ATP-binding cassette protein subfamily A, member 2

Quick info Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-binding cassette protein subfamily A, member 2, putative

Species:

Leishmania infantum

UniProt:

A4HV29_LEIIN

TriTrypDb:

LINF_110018150

Length:

1776

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 47
NetGPI	no	yes: 0, no: 47

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	48
GO:0110165	cellular anatomical entity	1	48
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7

Phosphorylation

Amastigote: 1767, 1768

Expansion

Sequence features

A4HV29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HV29

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	7
GO:0006869	lipid transport	5	7
GO:0051179	localization	1	7
GO:0051234	establishment of localization	2	7
GO:0071702	organic substance transport	4	7

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	48
GO:0005215	transporter activity	1	48
GO:0005488	binding	1	48
GO:0005524	ATP binding	5	48
GO:0015399	primary active transmembrane transporter activity	4	48
GO:0017076	purine nucleotide binding	4	48
GO:0022804	active transmembrane transporter activity	3	48
GO:0022857	transmembrane transporter activity	2	48
GO:0030554	adenyl nucleotide binding	5	48
GO:0032553	ribonucleotide binding	3	48
GO:0032555	purine ribonucleotide binding	4	48
GO:0032559	adenyl ribonucleotide binding	5	48
GO:0035639	purine ribonucleoside triphosphate binding	4	48
GO:0036094	small molecule binding	2	48
GO:0042626	ATPase-coupled transmembrane transporter activity	2	48
GO:0043167	ion binding	2	48
GO:0043168	anion binding	3	48
GO:0097159	organic cyclic compound binding	2	48
GO:0097367	carbohydrate derivative binding	2	48
GO:0140359	ABC-type transporter activity	3	48
GO:0140657	ATP-dependent activity	1	48
GO:1901265	nucleoside phosphate binding	3	48
GO:1901363	heterocyclic compound binding	2	48
GO:0003824	catalytic activity	1	1
GO:0016787	hydrolase activity	2	1
GO:0005319	lipid transporter activity	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1179	1183	PF00656	0.275
CLV_C14_Caspase3-7	966	970	PF00656	0.563
CLV_NRD_NRD_1	1399	1401	PF00675	0.366
CLV_NRD_NRD_1	1428	1430	PF00675	0.358
CLV_NRD_NRD_1	1549	1551	PF00675	0.273
CLV_NRD_NRD_1	1579	1581	PF00675	0.255
CLV_NRD_NRD_1	1609	1611	PF00675	0.330
CLV_NRD_NRD_1	1703	1705	PF00675	0.403
CLV_NRD_NRD_1	222	224	PF00675	0.446
CLV_NRD_NRD_1	615	617	PF00675	0.312
CLV_NRD_NRD_1	750	752	PF00675	0.274
CLV_NRD_NRD_1	780	782	PF00675	0.333
CLV_NRD_NRD_1	8	10	PF00675	0.475
CLV_NRD_NRD_1	930	932	PF00675	0.489
CLV_PCSK_FUR_1	1701	1705	PF00082	0.442
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.283
CLV_PCSK_KEX2_1	1399	1401	PF00082	0.374
CLV_PCSK_KEX2_1	1428	1430	PF00082	0.355
CLV_PCSK_KEX2_1	1551	1553	PF00082	0.297
CLV_PCSK_KEX2_1	1579	1581	PF00082	0.258
CLV_PCSK_KEX2_1	1609	1611	PF00082	0.330
CLV_PCSK_KEX2_1	1703	1705	PF00082	0.405
CLV_PCSK_KEX2_1	32	34	PF00082	0.307
CLV_PCSK_KEX2_1	376	378	PF00082	0.303
CLV_PCSK_KEX2_1	624	626	PF00082	0.412
CLV_PCSK_KEX2_1	737	739	PF00082	0.269
CLV_PCSK_KEX2_1	750	752	PF00082	0.274
CLV_PCSK_KEX2_1	780	782	PF00082	0.333
CLV_PCSK_KEX2_1	8	10	PF00082	0.492
CLV_PCSK_KEX2_1	932	934	PF00082	0.507
CLV_PCSK_PC1ET2_1	1004	1006	PF00082	0.291
CLV_PCSK_PC1ET2_1	1551	1553	PF00082	0.184
CLV_PCSK_PC1ET2_1	32	34	PF00082	0.308
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.303
CLV_PCSK_PC1ET2_1	624	626	PF00082	0.412
CLV_PCSK_PC1ET2_1	737	739	PF00082	0.267
CLV_PCSK_PC1ET2_1	750	752	PF00082	0.262
CLV_PCSK_PC1ET2_1	932	934	PF00082	0.502
CLV_PCSK_SKI1_1	1075	1079	PF00082	0.543
CLV_PCSK_SKI1_1	115	119	PF00082	0.448
CLV_PCSK_SKI1_1	120	124	PF00082	0.481
CLV_PCSK_SKI1_1	1429	1433	PF00082	0.438
CLV_PCSK_SKI1_1	1459	1463	PF00082	0.279
CLV_PCSK_SKI1_1	1511	1515	PF00082	0.325
CLV_PCSK_SKI1_1	1593	1597	PF00082	0.233
CLV_PCSK_SKI1_1	1703	1707	PF00082	0.394
CLV_PCSK_SKI1_1	286	290	PF00082	0.565
CLV_PCSK_SKI1_1	32	36	PF00082	0.319
CLV_PCSK_SKI1_1	377	381	PF00082	0.307
CLV_PCSK_SKI1_1	764	768	PF00082	0.253
CLV_PCSK_SKI1_1	883	887	PF00082	0.413
CLV_PCSK_SKI1_1	999	1003	PF00082	0.296
CLV_Separin_Metazoa	572	576	PF03568	0.655
CLV_Separin_Metazoa	974	978	PF03568	0.505
DEG_APCC_DBOX_1	1510	1518	PF00400	0.500
DEG_COP1_1	160	169	PF00400	0.236
DEG_Nend_UBRbox_1	1	4	PF02207	0.565
DEG_ODPH_VHL_1	467	479	PF01847	0.447
DOC_CKS1_1	1120	1125	PF01111	0.171
DOC_CKS1_1	49	54	PF01111	0.440
DOC_CKS1_1	560	565	PF01111	0.503
DOC_CYCLIN_RxL_1	115	126	PF00134	0.233
DOC_CYCLIN_RxL_1	30	41	PF00134	0.578
DOC_CYCLIN_RxL_1	376	388	PF00134	0.535
DOC_CYCLIN_yCln2_LP_2	118	124	PF00134	0.270
DOC_CYCLIN_yCln2_LP_2	485	491	PF00134	0.275
DOC_CYCLIN_yCln2_LP_2	49	55	PF00134	0.358
DOC_MAPK_FxFP_2	1039	1042	PF00069	0.155
DOC_MAPK_FxFP_2	367	370	PF00069	0.324
DOC_MAPK_gen_1	1102	1112	PF00069	0.287
DOC_MAPK_gen_1	1173	1180	PF00069	0.340
DOC_MAPK_gen_1	1579	1588	PF00069	0.460
DOC_MAPK_gen_1	223	229	PF00069	0.236
DOC_MAPK_gen_1	382	392	PF00069	0.484
DOC_MAPK_gen_1	621	629	PF00069	0.589
DOC_MAPK_gen_1	750	759	PF00069	0.467
DOC_MAPK_MEF2A_6	1037	1046	PF00069	0.300
DOC_MAPK_MEF2A_6	1579	1588	PF00069	0.460
DOC_MAPK_MEF2A_6	357	365	PF00069	0.406
DOC_MAPK_MEF2A_6	530	539	PF00069	0.356
DOC_MAPK_MEF2A_6	637	645	PF00069	0.494
DOC_MAPK_MEF2A_6	750	759	PF00069	0.461
DOC_MAPK_RevD_3	766	781	PF00069	0.519
DOC_PP1_RVXF_1	1457	1464	PF00149	0.462
DOC_PP1_RVXF_1	1591	1597	PF00149	0.464
DOC_PP1_RVXF_1	762	768	PF00149	0.486
DOC_PP2B_LxvP_1	1068	1071	PF13499	0.278
DOC_PP2B_LxvP_1	122	125	PF13499	0.251
DOC_PP2B_LxvP_1	337	340	PF13499	0.334
DOC_PP2B_LxvP_1	475	478	PF13499	0.308
DOC_PP2B_LxvP_1	936	939	PF13499	0.703
DOC_PP2B_PxIxI_1	359	365	PF00149	0.406
DOC_PP4_FxxP_1	1039	1042	PF00568	0.296
DOC_PP4_FxxP_1	1117	1120	PF00568	0.182
DOC_PP4_FxxP_1	1407	1410	PF00568	0.639
DOC_PP4_FxxP_1	1707	1710	PF00568	0.541
DOC_PP4_FxxP_1	367	370	PF00568	0.342
DOC_PP4_FxxP_1	495	498	PF00568	0.313
DOC_PP4_FxxP_1	876	879	PF00568	0.524
DOC_USP7_MATH_1	1071	1075	PF00917	0.305
DOC_USP7_MATH_1	1436	1440	PF00917	0.650
DOC_USP7_MATH_1	1620	1624	PF00917	0.532
DOC_USP7_MATH_1	1693	1697	PF00917	0.473
DOC_USP7_MATH_1	413	417	PF00917	0.406
DOC_USP7_MATH_1	80	84	PF00917	0.365
DOC_USP7_MATH_1	814	818	PF00917	0.493
DOC_USP7_MATH_1	948	952	PF00917	0.682
DOC_USP7_MATH_1	976	980	PF00917	0.629
DOC_USP7_UBL2_3	1656	1660	PF12436	0.570
DOC_WW_Pin1_4	1119	1124	PF00397	0.313
DOC_WW_Pin1_4	1138	1143	PF00397	0.329
DOC_WW_Pin1_4	1363	1368	PF00397	0.302
DOC_WW_Pin1_4	328	333	PF00397	0.344
DOC_WW_Pin1_4	48	53	PF00397	0.359
DOC_WW_Pin1_4	494	499	PF00397	0.251
DOC_WW_Pin1_4	525	530	PF00397	0.317
DOC_WW_Pin1_4	559	564	PF00397	0.505
DOC_WW_Pin1_4	941	946	PF00397	0.638
LIG_14-3-3_CanoR_1	1126	1133	PF00244	0.182
LIG_14-3-3_CanoR_1	1399	1407	PF00244	0.587
LIG_14-3-3_CanoR_1	1428	1432	PF00244	0.477
LIG_14-3-3_CanoR_1	1437	1444	PF00244	0.506
LIG_14-3-3_CanoR_1	1459	1464	PF00244	0.460
LIG_14-3-3_CanoR_1	1543	1548	PF00244	0.439
LIG_14-3-3_CanoR_1	1579	1585	PF00244	0.457
LIG_14-3-3_CanoR_1	161	169	PF00244	0.369
LIG_14-3-3_CanoR_1	1610	1619	PF00244	0.495
LIG_14-3-3_CanoR_1	1672	1680	PF00244	0.652
LIG_14-3-3_CanoR_1	1703	1708	PF00244	0.525
LIG_14-3-3_CanoR_1	192	197	PF00244	0.445
LIG_14-3-3_CanoR_1	223	231	PF00244	0.353
LIG_14-3-3_CanoR_1	424	428	PF00244	0.370
LIG_14-3-3_CanoR_1	462	470	PF00244	0.479
LIG_14-3-3_CanoR_1	751	756	PF00244	0.453
LIG_14-3-3_CanoR_1	780	785	PF00244	0.546
LIG_14-3-3_CanoR_1	8	16	PF00244	0.682
LIG_Actin_WH2_2	1635	1653	PF00022	0.521
LIG_Actin_WH2_2	1666	1683	PF00022	0.465
LIG_Actin_WH2_2	371	389	PF00022	0.290
LIG_Actin_WH2_2	411	426	PF00022	0.332
LIG_APCC_ABBA_1	1390	1395	PF00400	0.356
LIG_APCC_ABBA_1	536	541	PF00400	0.348
LIG_APCC_ABBA_1	548	553	PF00400	0.299
LIG_BIR_III_2	1411	1415	PF00653	0.628
LIG_BRCT_BRCA1_1	1068	1072	PF00533	0.244
LIG_BRCT_BRCA1_1	1288	1292	PF00533	0.329
LIG_BRCT_BRCA1_1	1688	1692	PF00533	0.594
LIG_BRCT_BRCA1_1	21	25	PF00533	0.617
LIG_BRCT_BRCA1_1	225	229	PF00533	0.325
LIG_BRCT_BRCA1_1	73	77	PF00533	0.386
LIG_BRCT_BRCA1_1	798	802	PF00533	0.446
LIG_BRCT_BRCA1_1	825	829	PF00533	0.529
LIG_BRCT_BRCA1_2	825	831	PF00533	0.525
LIG_Clathr_ClatBox_1	1109	1113	PF01394	0.174
LIG_Clathr_ClatBox_1	1441	1445	PF01394	0.428
LIG_Clathr_ClatBox_1	765	769	PF01394	0.461
LIG_CtBP_PxDLS_1	42	46	PF00389	0.522
LIG_EH1_1	1639	1647	PF00400	0.512
LIG_EH1_1	54	62	PF00400	0.356
LIG_eIF4E_1	1286	1292	PF01652	0.304
LIG_eIF4E_1	1387	1393	PF01652	0.411
LIG_eIF4E_1	401	407	PF01652	0.300
LIG_eIF4E_1	412	418	PF01652	0.216
LIG_FHA_1	101	107	PF00498	0.418
LIG_FHA_1	1105	1111	PF00498	0.279
LIG_FHA_1	1114	1120	PF00498	0.245
LIG_FHA_1	1133	1139	PF00498	0.299
LIG_FHA_1	1163	1169	PF00498	0.286
LIG_FHA_1	1243	1249	PF00498	0.323
LIG_FHA_1	1268	1274	PF00498	0.308
LIG_FHA_1	1307	1313	PF00498	0.315
LIG_FHA_1	1324	1330	PF00498	0.278
LIG_FHA_1	1389	1395	PF00498	0.363
LIG_FHA_1	1401	1407	PF00498	0.611
LIG_FHA_1	1460	1466	PF00498	0.462
LIG_FHA_1	1480	1486	PF00498	0.465
LIG_FHA_1	161	167	PF00498	0.359
LIG_FHA_1	1627	1633	PF00498	0.521
LIG_FHA_1	1704	1710	PF00498	0.521
LIG_FHA_1	1716	1722	PF00498	0.526
LIG_FHA_1	213	219	PF00498	0.318
LIG_FHA_1	321	327	PF00498	0.233
LIG_FHA_1	373	379	PF00498	0.359
LIG_FHA_1	580	586	PF00498	0.622
LIG_FHA_1	658	664	PF00498	0.473
LIG_FHA_1	781	787	PF00498	0.528
LIG_FHA_1	793	799	PF00498	0.480
LIG_FHA_1	83	89	PF00498	0.319
LIG_FHA_1	839	845	PF00498	0.542
LIG_FHA_1	941	947	PF00498	0.690
LIG_FHA_2	1051	1057	PF00498	0.271
LIG_FHA_2	1172	1178	PF00498	0.278
LIG_FHA_2	1529	1535	PF00498	0.466
LIG_FHA_2	1612	1618	PF00498	0.572
LIG_FHA_2	166	172	PF00498	0.336
LIG_FHA_2	1663	1669	PF00498	0.634
LIG_FHA_2	1737	1743	PF00498	0.563
LIG_FHA_2	211	217	PF00498	0.234
LIG_FHA_2	237	243	PF00498	0.359
LIG_FHA_2	249	255	PF00498	0.384
LIG_FHA_2	516	522	PF00498	0.244
LIG_FHA_2	700	706	PF00498	0.467
LIG_FHA_2	908	914	PF00498	0.530
LIG_GBD_Chelix_1	1304	1312	PF00786	0.391
LIG_GBD_Chelix_1	532	540	PF00786	0.342
LIG_LIR_Apic_2	1116	1120	PF02991	0.306
LIG_LIR_Apic_2	1706	1710	PF02991	0.526
LIG_LIR_Apic_2	205	210	PF02991	0.212
LIG_LIR_Apic_2	249	255	PF02991	0.399
LIG_LIR_Apic_2	494	498	PF02991	0.313
LIG_LIR_Apic_2	873	879	PF02991	0.548
LIG_LIR_Gen_1	1182	1193	PF02991	0.343
LIG_LIR_Gen_1	1245	1255	PF02991	0.312
LIG_LIR_Gen_1	1309	1319	PF02991	0.296
LIG_LIR_Gen_1	150	159	PF02991	0.278
LIG_LIR_Gen_1	1742	1752	PF02991	0.557
LIG_LIR_Gen_1	191	201	PF02991	0.387
LIG_LIR_Gen_1	22	31	PF02991	0.521
LIG_LIR_Gen_1	226	237	PF02991	0.347
LIG_LIR_Gen_1	308	318	PF02991	0.278
LIG_LIR_Gen_1	595	606	PF02991	0.666
LIG_LIR_Gen_1	702	712	PF02991	0.506
LIG_LIR_Gen_1	913	920	PF02991	0.532
LIG_LIR_Nem_3	1015	1020	PF02991	0.391
LIG_LIR_Nem_3	1048	1054	PF02991	0.272
LIG_LIR_Nem_3	1104	1109	PF02991	0.329
LIG_LIR_Nem_3	1182	1188	PF02991	0.268
LIG_LIR_Nem_3	1223	1229	PF02991	0.545
LIG_LIR_Nem_3	1245	1250	PF02991	0.280
LIG_LIR_Nem_3	1309	1314	PF02991	0.296
LIG_LIR_Nem_3	1469	1474	PF02991	0.463
LIG_LIR_Nem_3	1537	1542	PF02991	0.534
LIG_LIR_Nem_3	1742	1748	PF02991	0.548
LIG_LIR_Nem_3	191	196	PF02991	0.396
LIG_LIR_Nem_3	22	28	PF02991	0.551
LIG_LIR_Nem_3	225	231	PF02991	0.322
LIG_LIR_Nem_3	236	240	PF02991	0.330
LIG_LIR_Nem_3	308	313	PF02991	0.288
LIG_LIR_Nem_3	316	321	PF02991	0.292
LIG_LIR_Nem_3	348	354	PF02991	0.270
LIG_LIR_Nem_3	402	408	PF02991	0.329
LIG_LIR_Nem_3	431	436	PF02991	0.266
LIG_LIR_Nem_3	51	57	PF02991	0.297
LIG_LIR_Nem_3	541	545	PF02991	0.324
LIG_LIR_Nem_3	595	601	PF02991	0.651
LIG_LIR_Nem_3	702	707	PF02991	0.507
LIG_LIR_Nem_3	74	79	PF02991	0.336
LIG_LIR_Nem_3	783	787	PF02991	0.529
LIG_LIR_Nem_3	884	889	PF02991	0.595
LIG_LIR_Nem_3	913	919	PF02991	0.525
LIG_LYPXL_yS_3	1041	1044	PF13949	0.155
LIG_MAD2	324	332	PF02301	0.158
LIG_MLH1_MIPbox_1	225	229	PF16413	0.263
LIG_MLH1_MIPbox_1	73	77	PF16413	0.242
LIG_NRBOX	1024	1030	PF00104	0.300
LIG_PCNA_PIPBox_1	314	323	PF02747	0.297
LIG_PCNA_yPIPBox_3	1175	1188	PF02747	0.184
LIG_PCNA_yPIPBox_3	314	324	PF02747	0.357
LIG_Pex14_1	1231	1235	PF04695	0.318
LIG_Pex14_1	1375	1379	PF04695	0.371
LIG_Pex14_1	179	183	PF04695	0.374
LIG_Pex14_1	404	408	PF04695	0.365
LIG_Pex14_2	1117	1121	PF04695	0.210
LIG_Pex14_2	1227	1231	PF04695	0.481
LIG_Pex14_2	1307	1311	PF04695	0.327
LIG_Pex14_2	1663	1667	PF04695	0.653
LIG_Pex14_2	1688	1692	PF04695	0.569
LIG_Pex14_2	433	437	PF04695	0.246
LIG_Pex14_2	438	442	PF04695	0.256
LIG_PTB_Apo_2	1147	1154	PF02174	0.276
LIG_PTB_Apo_2	1231	1238	PF02174	0.344
LIG_PTB_Apo_2	1457	1464	PF02174	0.440
LIG_PTB_Phospho_1	1147	1153	PF10480	0.276
LIG_Rb_LxCxE_1	109	126	PF01857	0.409
LIG_Rb_LxCxE_1	1482	1500	PF01857	0.457
LIG_REV1ctd_RIR_1	455	464	PF16727	0.472
LIG_SH2_CRK	1051	1055	PF00017	0.263
LIG_SH2_CRK	1106	1110	PF00017	0.298
LIG_SH2_CRK	1185	1189	PF00017	0.335
LIG_SH2_CRK	1539	1543	PF00017	0.455
LIG_SH2_CRK	412	416	PF00017	0.402
LIG_SH2_CRK	710	714	PF00017	0.504
LIG_SH2_CRK	793	797	PF00017	0.404
LIG_SH2_GRB2like	1451	1454	PF00017	0.539
LIG_SH2_NCK_1	412	416	PF00017	0.414
LIG_SH2_PTP2	1387	1390	PF00017	0.414
LIG_SH2_SRC	231	234	PF00017	0.343
LIG_SH2_SRC	551	554	PF00017	0.402
LIG_SH2_SRC	671	674	PF00017	0.498
LIG_SH2_STAP1	1185	1189	PF00017	0.359
LIG_SH2_STAP1	1286	1290	PF00017	0.362
LIG_SH2_STAP1	147	151	PF00017	0.335
LIG_SH2_STAP1	401	405	PF00017	0.287
LIG_SH2_STAP1	608	612	PF00017	0.550
LIG_SH2_STAP1	704	708	PF00017	0.535
LIG_SH2_STAP1	905	909	PF00017	0.574
LIG_SH2_STAT3	1519	1522	PF00017	0.475
LIG_SH2_STAT3	408	411	PF00017	0.304
LIG_SH2_STAT3	690	693	PF00017	0.547
LIG_SH2_STAT5	1106	1109	PF00017	0.284
LIG_SH2_STAT5	1226	1229	PF00017	0.518
LIG_SH2_STAT5	1242	1245	PF00017	0.296
LIG_SH2_STAT5	1261	1264	PF00017	0.179
LIG_SH2_STAT5	1387	1390	PF00017	0.348
LIG_SH2_STAT5	1519	1522	PF00017	0.419
LIG_SH2_STAT5	1771	1774	PF00017	0.666
LIG_SH2_STAT5	207	210	PF00017	0.332
LIG_SH2_STAT5	221	224	PF00017	0.312
LIG_SH2_STAT5	228	231	PF00017	0.289
LIG_SH2_STAT5	293	296	PF00017	0.339
LIG_SH2_STAT5	305	308	PF00017	0.274
LIG_SH2_STAT5	320	323	PF00017	0.287
LIG_SH2_STAT5	401	404	PF00017	0.367
LIG_SH2_STAT5	408	411	PF00017	0.336
LIG_SH2_STAT5	427	430	PF00017	0.300
LIG_SH2_STAT5	472	475	PF00017	0.314
LIG_SH2_STAT5	524	527	PF00017	0.335
LIG_SH2_STAT5	545	548	PF00017	0.293
LIG_SH2_STAT5	551	554	PF00017	0.356
LIG_SH2_STAT5	671	674	PF00017	0.497
LIG_SH2_STAT5	690	693	PF00017	0.384
LIG_SH2_STAT5	76	79	PF00017	0.344
LIG_SH2_STAT5	782	785	PF00017	0.622
LIG_SH2_STAT5	838	841	PF00017	0.517
LIG_SH3_3	1076	1082	PF00018	0.193
LIG_SH3_3	1112	1118	PF00018	0.208
LIG_SH3_3	1370	1376	PF00018	0.270
LIG_SH3_3	1391	1397	PF00018	0.426
LIG_SH3_3	560	566	PF00018	0.525
LIG_SH3_3	972	978	PF00018	0.552
LIG_SH3_5	72	76	PF00018	0.406
LIG_SUMO_SIM_anti_2	1056	1061	PF11976	0.322
LIG_SUMO_SIM_anti_2	1482	1489	PF11976	0.449
LIG_SUMO_SIM_anti_2	444	449	PF11976	0.372
LIG_SUMO_SIM_anti_2	640	645	PF11976	0.477
LIG_SUMO_SIM_anti_2	811	817	PF11976	0.525
LIG_SUMO_SIM_anti_2	841	846	PF11976	0.570
LIG_SUMO_SIM_par_1	1053	1058	PF11976	0.302
LIG_SUMO_SIM_par_1	1251	1257	PF11976	0.317
LIG_SUMO_SIM_par_1	1318	1326	PF11976	0.336
LIG_SUMO_SIM_par_1	1528	1534	PF11976	0.488
LIG_SUMO_SIM_par_1	1555	1562	PF11976	0.516
LIG_SUMO_SIM_par_1	33	39	PF11976	0.447
LIG_SUMO_SIM_par_1	446	451	PF11976	0.337
LIG_SUMO_SIM_par_1	794	800	PF11976	0.481
LIG_SUMO_SIM_par_1	838	843	PF11976	0.540
LIG_TRAF2_1	719	722	PF00917	0.525
LIG_TRAF2_1	911	914	PF00917	0.553
LIG_TRFH_1	1707	1711	PF08558	0.555
LIG_TYR_ITIM	410	415	PF00017	0.393
LIG_TYR_ITIM	470	475	PF00017	0.306
LIG_TYR_ITIM	543	548	PF00017	0.263
LIG_UBA3_1	1028	1037	PF00899	0.314
LIG_UBA3_1	786	792	PF00899	0.566
LIG_WRC_WIRS_1	1340	1345	PF05994	0.340
LIG_WW_3	974	978	PF00397	0.510
MOD_CDK_SPK_2	525	530	PF00069	0.190
MOD_CDK_SPK_2	559	564	PF00069	0.512
MOD_CDK_SPxxK_3	1119	1126	PF00069	0.152
MOD_CK1_1	10	16	PF00069	0.699
MOD_CK1_1	1083	1089	PF00069	0.305
MOD_CK1_1	1162	1168	PF00069	0.294
MOD_CK1_1	1318	1324	PF00069	0.352
MOD_CK1_1	132	138	PF00069	0.372
MOD_CK1_1	1360	1366	PF00069	0.246
MOD_CK1_1	1737	1743	PF00069	0.560
MOD_CK1_1	1770	1776	PF00069	0.711
MOD_CK1_1	18	24	PF00069	0.648
MOD_CK1_1	186	192	PF00069	0.392
MOD_CK1_1	202	208	PF00069	0.315
MOD_CK1_1	212	218	PF00069	0.312
MOD_CK1_1	264	270	PF00069	0.438
MOD_CK1_1	308	314	PF00069	0.303
MOD_CK1_1	330	336	PF00069	0.294
MOD_CK1_1	372	378	PF00069	0.375
MOD_CK1_1	446	452	PF00069	0.320
MOD_CK1_1	494	500	PF00069	0.282
MOD_CK1_1	520	526	PF00069	0.288
MOD_CK1_1	903	909	PF00069	0.529
MOD_CK1_1	951	957	PF00069	0.648
MOD_CK2_1	1050	1056	PF00069	0.285
MOD_CK2_1	1171	1177	PF00069	0.261
MOD_CK2_1	1254	1260	PF00069	0.447
MOD_CK2_1	1318	1324	PF00069	0.357
MOD_CK2_1	1427	1433	PF00069	0.572
MOD_CK2_1	1528	1534	PF00069	0.462
MOD_CK2_1	1611	1617	PF00069	0.521
MOD_CK2_1	165	171	PF00069	0.350
MOD_CK2_1	1662	1668	PF00069	0.569
MOD_CK2_1	1672	1678	PF00069	0.572
MOD_CK2_1	1693	1699	PF00069	0.554
MOD_CK2_1	1736	1742	PF00069	0.555
MOD_CK2_1	210	216	PF00069	0.232
MOD_CK2_1	236	242	PF00069	0.370
MOD_CK2_1	699	705	PF00069	0.444
MOD_CK2_1	907	913	PF00069	0.534
MOD_Cter_Amidation	1397	1400	PF01082	0.418
MOD_Cter_Amidation	622	625	PF01082	0.431
MOD_GlcNHglycan	1063	1066	PF01048	0.454
MOD_GlcNHglycan	1082	1085	PF01048	0.525
MOD_GlcNHglycan	1128	1131	PF01048	0.438
MOD_GlcNHglycan	1135	1138	PF01048	0.446
MOD_GlcNHglycan	1222	1225	PF01048	0.268
MOD_GlcNHglycan	1279	1282	PF01048	0.330
MOD_GlcNHglycan	149	152	PF01048	0.587
MOD_GlcNHglycan	1573	1577	PF01048	0.264
MOD_GlcNHglycan	1598	1603	PF01048	0.273
MOD_GlcNHglycan	1726	1729	PF01048	0.420
MOD_GlcNHglycan	185	188	PF01048	0.644
MOD_GlcNHglycan	197	200	PF01048	0.491
MOD_GlcNHglycan	202	205	PF01048	0.477
MOD_GlcNHglycan	307	310	PF01048	0.446
MOD_GlcNHglycan	332	335	PF01048	0.565
MOD_GlcNHglycan	450	453	PF01048	0.357
MOD_GlcNHglycan	463	466	PF01048	0.349
MOD_GlcNHglycan	498	501	PF01048	0.474
MOD_GlcNHglycan	512	516	PF01048	0.521
MOD_GlcNHglycan	663	666	PF01048	0.291
MOD_GlcNHglycan	745	748	PF01048	0.266
MOD_GlcNHglycan	862	865	PF01048	0.364
MOD_GlcNHglycan	868	871	PF01048	0.383
MOD_GlcNHglycan	902	905	PF01048	0.367
MOD_GlcNHglycan	907	910	PF01048	0.342
MOD_GlcNHglycan	950	953	PF01048	0.495
MOD_GlcNHglycan	954	957	PF01048	0.500
MOD_GlcNHglycan	959	962	PF01048	0.450
MOD_GSK3_1	1066	1073	PF00069	0.292
MOD_GSK3_1	1082	1089	PF00069	0.247
MOD_GSK3_1	1133	1140	PF00069	0.212
MOD_GSK3_1	1159	1166	PF00069	0.224
MOD_GSK3_1	1167	1174	PF00069	0.271
MOD_GSK3_1	1195	1202	PF00069	0.318
MOD_GSK3_1	1318	1325	PF00069	0.327
MOD_GSK3_1	1357	1364	PF00069	0.232
MOD_GSK3_1	1445	1452	PF00069	0.613
MOD_GSK3_1	147	154	PF00069	0.311
MOD_GSK3_1	1479	1486	PF00069	0.469
MOD_GSK3_1	1493	1500	PF00069	0.462
MOD_GSK3_1	15	22	PF00069	0.598
MOD_GSK3_1	157	164	PF00069	0.384
MOD_GSK3_1	1580	1587	PF00069	0.494
MOD_GSK3_1	1621	1628	PF00069	0.533
MOD_GSK3_1	1688	1695	PF00069	0.551
MOD_GSK3_1	1732	1739	PF00069	0.588
MOD_GSK3_1	195	202	PF00069	0.323
MOD_GSK3_1	305	312	PF00069	0.272
MOD_GSK3_1	326	333	PF00069	0.282
MOD_GSK3_1	503	510	PF00069	0.231
MOD_GSK3_1	511	518	PF00069	0.219
MOD_GSK3_1	657	664	PF00069	0.498
MOD_GSK3_1	7	14	PF00069	0.684
MOD_GSK3_1	71	78	PF00069	0.375
MOD_GSK3_1	739	746	PF00069	0.463
MOD_GSK3_1	792	799	PF00069	0.509
MOD_GSK3_1	862	869	PF00069	0.607
MOD_GSK3_1	903	910	PF00069	0.552
MOD_GSK3_1	934	941	PF00069	0.658
MOD_GSK3_1	948	955	PF00069	0.578
MOD_N-GLC_1	1066	1071	PF02516	0.501
MOD_N-GLC_1	1124	1129	PF02516	0.480
MOD_N-GLC_1	1133	1138	PF02516	0.461
MOD_N-GLC_1	1159	1164	PF02516	0.485
MOD_N-GLC_1	1220	1225	PF02516	0.312
MOD_N-GLC_1	132	137	PF02516	0.632
MOD_N-GLC_1	1445	1450	PF02516	0.335
MOD_N-GLC_1	1459	1464	PF02516	0.208
MOD_N-GLC_1	161	166	PF02516	0.583
MOD_N-GLC_1	1621	1626	PF02516	0.352
MOD_N-GLC_1	264	269	PF02516	0.560
MOD_N-GLC_1	277	282	PF02516	0.500
MOD_N-GLC_1	699	704	PF02516	0.310
MOD_N-GLC_1	98	103	PF02516	0.538
MOD_NEK2_1	1031	1036	PF00069	0.329
MOD_NEK2_1	1050	1055	PF00069	0.258
MOD_NEK2_1	1066	1071	PF00069	0.258
MOD_NEK2_1	1094	1099	PF00069	0.289
MOD_NEK2_1	1225	1230	PF00069	0.442
MOD_NEK2_1	1315	1320	PF00069	0.339
MOD_NEK2_1	1323	1328	PF00069	0.276
MOD_NEK2_1	1357	1362	PF00069	0.282
MOD_NEK2_1	1473	1478	PF00069	0.458
MOD_NEK2_1	1688	1693	PF00069	0.468
MOD_NEK2_1	1764	1769	PF00069	0.682
MOD_NEK2_1	200	205	PF00069	0.351
MOD_NEK2_1	222	227	PF00069	0.301
MOD_NEK2_1	27	32	PF00069	0.517
MOD_NEK2_1	277	282	PF00069	0.296
MOD_NEK2_1	313	318	PF00069	0.324
MOD_NEK2_1	326	331	PF00069	0.258
MOD_NEK2_1	423	428	PF00069	0.273
MOD_NEK2_1	441	446	PF00069	0.212
MOD_NEK2_1	56	61	PF00069	0.361
MOD_NEK2_1	797	802	PF00069	0.516
MOD_NEK2_1	809	814	PF00069	0.543
MOD_NEK2_1	840	845	PF00069	0.526
MOD_NEK2_1	900	905	PF00069	0.546
MOD_NEK2_1	940	945	PF00069	0.748
MOD_NEK2_2	1242	1247	PF00069	0.408
MOD_NEK2_2	151	156	PF00069	0.219
MOD_NEK2_2	1693	1698	PF00069	0.581
MOD_NEK2_2	673	678	PF00069	0.484
MOD_NEK2_2	699	704	PF00069	0.512
MOD_PIKK_1	1012	1018	PF00454	0.564
MOD_PIKK_1	1400	1406	PF00454	0.639
MOD_PIKK_1	1734	1740	PF00454	0.557
MOD_PIKK_1	369	375	PF00454	0.347
MOD_PIKK_1	87	93	PF00454	0.354
MOD_PIKK_1	895	901	PF00454	0.587
MOD_PIKK_1	993	999	PF00454	0.506
MOD_PK_1	1580	1586	PF00069	0.473
MOD_PK_1	223	229	PF00069	0.244
MOD_PK_1	751	757	PF00069	0.466
MOD_PKA_1	1580	1586	PF00069	0.465
MOD_PKA_1	1703	1709	PF00069	0.607
MOD_PKA_1	223	229	PF00069	0.236
MOD_PKA_1	751	757	PF00069	0.471
MOD_PKA_1	780	786	PF00069	0.541
MOD_PKA_2	1104	1110	PF00069	0.270
MOD_PKA_2	1427	1433	PF00069	0.641
MOD_PKA_2	1436	1442	PF00069	0.507
MOD_PKA_2	1497	1503	PF00069	0.554
MOD_PKA_2	160	166	PF00069	0.284
MOD_PKA_2	1703	1709	PF00069	0.519
MOD_PKA_2	222	228	PF00069	0.386
MOD_PKA_2	423	429	PF00069	0.370
MOD_PKA_2	461	467	PF00069	0.466
MOD_PKA_2	7	13	PF00069	0.715
MOD_PKA_2	780	786	PF00069	0.541
MOD_PKA_2	895	901	PF00069	0.639
MOD_PKA_2	976	982	PF00069	0.590
MOD_PKB_1	1701	1709	PF00069	0.613
MOD_Plk_1	1066	1072	PF00069	0.290
MOD_Plk_1	1124	1130	PF00069	0.286
MOD_Plk_1	1159	1165	PF00069	0.316
MOD_Plk_1	1357	1363	PF00069	0.271
MOD_Plk_1	1459	1465	PF00069	0.412
MOD_Plk_1	161	167	PF00069	0.364
MOD_Plk_1	1620	1626	PF00069	0.552
MOD_Plk_1	1654	1660	PF00069	0.560
MOD_Plk_1	1732	1738	PF00069	0.595
MOD_Plk_1	18	24	PF00069	0.612
MOD_Plk_1	277	283	PF00069	0.310
MOD_Plk_1	520	526	PF00069	0.274
MOD_Plk_1	639	645	PF00069	0.492
MOD_Plk_1	699	705	PF00069	0.393
MOD_Plk_1	963	969	PF00069	0.641
MOD_Plk_1	98	104	PF00069	0.362
MOD_Plk_2-3	1427	1433	PF00069	0.588
MOD_Plk_2-3	1528	1534	PF00069	0.491
MOD_Plk_2-3	964	970	PF00069	0.578
MOD_Plk_4	1031	1037	PF00069	0.339
MOD_Plk_4	1050	1056	PF00069	0.225
MOD_Plk_4	1089	1095	PF00069	0.303
MOD_Plk_4	1159	1165	PF00069	0.312
MOD_Plk_4	1180	1186	PF00069	0.313
MOD_Plk_4	1200	1206	PF00069	0.193
MOD_Plk_4	123	129	PF00069	0.400
MOD_Plk_4	1267	1273	PF00069	0.302
MOD_Plk_4	1286	1292	PF00069	0.343
MOD_Plk_4	1315	1321	PF00069	0.338
MOD_Plk_4	1368	1374	PF00069	0.285
MOD_Plk_4	1388	1394	PF00069	0.317
MOD_Plk_4	1584	1590	PF00069	0.534
MOD_Plk_4	1621	1627	PF00069	0.532
MOD_Plk_4	202	208	PF00069	0.326
MOD_Plk_4	223	229	PF00069	0.329
MOD_Plk_4	313	319	PF00069	0.302
MOD_Plk_4	413	419	PF00069	0.349
MOD_Plk_4	423	429	PF00069	0.251
MOD_Plk_4	443	449	PF00069	0.222
MOD_Plk_4	503	509	PF00069	0.267
MOD_Plk_4	520	526	PF00069	0.246
MOD_Plk_4	56	62	PF00069	0.307
MOD_Plk_4	792	798	PF00069	0.531
MOD_Plk_4	840	846	PF00069	0.586
MOD_ProDKin_1	1119	1125	PF00069	0.313
MOD_ProDKin_1	1138	1144	PF00069	0.329
MOD_ProDKin_1	1363	1369	PF00069	0.302
MOD_ProDKin_1	328	334	PF00069	0.344
MOD_ProDKin_1	48	54	PF00069	0.359
MOD_ProDKin_1	494	500	PF00069	0.251
MOD_ProDKin_1	525	531	PF00069	0.317
MOD_ProDKin_1	559	565	PF00069	0.505
MOD_ProDKin_1	941	947	PF00069	0.637
MOD_SUMO_for_1	1355	1358	PF00179	0.328
MOD_SUMO_rev_2	1211	1216	PF00179	0.493
TRG_DiLeu_BaEn_1	214	219	PF01217	0.393
TRG_DiLeu_BaEn_1	640	645	PF01217	0.489
TRG_DiLeu_BaEn_2	112	118	PF01217	0.249
TRG_DiLeu_BaEn_2	1468	1474	PF01217	0.466
TRG_DiLeu_BaEn_4	1633	1639	PF01217	0.526
TRG_DiLeu_BaEn_4	1759	1765	PF01217	0.648
TRG_DiLeu_BaLyEn_6	177	182	PF01217	0.365
TRG_DiLeu_BaLyEn_6	357	362	PF01217	0.363
TRG_DiLeu_BaLyEn_6	466	471	PF01217	0.354
TRG_ENDOCYTIC_2	1041	1044	PF00928	0.357
TRG_ENDOCYTIC_2	1051	1054	PF00928	0.334
TRG_ENDOCYTIC_2	1106	1109	PF00928	0.275
TRG_ENDOCYTIC_2	1185	1188	PF00928	0.359
TRG_ENDOCYTIC_2	1226	1229	PF00928	0.528
TRG_ENDOCYTIC_2	1387	1390	PF00928	0.351
TRG_ENDOCYTIC_2	152	155	PF00928	0.403
TRG_ENDOCYTIC_2	1539	1542	PF00928	0.465
TRG_ENDOCYTIC_2	318	321	PF00928	0.299
TRG_ENDOCYTIC_2	412	415	PF00928	0.394
TRG_ENDOCYTIC_2	472	475	PF00928	0.322
TRG_ENDOCYTIC_2	545	548	PF00928	0.295
TRG_ENDOCYTIC_2	633	636	PF00928	0.492
TRG_ENDOCYTIC_2	704	707	PF00928	0.488
TRG_ENDOCYTIC_2	710	713	PF00928	0.480
TRG_ENDOCYTIC_2	76	79	PF00928	0.371
TRG_ENDOCYTIC_2	793	796	PF00928	0.551
TRG_ER_diArg_1	1399	1402	PF00400	0.590
TRG_ER_diArg_1	1550	1553	PF00400	0.495
TRG_ER_diArg_1	1671	1674	PF00400	0.614
TRG_ER_diArg_1	1700	1703	PF00400	0.668
TRG_ER_diArg_1	384	387	PF00400	0.492
TRG_ER_diArg_1	780	782	PF00400	0.617
TRG_NES_CRM1_1	1347	1359	PF08389	0.335
TRG_NES_CRM1_1	26	41	PF08389	0.576
TRG_NES_CRM1_1	541	553	PF08389	0.295
TRG_NES_CRM1_1	723	736	PF08389	0.534
TRG_NLS_Bipartite_1	737	754	PF00514	0.411
TRG_NLS_MonoExtC_3	1549	1555	PF00514	0.384
TRG_Pf-PMV_PEXEL_1	1011	1016	PF00026	0.264
TRG_Pf-PMV_PEXEL_1	1651	1655	PF00026	0.374
TRG_Pf-PMV_PEXEL_1	180	184	PF00026	0.585
TRG_Pf-PMV_PEXEL_1	33	38	PF00026	0.340

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K1Q8	Rattus norvegicus	32%	100%
A0A0N0P411	Leptomonas seymouri	47%	89%
A0A0N1I1A6	Leptomonas seymouri	30%	95%
A0A0N1IH55	Leptomonas seymouri	68%	95%
A0A0S4IQH9	Bodo saltans	34%	93%
A0A0S4IUV3	Bodo saltans	50%	96%
A0A0S4IZR8	Bodo saltans	41%	100%
A0A0S4J5Z1	Bodo saltans	49%	97%
A0A0S4J9S9	Bodo saltans	40%	97%
A0A0S4JDK3	Bodo saltans	39%	94%
A0A0S4JTU9	Bodo saltans	35%	96%
A0A1X0NJG3	Trypanosomatidae	49%	99%
A0A1X0NUW1	Trypanosomatidae	45%	100%
A0A1X0NV41	Trypanosomatidae	56%	100%
A0A1X0NZH7	Trypanosomatidae	30%	93%
A0A3Q8I827	Leishmania donovani	98%	94%
A0A3Q8I970	Leishmania donovani	48%	94%
A0A3Q8IBC5	Leishmania donovani	45%	99%
A0A3Q8IHK0	Leishmania donovani	48%	100%
A0A3R7NVN7	Trypanosoma rangeli	49%	100%
A0A3S7WRQ5	Leishmania donovani	98%	100%
A0A3S7X0K7	Leishmania donovani	55%	96%
A0A3S7X0L1	Leishmania donovani	55%	95%
A0A3S7X267	Leishmania donovani	30%	95%
A0A422NUL9	Trypanosoma rangeli	29%	95%
A4H6P2	Leishmania braziliensis	74%	100%
A4H6P6	Leishmania braziliensis	44%	100%
A4H6P7	Leishmania braziliensis	44%	100%
A4H6P8	Leishmania braziliensis	48%	99%
A4H6Q0	Leishmania braziliensis	47%	100%
A4HFM0	Leishmania braziliensis	56%	100%
A4HH69	Leishmania braziliensis	30%	100%
A4HV31	Leishmania infantum	45%	98%
A4HV32	Leishmania infantum	94%	94%
A4HV33	Leishmania infantum	48%	100%
A4HV35	Leishmania infantum	48%	94%
A4I2P8	Leishmania infantum	55%	96%
A4I4B4	Leishmania infantum	30%	95%
C9ZL54	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	96%
D0A7B9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
E9AD74	Leishmania major	55%	100%
E9AD75	Leishmania major	55%	100%
E9ADR4	Leishmania major	30%	100%
E9AM16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ANR1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
E9ANR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9ANR4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9ANR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9AYZ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
E9PU17	Rattus norvegicus	30%	100%
E9PX95	Mus musculus	29%	100%
P34358	Caenorhabditis elegans	28%	100%
Q4QGV3	Leishmania major	48%	100%
Q4QGV5	Leishmania major	47%	100%
Q4QGV7	Leishmania major	89%	100%
Q4QGV8	Leishmania major	44%	100%
Q4QGW0	Leishmania major	89%	100%
Q54BT5	Dictyostelium discoideum	27%	100%
Q555Z5	Dictyostelium discoideum	28%	100%
Q84M24	Arabidopsis thaliana	31%	94%
Q8R420	Mus musculus	32%	100%
Q8T6J1	Dictyostelium discoideum	28%	100%
Q8T6J2	Dictyostelium discoideum	27%	100%
Q8T6J5	Dictyostelium discoideum	28%	100%
Q99758	Homo sapiens	32%	100%
V5B4J7	Trypanosoma cruzi	44%	100%
V5BWI9	Trypanosoma cruzi	44%	100%