Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HVQ3_LEIIN

TriTrypDb:

LINF_130017600

Length:

150

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HVQ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVQ3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	123	125	PF00675	0.711
CLV_NRD_NRD_1	67	69	PF00675	0.701
CLV_PCSK_FUR_1	26	30	PF00082	0.462
CLV_PCSK_KEX2_1	109	111	PF00082	0.726
CLV_PCSK_KEX2_1	148	150	PF00082	0.719
CLV_PCSK_KEX2_1	28	30	PF00082	0.519
CLV_PCSK_KEX2_1	67	69	PF00082	0.676
CLV_PCSK_PC1ET2_1	109	111	PF00082	0.726
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.719
CLV_PCSK_PC1ET2_1	28	30	PF00082	0.450
CLV_PCSK_PC7_1	63	69	PF00082	0.676
CLV_PCSK_SKI1_1	67	71	PF00082	0.658
DOC_CKS1_1	10	15	PF01111	0.680
DOC_CKS1_1	62	67	PF01111	0.466
DOC_CYCLIN_RxL_1	63	72	PF00134	0.555
DOC_WW_Pin1_4	127	132	PF00397	0.471
DOC_WW_Pin1_4	61	66	PF00397	0.457
DOC_WW_Pin1_4	9	14	PF00397	0.685
LIG_14-3-3_CanoR_1	124	131	PF00244	0.562
LIG_14-3-3_CanoR_1	26	32	PF00244	0.656
LIG_14-3-3_CanoR_1	89	94	PF00244	0.511
LIG_Clathr_ClatBox_1	39	43	PF01394	0.507
LIG_FHA_1	128	134	PF00498	0.520
LIG_FHA_1	16	22	PF00498	0.702
LIG_SH2_STAT5	58	61	PF00017	0.522
LIG_SH3_3	11	17	PF00018	0.642
LIG_SH3_3	59	65	PF00018	0.557
LIG_SUMO_SIM_par_1	38	43	PF11976	0.503
LIG_TYR_ITIM	55	60	PF00017	0.311
MOD_CDK_SPxK_1	61	67	PF00069	0.463
MOD_CDK_SPxxK_3	61	68	PF00069	0.467
MOD_CK1_1	105	111	PF00069	0.459
MOD_CK1_1	123	129	PF00069	0.498
MOD_CK1_1	135	141	PF00069	0.485
MOD_CK1_1	84	90	PF00069	0.577
MOD_CK1_1	98	104	PF00069	0.418
MOD_CK2_1	126	132	PF00069	0.560
MOD_CK2_1	88	94	PF00069	0.547
MOD_Cter_Amidation	65	68	PF01082	0.680
MOD_GlcNHglycan	134	137	PF01048	0.716
MOD_GSK3_1	123	130	PF00069	0.577
MOD_GSK3_1	138	145	PF00069	0.396
MOD_GSK3_1	77	84	PF00069	0.481
MOD_GSK3_1	85	92	PF00069	0.471
MOD_GSK3_1	98	105	PF00069	0.445
MOD_LATS_1	140	146	PF00433	0.450
MOD_NEK2_1	95	100	PF00069	0.504
MOD_PK_1	89	95	PF00069	0.470
MOD_PKA_2	123	129	PF00069	0.523
MOD_PKA_2	88	94	PF00069	0.536
MOD_PKA_2	98	104	PF00069	0.478
MOD_ProDKin_1	127	133	PF00069	0.472
MOD_ProDKin_1	61	67	PF00069	0.463
MOD_ProDKin_1	9	15	PF00069	0.683
TRG_DiLeu_BaLyEn_6	65	70	PF01217	0.557
TRG_ENDOCYTIC_2	57	60	PF00928	0.365
TRG_ER_diArg_1	67	69	PF00400	0.425
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.767

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P887	Leptomonas seymouri	48%	100%
A0A3S5H6P6	Leishmania donovani	99%	100%
A4H7A8	Leishmania braziliensis	67%	97%
Q4QG29	Leishmania major	87%	100%