Kinetoplastid kinetochore protein 6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid kinetochore protein 6 - putative

Species:

Leishmania infantum

UniProt:

A4HV52_LEIIN

TriTrypDb:

LINF_120005900

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HV52

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HV52

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	13	15	PF00082	0.456
CLV_PCSK_KEX2_1	4	6	PF00082	0.456
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.456
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.456
CLV_PCSK_SKI1_1	221	225	PF00082	0.534
CLV_PCSK_SKI1_1	39	43	PF00082	0.453
DEG_Nend_UBRbox_4	1	3	PF02207	0.456
DOC_PP2B_LxvP_1	134	137	PF13499	0.663
DOC_PP2B_LxvP_1	54	57	PF13499	0.486
DOC_PP4_FxxP_1	60	63	PF00568	0.479
DOC_USP7_MATH_1	211	215	PF00917	0.550
DOC_USP7_MATH_1	69	73	PF00917	0.485
DOC_WW_Pin1_4	17	22	PF00397	0.588
DOC_WW_Pin1_4	42	47	PF00397	0.453
DOC_WW_Pin1_4	49	54	PF00397	0.450
LIG_14-3-3_CanoR_1	14	22	PF00244	0.474
LIG_14-3-3_CanoR_1	160	164	PF00244	0.617
LIG_14-3-3_CanoR_1	179	188	PF00244	0.459
LIG_14-3-3_CanoR_1	201	206	PF00244	0.599
LIG_deltaCOP1_diTrp_1	144	154	PF00928	0.510
LIG_FHA_1	140	146	PF00498	0.600
LIG_FHA_1	194	200	PF00498	0.466
LIG_FHA_2	146	152	PF00498	0.505
LIG_FHA_2	160	166	PF00498	0.467
LIG_LIR_Gen_1	105	116	PF02991	0.705
LIG_LIR_Nem_3	105	111	PF02991	0.711
LIG_LIR_Nem_3	200	205	PF02991	0.399
LIG_LIR_Nem_3	31	37	PF02991	0.441
LIG_Pex14_2	33	37	PF04695	0.440
LIG_SH2_CRK	225	229	PF00017	0.496
LIG_SH2_GRB2like	108	111	PF00017	0.628
LIG_SH2_PTP2	108	111	PF00017	0.711
LIG_SH2_SRC	108	111	PF00017	0.698
LIG_SH2_STAT3	178	181	PF00017	0.634
LIG_SH2_STAT5	108	111	PF00017	0.711
LIG_SH2_STAT5	81	84	PF00017	0.556
LIG_SH3_3	108	114	PF00018	0.649
LIG_SUMO_SIM_anti_2	263	271	PF11976	0.608
LIG_SUMO_SIM_par_1	87	92	PF11976	0.477
LIG_UBA3_1	245	249	PF00899	0.569
LIG_UBA3_1	269	276	PF00899	0.581
MOD_CK1_1	139	145	PF00069	0.632
MOD_CK1_1	17	23	PF00069	0.471
MOD_CK2_1	143	149	PF00069	0.539
MOD_CK2_1	159	165	PF00069	0.501
MOD_CK2_1	235	241	PF00069	0.472
MOD_Cter_Amidation	11	14	PF01082	0.479
MOD_GlcNHglycan	100	103	PF01048	0.629
MOD_GlcNHglycan	22	25	PF01048	0.620
MOD_GlcNHglycan	71	74	PF01048	0.486
MOD_GSK3_1	139	146	PF00069	0.593
MOD_GSK3_1	268	275	PF00069	0.540
MOD_GSK3_1	42	49	PF00069	0.453
MOD_GSK3_1	8	15	PF00069	0.472
MOD_GSK3_1	98	105	PF00069	0.626
MOD_N-GLC_1	211	216	PF02516	0.546
MOD_NEK2_1	235	240	PF00069	0.468
MOD_NEK2_1	47	52	PF00069	0.463
MOD_NEK2_1	8	13	PF00069	0.468
MOD_PIKK_1	203	209	PF00454	0.608
MOD_PKA_1	13	19	PF00069	0.476
MOD_PKA_2	13	19	PF00069	0.644
MOD_PKA_2	159	165	PF00069	0.540
MOD_PKA_2	63	69	PF00069	0.479
MOD_Plk_1	143	149	PF00069	0.567
MOD_Plk_1	184	190	PF00069	0.472
MOD_Plk_1	235	241	PF00069	0.472
MOD_Plk_4	268	274	PF00069	0.484
MOD_Plk_4	28	34	PF00069	0.443
MOD_Plk_4	74	80	PF00069	0.471
MOD_ProDKin_1	17	23	PF00069	0.588
MOD_ProDKin_1	42	48	PF00069	0.452
MOD_ProDKin_1	49	55	PF00069	0.452
TRG_DiLeu_BaEn_1	166	171	PF01217	0.470
TRG_DiLeu_BaEn_1	92	97	PF01217	0.690
TRG_ENDOCYTIC_2	108	111	PF00928	0.711
TRG_ENDOCYTIC_2	225	228	PF00928	0.495
TRG_ER_diArg_1	218	221	PF00400	0.533
TRG_NES_CRM1_1	222	236	PF08389	0.486

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBR7	Leptomonas seymouri	88%	100%
A0A0S4JQ09	Bodo saltans	45%	100%
A0A1X0NM53	Trypanosomatidae	73%	100%
A0A3S7WRW2	Leishmania donovani	100%	100%
A0A422N6G0	Trypanosoma rangeli	70%	100%
A4H6S4	Leishmania braziliensis	92%	100%
C9ZQD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
E9ANT5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
Q4QGT5	Leishmania major	98%	100%