PUB domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PUB domain containing protein - putative

Species:

Leishmania infantum

UniProt:

A4HV01_LEIIN

TriTrypDb:

LINF_110014900

Length:

620

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HV01

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HV01

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	112	116	PF00656	0.721
CLV_C14_Caspase3-7	370	374	PF00656	0.618
CLV_C14_Caspase3-7	477	481	PF00656	0.570
CLV_NRD_NRD_1	19	21	PF00675	0.563
CLV_NRD_NRD_1	200	202	PF00675	0.398
CLV_NRD_NRD_1	287	289	PF00675	0.515
CLV_NRD_NRD_1	496	498	PF00675	0.636
CLV_NRD_NRD_1	528	530	PF00675	0.653
CLV_NRD_NRD_1	553	555	PF00675	0.641
CLV_NRD_NRD_1	564	566	PF00675	0.696
CLV_NRD_NRD_1	611	613	PF00675	0.650
CLV_PCSK_FUR_1	494	498	PF00082	0.636
CLV_PCSK_FUR_1	526	530	PF00082	0.710
CLV_PCSK_KEX2_1	19	21	PF00082	0.563
CLV_PCSK_KEX2_1	200	202	PF00082	0.334
CLV_PCSK_KEX2_1	287	289	PF00082	0.567
CLV_PCSK_KEX2_1	496	498	PF00082	0.556
CLV_PCSK_KEX2_1	523	525	PF00082	0.541
CLV_PCSK_KEX2_1	528	530	PF00082	0.564
CLV_PCSK_KEX2_1	552	554	PF00082	0.641
CLV_PCSK_KEX2_1	564	566	PF00082	0.699
CLV_PCSK_KEX2_1	611	613	PF00082	0.690
CLV_PCSK_PC1ET2_1	523	525	PF00082	0.590
CLV_PCSK_PC7_1	519	525	PF00082	0.695
CLV_PCSK_PC7_1	549	555	PF00082	0.741
CLV_PCSK_PC7_1	560	566	PF00082	0.661
CLV_PCSK_SKI1_1	13	17	PF00082	0.588
CLV_PCSK_SKI1_1	159	163	PF00082	0.585
CLV_PCSK_SKI1_1	25	29	PF00082	0.727
CLV_PCSK_SKI1_1	59	63	PF00082	0.521
CLV_PCSK_SKI1_1	64	68	PF00082	0.550
DEG_SCF_FBW7_1	475	482	PF00400	0.684
DEG_SPOP_SBC_1	29	33	PF00917	0.541
DEG_SPOP_SBC_1	456	460	PF00917	0.625
DEG_SPOP_SBC_1	568	572	PF00917	0.787
DEG_SPOP_SBC_1	614	618	PF00917	0.809
DOC_MAPK_MEF2A_6	296	304	PF00069	0.598
DOC_MAPK_MEF2A_6	422	429	PF00069	0.518
DOC_PP2B_LxvP_1	120	123	PF13499	0.809
DOC_PP4_FxxP_1	436	439	PF00568	0.689
DOC_USP7_MATH_1	103	107	PF00917	0.671
DOC_USP7_MATH_1	125	129	PF00917	0.748
DOC_USP7_MATH_1	138	142	PF00917	0.571
DOC_USP7_MATH_1	154	158	PF00917	0.444
DOC_USP7_MATH_1	161	165	PF00917	0.733
DOC_USP7_MATH_1	217	221	PF00917	0.524
DOC_USP7_MATH_1	238	242	PF00917	0.720
DOC_USP7_MATH_1	29	33	PF00917	0.541
DOC_USP7_MATH_1	343	347	PF00917	0.718
DOC_USP7_MATH_1	400	404	PF00917	0.614
DOC_USP7_MATH_1	449	453	PF00917	0.714
DOC_USP7_MATH_1	456	460	PF00917	0.658
DOC_USP7_MATH_1	479	483	PF00917	0.671
DOC_USP7_MATH_1	514	518	PF00917	0.594
DOC_USP7_MATH_1	566	570	PF00917	0.825
DOC_USP7_MATH_1	80	84	PF00917	0.611
DOC_USP7_MATH_1	91	95	PF00917	0.718
DOC_WW_Pin1_4	121	126	PF00397	0.689
DOC_WW_Pin1_4	127	132	PF00397	0.726
DOC_WW_Pin1_4	240	245	PF00397	0.565
DOC_WW_Pin1_4	312	317	PF00397	0.720
DOC_WW_Pin1_4	350	355	PF00397	0.751
DOC_WW_Pin1_4	457	462	PF00397	0.632
DOC_WW_Pin1_4	475	480	PF00397	0.473
DOC_WW_Pin1_4	604	609	PF00397	0.616
DOC_WW_Pin1_4	615	620	PF00397	0.640
DOC_WW_Pin1_4	87	92	PF00397	0.750
DOC_WW_Pin1_4	94	99	PF00397	0.756
LIG_14-3-3_CanoR_1	13	18	PF00244	0.564
LIG_14-3-3_CanoR_1	140	145	PF00244	0.621
LIG_14-3-3_CanoR_1	592	602	PF00244	0.612
LIG_BIR_III_4	115	119	PF00653	0.723
LIG_BRCT_BRCA1_1	140	144	PF00533	0.681
LIG_CaM_IQ_9	489	505	PF13499	0.565
LIG_deltaCOP1_diTrp_1	145	151	PF00928	0.516
LIG_EVH1_2	169	173	PF00568	0.612
LIG_FHA_1	151	157	PF00498	0.641
LIG_FHA_1	409	415	PF00498	0.614
LIG_FHA_1	441	447	PF00498	0.757
LIG_FHA_1	468	474	PF00498	0.686
LIG_FHA_1	594	600	PF00498	0.602
LIG_FHA_2	110	116	PF00498	0.741
LIG_FHA_2	141	147	PF00498	0.552
LIG_FHA_2	365	371	PF00498	0.545
LIG_FHA_2	463	469	PF00498	0.750
LIG_FHA_2	49	55	PF00498	0.547
LIG_LIR_Gen_1	108	116	PF02991	0.589
LIG_LIR_Gen_1	249	258	PF02991	0.437
LIG_LIR_Gen_1	373	382	PF02991	0.515
LIG_LIR_Nem_3	145	150	PF02991	0.522
LIG_LIR_Nem_3	196	202	PF02991	0.384
LIG_LIR_Nem_3	225	229	PF02991	0.474
LIG_LIR_Nem_3	249	253	PF02991	0.408
LIG_LIR_Nem_3	413	418	PF02991	0.536
LIG_NRBOX	182	188	PF00104	0.513
LIG_SH2_CRK	199	203	PF00017	0.411
LIG_SH2_CRK	415	419	PF00017	0.514
LIG_SH2_NCK_1	389	393	PF00017	0.633
LIG_SH2_SRC	389	392	PF00017	0.555
LIG_SH2_STAP1	389	393	PF00017	0.633
LIG_SH2_STAP1	469	473	PF00017	0.685
LIG_SH2_STAT3	289	292	PF00017	0.679
LIG_SH2_STAT3	469	472	PF00017	0.693
LIG_SH2_STAT5	111	114	PF00017	0.750
LIG_SH2_STAT5	250	253	PF00017	0.389
LIG_SH2_STAT5	280	283	PF00017	0.599
LIG_SH2_STAT5	361	364	PF00017	0.479
LIG_SH2_STAT5	366	369	PF00017	0.451
LIG_SH2_STAT5	469	472	PF00017	0.591
LIG_SH3_1	119	125	PF00018	0.596
LIG_SH3_3	119	125	PF00018	0.694
LIG_SH3_3	191	197	PF00018	0.513
LIG_SH3_3	349	355	PF00018	0.681
LIG_SUMO_SIM_anti_2	596	603	PF11976	0.560
LIG_TRAF2_1	143	146	PF00917	0.520
LIG_TRAF2_1	51	54	PF00917	0.562
LIG_WRC_WIRS_1	223	228	PF05994	0.474
LIG_WRC_WIRS_1	63	68	PF05994	0.545
MOD_CDK_SPxK_1	94	100	PF00069	0.633
MOD_CDK_SPxxK_3	604	611	PF00069	0.600
MOD_CK1_1	105	111	PF00069	0.680
MOD_CK1_1	132	138	PF00069	0.660
MOD_CK1_1	157	163	PF00069	0.679
MOD_CK1_1	164	170	PF00069	0.660
MOD_CK1_1	346	352	PF00069	0.773
MOD_CK1_1	4	10	PF00069	0.582
MOD_CK1_1	404	410	PF00069	0.597
MOD_CK1_1	569	575	PF00069	0.724
MOD_CK1_1	577	583	PF00069	0.749
MOD_CK1_1	607	613	PF00069	0.692
MOD_CK1_1	65	71	PF00069	0.559
MOD_CK1_1	83	89	PF00069	0.745
MOD_CK1_1	94	100	PF00069	0.684
MOD_CK2_1	140	146	PF00069	0.502
MOD_CK2_1	212	218	PF00069	0.513
MOD_CK2_1	364	370	PF00069	0.536
MOD_CK2_1	48	54	PF00069	0.559
MOD_CK2_1	83	89	PF00069	0.721
MOD_Cter_Amidation	17	20	PF01082	0.506
MOD_Cter_Amidation	603	606	PF01082	0.614
MOD_GlcNHglycan	104	108	PF01048	0.716
MOD_GlcNHglycan	127	130	PF01048	0.750
MOD_GlcNHglycan	131	134	PF01048	0.791
MOD_GlcNHglycan	166	169	PF01048	0.722
MOD_GlcNHglycan	218	222	PF01048	0.391
MOD_GlcNHglycan	235	241	PF01048	0.300
MOD_GlcNHglycan	312	315	PF01048	0.576
MOD_GlcNHglycan	319	323	PF01048	0.590
MOD_GlcNHglycan	345	348	PF01048	0.781
MOD_GlcNHglycan	534	537	PF01048	0.756
MOD_GlcNHglycan	574	577	PF01048	0.712
MOD_GlcNHglycan	75	78	PF01048	0.689
MOD_GlcNHglycan	83	86	PF01048	0.650
MOD_GSK3_1	105	112	PF00069	0.733
MOD_GSK3_1	121	128	PF00069	0.588
MOD_GSK3_1	132	139	PF00069	0.536
MOD_GSK3_1	150	157	PF00069	0.525
MOD_GSK3_1	236	243	PF00069	0.693
MOD_GSK3_1	346	353	PF00069	0.738
MOD_GSK3_1	400	407	PF00069	0.647
MOD_GSK3_1	456	463	PF00069	0.682
MOD_GSK3_1	475	482	PF00069	0.455
MOD_GSK3_1	566	573	PF00069	0.763
MOD_GSK3_1	574	581	PF00069	0.599
MOD_GSK3_1	613	620	PF00069	0.654
MOD_GSK3_1	81	88	PF00069	0.794
MOD_LATS_1	550	556	PF00433	0.790
MOD_N-GLC_1	125	130	PF02516	0.708
MOD_NEK2_1	1	6	PF00069	0.760
MOD_NEK2_1	150	155	PF00069	0.626
MOD_NEK2_1	28	33	PF00069	0.581
MOD_NEK2_1	294	299	PF00069	0.549
MOD_NEK2_1	375	380	PF00069	0.580
MOD_NEK2_1	447	452	PF00069	0.706
MOD_NEK2_2	514	519	PF00069	0.596
MOD_PIKK_1	19	25	PF00454	0.523
MOD_PIKK_1	440	446	PF00454	0.674
MOD_PIKK_1	48	54	PF00454	0.661
MOD_PIKK_1	543	549	PF00454	0.657
MOD_PKA_1	19	25	PF00069	0.523
MOD_PKA_1	552	558	PF00069	0.801
MOD_PKA_2	19	25	PF00069	0.523
MOD_PKA_2	202	208	PF00069	0.436
MOD_PKA_2	552	558	PF00069	0.721
MOD_Plk_1	467	473	PF00069	0.698
MOD_Plk_1	514	520	PF00069	0.595
MOD_Plk_2-3	212	218	PF00069	0.513
MOD_Plk_2-3	364	370	PF00069	0.536
MOD_Plk_4	357	363	PF00069	0.640
MOD_Plk_4	404	410	PF00069	0.598
MOD_Plk_4	450	456	PF00069	0.660
MOD_ProDKin_1	121	127	PF00069	0.692
MOD_ProDKin_1	240	246	PF00069	0.563
MOD_ProDKin_1	312	318	PF00069	0.722
MOD_ProDKin_1	350	356	PF00069	0.741
MOD_ProDKin_1	457	463	PF00069	0.629
MOD_ProDKin_1	475	481	PF00069	0.466
MOD_ProDKin_1	604	610	PF00069	0.622
MOD_ProDKin_1	87	93	PF00069	0.753
MOD_ProDKin_1	94	100	PF00069	0.757
MOD_SUMO_for_1	522	525	PF00179	0.590
MOD_SUMO_rev_2	113	121	PF00179	0.591
MOD_SUMO_rev_2	141	150	PF00179	0.562
MOD_SUMO_rev_2	53	61	PF00179	0.651
TRG_DiLeu_BaEn_4	145	151	PF01217	0.494
TRG_DiLeu_BaLyEn_6	182	187	PF01217	0.513
TRG_DiLeu_BaLyEn_6	487	492	PF01217	0.530
TRG_ENDOCYTIC_2	111	114	PF00928	0.693
TRG_ENDOCYTIC_2	199	202	PF00928	0.411
TRG_ENDOCYTIC_2	250	253	PF00928	0.389
TRG_ENDOCYTIC_2	415	418	PF00928	0.530
TRG_ER_diArg_1	199	201	PF00400	0.398
TRG_ER_diArg_1	287	289	PF00400	0.563
TRG_ER_diArg_1	494	497	PF00400	0.628
TRG_ER_diArg_1	526	529	PF00400	0.655
TRG_ER_diArg_1	552	554	PF00400	0.641
TRG_ER_diArg_1	611	613	PF00400	0.650
TRG_NES_CRM1_1	292	305	PF08389	0.551
TRG_Pf-PMV_PEXEL_1	200	204	PF00026	0.418

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEJ9	Leptomonas seymouri	43%	100%
A0A3S7WRQ6	Leishmania donovani	99%	100%
A4H6L8	Leishmania braziliensis	72%	100%
E9ANN6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QGY7	Leishmania major	91%	100%