LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein - conserved
Species:
Leishmania infantum
UniProt:
A4HUY3_LEIIN
TriTrypDb:
LINF_110013000
Length:
1267

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HUY3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUY3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1020 1024 PF00656 0.665
CLV_C14_Caspase3-7 240 244 PF00656 0.597
CLV_C14_Caspase3-7 345 349 PF00656 0.644
CLV_C14_Caspase3-7 44 48 PF00656 0.675
CLV_C14_Caspase3-7 54 58 PF00656 0.604
CLV_C14_Caspase3-7 672 676 PF00656 0.632
CLV_MEL_PAP_1 497 503 PF00089 0.639
CLV_NRD_NRD_1 1002 1004 PF00675 0.601
CLV_NRD_NRD_1 1204 1206 PF00675 0.615
CLV_NRD_NRD_1 134 136 PF00675 0.600
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IHG5 Leishmania donovani 99% 100%
A4H6J8 Leishmania braziliensis 58% 100%
E9ANL8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 99%
Q4QH05 Leishmania major 84% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS