LeishMANIAdb
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Putative 40S ribosomal protein S21

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 40S ribosomal protein S21
Gene product:
40S ribosomal protein S21 - putative
Species:
Leishmania infantum
UniProt:
A4HUY7_LEIIN
TriTrypDb:
LINF_110013400 *
Length:
293

Annotations

Annotations by Jardim et al.

Ribosomal Protein, 40S ribosomal S21

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 2
GO:0043226 organelle 2 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A4HUY7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUY7

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 2
GO:0006518 peptide metabolic process 4 2
GO:0006807 nitrogen compound metabolic process 2 2
GO:0008152 metabolic process 1 2
GO:0009058 biosynthetic process 2 2
GO:0009059 macromolecule biosynthetic process 4 2
GO:0009987 cellular process 1 2
GO:0019538 protein metabolic process 3 2
GO:0034641 cellular nitrogen compound metabolic process 3 2
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 2
GO:0043043 peptide biosynthetic process 5 2
GO:0043170 macromolecule metabolic process 3 2
GO:0043603 amide metabolic process 3 2
GO:0043604 amide biosynthetic process 4 2
GO:0044237 cellular metabolic process 2 2
GO:0044238 primary metabolic process 2 2
GO:0044249 cellular biosynthetic process 3 2
GO:0044260 obsolete cellular macromolecule metabolic process 3 2
GO:0044271 cellular nitrogen compound biosynthetic process 4 2
GO:0071704 organic substance metabolic process 2 2
GO:1901564 organonitrogen compound metabolic process 3 2
GO:1901566 organonitrogen compound biosynthetic process 4 2
GO:1901576 organic substance biosynthetic process 3 2
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 2
GO:0005198 structural molecule activity 1 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 140 142 PF00675 0.224
CLV_NRD_NRD_1 22 24 PF00675 0.488
CLV_NRD_NRD_1 288 290 PF00675 0.522
CLV_PCSK_KEX2_1 212 214 PF00082 0.494
CLV_PCSK_PC1ET2_1 212 214 PF00082 0.494
CLV_PCSK_SKI1_1 3 7 PF00082 0.421
DEG_SCF_FBW7_1 35 42 PF00400 0.465
DOC_CDC14_PxL_1 57 65 PF14671 0.439
DOC_CDC14_PxL_1 95 103 PF14671 0.433
DOC_CKS1_1 36 41 PF01111 0.467
DOC_PP2B_LxvP_1 114 117 PF13499 0.431
DOC_PP2B_LxvP_1 137 140 PF13499 0.425
DOC_PP4_FxxP_1 58 61 PF00568 0.433
DOC_USP7_MATH_1 214 218 PF00917 0.512
DOC_USP7_MATH_1 45 49 PF00917 0.452
DOC_USP7_UBL2_3 212 216 PF12436 0.502
DOC_USP7_UBL2_3 221 225 PF12436 0.518
DOC_WW_Pin1_4 35 40 PF00397 0.473
DOC_WW_Pin1_4 46 51 PF00397 0.444
DOC_WW_Pin1_4 83 88 PF00397 0.447
LIG_14-3-3_CanoR_1 119 123 PF00244 0.451
LIG_14-3-3_CanoR_1 13 17 PF00244 0.454
LIG_14-3-3_CanoR_1 246 255 PF00244 0.532
LIG_14-3-3_CanoR_1 26 35 PF00244 0.481
LIG_APCC_ABBA_1 125 130 PF00400 0.224
LIG_BRCT_BRCA1_1 106 110 PF00533 0.433
LIG_BRCT_BRCA1_1 40 44 PF00533 0.459
LIG_BRCT_BRCA1_1 90 94 PF00533 0.452
LIG_FHA_1 144 150 PF00498 0.425
LIG_FHA_1 173 179 PF00498 0.425
LIG_FHA_1 98 104 PF00498 0.433
LIG_FHA_2 146 152 PF00498 0.425
LIG_FHA_2 75 81 PF00498 0.495
LIG_LIR_Gen_1 91 99 PF02991 0.440
LIG_LIR_Nem_3 86 92 PF02991 0.450
LIG_MLH1_MIPbox_1 40 44 PF16413 0.459
LIG_SH2_SRC 59 62 PF00017 0.428
LIG_SH2_STAT5 138 141 PF00017 0.425
LIG_SH2_STAT5 183 186 PF00017 0.425
LIG_SH2_STAT5 43 46 PF00017 0.468
LIG_SH2_STAT5 59 62 PF00017 0.428
LIG_SH2_STAT5 92 95 PF00017 0.450
LIG_SH3_4 221 228 PF00018 0.523
LIG_TYR_ITIM 90 95 PF00017 0.450
LIG_UBA3_1 203 210 PF00899 0.554
LIG_WW_3 116 120 PF00397 0.436
MOD_CDC14_SPxK_1 49 52 PF00782 0.433
MOD_CDK_SPxK_1 46 52 PF00069 0.443
MOD_CK1_1 105 111 PF00069 0.438
MOD_CK1_1 97 103 PF00069 0.432
MOD_CK2_1 145 151 PF00069 0.425
MOD_CK2_1 183 189 PF00069 0.425
MOD_CK2_1 27 33 PF00069 0.479
MOD_GlcNHglycan 104 107 PF01048 0.434
MOD_GSK3_1 105 112 PF00069 0.436
MOD_GSK3_1 183 190 PF00069 0.425
MOD_GSK3_1 212 219 PF00069 0.508
MOD_GSK3_1 35 42 PF00069 0.465
MOD_N-GLC_1 171 176 PF02516 0.224
MOD_N-GLC_1 71 76 PF02516 0.483
MOD_N-GLC_2 73 75 PF02516 0.488
MOD_NEK2_1 109 114 PF00069 0.446
MOD_NEK2_1 94 99 PF00069 0.434
MOD_NEK2_2 18 23 PF00069 0.478
MOD_NEK2_2 71 76 PF00069 0.483
MOD_PIKK_1 109 115 PF00454 0.444
MOD_PIKK_1 183 189 PF00454 0.425
MOD_PIKK_1 246 252 PF00454 0.535
MOD_PIKK_1 254 260 PF00454 0.531
MOD_PIKK_1 262 268 PF00454 0.531
MOD_PIKK_1 270 276 PF00454 0.529
MOD_PKA_1 212 218 PF00069 0.507
MOD_PKA_2 118 124 PF00069 0.441
MOD_PKA_2 12 18 PF00069 0.452
MOD_PKA_2 212 218 PF00069 0.507
MOD_PKA_2 237 243 PF00069 0.522
MOD_Plk_1 39 45 PF00069 0.461
MOD_Plk_4 105 111 PF00069 0.438
MOD_Plk_4 145 151 PF00069 0.425
MOD_Plk_4 3 9 PF00069 0.428
MOD_Plk_4 39 45 PF00069 0.461
MOD_ProDKin_1 35 41 PF00069 0.468
MOD_ProDKin_1 46 52 PF00069 0.443
MOD_ProDKin_1 83 89 PF00069 0.451
TRG_ENDOCYTIC_2 92 95 PF00928 0.450
TRG_NLS_MonoExtN_4 287 293 PF00514 0.527

Homologs

Protein Taxonomy Sequence identity Coverage
A0A1D8PCG7 CANAL 46% 100%
B3MLA8 DROAN 47% 100%
B3NA78 DROER 48% 100%
B4GSC0 DROPE 47% 100%
B4I2S0 DROSE 48% 100%
B4JZG4 DROGR 48% 100%
B4KIE3 DROMO 48% 100%
B4LQD3 DROVI 48% 100%
B4N002 DROWI 47% 100%
B4Q8M1 DROSI 47% 100%
O76927 DROME 48% 100%
O93798 NEUCR 42% 100%
P05764 SCHPO 52% 100%
P05765 RAT 46% 100%
P0C0V8 YEAST 46% 100%
P35687 ORYSJ 52% 100%
P49197 CAEEL 41% 100%
P63220 HUMAN 46% 100%
P63221 PIG 46% 100%
Q29KF5 DROPS 47% 100%
Q32PB8 BOVIN 46% 100%
Q3E754 YEAST 46% 100%
Q3E902 ARATH 46% 100%
Q41852 MAIZE 49% 100%
Q4GXP2 BIPLU 44% 100%
Q4GXP3 AGRLI 47% 100%
Q4KTC0 SUBDO 46% 100%
Q4PM64 IXOSC 48% 100%
Q4WI01 ASPFU 51% 100%
Q54BN4 DICDI 47% 100%
Q612Q9 CAEBR 44% 100%
Q6AZJ9 XENLA 47% 100%
Q6CXT6 KLULA 44% 100%
Q6DDC6 XENTR 51% 100%
Q6F477 PLUXY 47% 100%
Q6FMF8 CANGA 46% 100%
Q6PUF8 BOMMO 48% 100%
Q6RF66 PECGU 46% 100%
Q6XIR2 DROYA 48% 100%
Q75BL6 ASHGO 44% 100%
Q7ZUG5 DANRE 49% 100%
Q86CT3 BRABE 48% 100%
Q8I7N7 CERCA 44% 100%
Q90YQ2 ICTPU 49% 100%
Q962Q8 SPOFR 48% 100%
Q9CQR2 MOUSE 46% 100%
Q9M337 ARATH 42% 100%
Q9P844 CANAX 46% 100%
Q9SMI2 CYAPA 54% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS