%
P42336	Homo sapiens	33%	98%
P42337	Mus musculus	33%	98%
P42338	Homo sapiens	33%	98%
P48736	Homo sapiens	34%	95%
P54673	Dictyostelium discoideum	37%	67%
Q8BTI9	Mus musculus	33%	98%
Q94125	Caenorhabditis elegans	29%	89%
Q9JHG7	Mus musculus	34%	95%
Q9Z1L0	Rattus norvegicus	33%	98%
V5AXQ0	Trypanosoma cruzi	52%	99%