ATP-binding cassette protein subfamily A, member 6

Quick info Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-binding cassette subfamily A - member 1 - putative

Species:

Leishmania infantum

UniProt:

A4HV35_LEIIN

TriTrypDb:

LINF_110018700

Length:

1895

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 44
NetGPI	no	yes: 0, no: 44

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	45
GO:0110165	cellular anatomical entity	1	45
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7

Phosphorylation

Amastigote: 165

Expansion

Sequence features

A4HV35

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HV35

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	7
GO:0006869	lipid transport	5	7
GO:0051179	localization	1	7
GO:0051234	establishment of localization	2	7
GO:0071702	organic substance transport	4	7

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	45
GO:0005215	transporter activity	1	45
GO:0005488	binding	1	45
GO:0005524	ATP binding	5	45
GO:0015399	primary active transmembrane transporter activity	4	45
GO:0017076	purine nucleotide binding	4	45
GO:0022804	active transmembrane transporter activity	3	45
GO:0022857	transmembrane transporter activity	2	45
GO:0030554	adenyl nucleotide binding	5	45
GO:0032553	ribonucleotide binding	3	45
GO:0032555	purine ribonucleotide binding	4	45
GO:0032559	adenyl ribonucleotide binding	5	45
GO:0035639	purine ribonucleoside triphosphate binding	4	45
GO:0036094	small molecule binding	2	45
GO:0042626	ATPase-coupled transmembrane transporter activity	2	45
GO:0043167	ion binding	2	45
GO:0043168	anion binding	3	45
GO:0097159	organic cyclic compound binding	2	45
GO:0097367	carbohydrate derivative binding	2	45
GO:0140359	ABC-type transporter activity	3	45
GO:0140657	ATP-dependent activity	1	45
GO:1901265	nucleoside phosphate binding	3	45
GO:1901363	heterocyclic compound binding	2	45
GO:0003824	catalytic activity	1	1
GO:0016787	hydrolase activity	2	1
GO:0005319	lipid transporter activity	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1104	1108	PF00656	0.298
CLV_C14_Caspase3-7	1109	1113	PF00656	0.286
CLV_C14_Caspase3-7	1251	1255	PF00656	0.254
CLV_C14_Caspase3-7	1765	1769	PF00656	0.776
CLV_NRD_NRD_1	1329	1331	PF00675	0.369
CLV_NRD_NRD_1	1379	1381	PF00675	0.304
CLV_NRD_NRD_1	140	142	PF00675	0.477
CLV_NRD_NRD_1	1511	1513	PF00675	0.260
CLV_NRD_NRD_1	1541	1543	PF00675	0.349
CLV_NRD_NRD_1	1657	1659	PF00675	0.478
CLV_NRD_NRD_1	1715	1717	PF00675	0.556
CLV_NRD_NRD_1	1736	1738	PF00675	0.527
CLV_NRD_NRD_1	1785	1787	PF00675	0.550
CLV_NRD_NRD_1	1798	1800	PF00675	0.525
CLV_NRD_NRD_1	528	530	PF00675	0.478
CLV_NRD_NRD_1	581	583	PF00675	0.310
CLV_NRD_NRD_1	651	653	PF00675	0.218
CLV_NRD_NRD_1	692	694	PF00675	0.335
CLV_NRD_NRD_1	716	718	PF00675	0.276
CLV_NRD_NRD_1	746	748	PF00675	0.336
CLV_NRD_NRD_1	754	756	PF00675	0.329
CLV_NRD_NRD_1	944	946	PF00675	0.343
CLV_PCSK_KEX2_1	1328	1330	PF00082	0.379
CLV_PCSK_KEX2_1	1511	1513	PF00082	0.259
CLV_PCSK_KEX2_1	1541	1543	PF00082	0.349
CLV_PCSK_KEX2_1	1633	1635	PF00082	0.389
CLV_PCSK_KEX2_1	1656	1658	PF00082	0.458
CLV_PCSK_KEX2_1	1714	1716	PF00082	0.586
CLV_PCSK_KEX2_1	1735	1737	PF00082	0.520
CLV_PCSK_KEX2_1	1785	1787	PF00082	0.403
CLV_PCSK_KEX2_1	1800	1802	PF00082	0.516
CLV_PCSK_KEX2_1	590	592	PF00082	0.417
CLV_PCSK_KEX2_1	651	653	PF00082	0.245
CLV_PCSK_KEX2_1	692	694	PF00082	0.334
CLV_PCSK_KEX2_1	716	718	PF00082	0.270
CLV_PCSK_KEX2_1	746	748	PF00082	0.336
CLV_PCSK_KEX2_1	754	756	PF00082	0.329
CLV_PCSK_KEX2_1	936	938	PF00082	0.312
CLV_PCSK_PC1ET2_1	1633	1635	PF00082	0.395
CLV_PCSK_PC1ET2_1	1656	1658	PF00082	0.458
CLV_PCSK_PC1ET2_1	1714	1716	PF00082	0.555
CLV_PCSK_PC1ET2_1	1800	1802	PF00082	0.389
CLV_PCSK_PC1ET2_1	590	592	PF00082	0.417
CLV_PCSK_PC1ET2_1	716	718	PF00082	0.262
CLV_PCSK_PC1ET2_1	936	938	PF00082	0.311
CLV_PCSK_SKI1_1	1031	1035	PF00082	0.486
CLV_PCSK_SKI1_1	1092	1096	PF00082	0.493
CLV_PCSK_SKI1_1	145	149	PF00082	0.609
CLV_PCSK_SKI1_1	1475	1479	PF00082	0.258
CLV_PCSK_SKI1_1	1525	1529	PF00082	0.240
CLV_PCSK_SKI1_1	1634	1638	PF00082	0.372
CLV_PCSK_SKI1_1	1691	1695	PF00082	0.578
CLV_PCSK_SKI1_1	1722	1726	PF00082	0.388
CLV_PCSK_SKI1_1	315	319	PF00082	0.467
CLV_PCSK_SKI1_1	343	347	PF00082	0.320
CLV_PCSK_SKI1_1	44	48	PF00082	0.562
CLV_PCSK_SKI1_1	680	684	PF00082	0.218
CLV_PCSK_SKI1_1	692	696	PF00082	0.256
CLV_Separin_Metazoa	538	542	PF03568	0.658
CLV_Separin_Metazoa	751	755	PF03568	0.590
DEG_APCC_DBOX_1	643	651	PF00400	0.453
DEG_APCC_DBOX_1	691	699	PF00400	0.548
DEG_Nend_UBRbox_2	1	3	PF02207	0.456
DEG_SCF_FBW7_1	493	498	PF00400	0.162
DEG_SPOP_SBC_1	302	306	PF00917	0.183
DOC_CYCLIN_RxL_1	1387	1396	PF00134	0.389
DOC_CYCLIN_RxL_1	310	322	PF00134	0.312
DOC_CYCLIN_RxL_1	96	106	PF00134	0.352
DOC_CYCLIN_yCln2_LP_2	1263	1269	PF00134	0.194
DOC_CYCLIN_yCln2_LP_2	19	25	PF00134	0.346
DOC_MAPK_gen_1	1366	1373	PF00069	0.587
DOC_MAPK_gen_1	1511	1520	PF00069	0.461
DOC_MAPK_gen_1	1799	1806	PF00069	0.591
DOC_MAPK_gen_1	315	325	PF00069	0.381
DOC_MAPK_gen_1	348	358	PF00069	0.488
DOC_MAPK_gen_1	529	535	PF00069	0.685
DOC_MAPK_gen_1	587	595	PF00069	0.594
DOC_MAPK_gen_1	692	700	PF00069	0.508
DOC_MAPK_gen_1	716	725	PF00069	0.473
DOC_MAPK_MEF2A_6	1194	1203	PF00069	0.221
DOC_MAPK_MEF2A_6	1511	1520	PF00069	0.461
DOC_MAPK_MEF2A_6	319	327	PF00069	0.329
DOC_MAPK_MEF2A_6	603	611	PF00069	0.486
DOC_MAPK_MEF2A_6	716	725	PF00069	0.467
DOC_MAPK_RevD_3	732	747	PF00069	0.528
DOC_PP1_RVXF_1	1259	1266	PF00149	0.301
DOC_PP1_RVXF_1	1389	1396	PF00149	0.470
DOC_PP1_RVXF_1	1523	1529	PF00149	0.477
DOC_PP1_RVXF_1	1631	1638	PF00149	0.529
DOC_PP1_RVXF_1	388	394	PF00149	0.165
DOC_PP1_RVXF_1	97	104	PF00149	0.345
DOC_PP2B_LxvP_1	1033	1036	PF13499	0.316
DOC_PP2B_LxvP_1	1291	1294	PF13499	0.183
DOC_PP2B_LxvP_1	19	22	PF13499	0.293
DOC_PP2B_LxvP_1	441	444	PF13499	0.314
DOC_PP2B_LxvP_1	55	58	PF13499	0.280
DOC_PP2B_PxIxI_1	1198	1204	PF00149	0.181
DOC_PP4_FxxP_1	1637	1640	PF00568	0.545
DOC_PP4_FxxP_1	333	336	PF00568	0.343
DOC_PP4_FxxP_1	543	546	PF00568	0.501
DOC_USP7_MATH_1	1227	1231	PF00917	0.513
DOC_USP7_MATH_1	180	184	PF00917	0.266
DOC_USP7_MATH_1	1882	1886	PF00917	0.591
DOC_USP7_MATH_1	232	236	PF00917	0.358
DOC_USP7_MATH_1	447	451	PF00917	0.342
DOC_USP7_MATH_1	495	499	PF00917	0.348
DOC_USP7_MATH_1	51	55	PF00917	0.385
DOC_USP7_MATH_1	830	834	PF00917	0.671
DOC_USP7_UBL2_3	1095	1099	PF12436	0.304
DOC_USP7_UBL2_3	1588	1592	PF12436	0.568
DOC_USP7_UBL2_3	315	319	PF12436	0.175
DOC_WW_Pin1_4	1699	1704	PF00397	0.737
DOC_WW_Pin1_4	1817	1822	PF00397	0.587
DOC_WW_Pin1_4	217	222	PF00397	0.229
DOC_WW_Pin1_4	460	465	PF00397	0.254
DOC_WW_Pin1_4	491	496	PF00397	0.339
DOC_WW_Pin1_4	726	731	PF00397	0.437
LIG_14-3-3_CanoR_1	1037	1042	PF00244	0.230
LIG_14-3-3_CanoR_1	1511	1517	PF00244	0.461
LIG_14-3-3_CanoR_1	1542	1551	PF00244	0.499
LIG_14-3-3_CanoR_1	1658	1666	PF00244	0.660
LIG_14-3-3_CanoR_1	181	185	PF00244	0.328
LIG_14-3-3_CanoR_1	428	433	PF00244	0.487
LIG_14-3-3_CanoR_1	717	722	PF00244	0.454
LIG_14-3-3_CanoR_1	746	751	PF00244	0.549
LIG_14-3-3_CanoR_1	754	763	PF00244	0.527
LIG_14-3-3_CanoR_1	821	827	PF00244	0.534
LIG_14-3-3_CanoR_1	869	874	PF00244	0.624
LIG_14-3-3_CanoR_1	925	934	PF00244	0.515
LIG_Actin_WH2_2	1366	1382	PF00022	0.488
LIG_Actin_WH2_2	1567	1585	PF00022	0.526
LIG_APCC_ABBA_1	514	519	PF00400	0.307
LIG_BRCT_BRCA1_1	1218	1222	PF00533	0.335
LIG_BRCT_BRCA1_1	1645	1649	PF00533	0.529
LIG_BRCT_BRCA1_1	234	238	PF00533	0.170
LIG_BRCT_BRCA1_1	396	400	PF00533	0.225
LIG_BRCT_BRCA1_1	791	795	PF00533	0.532
LIG_BRCT_BRCA1_1	979	983	PF00533	0.311
LIG_BRCT_BRCA1_2	791	797	PF00533	0.528
LIG_CaM_IQ_9	935	950	PF13499	0.510
LIG_Clathr_ClatBox_1	1461	1465	PF01394	0.488
LIG_Clathr_ClatBox_1	731	735	PF01394	0.462
LIG_EH1_1	24	32	PF00400	0.368
LIG_eIF4E_1	1068	1074	PF01652	0.316
LIG_eIF4E_1	1734	1740	PF01652	0.533
LIG_eIF4E_1	294	300	PF01652	0.324
LIG_eIF4E_1	312	318	PF01652	0.349
LIG_FHA_1	1078	1084	PF00498	0.329
LIG_FHA_1	1085	1091	PF00498	0.309
LIG_FHA_1	1161	1167	PF00498	0.343
LIG_FHA_1	1173	1179	PF00498	0.328
LIG_FHA_1	1230	1236	PF00498	0.326
LIG_FHA_1	1254	1260	PF00498	0.287
LIG_FHA_1	1319	1325	PF00498	0.379
LIG_FHA_1	1412	1418	PF00498	0.475
LIG_FHA_1	1456	1462	PF00498	0.527
LIG_FHA_1	146	152	PF00498	0.404
LIG_FHA_1	1559	1565	PF00498	0.519
LIG_FHA_1	1571	1577	PF00498	0.510
LIG_FHA_1	1692	1698	PF00498	0.734
LIG_FHA_1	1721	1727	PF00498	0.587
LIG_FHA_1	251	257	PF00498	0.266
LIG_FHA_1	318	324	PF00498	0.308
LIG_FHA_1	339	345	PF00498	0.357
LIG_FHA_1	371	377	PF00498	0.325
LIG_FHA_1	403	409	PF00498	0.313
LIG_FHA_1	411	417	PF00498	0.298
LIG_FHA_1	470	476	PF00498	0.225
LIG_FHA_1	617	623	PF00498	0.498
LIG_FHA_1	624	630	PF00498	0.472
LIG_FHA_1	747	753	PF00498	0.530
LIG_FHA_1	759	765	PF00498	0.487
LIG_FHA_1	999	1005	PF00498	0.321
LIG_FHA_2	1102	1108	PF00498	0.290
LIG_FHA_2	13	19	PF00498	0.495
LIG_FHA_2	1438	1444	PF00498	0.399
LIG_FHA_2	1461	1467	PF00498	0.472
LIG_FHA_2	1667	1673	PF00498	0.565
LIG_FHA_2	207	213	PF00498	0.295
LIG_FHA_2	234	240	PF00498	0.232
LIG_FHA_2	293	299	PF00498	0.347
LIG_FHA_2	666	672	PF00498	0.468
LIG_FHA_2	874	880	PF00498	0.533
LIG_FHA_2	895	901	PF00498	0.618
LIG_GBD_Chelix_1	113	121	PF00786	0.456
LIG_GBD_Chelix_1	1201	1209	PF00786	0.368
LIG_GBD_Chelix_1	1238	1246	PF00786	0.379
LIG_IRF3_LxIS_1	1674	1679	PF10401	0.519
LIG_LIR_Apic_2	1844	1850	PF02991	0.788
LIG_LIR_Apic_2	332	336	PF02991	0.375
LIG_LIR_Apic_2	839	845	PF02991	0.529
LIG_LIR_Gen_1	1672	1680	PF02991	0.562
LIG_LIR_Gen_1	206	213	PF02991	0.329
LIG_LIR_Gen_1	235	246	PF02991	0.294
LIG_LIR_Gen_1	275	285	PF02991	0.282
LIG_LIR_Gen_1	397	408	PF02991	0.294
LIG_LIR_Gen_1	498	509	PF02991	0.324
LIG_LIR_Gen_1	561	572	PF02991	0.666
LIG_LIR_Gen_1	749	756	PF02991	0.526
LIG_LIR_Gen_1	879	890	PF02991	0.546
LIG_LIR_LC3C_4	820	824	PF02991	0.451
LIG_LIR_Nem_3	1057	1063	PF02991	0.327
LIG_LIR_Nem_3	1156	1160	PF02991	0.551
LIG_LIR_Nem_3	1313	1317	PF02991	0.272
LIG_LIR_Nem_3	1400	1406	PF02991	0.468
LIG_LIR_Nem_3	1646	1652	PF02991	0.537
LIG_LIR_Nem_3	165	170	PF02991	0.331
LIG_LIR_Nem_3	1672	1678	PF02991	0.557
LIG_LIR_Nem_3	195	201	PF02991	0.282
LIG_LIR_Nem_3	206	210	PF02991	0.278
LIG_LIR_Nem_3	235	241	PF02991	0.326
LIG_LIR_Nem_3	275	280	PF02991	0.275
LIG_LIR_Nem_3	282	288	PF02991	0.289
LIG_LIR_Nem_3	306	312	PF02991	0.296
LIG_LIR_Nem_3	397	403	PF02991	0.275
LIG_LIR_Nem_3	498	504	PF02991	0.333
LIG_LIR_Nem_3	507	511	PF02991	0.321
LIG_LIR_Nem_3	561	567	PF02991	0.652
LIG_LIR_Nem_3	674	679	PF02991	0.504
LIG_LIR_Nem_3	749	753	PF02991	0.534
LIG_LIR_Nem_3	850	855	PF02991	0.601
LIG_LIR_Nem_3	879	885	PF02991	0.528
LIG_PCNA_yPIPBox_3	1366	1377	PF02747	0.595
LIG_PCNA_yPIPBox_3	1668	1677	PF02747	0.530
LIG_Pex14_1	1161	1165	PF04695	0.317
LIG_Pex14_1	1305	1309	PF04695	0.370
LIG_Pex14_1	370	374	PF04695	0.366
LIG_Pex14_2	1056	1060	PF04695	0.198
LIG_Pex14_2	1157	1161	PF04695	0.478
LIG_Pex14_2	1237	1241	PF04695	0.337
LIG_PTB_Apo_2	1161	1168	PF02174	0.342
LIG_PTB_Apo_2	1389	1396	PF02174	0.444
LIG_PTB_Apo_2	161	168	PF02174	0.331
LIG_PTB_Phospho_1	161	167	PF10480	0.175
LIG_Rb_LxCxE_1	666	674	PF01857	0.399
LIG_REV1ctd_RIR_1	421	430	PF16727	0.478
LIG_SH2_CRK	1038	1042	PF00017	0.291
LIG_SH2_CRK	1079	1083	PF00017	0.241
LIG_SH2_CRK	1436	1440	PF00017	0.544
LIG_SH2_CRK	1471	1475	PF00017	0.460
LIG_SH2_CRK	167	171	PF00017	0.245
LIG_SH2_CRK	1706	1710	PF00017	0.602
LIG_SH2_CRK	1847	1851	PF00017	0.769
LIG_SH2_CRK	49	53	PF00017	0.321
LIG_SH2_CRK	501	505	PF00017	0.323
LIG_SH2_CRK	676	680	PF00017	0.510
LIG_SH2_CRK	804	808	PF00017	0.531
LIG_SH2_CRK	842	846	PF00017	0.536
LIG_SH2_GRB2like	116	119	PF00017	0.352
LIG_SH2_GRB2like	1822	1825	PF00017	0.610
LIG_SH2_GRB2like	191	194	PF00017	0.277
LIG_SH2_GRB2like	637	640	PF00017	0.450
LIG_SH2_NCK_1	1436	1440	PF00017	0.501
LIG_SH2_NCK_1	49	53	PF00017	0.382
LIG_SH2_SRC	116	119	PF00017	0.340
LIG_SH2_SRC	1436	1439	PF00017	0.534
LIG_SH2_SRC	1862	1865	PF00017	0.761
LIG_SH2_SRC	201	204	PF00017	0.293
LIG_SH2_SRC	517	520	PF00017	0.416
LIG_SH2_SRC	637	640	PF00017	0.490
LIG_SH2_STAP1	1038	1042	PF00017	0.259
LIG_SH2_STAP1	1079	1083	PF00017	0.318
LIG_SH2_STAP1	1338	1342	PF00017	0.524
LIG_SH2_STAP1	1822	1826	PF00017	0.761
LIG_SH2_STAP1	303	307	PF00017	0.382
LIG_SH2_STAP1	374	378	PF00017	0.303
LIG_SH2_STAP1	501	505	PF00017	0.382
LIG_SH2_STAP1	574	578	PF00017	0.546
LIG_SH2_STAP1	748	752	PF00017	0.599
LIG_SH2_STAP1	871	875	PF00017	0.582
LIG_SH2_STAT3	1081	1084	PF00017	0.316
LIG_SH2_STAT3	1451	1454	PF00017	0.483
LIG_SH2_STAT3	1849	1852	PF00017	0.574
LIG_SH2_STAT3	374	377	PF00017	0.305
LIG_SH2_STAT3	656	659	PF00017	0.561
LIG_SH2_STAT5	1010	1013	PF00017	0.223
LIG_SH2_STAT5	1038	1041	PF00017	0.293
LIG_SH2_STAT5	1079	1082	PF00017	0.278
LIG_SH2_STAT5	1158	1161	PF00017	0.528
LIG_SH2_STAT5	116	119	PF00017	0.318
LIG_SH2_STAT5	1172	1175	PF00017	0.295
LIG_SH2_STAT5	1191	1194	PF00017	0.178
LIG_SH2_STAT5	1216	1219	PF00017	0.246
LIG_SH2_STAT5	1273	1276	PF00017	0.269
LIG_SH2_STAT5	1432	1435	PF00017	0.515
LIG_SH2_STAT5	1451	1454	PF00017	0.426
LIG_SH2_STAT5	1664	1667	PF00017	0.552
LIG_SH2_STAT5	177	180	PF00017	0.311
LIG_SH2_STAT5	1886	1889	PF00017	0.795
LIG_SH2_STAT5	191	194	PF00017	0.265
LIG_SH2_STAT5	198	201	PF00017	0.257
LIG_SH2_STAT5	272	275	PF00017	0.260
LIG_SH2_STAT5	288	291	PF00017	0.286
LIG_SH2_STAT5	294	297	PF00017	0.300
LIG_SH2_STAT5	378	381	PF00017	0.338
LIG_SH2_STAT5	407	410	PF00017	0.320
LIG_SH2_STAT5	438	441	PF00017	0.315
LIG_SH2_STAT5	49	52	PF00017	0.392
LIG_SH2_STAT5	512	515	PF00017	0.301
LIG_SH2_STAT5	517	520	PF00017	0.375
LIG_SH2_STAT5	637	640	PF00017	0.490
LIG_SH2_STAT5	656	659	PF00017	0.394
LIG_SH2_STAT5	748	751	PF00017	0.618
LIG_SH2_STAT5	997	1000	PF00017	0.314
LIG_SH3_3	122	128	PF00018	0.350
LIG_SH3_3	1291	1297	PF00018	0.282
LIG_SH3_3	1300	1306	PF00018	0.290
LIG_SH3_3	949	955	PF00018	0.329
LIG_SUMO_SIM_anti_2	1175	1180	PF11976	0.216
LIG_SUMO_SIM_anti_2	1458	1463	PF11976	0.527
LIG_SUMO_SIM_anti_2	15	21	PF11976	0.305
LIG_SUMO_SIM_anti_2	606	611	PF11976	0.474
LIG_SUMO_SIM_anti_2	697	702	PF11976	0.462
LIG_SUMO_SIM_par_1	1248	1256	PF11976	0.352
LIG_SUMO_SIM_par_1	1456	1463	PF11976	0.488
LIG_SUMO_SIM_par_1	1721	1728	PF11976	0.592
LIG_SUMO_SIM_par_1	327	332	PF11976	0.258
LIG_SUMO_SIM_par_1	439	445	PF11976	0.318
LIG_SUMO_SIM_par_1	472	478	PF11976	0.325
LIG_SUMO_SIM_par_1	760	766	PF11976	0.493
LIG_SUMO_SIM_par_1	806	811	PF11976	0.553
LIG_SUMO_SIM_par_1	963	969	PF11976	0.292
LIG_TRAF2_1	1463	1466	PF00917	0.468
LIG_TRAF2_1	209	212	PF00917	0.273
LIG_TRAF2_1	279	282	PF00917	0.183
LIG_TRAF2_1	858	861	PF00917	0.652
LIG_TRAF2_1	877	880	PF00917	0.555
LIG_TRAF2_1	898	901	PF00917	0.627
LIG_TRFH_1	1267	1271	PF08558	0.291
LIG_TYR_ITIM	376	381	PF00017	0.419
LIG_TYR_ITIM	436	441	PF00017	0.315
LIG_TYR_ITIM	47	52	PF00017	0.342
LIG_TYR_ITIM	509	514	PF00017	0.269
LIG_TYR_ITIM	802	807	PF00017	0.553
LIG_TYR_ITSM	163	170	PF00017	0.221
LIG_UBA3_1	135	142	PF00899	0.219
LIG_UBA3_1	855	864	PF00899	0.543
LIG_WRC_WIRS_1	1083	1088	PF05994	0.202
LIG_WRC_WIRS_1	1217	1222	PF05994	0.291
LIG_WRC_WIRS_1	330	335	PF05994	0.277
LIG_WRC_WIRS_1	443	448	PF05994	0.239
LIG_WRC_WIRS_1	967	972	PF05994	0.260
MOD_CK1_1	1009	1015	PF00069	0.314
MOD_CK1_1	1153	1159	PF00069	0.563
MOD_CK1_1	1211	1217	PF00069	0.436
MOD_CK1_1	1667	1673	PF00069	0.561
MOD_CK1_1	1699	1705	PF00069	0.756
MOD_CK1_1	338	344	PF00069	0.377
MOD_CK1_1	362	368	PF00069	0.437
MOD_CK1_1	442	448	PF00069	0.362
MOD_CK1_1	449	455	PF00069	0.300
MOD_CK1_1	460	466	PF00069	0.279
MOD_CK1_1	53	59	PF00069	0.447
MOD_CK1_1	544	550	PF00069	0.517
MOD_CK1_1	790	796	PF00069	0.490
MOD_CK1_1	874	880	PF00069	0.525
MOD_CK1_1	977	983	PF00069	0.286
MOD_CK2_1	1184	1190	PF00069	0.443
MOD_CK2_1	12	18	PF00069	0.488
MOD_CK2_1	1349	1355	PF00069	0.593
MOD_CK2_1	1437	1443	PF00069	0.576
MOD_CK2_1	1460	1466	PF00069	0.464
MOD_CK2_1	1594	1600	PF00069	0.554
MOD_CK2_1	1666	1672	PF00069	0.554
MOD_CK2_1	206	212	PF00069	0.305
MOD_CK2_1	276	282	PF00069	0.364
MOD_CK2_1	292	298	PF00069	0.173
MOD_CK2_1	308	314	PF00069	0.145
MOD_CK2_1	665	671	PF00069	0.445
MOD_CK2_1	851	857	PF00069	0.492
MOD_CK2_1	87	93	PF00069	0.389
MOD_CK2_1	873	879	PF00069	0.538
MOD_CK2_1	894	900	PF00069	0.620
MOD_CK2_1	966	972	PF00069	0.316
MOD_CK2_1	989	995	PF00069	0.345
MOD_Cter_Amidation	1631	1634	PF01082	0.289
MOD_Cter_Amidation	1688	1691	PF01082	0.462
MOD_Cter_Amidation	1797	1800	PF01082	0.383
MOD_Cter_Amidation	588	591	PF01082	0.429
MOD_GlcNHglycan	1065	1068	PF01048	0.458
MOD_GlcNHglycan	107	110	PF01048	0.423
MOD_GlcNHglycan	1152	1155	PF01048	0.271
MOD_GlcNHglycan	1213	1216	PF01048	0.339
MOD_GlcNHglycan	1224	1228	PF01048	0.288
MOD_GlcNHglycan	1229	1232	PF01048	0.306
MOD_GlcNHglycan	1427	1430	PF01048	0.286
MOD_GlcNHglycan	1502	1505	PF01048	0.273
MOD_GlcNHglycan	1506	1509	PF01048	0.267
MOD_GlcNHglycan	152	155	PF01048	0.651
MOD_GlcNHglycan	1530	1535	PF01048	0.276
MOD_GlcNHglycan	1596	1599	PF01048	0.302
MOD_GlcNHglycan	172	175	PF01048	0.438
MOD_GlcNHglycan	1727	1730	PF01048	0.470
MOD_GlcNHglycan	1796	1799	PF01048	0.535
MOD_GlcNHglycan	1812	1817	PF01048	0.467
MOD_GlcNHglycan	1844	1847	PF01048	0.561
MOD_GlcNHglycan	274	277	PF01048	0.434
MOD_GlcNHglycan	416	419	PF01048	0.356
MOD_GlcNHglycan	451	454	PF01048	0.459
MOD_GlcNHglycan	489	492	PF01048	0.475
MOD_GlcNHglycan	543	546	PF01048	0.450
MOD_GlcNHglycan	711	714	PF01048	0.271
MOD_GlcNHglycan	789	792	PF01048	0.298
MOD_GlcNHglycan	873	876	PF01048	0.347
MOD_GlcNHglycan	89	92	PF01048	0.547
MOD_GlcNHglycan	991	994	PF01048	0.453
MOD_GSK3_1	101	108	PF00069	0.304
MOD_GSK3_1	1020	1027	PF00069	0.252
MOD_GSK3_1	1101	1108	PF00069	0.248
MOD_GSK3_1	1125	1132	PF00069	0.320
MOD_GSK3_1	1223	1230	PF00069	0.479
MOD_GSK3_1	1248	1255	PF00069	0.335
MOD_GSK3_1	1411	1418	PF00069	0.477
MOD_GSK3_1	1500	1507	PF00069	0.487
MOD_GSK3_1	1512	1519	PF00069	0.494
MOD_GSK3_1	1549	1556	PF00069	0.537
MOD_GSK3_1	1662	1669	PF00069	0.595
MOD_GSK3_1	1720	1727	PF00069	0.703
MOD_GSK3_1	180	187	PF00069	0.278
MOD_GSK3_1	1822	1829	PF00069	0.747
MOD_GSK3_1	266	273	PF00069	0.262
MOD_GSK3_1	362	369	PF00069	0.487
MOD_GSK3_1	389	396	PF00069	0.260
MOD_GSK3_1	410	417	PF00069	0.316
MOD_GSK3_1	442	449	PF00069	0.283
MOD_GSK3_1	469	476	PF00069	0.236
MOD_GSK3_1	47	54	PF00069	0.414
MOD_GSK3_1	487	494	PF00069	0.213
MOD_GSK3_1	705	712	PF00069	0.468
MOD_GSK3_1	754	761	PF00069	0.530
MOD_GSK3_1	79	86	PF00069	0.347
MOD_GSK3_1	851	858	PF00069	0.575
MOD_GSK3_1	869	876	PF00069	0.560
MOD_GSK3_1	87	94	PF00069	0.291
MOD_GSK3_1	968	975	PF00069	0.273
MOD_GSK3_1	998	1005	PF00069	0.293
MOD_N-GLC_1	1002	1007	PF02516	0.523
MOD_N-GLC_1	1063	1068	PF02516	0.467
MOD_N-GLC_1	1150	1155	PF02516	0.316
MOD_N-GLC_1	1553	1558	PF02516	0.335
MOD_N-GLC_1	192	197	PF02516	0.454
MOD_N-GLC_1	233	238	PF02516	0.480
MOD_N-GLC_1	47	52	PF02516	0.538
MOD_N-GLC_1	638	643	PF02516	0.322
MOD_N-GLC_1	67	72	PF02516	0.533
MOD_N-GLC_1	87	92	PF02516	0.650
MOD_N-GLC_2	836	838	PF02516	0.367
MOD_NEK2_1	1	6	PF00069	0.565
MOD_NEK2_1	103	108	PF00069	0.346
MOD_NEK2_1	1056	1061	PF00069	0.287
MOD_NEK2_1	1062	1067	PF00069	0.274
MOD_NEK2_1	1105	1110	PF00069	0.225
MOD_NEK2_1	1174	1179	PF00069	0.307
MOD_NEK2_1	1209	1214	PF00069	0.353
MOD_NEK2_1	1248	1253	PF00069	0.344
MOD_NEK2_1	1318	1323	PF00069	0.382
MOD_NEK2_1	1393	1398	PF00069	0.477
MOD_NEK2_1	1405	1410	PF00069	0.463
MOD_NEK2_1	1498	1503	PF00069	0.520
MOD_NEK2_1	156	161	PF00069	0.421
MOD_NEK2_1	1570	1575	PF00069	0.543
MOD_NEK2_1	1599	1604	PF00069	0.546
MOD_NEK2_1	162	167	PF00069	0.299
MOD_NEK2_1	1696	1701	PF00069	0.736
MOD_NEK2_1	1725	1730	PF00069	0.705
MOD_NEK2_1	317	322	PF00069	0.250
MOD_NEK2_1	329	334	PF00069	0.305
MOD_NEK2_1	359	364	PF00069	0.401
MOD_NEK2_1	366	371	PF00069	0.236
MOD_NEK2_1	389	394	PF00069	0.280
MOD_NEK2_1	402	407	PF00069	0.286
MOD_NEK2_1	409	414	PF00069	0.149
MOD_NEK2_1	439	444	PF00069	0.365
MOD_NEK2_1	446	451	PF00069	0.315
MOD_NEK2_1	47	52	PF00069	0.389
MOD_NEK2_1	763	768	PF00069	0.536
MOD_NEK2_1	787	792	PF00069	0.515
MOD_NEK2_1	795	800	PF00069	0.517
MOD_NEK2_1	822	827	PF00069	0.556
MOD_NEK2_1	873	878	PF00069	0.538
MOD_NEK2_1	919	924	PF00069	0.545
MOD_NEK2_1	963	968	PF00069	0.330
MOD_NEK2_1	983	988	PF00069	0.296
MOD_NEK2_1	989	994	PF00069	0.269
MOD_NEK2_1	998	1003	PF00069	0.253
MOD_NEK2_2	665	670	PF00069	0.514
MOD_NEK2_2	830	835	PF00069	0.593
MOD_PIKK_1	145	151	PF00454	0.466
MOD_PIKK_1	1549	1555	PF00454	0.588
MOD_PIKK_1	1664	1670	PF00454	0.553
MOD_PIKK_1	1776	1782	PF00454	0.596
MOD_PIKK_1	335	341	PF00454	0.344
MOD_PIKK_1	925	931	PF00454	0.532
MOD_PK_1	1106	1112	PF00069	0.175
MOD_PK_1	1512	1518	PF00069	0.476
MOD_PK_1	1785	1791	PF00069	0.587
MOD_PK_1	319	325	PF00069	0.175
MOD_PK_1	717	723	PF00069	0.469
MOD_PKA_1	1512	1518	PF00069	0.472
MOD_PKA_1	1691	1697	PF00069	0.627
MOD_PKA_1	1785	1791	PF00069	0.703
MOD_PKA_1	717	723	PF00069	0.473
MOD_PKA_1	746	752	PF00069	0.544
MOD_PKA_1	754	760	PF00069	0.536
MOD_PKA_2	1036	1042	PF00069	0.275
MOD_PKA_2	1105	1111	PF00069	0.236
MOD_PKA_2	1498	1504	PF00069	0.495
MOD_PKA_2	1676	1682	PF00069	0.553
MOD_PKA_2	1785	1791	PF00069	0.788
MOD_PKA_2	180	186	PF00069	0.343
MOD_PKA_2	746	752	PF00069	0.544
MOD_PKA_2	754	760	PF00069	0.536
MOD_PKB_1	923	931	PF00069	0.452
MOD_Plk_1	1	7	PF00069	0.572
MOD_Plk_1	1020	1026	PF00069	0.267
MOD_Plk_1	1056	1062	PF00069	0.279
MOD_Plk_1	1063	1069	PF00069	0.256
MOD_Plk_1	1106	1112	PF00069	0.276
MOD_Plk_1	1455	1461	PF00069	0.528
MOD_Plk_1	1553	1559	PF00069	0.532
MOD_Plk_1	1599	1605	PF00069	0.504
MOD_Plk_1	162	168	PF00069	0.307
MOD_Plk_1	1662	1668	PF00069	0.593
MOD_Plk_1	1720	1726	PF00069	0.708
MOD_Plk_1	47	53	PF00069	0.416
MOD_Plk_1	495	501	PF00069	0.260
MOD_Plk_1	605	611	PF00069	0.490
MOD_Plk_1	67	73	PF00069	0.356
MOD_Plk_1	78	84	PF00069	0.386
MOD_Plk_1	830	836	PF00069	0.570
MOD_Plk_1	91	97	PF00069	0.368
MOD_Plk_2-3	1349	1355	PF00069	0.602
MOD_Plk_2-3	1437	1443	PF00069	0.416
MOD_Plk_2-3	1460	1466	PF00069	0.490
MOD_Plk_2-3	1761	1767	PF00069	0.711
MOD_Plk_4	1006	1012	PF00069	0.258
MOD_Plk_4	1020	1026	PF00069	0.298
MOD_Plk_4	1037	1043	PF00069	0.257
MOD_Plk_4	1056	1062	PF00069	0.256
MOD_Plk_4	1077	1083	PF00069	0.305
MOD_Plk_4	1113	1119	PF00069	0.298
MOD_Plk_4	1153	1159	PF00069	0.526
MOD_Plk_4	1174	1180	PF00069	0.303
MOD_Plk_4	12	18	PF00069	0.471
MOD_Plk_4	1248	1254	PF00069	0.351
MOD_Plk_4	1275	1281	PF00069	0.310
MOD_Plk_4	129	135	PF00069	0.326
MOD_Plk_4	1318	1324	PF00069	0.263
MOD_Plk_4	1516	1522	PF00069	0.529
MOD_Plk_4	1553	1559	PF00069	0.520
MOD_Plk_4	1720	1726	PF00069	0.587
MOD_Plk_4	184	190	PF00069	0.261
MOD_Plk_4	319	325	PF00069	0.278
MOD_Plk_4	329	335	PF00069	0.310
MOD_Plk_4	366	372	PF00069	0.329
MOD_Plk_4	383	389	PF00069	0.321
MOD_Plk_4	402	408	PF00069	0.292
MOD_Plk_4	428	434	PF00069	0.506
MOD_Plk_4	457	463	PF00069	0.247
MOD_Plk_4	495	501	PF00069	0.261
MOD_Plk_4	617	623	PF00069	0.554
MOD_Plk_4	758	764	PF00069	0.530
MOD_Plk_4	790	796	PF00069	0.491
MOD_Plk_4	822	828	PF00069	0.546
MOD_Plk_4	851	857	PF00069	0.530
MOD_Plk_4	963	969	PF00069	0.333
MOD_ProDKin_1	1699	1705	PF00069	0.760
MOD_ProDKin_1	1817	1823	PF00069	0.587
MOD_ProDKin_1	217	223	PF00069	0.229
MOD_ProDKin_1	460	466	PF00069	0.254
MOD_ProDKin_1	491	497	PF00069	0.339
MOD_ProDKin_1	726	732	PF00069	0.437
MOD_SUMO_rev_2	1141	1146	PF00179	0.513
MOD_SUMO_rev_2	1359	1369	PF00179	0.606
MOD_SUMO_rev_2	311	318	PF00179	0.162
TRG_DiLeu_BaEn_1	1721	1726	PF01217	0.574
TRG_DiLeu_BaEn_1	606	611	PF01217	0.488
TRG_DiLeu_BaEn_2	1312	1318	PF01217	0.299
TRG_DiLeu_BaEn_2	1400	1406	PF01217	0.468
TRG_DiLeu_BaEn_4	1465	1471	PF01217	0.496
TRG_DiLeu_BaEn_4	1565	1571	PF01217	0.535
TRG_DiLeu_BaEn_4	1683	1689	PF01217	0.633
TRG_DiLeu_BaLyEn_6	108	113	PF01217	0.217
TRG_DiLeu_BaLyEn_6	432	437	PF01217	0.366
TRG_ENDOCYTIC_2	1038	1041	PF00928	0.274
TRG_ENDOCYTIC_2	1079	1082	PF00928	0.242
TRG_ENDOCYTIC_2	1436	1439	PF00928	0.501
TRG_ENDOCYTIC_2	1471	1474	PF00928	0.470
TRG_ENDOCYTIC_2	167	170	PF00928	0.245
TRG_ENDOCYTIC_2	1706	1709	PF00928	0.600
TRG_ENDOCYTIC_2	378	381	PF00928	0.411
TRG_ENDOCYTIC_2	438	441	PF00928	0.325
TRG_ENDOCYTIC_2	49	52	PF00928	0.384
TRG_ENDOCYTIC_2	501	504	PF00928	0.334
TRG_ENDOCYTIC_2	511	514	PF00928	0.301
TRG_ENDOCYTIC_2	599	602	PF00928	0.484
TRG_ENDOCYTIC_2	61	64	PF00928	0.260
TRG_ENDOCYTIC_2	676	679	PF00928	0.483
TRG_ENDOCYTIC_2	804	807	PF00928	0.517
TRG_ER_diArg_1	1327	1330	PF00400	0.586
TRG_ER_diArg_1	1657	1659	PF00400	0.458
TRG_ER_diArg_1	1734	1737	PF00400	0.646
TRG_ER_diArg_1	350	353	PF00400	0.484
TRG_ER_diArg_1	650	652	PF00400	0.422
TRG_ER_diArg_1	691	693	PF00400	0.535
TRG_ER_diArg_1	746	748	PF00400	0.624
TRG_ER_diArg_1	753	755	PF00400	0.573
TRG_ER_diArg_1	784	787	PF00400	0.434
TRG_ER_diArg_1	923	926	PF00400	0.588
TRG_ER_diLys_1	1891	1895	PF00400	0.556
TRG_NLS_Bipartite_1	1785	1803	PF00514	0.591
TRG_NLS_MonoCore_2	1711	1716	PF00514	0.608
TRG_NLS_MonoExtC_3	1711	1716	PF00514	0.607
TRG_NLS_MonoExtN_4	1712	1717	PF00514	0.796
TRG_Pf-PMV_PEXEL_1	145	149	PF00026	0.655
TRG_Pf-PMV_PEXEL_1	1583	1587	PF00026	0.360
TRG_Pf-PMV_PEXEL_1	3	7	PF00026	0.362
TRG_Pf-PMV_PEXEL_1	693	697	PF00026	0.304

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K1Q8	Rattus norvegicus	30%	100%
A0A0N0P411	Leptomonas seymouri	64%	95%
A0A0N1I1A6	Leptomonas seymouri	27%	100%
A0A0N1IH55	Leptomonas seymouri	47%	100%
A0A0S4IQH9	Bodo saltans	30%	100%
A0A0S4IUV3	Bodo saltans	47%	100%
A0A0S4J5Z1	Bodo saltans	47%	100%
A0A0S4J9S9	Bodo saltans	39%	100%
A0A0S4JDK3	Bodo saltans	37%	100%
A0A0S4JTU9	Bodo saltans	33%	100%
A0A1X0NUW1	Trypanosomatidae	49%	100%
A0A1X0NV41	Trypanosomatidae	47%	100%
A0A1X0NZH7	Trypanosomatidae	28%	99%
A0A3Q8I827	Leishmania donovani	49%	100%
A0A3Q8I970	Leishmania donovani	98%	100%
A0A3Q8IBC5	Leishmania donovani	50%	100%
A0A3Q8IHK0	Leishmania donovani	54%	100%
A0A3R7NVN7	Trypanosoma rangeli	44%	100%
A0A3S7WRQ5	Leishmania donovani	48%	100%
A0A3S7X0K7	Leishmania donovani	48%	100%
A0A3S7X0L1	Leishmania donovani	48%	100%
A0A3S7X267	Leishmania donovani	28%	100%
A0A422NUL9	Trypanosoma rangeli	27%	100%
A4H6P2	Leishmania braziliensis	47%	100%
A4H6P6	Leishmania braziliensis	49%	100%
A4H6P7	Leishmania braziliensis	49%	100%
A4H6P8	Leishmania braziliensis	53%	100%
A4H6Q0	Leishmania braziliensis	75%	100%
A4HFM0	Leishmania braziliensis	49%	100%
A4HH69	Leishmania braziliensis	29%	100%
A4HV29	Leishmania infantum	48%	100%
A4HV31	Leishmania infantum	51%	100%
A4HV32	Leishmania infantum	48%	100%
A4HV33	Leishmania infantum	53%	100%
A4I2P8	Leishmania infantum	49%	100%
A4I4B4	Leishmania infantum	29%	100%
D0A7B9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
E9AD74	Leishmania major	49%	100%
E9AD75	Leishmania major	49%	100%
E9ADR4	Leishmania major	29%	100%
E9AM16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9ANR1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9ANR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9ANR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	54%	100%
E9ANR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
E9AYZ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9PU17	Rattus norvegicus	29%	100%
E9PX95	Mus musculus	28%	100%
Q4QGV3	Leishmania major	92%	100%
Q4QGV5	Leishmania major	53%	100%
Q4QGV7	Leishmania major	47%	100%
Q4QGV8	Leishmania major	49%	100%
Q4QGW0	Leishmania major	47%	100%
Q54BT5	Dictyostelium discoideum	27%	100%
Q555Z5	Dictyostelium discoideum	28%	100%
Q84M24	Arabidopsis thaliana	33%	100%
Q8CF82	Rattus norvegicus	27%	100%
Q8K448	Mus musculus	27%	100%
Q8N139	Homo sapiens	27%	100%
Q8R420	Mus musculus	29%	100%
Q8T6J1	Dictyostelium discoideum	27%	100%
Q8T6J2	Dictyostelium discoideum	28%	100%
Q8T6J5	Dictyostelium discoideum	28%	100%
Q8WWZ7	Homo sapiens	28%	100%
Q99758	Homo sapiens	32%	100%
V5B4J7	Trypanosoma cruzi	47%	100%
V5BWI9	Trypanosoma cruzi	49%	100%
V5DLF4	Trypanosoma cruzi	26%	100%