HECT domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Protein:

Gene product:

SPRY domain/HECT-domain (ubiquitin-transferase) - putative

Species:

Leishmania infantum

UniProt:

A4HVS4_LEIIN

TriTrypDb:

LINF_130020100

Length:

195


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4HVS4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVS4

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004842	ubiquitin-protein transferase activity	4	2
GO:0016740	transferase activity	2	2
GO:0019787	ubiquitin-like protein transferase activity	3	2
GO:0140096	catalytic activity, acting on a protein	2	2


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	146	150	PF00082	0.199
DOC_CYCLIN_RxL_1	143	152	PF00134	0.199
DOC_CYCLIN_yCln2_LP_2	86	92	PF00134	0.475
DOC_PP1_RVXF_1	144	150	PF00149	0.199
DOC_PP2B_LxvP_1	132	135	PF13499	0.199
DOC_PP4_FxxP_1	46	49	PF00568	0.463
DOC_PP4_MxPP_1	57	60	PF00568	0.444
DOC_USP7_MATH_1	123	127	PF00917	0.199
DOC_USP7_MATH_1	178	182	PF00917	0.420
DOC_WW_Pin1_4	37	42	PF00397	0.462
DOC_WW_Pin1_4	44	49	PF00397	0.468
DOC_WW_Pin1_4	85	90	PF00397	0.475
LIG_14-3-3_CanoR_1	12	18	PF00244	0.463
LIG_14-3-3_CanoR_1	179	188	PF00244	0.408
LIG_14-3-3_CanoR_1	19	24	PF00244	0.468
LIG_BRCT_BRCA1_1	125	129	PF00533	0.199
LIG_Clathr_ClatBox_1	148	152	PF01394	0.199
LIG_FHA_1	13	19	PF00498	0.460
LIG_LIR_Gen_1	185	194	PF02991	0.376
LIG_LIR_Nem_3	126	132	PF02991	0.199
LIG_LIR_Nem_3	185	191	PF02991	0.381
LIG_MYND_1	61	65	PF01753	0.454
LIG_SH3_3	35	41	PF00018	0.473
LIG_SH3_3	45	51	PF00018	0.460
LIG_SH3_3	55	61	PF00018	0.450
LIG_TRAF2_1	169	172	PF00917	0.448
MOD_CK1_1	138	144	PF00069	0.199
MOD_CK1_1	26	32	PF00069	0.498
MOD_CK1_1	85	91	PF00069	0.476
MOD_CK2_1	178	184	PF00069	0.415
MOD_GlcNHglycan	73	76	PF01048	0.483
MOD_GSK3_1	19	26	PF00069	0.472
MOD_GSK3_1	27	34	PF00069	0.498
MOD_GSK3_1	73	80	PF00069	0.482
MOD_NEK2_1	23	28	PF00069	0.484
MOD_PKA_2	178	184	PF00069	0.415
MOD_PKA_2	26	32	PF00069	0.498
MOD_PKA_2	71	77	PF00069	0.486
MOD_Plk_1	112	118	PF00069	0.199
MOD_Plk_1	189	195	PF00069	0.364
MOD_Plk_4	13	19	PF00069	0.460
MOD_Plk_4	138	144	PF00069	0.199
MOD_Plk_4	82	88	PF00069	0.474
MOD_ProDKin_1	37	43	PF00069	0.464
MOD_ProDKin_1	44	50	PF00069	0.463
MOD_ProDKin_1	85	91	PF00069	0.476
TRG_AP2beta_CARGO_1	185	195	PF09066	0.377
TRG_NES_CRM1_1	145	160	PF08389	0.199