Complex1_LYR_dom domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Complex1 LYR-like/Complex 1 protein (LYR family) - putative

Species:

Leishmania infantum

UniProt:

A4HVQ8_LEIIN

TriTrypDb:

LINF_130018200

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HVQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVQ8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.390
CLV_NRD_NRD_1	121	123	PF00675	0.510
CLV_NRD_NRD_1	186	188	PF00675	0.513
CLV_NRD_NRD_1	46	48	PF00675	0.291
CLV_NRD_NRD_1	9	11	PF00675	0.492
CLV_PCSK_FUR_1	44	48	PF00082	0.325
CLV_PCSK_KEX2_1	121	123	PF00082	0.583
CLV_PCSK_KEX2_1	186	188	PF00082	0.513
CLV_PCSK_KEX2_1	46	48	PF00082	0.291
CLV_PCSK_KEX2_1	9	11	PF00082	0.636
CLV_PCSK_SKI1_1	157	161	PF00082	0.525
CLV_PCSK_SKI1_1	186	190	PF00082	0.507
CLV_PCSK_SKI1_1	32	36	PF00082	0.349
CLV_PCSK_SKI1_1	74	78	PF00082	0.323
CLV_PCSK_SKI1_1	83	87	PF00082	0.291
DEG_Nend_Nbox_1	1	3	PF02207	0.619
DOC_PP4_FxxP_1	58	61	PF00568	0.291
DOC_USP7_MATH_1	42	46	PF00917	0.298
DOC_USP7_UBL2_3	153	157	PF12436	0.534
LIG_14-3-3_CanoR_1	130	139	PF00244	0.560
LIG_14-3-3_CanoR_1	29	35	PF00244	0.401
LIG_14-3-3_CanoR_1	3	7	PF00244	0.573
LIG_14-3-3_CanoR_1	55	59	PF00244	0.389
LIG_FHA_1	131	137	PF00498	0.442
LIG_FHA_1	2	8	PF00498	0.625
LIG_FHA_1	49	55	PF00498	0.335
LIG_FHA_2	55	61	PF00498	0.325
LIG_FHA_2	85	91	PF00498	0.319
LIG_FHA_2	9	15	PF00498	0.435
LIG_LIR_Apic_2	56	61	PF02991	0.324
LIG_LIR_Nem_3	141	146	PF02991	0.488
LIG_LIR_Nem_3	70	76	PF02991	0.325
LIG_Pex14_2	184	188	PF04695	0.518
LIG_Pex14_2	192	196	PF04695	0.517
LIG_REV1ctd_RIR_1	181	191	PF16727	0.546
LIG_SH2_CRK	31	35	PF00017	0.291
LIG_SH2_CRK	73	77	PF00017	0.366
LIG_SH2_GRB2like	143	146	PF00017	0.511
LIG_SH2_STAP1	88	92	PF00017	0.325
LIG_SH2_STAT3	22	25	PF00017	0.505
LIG_SH2_STAT5	107	110	PF00017	0.385
LIG_SH3_3	173	179	PF00018	0.559
LIG_TYR_ITIM	71	76	PF00017	0.366
MOD_CK1_1	84	90	PF00069	0.385
MOD_CK2_1	8	14	PF00069	0.427
MOD_CK2_1	84	90	PF00069	0.427
MOD_CK2_1	94	100	PF00069	0.255
MOD_GSK3_1	130	137	PF00069	0.474
MOD_NEK2_1	1	6	PF00069	0.643
MOD_NEK2_1	139	144	PF00069	0.499
MOD_NEK2_1	30	35	PF00069	0.414
MOD_PK_1	81	87	PF00069	0.385
MOD_PKA_2	2	8	PF00069	0.567
MOD_PKA_2	54	60	PF00069	0.385
MOD_Plk_2-3	48	54	PF00069	0.291
MOD_Plk_2-3	64	70	PF00069	0.291
MOD_Plk_4	139	145	PF00069	0.497
MOD_Plk_4	2	8	PF00069	0.574
MOD_SUMO_rev_2	109	117	PF00179	0.400
MOD_SUMO_rev_2	134	142	PF00179	0.534
TRG_DiLeu_BaLyEn_6	71	76	PF01217	0.307
TRG_ENDOCYTIC_2	143	146	PF00928	0.489
TRG_ENDOCYTIC_2	31	34	PF00928	0.291
TRG_ENDOCYTIC_2	73	76	PF00928	0.366
TRG_ER_diArg_1	120	122	PF00400	0.360
TRG_ER_diArg_1	166	169	PF00400	0.491
TRG_ER_diArg_1	185	187	PF00400	0.511
TRG_ER_diArg_1	43	46	PF00400	0.336

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7Q9	Leptomonas seymouri	80%	100%
A0A0S4JJ94	Bodo saltans	66%	100%
A0A3Q8I9K5	Leishmania donovani	100%	100%
A4H7B3	Leishmania braziliensis	92%	100%
D0A6I2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	87%
E9APF4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4QG24	Leishmania major	97%	100%