LeishMANIAdb
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Sister chromatid cohesion protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Sister chromatid cohesion protein
Gene product:
Sister chromatid cohesion C-terminus - putative
Species:
Leishmania infantum
UniProt:
A4HVG3_LEIIN
TriTrypDb:
LINF_130008900
Length:
2023

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 10
GO:0043226 organelle 2 10
GO:0043227 membrane-bounded organelle 3 10
GO:0043229 intracellular organelle 3 10
GO:0043231 intracellular membrane-bounded organelle 4 10
GO:0110165 cellular anatomical entity 1 10
GO:0032116 SMC loading complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0090694 Scc2-Scc4 cohesin loading complex 4 1
GO:0140513 nuclear protein-containing complex 2 1

Expansion

Sequence features

A4HVG3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HVG3

Function

Biological processes
Term Name Level Count
GO:0008104 protein localization 4 11
GO:0009987 cellular process 1 11
GO:0010468 regulation of gene expression 5 11
GO:0019222 regulation of metabolic process 3 11
GO:0022402 cell cycle process 2 11
GO:0033036 macromolecule localization 2 11
GO:0033365 protein localization to organelle 5 11
GO:0034502 protein localization to chromosome 6 11
GO:0050789 regulation of biological process 2 11
GO:0051179 localization 1 11
GO:0051641 cellular localization 2 11
GO:0060255 regulation of macromolecule metabolic process 4 11
GO:0061780 mitotic cohesin loading 4 11
GO:0065007 biological regulation 1 11
GO:0070727 cellular macromolecule localization 3 11
GO:0071168 protein localization to chromatin 7 11
GO:0071921 cohesin loading 3 11
GO:1903047 mitotic cell cycle process 3 11
GO:0000724 double-strand break repair via homologous recombination 7 1
GO:0000725 recombinational repair 6 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006310 DNA recombination 5 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0008152 metabolic process 1 1
GO:0033554 cellular response to stress 3 1
GO:0034085 establishment of sister chromatid cohesion 3 1
GO:0034087 establishment of mitotic sister chromatid cohesion 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0045184 establishment of protein localization 3 1
GO:0046483 heterocycle metabolic process 3 1
GO:0050896 response to stimulus 1 1
GO:0051234 establishment of localization 2 1
GO:0051716 cellular response to stimulus 2 1
GO:0070199 establishment of protein localization to chromosome 5 1
GO:0071169 establishment of protein localization to chromatin 6 1
GO:0071704 organic substance metabolic process 2 1
GO:0072594 establishment of protein localization to organelle 4 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1990414 replication-born double-strand break repair via sister chromatid exchange 8 1
Molecular functions
Term Name Level Count
GO:0003682 chromatin binding 2 11
GO:0005488 binding 1 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1061 1065 PF00656 0.608
CLV_C14_Caspase3-7 116 120 PF00656 0.759
CLV_C14_Caspase3-7 1496 1500 PF00656 0.621
CLV_C14_Caspase3-7 1671 1675 PF00656 0.441
CLV_C14_Caspase3-7 1804 1808 PF00656 0.654
CLV_C14_Caspase3-7 1983 1987 PF00656 0.713
CLV_C14_Caspase3-7 287 291 PF00656 0.574
CLV_C14_Caspase3-7 451 455 PF00656 0.511
CLV_C14_Caspase3-7 818 822 PF00656 0.664
CLV_NRD_NRD_1 1056 1058 PF00675 0.454
CLV_NRD_NRD_1 1136 1138 PF00675 0.642
CLV_NRD_NRD_1 1460 1462 PF00675 0.633
CLV_NRD_NRD_1 164 166 PF00675 0.772
CLV_NRD_NRD_1 1828 1830 PF00675 0.367
CLV_NRD_NRD_1 1962 1964 PF00675 0.755
CLV_NRD_NRD_1 2014 2016 PF00675 0.813
CLV_NRD_NRD_1 213 215 PF00675 0.666
CLV_NRD_NRD_1 247 249 PF00675 0.726
CLV_NRD_NRD_1 621 623 PF00675 0.580
CLV_PCSK_FUR_1 162 166 PF00082 0.568
CLV_PCSK_FUR_1 1962 1966 PF00082 0.799
CLV_PCSK_FUR_1 2012 2016 PF00082 0.683
CLV_PCSK_FUR_1 211 215 PF00082 0.719
CLV_PCSK_KEX2_1 1056 1058 PF00082 0.450
CLV_PCSK_KEX2_1 1135 1137 PF00082 0.680
CLV_PCSK_KEX2_1 1508 1510 PF00082 0.730
CLV_PCSK_KEX2_1 1513 1515 PF00082 0.706
CLV_PCSK_KEX2_1 164 166 PF00082 0.734
CLV_PCSK_KEX2_1 1696 1698 PF00082 0.378
CLV_PCSK_KEX2_1 1828 1830 PF00082 0.381
CLV_PCSK_KEX2_1 1962 1964 PF00082 0.697
CLV_PCSK_KEX2_1 2012 2014 PF00082 0.816
CLV_PCSK_KEX2_1 213 215 PF00082 0.697
CLV_PCSK_KEX2_1 246 248 PF00082 0.734
CLV_PCSK_KEX2_1 621 623 PF00082 0.563
CLV_PCSK_KEX2_1 904 906 PF00082 0.512
CLV_PCSK_PC1ET2_1 1508 1510 PF00082 0.801
CLV_PCSK_PC1ET2_1 1513 1515 PF00082 0.760
CLV_PCSK_PC1ET2_1 1696 1698 PF00082 0.378
CLV_PCSK_PC1ET2_1 1964 1966 PF00082 0.717
CLV_PCSK_PC1ET2_1 904 906 PF00082 0.469
CLV_PCSK_PC7_1 1509 1515 PF00082 0.783
CLV_PCSK_SKI1_1 1052 1056 PF00082 0.464
CLV_PCSK_SKI1_1 1248 1252 PF00082 0.459
CLV_PCSK_SKI1_1 1309 1313 PF00082 0.542
CLV_PCSK_SKI1_1 1327 1331 PF00082 0.370
CLV_PCSK_SKI1_1 138 142 PF00082 0.649
CLV_PCSK_SKI1_1 1427 1431 PF00082 0.451
CLV_PCSK_SKI1_1 1461 1465 PF00082 0.593
CLV_PCSK_SKI1_1 1523 1527 PF00082 0.743
CLV_PCSK_SKI1_1 1582 1586 PF00082 0.402
CLV_PCSK_SKI1_1 1725 1729 PF00082 0.402
CLV_PCSK_SKI1_1 1829 1833 PF00082 0.366
CLV_PCSK_SKI1_1 1852 1856 PF00082 0.697
CLV_PCSK_SKI1_1 1955 1959 PF00082 0.800
CLV_PCSK_SKI1_1 27 31 PF00082 0.684
CLV_PCSK_SKI1_1 411 415 PF00082 0.371
CLV_PCSK_SKI1_1 572 576 PF00082 0.544
CLV_PCSK_SKI1_1 732 736 PF00082 0.591
CLV_PCSK_SKI1_1 764 768 PF00082 0.628
CLV_PCSK_SKI1_1 904 908 PF00082 0.425
DEG_APCC_DBOX_1 1236 1244 PF00400 0.487
DEG_APCC_DBOX_1 1308 1316 PF00400 0.534
DEG_APCC_DBOX_1 153 161 PF00400 0.712
DEG_APCC_DBOX_1 186 194 PF00400 0.719
DEG_APCC_DBOX_1 541 549 PF00400 0.547
DEG_APCC_DBOX_1 731 739 PF00400 0.599
DEG_APCC_DBOX_1 874 882 PF00400 0.465
DEG_MDM2_SWIB_1 1054 1062 PF02201 0.507
DEG_SCF_TRCP1_1 306 311 PF00400 0.584
DEG_SPOP_SBC_1 170 174 PF00917 0.701
DEG_SPOP_SBC_1 1735 1739 PF00917 0.480
DEG_SPOP_SBC_1 223 227 PF00917 0.783
DEG_SPOP_SBC_1 253 257 PF00917 0.760
DEG_SPOP_SBC_1 765 769 PF00917 0.532
DOC_CKS1_1 1016 1021 PF01111 0.593
DOC_CKS1_1 1932 1937 PF01111 0.581
DOC_CYCLIN_RxL_1 1028 1039 PF00134 0.475
DOC_CYCLIN_RxL_1 1306 1314 PF00134 0.562
DOC_CYCLIN_RxL_1 1324 1334 PF00134 0.394
DOC_CYCLIN_RxL_1 24 31 PF00134 0.719
DOC_CYCLIN_RxL_1 480 491 PF00134 0.563
DOC_CYCLIN_RxL_1 684 692 PF00134 0.466
DOC_CYCLIN_yCln2_LP_2 1592 1595 PF00134 0.319
DOC_CYCLIN_yCln2_LP_2 1746 1752 PF00134 0.480
DOC_CYCLIN_yCln2_LP_2 739 745 PF00134 0.541
DOC_MAPK_DCC_7 1234 1243 PF00069 0.584
DOC_MAPK_DCC_7 938 948 PF00069 0.439
DOC_MAPK_gen_1 1056 1062 PF00069 0.539
DOC_MAPK_gen_1 1234 1243 PF00069 0.560
DOC_MAPK_gen_1 1282 1291 PF00069 0.530
DOC_MAPK_gen_1 1815 1824 PF00069 0.510
DOC_MAPK_gen_1 408 418 PF00069 0.527
DOC_MAPK_gen_1 542 550 PF00069 0.511
DOC_MAPK_gen_1 938 946 PF00069 0.398
DOC_MAPK_HePTP_8 1394 1406 PF00069 0.405
DOC_MAPK_JIP1_4 687 693 PF00069 0.443
DOC_MAPK_MEF2A_6 1078 1085 PF00069 0.461
DOC_MAPK_MEF2A_6 1234 1243 PF00069 0.601
DOC_MAPK_MEF2A_6 1397 1406 PF00069 0.396
DOC_MAPK_MEF2A_6 1577 1585 PF00069 0.402
DOC_MAPK_MEF2A_6 411 420 PF00069 0.560
DOC_MAPK_MEF2A_6 542 550 PF00069 0.521
DOC_MAPK_MEF2A_6 572 581 PF00069 0.494
DOC_MAPK_MEF2A_6 889 898 PF00069 0.585
DOC_MAPK_MEF2A_6 940 948 PF00069 0.411
DOC_MAPK_NFAT4_5 572 580 PF00069 0.496
DOC_PP2B_LxvP_1 1233 1236 PF13499 0.503
DOC_PP2B_LxvP_1 1498 1501 PF13499 0.631
DOC_PP2B_LxvP_1 1592 1595 PF13499 0.335
DOC_PP2B_LxvP_1 649 652 PF13499 0.560
DOC_PP2B_LxvP_1 739 742 PF13499 0.527
DOC_PP4_FxxP_1 1016 1019 PF00568 0.542
DOC_PP4_FxxP_1 32 35 PF00568 0.614
DOC_PP4_FxxP_1 707 710 PF00568 0.539
DOC_USP7_MATH_1 1065 1069 PF00917 0.676
DOC_USP7_MATH_1 1155 1159 PF00917 0.462
DOC_USP7_MATH_1 117 121 PF00917 0.710
DOC_USP7_MATH_1 1429 1433 PF00917 0.521
DOC_USP7_MATH_1 1617 1621 PF00917 0.454
DOC_USP7_MATH_1 1672 1676 PF00917 0.344
DOC_USP7_MATH_1 170 174 PF00917 0.790
DOC_USP7_MATH_1 1735 1739 PF00917 0.466
DOC_USP7_MATH_1 1766 1770 PF00917 0.447
DOC_USP7_MATH_1 18 22 PF00917 0.682
DOC_USP7_MATH_1 1806 1810 PF00917 0.598
DOC_USP7_MATH_1 1858 1862 PF00917 0.698
DOC_USP7_MATH_1 1870 1874 PF00917 0.643
DOC_USP7_MATH_1 1900 1904 PF00917 0.667
DOC_USP7_MATH_1 212 216 PF00917 0.743
DOC_USP7_MATH_1 223 227 PF00917 0.665
DOC_USP7_MATH_1 254 258 PF00917 0.748
DOC_USP7_MATH_1 304 308 PF00917 0.661
DOC_USP7_MATH_1 360 364 PF00917 0.669
DOC_USP7_MATH_1 458 462 PF00917 0.592
DOC_USP7_MATH_1 5 9 PF00917 0.760
DOC_USP7_MATH_1 507 511 PF00917 0.534
DOC_USP7_MATH_1 554 558 PF00917 0.588
DOC_USP7_MATH_1 66 70 PF00917 0.759
DOC_USP7_MATH_1 765 769 PF00917 0.639
DOC_USP7_MATH_1 772 776 PF00917 0.613
DOC_USP7_MATH_1 831 835 PF00917 0.588
DOC_USP7_UBL2_3 1048 1052 PF12436 0.569
DOC_WW_Pin1_4 1015 1020 PF00397 0.585
DOC_WW_Pin1_4 1034 1039 PF00397 0.285
DOC_WW_Pin1_4 1120 1125 PF00397 0.717
DOC_WW_Pin1_4 1206 1211 PF00397 0.572
DOC_WW_Pin1_4 1536 1541 PF00397 0.735
DOC_WW_Pin1_4 1568 1573 PF00397 0.490
DOC_WW_Pin1_4 1736 1741 PF00397 0.393
DOC_WW_Pin1_4 1866 1871 PF00397 0.746
DOC_WW_Pin1_4 1931 1936 PF00397 0.649
DOC_WW_Pin1_4 1990 1995 PF00397 0.744
DOC_WW_Pin1_4 235 240 PF00397 0.754
LIG_14-3-3_CanoR_1 1057 1063 PF00244 0.487
LIG_14-3-3_CanoR_1 1248 1257 PF00244 0.428
LIG_14-3-3_CanoR_1 138 143 PF00244 0.630
LIG_14-3-3_CanoR_1 1405 1411 PF00244 0.390
LIG_14-3-3_CanoR_1 154 158 PF00244 0.564
LIG_14-3-3_CanoR_1 1566 1572 PF00244 0.447
LIG_14-3-3_CanoR_1 1725 1734 PF00244 0.463
LIG_14-3-3_CanoR_1 1828 1837 PF00244 0.499
LIG_14-3-3_CanoR_1 1895 1902 PF00244 0.666
LIG_14-3-3_CanoR_1 1952 1960 PF00244 0.733
LIG_14-3-3_CanoR_1 267 272 PF00244 0.728
LIG_14-3-3_CanoR_1 292 297 PF00244 0.535
LIG_14-3-3_CanoR_1 36 43 PF00244 0.752
LIG_14-3-3_CanoR_1 441 447 PF00244 0.729
LIG_14-3-3_CanoR_1 552 560 PF00244 0.557
LIG_14-3-3_CanoR_1 605 610 PF00244 0.533
LIG_14-3-3_CanoR_1 873 879 PF00244 0.515
LIG_14-3-3_CanoR_1 912 920 PF00244 0.577
LIG_14-3-3_CanoR_1 975 981 PF00244 0.520
LIG_Actin_WH2_1 875 891 PF00022 0.544
LIG_Actin_WH2_2 1683 1701 PF00022 0.480
LIG_Actin_WH2_2 1879 1897 PF00022 0.505
LIG_Actin_WH2_2 874 891 PF00022 0.545
LIG_APCC_ABBA_1 1621 1626 PF00400 0.402
LIG_APCC_ABBA_1 699 704 PF00400 0.559
LIG_BIR_III_2 1499 1503 PF00653 0.586
LIG_BIR_III_2 290 294 PF00653 0.498
LIG_BIR_III_4 1064 1068 PF00653 0.675
LIG_BIR_III_4 890 894 PF00653 0.600
LIG_BRCT_BRCA1_1 1740 1744 PF00533 0.402
LIG_BRCT_BRCA1_1 861 865 PF00533 0.599
LIG_Clathr_ClatBox_1 1240 1244 PF01394 0.515
LIG_eIF4E_1 1324 1330 PF01652 0.404
LIG_EVH1_1 1203 1207 PF00568 0.610
LIG_FHA_1 1206 1212 PF00498 0.602
LIG_FHA_1 1249 1255 PF00498 0.408
LIG_FHA_1 137 143 PF00498 0.628
LIG_FHA_1 1377 1383 PF00498 0.493
LIG_FHA_1 1415 1421 PF00498 0.518
LIG_FHA_1 1466 1472 PF00498 0.651
LIG_FHA_1 1647 1653 PF00498 0.425
LIG_FHA_1 1702 1708 PF00498 0.440
LIG_FHA_1 1755 1761 PF00498 0.362
LIG_FHA_1 1874 1880 PF00498 0.549
LIG_FHA_1 236 242 PF00498 0.692
LIG_FHA_1 257 263 PF00498 0.781
LIG_FHA_1 340 346 PF00498 0.452
LIG_FHA_1 389 395 PF00498 0.536
LIG_FHA_1 412 418 PF00498 0.491
LIG_FHA_1 482 488 PF00498 0.532
LIG_FHA_1 510 516 PF00498 0.532
LIG_FHA_1 634 640 PF00498 0.419
LIG_FHA_1 644 650 PF00498 0.474
LIG_FHA_1 709 715 PF00498 0.610
LIG_FHA_1 765 771 PF00498 0.622
LIG_FHA_1 856 862 PF00498 0.510
LIG_FHA_1 975 981 PF00498 0.421
LIG_FHA_2 1059 1065 PF00498 0.589
LIG_FHA_2 1669 1675 PF00498 0.449
LIG_FHA_2 1778 1784 PF00498 0.448
LIG_FHA_2 1978 1984 PF00498 0.756
LIG_FHA_2 2001 2007 PF00498 0.757
LIG_FHA_2 268 274 PF00498 0.765
LIG_FHA_2 293 299 PF00498 0.557
LIG_FHA_2 351 357 PF00498 0.634
LIG_FHA_2 795 801 PF00498 0.608
LIG_FHA_2 955 961 PF00498 0.572
LIG_GBD_Chelix_1 1246 1254 PF00786 0.426
LIG_GBD_Chelix_1 641 649 PF00786 0.484
LIG_GBD_Chelix_1 980 988 PF00786 0.497
LIG_GSK3_LRP6_1 1206 1211 PF00069 0.637
LIG_LIR_Apic_2 1188 1192 PF02991 0.419
LIG_LIR_Apic_2 1200 1206 PF02991 0.501
LIG_LIR_Apic_2 1255 1260 PF02991 0.488
LIG_LIR_Apic_2 31 35 PF02991 0.666
LIG_LIR_Apic_2 44 50 PF02991 0.710
LIG_LIR_Apic_2 704 710 PF02991 0.546
LIG_LIR_Gen_1 1009 1019 PF02991 0.486
LIG_LIR_Gen_1 1161 1170 PF02991 0.545
LIG_LIR_Gen_1 1303 1313 PF02991 0.472
LIG_LIR_Gen_1 1325 1336 PF02991 0.368
LIG_LIR_Gen_1 1379 1387 PF02991 0.504
LIG_LIR_Gen_1 1554 1565 PF02991 0.447
LIG_LIR_Gen_1 1688 1698 PF02991 0.480
LIG_LIR_Gen_1 1908 1918 PF02991 0.588
LIG_LIR_Gen_1 294 304 PF02991 0.544
LIG_LIR_Gen_1 404 413 PF02991 0.504
LIG_LIR_Gen_1 498 507 PF02991 0.382
LIG_LIR_Gen_1 547 558 PF02991 0.439
LIG_LIR_Gen_1 798 808 PF02991 0.575
LIG_LIR_Gen_1 814 822 PF02991 0.513
LIG_LIR_Gen_1 92 103 PF02991 0.636
LIG_LIR_Nem_3 1009 1015 PF02991 0.420
LIG_LIR_Nem_3 1158 1163 PF02991 0.467
LIG_LIR_Nem_3 1303 1308 PF02991 0.451
LIG_LIR_Nem_3 1325 1331 PF02991 0.361
LIG_LIR_Nem_3 1379 1383 PF02991 0.491
LIG_LIR_Nem_3 1554 1560 PF02991 0.447
LIG_LIR_Nem_3 1688 1694 PF02991 0.447
LIG_LIR_Nem_3 1741 1747 PF02991 0.454
LIG_LIR_Nem_3 1908 1914 PF02991 0.597
LIG_LIR_Nem_3 294 299 PF02991 0.539
LIG_LIR_Nem_3 324 328 PF02991 0.564
LIG_LIR_Nem_3 404 409 PF02991 0.463
LIG_LIR_Nem_3 498 504 PF02991 0.376
LIG_LIR_Nem_3 547 553 PF02991 0.436
LIG_LIR_Nem_3 798 804 PF02991 0.558
LIG_LIR_Nem_3 814 819 PF02991 0.475
LIG_LIR_Nem_3 92 98 PF02991 0.605
LIG_MYND_3 463 467 PF01753 0.510
LIG_NRBOX 1249 1255 PF00104 0.436
LIG_NRBOX 143 149 PF00104 0.693
LIG_NRBOX 644 650 PF00104 0.490
LIG_NRBOX 983 989 PF00104 0.433
LIG_PCNA_PIPBox_1 1047 1056 PF02747 0.433
LIG_PCNA_yPIPBox_3 829 840 PF02747 0.608
LIG_PDZ_Class_3 2018 2023 PF00595 0.715
LIG_Pex14_1 610 614 PF04695 0.409
LIG_Pex14_2 1054 1058 PF04695 0.383
LIG_PTB_Apo_2 1299 1306 PF02174 0.387
LIG_PTB_Phospho_1 1299 1305 PF10480 0.384
LIG_REV1ctd_RIR_1 547 553 PF16727 0.509
LIG_SH2_CRK 1012 1016 PF00017 0.489
LIG_SH2_CRK 1305 1309 PF00017 0.485
LIG_SH2_CRK 1691 1695 PF00017 0.447
LIG_SH2_CRK 501 505 PF00017 0.473
LIG_SH2_PTP2 1257 1260 PF00017 0.492
LIG_SH2_SRC 1115 1118 PF00017 0.666
LIG_SH2_STAP1 1324 1328 PF00017 0.413
LIG_SH2_STAP1 519 523 PF00017 0.431
LIG_SH2_STAP1 801 805 PF00017 0.600
LIG_SH2_STAT5 1111 1114 PF00017 0.587
LIG_SH2_STAT5 1257 1260 PF00017 0.481
LIG_SH2_STAT5 1293 1296 PF00017 0.400
LIG_SH2_STAT5 1305 1308 PF00017 0.345
LIG_SH2_STAT5 1324 1327 PF00017 0.384
LIG_SH2_STAT5 1418 1421 PF00017 0.446
LIG_SH2_STAT5 1691 1694 PF00017 0.463
LIG_SH2_STAT5 1750 1753 PF00017 0.395
LIG_SH2_STAT5 1826 1829 PF00017 0.455
LIG_SH2_STAT5 472 475 PF00017 0.483
LIG_SH2_STAT5 522 525 PF00017 0.391
LIG_SH2_STAT5 785 788 PF00017 0.517
LIG_SH2_STAT5 923 926 PF00017 0.520
LIG_SH2_STAT5 986 989 PF00017 0.548
LIG_SH3_1 1343 1349 PF00018 0.595
LIG_SH3_1 1796 1802 PF00018 0.498
LIG_SH3_3 1086 1092 PF00018 0.554
LIG_SH3_3 1201 1207 PF00018 0.551
LIG_SH3_3 1233 1239 PF00018 0.465
LIG_SH3_3 1286 1292 PF00018 0.572
LIG_SH3_3 1343 1349 PF00018 0.595
LIG_SH3_3 1516 1522 PF00018 0.776
LIG_SH3_3 1534 1540 PF00018 0.623
LIG_SH3_3 1606 1612 PF00018 0.447
LIG_SH3_3 1658 1664 PF00018 0.434
LIG_SH3_3 1796 1802 PF00018 0.619
LIG_SH3_3 236 242 PF00018 0.805
LIG_SH3_3 384 390 PF00018 0.522
LIG_SH3_3 58 64 PF00018 0.683
LIG_SH3_3 649 655 PF00018 0.440
LIG_SH3_3 738 744 PF00018 0.664
LIG_SH3_3 891 897 PF00018 0.611
LIG_SUMO_SIM_anti_2 1079 1085 PF11976 0.448
LIG_SUMO_SIM_par_1 1058 1064 PF11976 0.536
LIG_SUMO_SIM_par_1 1239 1244 PF11976 0.432
LIG_SUMO_SIM_par_1 137 143 PF11976 0.380
LIG_SUMO_SIM_par_1 1756 1762 PF11976 0.442
LIG_SUMO_SIM_par_1 575 580 PF11976 0.513
LIG_SUMO_SIM_par_1 687 692 PF11976 0.453
LIG_SUMO_SIM_par_1 868 874 PF11976 0.474
LIG_SUMO_SIM_par_1 944 949 PF11976 0.438
LIG_TRAF2_1 1037 1040 PF00917 0.457
LIG_TRAF2_1 822 825 PF00917 0.698
LIG_TYR_ITIM 1291 1296 PF00017 0.512
LIG_TYR_ITIM 499 504 PF00017 0.468
LIG_TYR_ITSM 1301 1308 PF00017 0.451
LIG_UBA3_1 1024 1031 PF00899 0.414
LIG_UBA3_1 881 889 PF00899 0.498
LIG_UBA3_1 984 991 PF00899 0.548
LIG_WRC_WIRS_1 661 666 PF05994 0.446
MOD_CDK_SPxK_1 1931 1937 PF00069 0.656
MOD_CDK_SPxxK_3 1206 1213 PF00069 0.639
MOD_CK1_1 1122 1128 PF00069 0.642
MOD_CK1_1 1158 1164 PF00069 0.533
MOD_CK1_1 1269 1275 PF00069 0.490
MOD_CK1_1 1314 1320 PF00069 0.508
MOD_CK1_1 1443 1449 PF00069 0.556
MOD_CK1_1 1482 1488 PF00069 0.710
MOD_CK1_1 1492 1498 PF00069 0.762
MOD_CK1_1 1568 1574 PF00069 0.426
MOD_CK1_1 1682 1688 PF00069 0.465
MOD_CK1_1 1689 1695 PF00069 0.475
MOD_CK1_1 169 175 PF00069 0.777
MOD_CK1_1 1701 1707 PF00069 0.313
MOD_CK1_1 1738 1744 PF00069 0.431
MOD_CK1_1 1861 1867 PF00069 0.582
MOD_CK1_1 1873 1879 PF00069 0.523
MOD_CK1_1 1971 1977 PF00069 0.721
MOD_CK1_1 198 204 PF00069 0.524
MOD_CK1_1 1995 2001 PF00069 0.690
MOD_CK1_1 215 221 PF00069 0.772
MOD_CK1_1 240 246 PF00069 0.752
MOD_CK1_1 255 261 PF00069 0.744
MOD_CK1_1 283 289 PF00069 0.660
MOD_CK1_1 307 313 PF00069 0.641
MOD_CK1_1 363 369 PF00069 0.627
MOD_CK1_1 677 683 PF00069 0.565
MOD_CK1_1 708 714 PF00069 0.605
MOD_CK1_1 723 729 PF00069 0.591
MOD_CK1_1 868 874 PF00069 0.482
MOD_CK1_1 963 969 PF00069 0.680
MOD_CK1_1 994 1000 PF00069 0.461
MOD_CK2_1 1034 1040 PF00069 0.601
MOD_CK2_1 1715 1721 PF00069 0.441
MOD_CK2_1 1982 1988 PF00069 0.747
MOD_CK2_1 267 273 PF00069 0.757
MOD_CK2_1 348 354 PF00069 0.524
MOD_CK2_1 442 448 PF00069 0.663
MOD_CK2_1 954 960 PF00069 0.534
MOD_GlcNHglycan 115 118 PF01048 0.765
MOD_GlcNHglycan 119 122 PF01048 0.773
MOD_GlcNHglycan 1273 1276 PF01048 0.421
MOD_GlcNHglycan 1285 1288 PF01048 0.495
MOD_GlcNHglycan 130 133 PF01048 0.448
MOD_GlcNHglycan 1475 1478 PF01048 0.724
MOD_GlcNHglycan 1485 1488 PF01048 0.731
MOD_GlcNHglycan 1549 1552 PF01048 0.494
MOD_GlcNHglycan 1656 1659 PF01048 0.355
MOD_GlcNHglycan 1674 1677 PF01048 0.355
MOD_GlcNHglycan 168 171 PF01048 0.713
MOD_GlcNHglycan 1681 1684 PF01048 0.434
MOD_GlcNHglycan 173 176 PF01048 0.696
MOD_GlcNHglycan 1807 1811 PF01048 0.522
MOD_GlcNHglycan 1838 1841 PF01048 0.614
MOD_GlcNHglycan 1860 1863 PF01048 0.666
MOD_GlcNHglycan 1872 1875 PF01048 0.505
MOD_GlcNHglycan 1924 1928 PF01048 0.632
MOD_GlcNHglycan 1975 1978 PF01048 0.806
MOD_GlcNHglycan 1995 1998 PF01048 0.631
MOD_GlcNHglycan 200 203 PF01048 0.680
MOD_GlcNHglycan 214 217 PF01048 0.681
MOD_GlcNHglycan 219 222 PF01048 0.682
MOD_GlcNHglycan 249 252 PF01048 0.820
MOD_GlcNHglycan 273 276 PF01048 0.761
MOD_GlcNHglycan 306 309 PF01048 0.659
MOD_GlcNHglycan 365 368 PF01048 0.632
MOD_GlcNHglycan 422 425 PF01048 0.509
MOD_GlcNHglycan 430 434 PF01048 0.607
MOD_GlcNHglycan 450 453 PF01048 0.708
MOD_GlcNHglycan 525 528 PF01048 0.497
MOD_GlcNHglycan 556 559 PF01048 0.559
MOD_GlcNHglycan 64 67 PF01048 0.749
MOD_GlcNHglycan 676 679 PF01048 0.557
MOD_GlcNHglycan 681 684 PF01048 0.470
MOD_GlcNHglycan 84 87 PF01048 0.594
MOD_GlcNHglycan 843 846 PF01048 0.672
MOD_GlcNHglycan 962 965 PF01048 0.637
MOD_GlcNHglycan 969 972 PF01048 0.597
MOD_GlcNHglycan 990 994 PF01048 0.564
MOD_GSK3_1 1118 1125 PF00069 0.622
MOD_GSK3_1 113 120 PF00069 0.750
MOD_GSK3_1 1248 1255 PF00069 0.401
MOD_GSK3_1 1271 1278 PF00069 0.411
MOD_GSK3_1 1296 1303 PF00069 0.399
MOD_GSK3_1 1314 1321 PF00069 0.482
MOD_GSK3_1 134 141 PF00069 0.609
MOD_GSK3_1 1429 1436 PF00069 0.539
MOD_GSK3_1 1461 1468 PF00069 0.620
MOD_GSK3_1 1479 1486 PF00069 0.510
MOD_GSK3_1 1488 1495 PF00069 0.712
MOD_GSK3_1 1547 1554 PF00069 0.478
MOD_GSK3_1 164 171 PF00069 0.759
MOD_GSK3_1 1668 1675 PF00069 0.445
MOD_GSK3_1 1682 1689 PF00069 0.482
MOD_GSK3_1 1698 1705 PF00069 0.250
MOD_GSK3_1 1730 1737 PF00069 0.402
MOD_GSK3_1 1797 1804 PF00069 0.650
MOD_GSK3_1 1866 1873 PF00069 0.643
MOD_GSK3_1 1896 1903 PF00069 0.675
MOD_GSK3_1 1967 1974 PF00069 0.728
MOD_GSK3_1 1984 1991 PF00069 0.560
MOD_GSK3_1 1992 1999 PF00069 0.649
MOD_GSK3_1 237 244 PF00069 0.731
MOD_GSK3_1 249 256 PF00069 0.682
MOD_GSK3_1 257 264 PF00069 0.735
MOD_GSK3_1 267 274 PF00069 0.603
MOD_GSK3_1 279 286 PF00069 0.692
MOD_GSK3_1 302 309 PF00069 0.644
MOD_GSK3_1 339 346 PF00069 0.442
MOD_GSK3_1 453 460 PF00069 0.617
MOD_GSK3_1 505 512 PF00069 0.524
MOD_GSK3_1 554 561 PF00069 0.509
MOD_GSK3_1 584 591 PF00069 0.494
MOD_GSK3_1 62 69 PF00069 0.779
MOD_GSK3_1 629 636 PF00069 0.523
MOD_GSK3_1 660 667 PF00069 0.433
MOD_GSK3_1 720 727 PF00069 0.616
MOD_GSK3_1 786 793 PF00069 0.560
MOD_GSK3_1 811 818 PF00069 0.560
MOD_GSK3_1 855 862 PF00069 0.499
MOD_GSK3_1 877 884 PF00069 0.409
MOD_GSK3_1 89 96 PF00069 0.629
MOD_GSK3_1 952 959 PF00069 0.489
MOD_GSK3_1 963 970 PF00069 0.534
MOD_LATS_1 1723 1729 PF00433 0.402
MOD_LATS_1 2011 2017 PF00433 0.692
MOD_LATS_1 386 392 PF00433 0.528
MOD_N-GLC_1 1866 1871 PF02516 0.517
MOD_N-GLC_1 481 486 PF02516 0.548
MOD_NEK2_1 1197 1202 PF00069 0.491
MOD_NEK2_1 1225 1230 PF00069 0.421
MOD_NEK2_1 1296 1301 PF00069 0.386
MOD_NEK2_1 1352 1357 PF00069 0.634
MOD_NEK2_1 1376 1381 PF00069 0.495
MOD_NEK2_1 147 152 PF00069 0.679
MOD_NEK2_1 1473 1478 PF00069 0.741
MOD_NEK2_1 1646 1651 PF00069 0.422
MOD_NEK2_1 1654 1659 PF00069 0.358
MOD_NEK2_1 1665 1670 PF00069 0.447
MOD_NEK2_1 1698 1703 PF00069 0.386
MOD_NEK2_1 1734 1739 PF00069 0.456
MOD_NEK2_1 1827 1832 PF00069 0.434
MOD_NEK2_1 1894 1899 PF00069 0.675
MOD_NEK2_1 1923 1928 PF00069 0.598
MOD_NEK2_1 28 33 PF00069 0.673
MOD_NEK2_1 280 285 PF00069 0.726
MOD_NEK2_1 348 353 PF00069 0.519
MOD_NEK2_1 368 373 PF00069 0.508
MOD_NEK2_1 505 510 PF00069 0.454
MOD_NEK2_1 517 522 PF00069 0.456
MOD_NEK2_1 577 582 PF00069 0.511
MOD_NEK2_1 660 665 PF00069 0.403
MOD_NEK2_1 720 725 PF00069 0.597
MOD_NEK2_1 82 87 PF00069 0.583
MOD_NEK2_1 865 870 PF00069 0.489
MOD_NEK2_1 881 886 PF00069 0.330
MOD_NEK2_1 89 94 PF00069 0.561
MOD_NEK2_1 946 951 PF00069 0.406
MOD_NEK2_2 1507 1512 PF00069 0.716
MOD_OFUCOSY 1645 1650 PF10250 0.480
MOD_PIKK_1 1314 1320 PF00454 0.533
MOD_PIKK_1 1322 1328 PF00454 0.503
MOD_PIKK_1 1392 1398 PF00454 0.567
MOD_PIKK_1 36 42 PF00454 0.717
MOD_PIKK_1 666 672 PF00454 0.462
MOD_PIKK_1 724 730 PF00454 0.616
MOD_PIKK_1 786 792 PF00454 0.595
MOD_PIKK_1 825 831 PF00454 0.674
MOD_PIKK_1 855 861 PF00454 0.537
MOD_PK_1 705 711 PF00069 0.628
MOD_PK_1 991 997 PF00069 0.512
MOD_PKA_1 1461 1467 PF00069 0.637
MOD_PKA_1 164 170 PF00069 0.560
MOD_PKA_1 2013 2019 PF00069 0.794
MOD_PKA_1 247 253 PF00069 0.766
MOD_PKA_1 621 627 PF00069 0.454
MOD_PKA_2 1118 1124 PF00069 0.602
MOD_PKA_2 1488 1494 PF00069 0.756
MOD_PKA_2 153 159 PF00069 0.701
MOD_PKA_2 1565 1571 PF00069 0.447
MOD_PKA_2 164 170 PF00069 0.691
MOD_PKA_2 1698 1704 PF00069 0.438
MOD_PKA_2 1827 1833 PF00069 0.551
MOD_PKA_2 1894 1900 PF00069 0.646
MOD_PKA_2 1966 1972 PF00069 0.771
MOD_PKA_2 2013 2019 PF00069 0.782
MOD_PKA_2 212 218 PF00069 0.727
MOD_PKA_2 247 253 PF00069 0.804
MOD_PKA_2 291 297 PF00069 0.658
MOD_PKA_2 448 454 PF00069 0.697
MOD_PKA_2 621 627 PF00069 0.454
MOD_PKA_2 874 880 PF00069 0.494
MOD_PKA_2 911 917 PF00069 0.535
MOD_PKA_2 939 945 PF00069 0.459
MOD_PKA_2 974 980 PF00069 0.362
MOD_PKB_1 162 170 PF00069 0.563
MOD_PKB_1 1931 1939 PF00069 0.772
MOD_PKB_1 1965 1973 PF00069 0.712
MOD_PKB_1 2012 2020 PF00069 0.625
MOD_Plk_1 1352 1358 PF00069 0.623
MOD_Plk_1 1433 1439 PF00069 0.529
MOD_Plk_1 18 24 PF00069 0.586
MOD_Plk_1 1977 1983 PF00069 0.763
MOD_Plk_1 280 286 PF00069 0.665
MOD_Plk_1 481 487 PF00069 0.543
MOD_Plk_1 5 11 PF00069 0.713
MOD_Plk_1 934 940 PF00069 0.447
MOD_Plk_2-3 1982 1988 PF00069 0.764
MOD_Plk_2-3 273 279 PF00069 0.704
MOD_Plk_2-3 596 602 PF00069 0.520
MOD_Plk_4 1296 1302 PF00069 0.380
MOD_Plk_4 1414 1420 PF00069 0.428
MOD_Plk_4 1440 1446 PF00069 0.477
MOD_Plk_4 153 159 PF00069 0.729
MOD_Plk_4 1551 1557 PF00069 0.334
MOD_Plk_4 1686 1692 PF00069 0.466
MOD_Plk_4 1698 1704 PF00069 0.263
MOD_Plk_4 1738 1744 PF00069 0.470
MOD_Plk_4 1838 1844 PF00069 0.646
MOD_Plk_4 195 201 PF00069 0.795
MOD_Plk_4 321 327 PF00069 0.480
MOD_Plk_4 368 374 PF00069 0.553
MOD_Plk_4 458 464 PF00069 0.615
MOD_Plk_4 577 583 PF00069 0.491
MOD_Plk_4 584 590 PF00069 0.470
MOD_Plk_4 605 611 PF00069 0.482
MOD_Plk_4 780 786 PF00069 0.537
MOD_Plk_4 831 837 PF00069 0.598
MOD_Plk_4 865 871 PF00069 0.449
MOD_Plk_4 874 880 PF00069 0.400
MOD_Plk_4 881 887 PF00069 0.362
MOD_Plk_4 939 945 PF00069 0.437
MOD_Plk_4 946 952 PF00069 0.383
MOD_Plk_4 980 986 PF00069 0.393
MOD_Plk_4 991 997 PF00069 0.404
MOD_ProDKin_1 1015 1021 PF00069 0.577
MOD_ProDKin_1 1034 1040 PF00069 0.297
MOD_ProDKin_1 1120 1126 PF00069 0.719
MOD_ProDKin_1 1206 1212 PF00069 0.570
MOD_ProDKin_1 1536 1542 PF00069 0.733
MOD_ProDKin_1 1568 1574 PF00069 0.490
MOD_ProDKin_1 1736 1742 PF00069 0.393
MOD_ProDKin_1 1866 1872 PF00069 0.746
MOD_ProDKin_1 1931 1937 PF00069 0.656
MOD_ProDKin_1 1990 1996 PF00069 0.746
MOD_ProDKin_1 235 241 PF00069 0.755
MOD_SUMO_for_1 109 112 PF00179 0.551
MOD_SUMO_for_1 1449 1452 PF00179 0.493
TRG_DiLeu_BaEn_1 1079 1084 PF01217 0.464
TRG_DiLeu_BaEn_1 541 546 PF01217 0.551
TRG_DiLeu_BaEn_4 73 79 PF01217 0.620
TRG_DiLeu_BaLyEn_6 1020 1025 PF01217 0.564
TRG_DiLeu_BaLyEn_6 1144 1149 PF01217 0.570
TRG_DiLeu_BaLyEn_6 1236 1241 PF01217 0.522
TRG_DiLeu_BaLyEn_6 314 319 PF01217 0.560
TRG_DiLeu_BaLyEn_6 33 38 PF01217 0.705
TRG_DiLeu_BaLyEn_6 773 778 PF01217 0.545
TRG_DiLeu_BaLyEn_6 942 947 PF01217 0.428
TRG_ENDOCYTIC_2 1012 1015 PF00928 0.471
TRG_ENDOCYTIC_2 1163 1166 PF00928 0.537
TRG_ENDOCYTIC_2 1293 1296 PF00928 0.390
TRG_ENDOCYTIC_2 1298 1301 PF00928 0.368
TRG_ENDOCYTIC_2 1305 1308 PF00928 0.370
TRG_ENDOCYTIC_2 1380 1383 PF00928 0.403
TRG_ENDOCYTIC_2 1691 1694 PF00928 0.447
TRG_ENDOCYTIC_2 1750 1753 PF00928 0.363
TRG_ENDOCYTIC_2 501 504 PF00928 0.472
TRG_ENDOCYTIC_2 531 534 PF00928 0.390
TRG_ENDOCYTIC_2 801 804 PF00928 0.570
TRG_ER_diArg_1 1055 1057 PF00400 0.464
TRG_ER_diArg_1 1135 1137 PF00400 0.705
TRG_ER_diArg_1 162 165 PF00400 0.729
TRG_ER_diArg_1 1827 1829 PF00400 0.440
TRG_ER_diArg_1 1843 1846 PF00400 0.483
TRG_ER_diArg_1 1930 1933 PF00400 0.740
TRG_ER_diArg_1 1962 1965 PF00400 0.754
TRG_ER_diArg_1 2012 2015 PF00400 0.721
TRG_ER_diArg_1 210 213 PF00400 0.654
TRG_ER_diArg_1 246 248 PF00400 0.775
TRG_ER_diArg_1 266 269 PF00400 0.718
TRG_ER_diArg_1 542 545 PF00400 0.572
TRG_ER_diArg_1 620 622 PF00400 0.513
TRG_ER_diArg_1 872 875 PF00400 0.553
TRG_NES_CRM1_1 1075 1090 PF08389 0.474
TRG_NES_CRM1_1 1434 1447 PF08389 0.481
TRG_NLS_MonoExtC_3 1962 1967 PF00514 0.712
TRG_NLS_MonoExtN_4 1960 1967 PF00514 0.748
TRG_Pf-PMV_PEXEL_1 1180 1184 PF00026 0.513
TRG_Pf-PMV_PEXEL_1 1725 1729 PF00026 0.488
TRG_Pf-PMV_PEXEL_1 1829 1834 PF00026 0.419
TRG_Pf-PMV_PEXEL_1 36 40 PF00026 0.668
TRG_Pf-PMV_PEXEL_1 408 412 PF00026 0.464
TRG_Pf-PMV_PEXEL_1 521 525 PF00026 0.335
TRG_Pf-PMV_PEXEL_1 687 692 PF00026 0.423

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXJ0 Leptomonas seymouri 53% 100%
A0A0S4JFK0 Bodo saltans 27% 100%
A0A1X0NNA8 Trypanosomatidae 35% 100%
A0A3Q8I9K3 Leishmania donovani 99% 100%
D0A6U6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AI44 Leishmania braziliensis 79% 100%
E9AP64 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QGB4 Leishmania major 92% 100%
V5B9C6 Trypanosoma cruzi 33% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS