RRM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HV13_LEIIN

TriTrypDb:

LINF_110016400

Length:

814

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HV13

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HV13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	380	384	PF00656	0.770
CLV_C14_Caspase3-7	518	522	PF00656	0.726
CLV_NRD_NRD_1	306	308	PF00675	0.624
CLV_NRD_NRD_1	459	461	PF00675	0.765
CLV_NRD_NRD_1	792	794	PF00675	0.632
CLV_PCSK_KEX2_1	306	308	PF00082	0.550
CLV_PCSK_KEX2_1	459	461	PF00082	0.765
CLV_PCSK_KEX2_1	512	514	PF00082	0.621
CLV_PCSK_PC1ET2_1	512	514	PF00082	0.621
CLV_PCSK_SKI1_1	218	222	PF00082	0.552
CLV_PCSK_SKI1_1	225	229	PF00082	0.503
CLV_PCSK_SKI1_1	563	567	PF00082	0.686
CLV_PCSK_SKI1_1	601	605	PF00082	0.763
CLV_PCSK_SKI1_1	738	742	PF00082	0.618
CLV_PCSK_SKI1_1	764	768	PF00082	0.652
CLV_PCSK_SKI1_1	797	801	PF00082	0.631
CLV_PCSK_SKI1_1	96	100	PF00082	0.741
DEG_SPOP_SBC_1	10	14	PF00917	0.652
DEG_SPOP_SBC_1	134	138	PF00917	0.745
DEG_SPOP_SBC_1	234	238	PF00917	0.685
DEG_SPOP_SBC_1	493	497	PF00917	0.741
DEG_SPOP_SBC_1	584	588	PF00917	0.732
DEG_SPOP_SBC_1	619	623	PF00917	0.768
DOC_CKS1_1	447	452	PF01111	0.681
DOC_CKS1_1	640	645	PF01111	0.764
DOC_MAPK_gen_1	199	208	PF00069	0.546
DOC_MAPK_gen_1	793	801	PF00069	0.637
DOC_PP1_RVXF_1	202	209	PF00149	0.630
DOC_PP1_RVXF_1	785	792	PF00149	0.615
DOC_PP2B_LxvP_1	53	56	PF13499	0.658
DOC_PP2B_LxvP_1	645	648	PF13499	0.660
DOC_PP2B_LxvP_1	701	704	PF13499	0.699
DOC_PP2B_LxvP_1	767	770	PF13499	0.708
DOC_PP4_FxxP_1	239	242	PF00568	0.690
DOC_PP4_FxxP_1	32	35	PF00568	0.592
DOC_PP4_FxxP_1	573	576	PF00568	0.737
DOC_PP4_FxxP_1	766	769	PF00568	0.679
DOC_USP7_MATH_1	134	138	PF00917	0.745
DOC_USP7_MATH_1	153	157	PF00917	0.521
DOC_USP7_MATH_1	244	248	PF00917	0.828
DOC_USP7_MATH_1	278	282	PF00917	0.687
DOC_USP7_MATH_1	334	338	PF00917	0.759
DOC_USP7_MATH_1	511	515	PF00917	0.716
DOC_USP7_MATH_1	552	556	PF00917	0.759
DOC_USP7_MATH_1	559	563	PF00917	0.760
DOC_USP7_MATH_1	697	701	PF00917	0.703
DOC_USP7_MATH_1	80	84	PF00917	0.823
DOC_USP7_MATH_1	92	96	PF00917	0.612
DOC_WW_Pin1_4	154	159	PF00397	0.764
DOC_WW_Pin1_4	274	279	PF00397	0.826
DOC_WW_Pin1_4	281	286	PF00397	0.483
DOC_WW_Pin1_4	31	36	PF00397	0.646
DOC_WW_Pin1_4	339	344	PF00397	0.732
DOC_WW_Pin1_4	346	351	PF00397	0.698
DOC_WW_Pin1_4	405	410	PF00397	0.790
DOC_WW_Pin1_4	415	420	PF00397	0.652
DOC_WW_Pin1_4	446	451	PF00397	0.806
DOC_WW_Pin1_4	45	50	PF00397	0.594
DOC_WW_Pin1_4	452	457	PF00397	0.784
DOC_WW_Pin1_4	639	644	PF00397	0.762
DOC_WW_Pin1_4	674	679	PF00397	0.803
DOC_WW_Pin1_4	680	685	PF00397	0.716
DOC_WW_Pin1_4	729	734	PF00397	0.775
DOC_WW_Pin1_4	81	86	PF00397	0.680
LIG_14-3-3_CanoR_1	113	117	PF00244	0.675
LIG_14-3-3_CanoR_1	148	154	PF00244	0.797
LIG_14-3-3_CanoR_1	197	206	PF00244	0.573
LIG_14-3-3_CanoR_1	306	311	PF00244	0.518
LIG_14-3-3_CanoR_1	393	399	PF00244	0.632
LIG_14-3-3_CanoR_1	460	470	PF00244	0.831
LIG_14-3-3_CanoR_1	545	550	PF00244	0.642
LIG_14-3-3_CanoR_1	553	558	PF00244	0.576
LIG_14-3-3_CanoR_1	636	645	PF00244	0.722
LIG_14-3-3_CanoR_1	742	748	PF00244	0.630
LIG_14-3-3_CanoR_1	87	93	PF00244	0.651
LIG_BIR_II_1	1	5	PF00653	0.679
LIG_BIR_III_4	574	578	PF00653	0.676
LIG_BIR_III_4	63	67	PF00653	0.796
LIG_BRCT_BRCA1_1	270	274	PF00533	0.829
LIG_BRCT_BRCA1_1	32	36	PF00533	0.808
LIG_BRCT_BRCA1_1	753	757	PF00533	0.607
LIG_CSL_BTD_1	411	414	PF09270	0.770
LIG_deltaCOP1_diTrp_1	118	125	PF00928	0.705
LIG_FHA_1	106	112	PF00498	0.776
LIG_FHA_1	166	172	PF00498	0.443
LIG_FHA_1	292	298	PF00498	0.511
LIG_FHA_1	4	10	PF00498	0.630
LIG_FHA_1	456	462	PF00498	0.756
LIG_FHA_1	562	568	PF00498	0.701
LIG_FHA_1	603	609	PF00498	0.761
LIG_FHA_1	633	639	PF00498	0.772
LIG_FHA_1	640	646	PF00498	0.693
LIG_FHA_1	654	660	PF00498	0.507
LIG_FHA_1	681	687	PF00498	0.851
LIG_FHA_2	282	288	PF00498	0.482
LIG_LIR_Apic_2	122	128	PF02991	0.726
LIG_LIR_Apic_2	236	242	PF02991	0.659
LIG_LIR_Apic_2	30	35	PF02991	0.589
LIG_LIR_Apic_2	548	552	PF02991	0.601
LIG_LIR_Apic_2	765	769	PF02991	0.672
LIG_LIR_Gen_1	136	147	PF02991	0.749
LIG_LIR_Gen_1	383	392	PF02991	0.769
LIG_LIR_Gen_1	564	573	PF02991	0.670
LIG_LIR_Gen_1	695	705	PF02991	0.624
LIG_LIR_Nem_3	136	142	PF02991	0.829
LIG_LIR_Nem_3	287	291	PF02991	0.574
LIG_LIR_Nem_3	33	39	PF02991	0.815
LIG_LIR_Nem_3	383	388	PF02991	0.675
LIG_LIR_Nem_3	564	569	PF02991	0.659
LIG_LIR_Nem_3	695	701	PF02991	0.630
LIG_LIR_Nem_3	737	743	PF02991	0.688
LIG_LIR_Nem_3	754	760	PF02991	0.335
LIG_Pex14_2	32	36	PF04695	0.594
LIG_Pex14_2	502	506	PF04695	0.657
LIG_Pex14_2	753	757	PF04695	0.607
LIG_PTAP_UEV_1	466	471	PF05743	0.649
LIG_REV1ctd_RIR_1	738	746	PF16727	0.668
LIG_SH2_CRK	211	215	PF00017	0.605
LIG_SH2_CRK	385	389	PF00017	0.675
LIG_SH2_CRK	698	702	PF00017	0.712
LIG_SH2_NCK_1	120	124	PF00017	0.705
LIG_SH2_NCK_1	211	215	PF00017	0.605
LIG_SH2_NCK_1	385	389	PF00017	0.675
LIG_SH2_PTP2	187	190	PF00017	0.518
LIG_SH2_SRC	187	190	PF00017	0.518
LIG_SH2_STAP1	120	124	PF00017	0.705
LIG_SH2_STAP1	211	215	PF00017	0.605
LIG_SH2_STAP1	288	292	PF00017	0.653
LIG_SH2_STAP1	625	629	PF00017	0.773
LIG_SH2_STAT3	578	581	PF00017	0.701
LIG_SH2_STAT5	187	190	PF00017	0.518
LIG_SH2_STAT5	291	294	PF00017	0.643
LIG_SH2_STAT5	578	581	PF00017	0.779
LIG_SH2_STAT5	752	755	PF00017	0.602
LIG_SH3_1	524	530	PF00018	0.765
LIG_SH3_2	531	536	PF14604	0.639
LIG_SH3_2	558	563	PF14604	0.791
LIG_SH3_2	631	636	PF14604	0.628
LIG_SH3_3	155	161	PF00018	0.771
LIG_SH3_3	183	189	PF00018	0.603
LIG_SH3_3	272	278	PF00018	0.715
LIG_SH3_3	344	350	PF00018	0.787
LIG_SH3_3	354	360	PF00018	0.650
LIG_SH3_3	385	391	PF00018	0.688
LIG_SH3_3	399	405	PF00018	0.732
LIG_SH3_3	416	422	PF00018	0.747
LIG_SH3_3	441	447	PF00018	0.680
LIG_SH3_3	464	470	PF00018	0.751
LIG_SH3_3	497	503	PF00018	0.757
LIG_SH3_3	524	530	PF00018	0.839
LIG_SH3_3	555	561	PF00018	0.810
LIG_SH3_3	603	609	PF00018	0.743
LIG_SH3_3	613	619	PF00018	0.682
LIG_SH3_3	628	634	PF00018	0.642
LIG_SUMO_SIM_par_1	106	112	PF11976	0.721
LIG_SUMO_SIM_par_1	226	232	PF11976	0.538
LIG_UBA3_1	227	231	PF00899	0.528
LIG_WW_1	769	772	PF00397	0.699
LIG_WW_2	558	561	PF00397	0.792
MOD_CDK_SPxK_1	81	87	PF00069	0.653
MOD_CDK_SPxxK_3	452	459	PF00069	0.764
MOD_CDK_SPxxK_3	680	687	PF00069	0.850
MOD_CK1_1	104	110	PF00069	0.700
MOD_CK1_1	129	135	PF00069	0.810
MOD_CK1_1	137	143	PF00069	0.699
MOD_CK1_1	157	163	PF00069	0.527
MOD_CK1_1	281	287	PF00069	0.502
MOD_CK1_1	318	324	PF00069	0.737
MOD_CK1_1	338	344	PF00069	0.545
MOD_CK1_1	386	392	PF00069	0.768
MOD_CK1_1	445	451	PF00069	0.771
MOD_CK1_1	45	51	PF00069	0.835
MOD_CK1_1	455	461	PF00069	0.759
MOD_CK1_1	465	471	PF00069	0.583
MOD_CK1_1	58	64	PF00069	0.616
MOD_CK1_1	587	593	PF00069	0.767
MOD_CK1_1	639	645	PF00069	0.815
MOD_CK1_1	674	680	PF00069	0.758
MOD_CK1_1	707	713	PF00069	0.802
MOD_CK1_1	729	735	PF00069	0.689
MOD_CK1_1	78	84	PF00069	0.494
MOD_CK2_1	274	280	PF00069	0.823
MOD_CK2_1	281	287	PF00069	0.478
MOD_GlcNHglycan	246	249	PF01048	0.833
MOD_GlcNHglycan	261	265	PF01048	0.562
MOD_GlcNHglycan	464	467	PF01048	0.752
MOD_GlcNHglycan	593	596	PF01048	0.813
MOD_GlcNHglycan	60	63	PF01048	0.831
MOD_GlcNHglycan	650	653	PF01048	0.808
MOD_GlcNHglycan	660	663	PF01048	0.575
MOD_GlcNHglycan	80	83	PF01048	0.491
MOD_GlcNHglycan	88	91	PF01048	0.744
MOD_GSK3_1	129	136	PF00069	0.811
MOD_GSK3_1	153	160	PF00069	0.775
MOD_GSK3_1	161	168	PF00069	0.512
MOD_GSK3_1	244	251	PF00069	0.826
MOD_GSK3_1	27	34	PF00069	0.493
MOD_GSK3_1	274	281	PF00069	0.592
MOD_GSK3_1	334	341	PF00069	0.769
MOD_GSK3_1	342	349	PF00069	0.683
MOD_GSK3_1	38	45	PF00069	0.632
MOD_GSK3_1	442	449	PF00069	0.706
MOD_GSK3_1	461	468	PF00069	0.675
MOD_GSK3_1	583	590	PF00069	0.825
MOD_GSK3_1	608	615	PF00069	0.842
MOD_GSK3_1	632	639	PF00069	0.806
MOD_GSK3_1	672	679	PF00069	0.808
MOD_GSK3_1	692	699	PF00069	0.536
MOD_GSK3_1	703	710	PF00069	0.610
MOD_GSK3_1	9	16	PF00069	0.656
MOD_GSK3_1	97	104	PF00069	0.775
MOD_LATS_1	551	557	PF00433	0.630
MOD_LATS_1	599	605	PF00433	0.726
MOD_N-GLC_1	808	813	PF02516	0.696
MOD_NEK2_1	105	110	PF00069	0.757
MOD_NEK2_1	3	8	PF00069	0.716
MOD_NEK2_1	658	663	PF00069	0.615
MOD_NEK2_1	743	748	PF00069	0.587
MOD_NEK2_1	9	14	PF00069	0.731
MOD_NEK2_2	561	566	PF00069	0.730
MOD_PIKK_1	291	297	PF00454	0.647
MOD_PIKK_1	318	324	PF00454	0.704
MOD_PIKK_1	38	44	PF00454	0.743
MOD_PIKK_1	383	389	PF00454	0.772
MOD_PIKK_1	636	642	PF00454	0.762
MOD_PIKK_1	692	698	PF00454	0.777
MOD_PIKK_1	704	710	PF00454	0.693
MOD_PKA_1	306	312	PF00069	0.525
MOD_PKA_2	112	118	PF00069	0.771
MOD_PKA_2	147	153	PF00069	0.683
MOD_PKA_2	248	254	PF00069	0.708
MOD_PKA_2	27	33	PF00069	0.600
MOD_PKA_2	306	312	PF00069	0.447
MOD_PKA_2	552	558	PF00069	0.623
MOD_PKA_2	58	64	PF00069	0.831
MOD_PKA_2	584	590	PF00069	0.818
MOD_PKA_2	692	698	PF00069	0.621
MOD_PKA_2	86	92	PF00069	0.652
MOD_Plk_1	72	78	PF00069	0.638
MOD_Plk_1	808	814	PF00069	0.713
MOD_Plk_2-3	112	118	PF00069	0.771
MOD_Plk_4	165	171	PF00069	0.463
MOD_Plk_4	219	225	PF00069	0.457
MOD_Plk_4	27	33	PF00069	0.623
MOD_Plk_4	300	306	PF00069	0.610
MOD_Plk_4	743	749	PF00069	0.621
MOD_ProDKin_1	154	160	PF00069	0.756
MOD_ProDKin_1	274	280	PF00069	0.823
MOD_ProDKin_1	281	287	PF00069	0.478
MOD_ProDKin_1	31	37	PF00069	0.649
MOD_ProDKin_1	339	345	PF00069	0.734
MOD_ProDKin_1	346	352	PF00069	0.699
MOD_ProDKin_1	405	411	PF00069	0.793
MOD_ProDKin_1	415	421	PF00069	0.652
MOD_ProDKin_1	446	452	PF00069	0.807
MOD_ProDKin_1	45	51	PF00069	0.596
MOD_ProDKin_1	639	645	PF00069	0.762
MOD_ProDKin_1	674	680	PF00069	0.804
MOD_ProDKin_1	685	691	PF00069	0.630
MOD_ProDKin_1	729	735	PF00069	0.766
MOD_ProDKin_1	81	87	PF00069	0.682
TRG_AP2beta_CARGO_1	755	764	PF09066	0.617
TRG_DiLeu_BaLyEn_6	565	570	PF01217	0.655
TRG_DiLeu_BaLyEn_6	654	659	PF01217	0.718
TRG_ENDOCYTIC_2	211	214	PF00928	0.605
TRG_ENDOCYTIC_2	385	388	PF00928	0.773
TRG_ENDOCYTIC_2	698	701	PF00928	0.714
TRG_ENDOCYTIC_2	763	766	PF00928	0.616
TRG_ER_diArg_1	305	307	PF00400	0.548
TRG_ER_diArg_1	459	461	PF00400	0.765
TRG_ER_diArg_1	56	59	PF00400	0.835
TRG_ER_diArg_1	93	96	PF00400	0.733
TRG_NES_CRM1_1	219	232	PF08389	0.524
TRG_Pf-PMV_PEXEL_1	317	322	PF00026	0.634

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IBB5	Leishmania donovani	99%	100%
A4H6N0	Leishmania braziliensis	64%	100%
E9ANP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QGX5	Leishmania major	87%	100%