LeishMANIAdb
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ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP-dependent DNA helicase
Gene product:
DNA repair and recombination helicase protein PIF2 - putative
Species:
Leishmania infantum
UniProt:
A4HUU3_LEIIN
TriTrypDb:
LINF_110008100 *
Length:
1515

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 6
GO:0110165 cellular anatomical entity 1 6
GO:0005657 replication fork 2 1

Expansion

Sequence features

A4HUU3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUU3

Function

Biological processes
Term Name Level Count
GO:0000723 telomere maintenance 5 6
GO:0006139 nucleobase-containing compound metabolic process 3 6
GO:0006259 DNA metabolic process 4 6
GO:0006281 DNA repair 5 6
GO:0006310 DNA recombination 5 6
GO:0006725 cellular aromatic compound metabolic process 3 6
GO:0006807 nitrogen compound metabolic process 2 6
GO:0006950 response to stress 2 6
GO:0006974 DNA damage response 4 6
GO:0006996 organelle organization 4 6
GO:0008152 metabolic process 1 6
GO:0009987 cellular process 1 6
GO:0016043 cellular component organization 3 6
GO:0032200 telomere organization 6 6
GO:0033554 cellular response to stress 3 6
GO:0034641 cellular nitrogen compound metabolic process 3 6
GO:0043170 macromolecule metabolic process 3 6
GO:0044237 cellular metabolic process 2 6
GO:0044238 primary metabolic process 2 6
GO:0044260 obsolete cellular macromolecule metabolic process 3 6
GO:0046483 heterocycle metabolic process 3 6
GO:0050896 response to stimulus 1 6
GO:0051276 chromosome organization 5 6
GO:0051716 cellular response to stimulus 2 6
GO:0071704 organic substance metabolic process 2 6
GO:0071840 cellular component organization or biogenesis 2 6
GO:0090304 nucleic acid metabolic process 4 6
GO:1901360 organic cyclic compound metabolic process 3 6
GO:0006260 DNA replication 5 1
GO:0032392 DNA geometric change 7 1
GO:0032508 DNA duplex unwinding 8 1
GO:0071103 DNA conformation change 6 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 6
GO:0003678 DNA helicase activity 3 6
GO:0003824 catalytic activity 1 6
GO:0004386 helicase activity 2 6
GO:0005488 binding 1 6
GO:0005524 ATP binding 5 6
GO:0008094 ATP-dependent activity, acting on DNA 2 6
GO:0016462 pyrophosphatase activity 5 6
GO:0016787 hydrolase activity 2 6
GO:0016817 hydrolase activity, acting on acid anhydrides 3 6
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 6
GO:0016887 ATP hydrolysis activity 7 6
GO:0017076 purine nucleotide binding 4 6
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 6
GO:0030554 adenyl nucleotide binding 5 6
GO:0032553 ribonucleotide binding 3 6
GO:0032555 purine ribonucleotide binding 4 6
GO:0032559 adenyl ribonucleotide binding 5 6
GO:0035639 purine ribonucleoside triphosphate binding 4 6
GO:0036094 small molecule binding 2 6
GO:0043167 ion binding 2 6
GO:0043168 anion binding 3 6
GO:0097159 organic cyclic compound binding 2 6
GO:0097367 carbohydrate derivative binding 2 6
GO:0140097 catalytic activity, acting on DNA 3 6
GO:0140640 catalytic activity, acting on a nucleic acid 2 6
GO:0140657 ATP-dependent activity 1 6
GO:1901265 nucleoside phosphate binding 3 6
GO:1901363 heterocyclic compound binding 2 6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1205 1209 PF00656 0.623
CLV_C14_Caspase3-7 153 157 PF00656 0.548
CLV_C14_Caspase3-7 372 376 PF00656 0.685
CLV_C14_Caspase3-7 582 586 PF00656 0.801
CLV_C14_Caspase3-7 96 100 PF00656 0.612
CLV_NRD_NRD_1 1028 1030 PF00675 0.716
CLV_NRD_NRD_1 1104 1106 PF00675 0.520
CLV_NRD_NRD_1 113 115 PF00675 0.571
CLV_NRD_NRD_1 1131 1133 PF00675 0.711
CLV_NRD_NRD_1 1274 1276 PF00675 0.568
CLV_NRD_NRD_1 1439 1441 PF00675 0.635
CLV_NRD_NRD_1 1444 1446 PF00675 0.614
CLV_NRD_NRD_1 1450 1452 PF00675 0.525
CLV_NRD_NRD_1 1496 1498 PF00675 0.678
CLV_NRD_NRD_1 1499 1501 PF00675 0.672
CLV_NRD_NRD_1 192 194 PF00675 0.606
CLV_NRD_NRD_1 232 234 PF00675 0.576
CLV_NRD_NRD_1 40 42 PF00675 0.586
CLV_NRD_NRD_1 509 511 PF00675 0.754
CLV_NRD_NRD_1 62 64 PF00675 0.573
CLV_NRD_NRD_1 629 631 PF00675 0.663
CLV_NRD_NRD_1 844 846 PF00675 0.528
CLV_NRD_NRD_1 875 877 PF00675 0.491
CLV_NRD_NRD_1 913 915 PF00675 0.574
CLV_NRD_NRD_1 941 943 PF00675 0.573
CLV_PCSK_FUR_1 1497 1501 PF00082 0.696
CLV_PCSK_KEX2_1 1027 1029 PF00082 0.728
CLV_PCSK_KEX2_1 1104 1106 PF00082 0.520
CLV_PCSK_KEX2_1 113 115 PF00082 0.571
CLV_PCSK_KEX2_1 1131 1133 PF00082 0.672
CLV_PCSK_KEX2_1 1439 1441 PF00082 0.635
CLV_PCSK_KEX2_1 1444 1446 PF00082 0.614
CLV_PCSK_KEX2_1 1452 1454 PF00082 0.488
CLV_PCSK_KEX2_1 1460 1462 PF00082 0.400
CLV_PCSK_KEX2_1 1498 1500 PF00082 0.701
CLV_PCSK_KEX2_1 192 194 PF00082 0.606
CLV_PCSK_KEX2_1 234 236 PF00082 0.577
CLV_PCSK_KEX2_1 382 384 PF00082 0.708
CLV_PCSK_KEX2_1 39 41 PF00082 0.604
CLV_PCSK_KEX2_1 523 525 PF00082 0.761
CLV_PCSK_KEX2_1 608 610 PF00082 0.743
CLV_PCSK_KEX2_1 62 64 PF00082 0.573
CLV_PCSK_KEX2_1 629 631 PF00082 0.663
CLV_PCSK_KEX2_1 844 846 PF00082 0.528
CLV_PCSK_KEX2_1 875 877 PF00082 0.491
CLV_PCSK_KEX2_1 913 915 PF00082 0.574
CLV_PCSK_KEX2_1 941 943 PF00082 0.573
CLV_PCSK_PC1ET2_1 1452 1454 PF00082 0.655
CLV_PCSK_PC1ET2_1 1460 1462 PF00082 0.540
CLV_PCSK_PC1ET2_1 1498 1500 PF00082 0.701
CLV_PCSK_PC1ET2_1 234 236 PF00082 0.559
CLV_PCSK_PC1ET2_1 382 384 PF00082 0.669
CLV_PCSK_PC1ET2_1 39 41 PF00082 0.547
CLV_PCSK_PC1ET2_1 523 525 PF00082 0.803
CLV_PCSK_PC1ET2_1 608 610 PF00082 0.743
CLV_PCSK_PC7_1 1440 1446 PF00082 0.675
CLV_PCSK_PC7_1 378 384 PF00082 0.712
CLV_PCSK_SKI1_1 1214 1218 PF00082 0.626
CLV_PCSK_SKI1_1 1252 1256 PF00082 0.553
CLV_PCSK_SKI1_1 1447 1451 PF00082 0.682
CLV_PCSK_SKI1_1 1484 1488 PF00082 0.651
CLV_PCSK_SKI1_1 239 243 PF00082 0.596
CLV_PCSK_SKI1_1 520 524 PF00082 0.807
CLV_PCSK_SKI1_1 630 634 PF00082 0.618
CLV_PCSK_SKI1_1 760 764 PF00082 0.714
CLV_PCSK_SKI1_1 794 798 PF00082 0.491
CLV_PCSK_SKI1_1 799 803 PF00082 0.418
CLV_PCSK_SKI1_1 864 868 PF00082 0.491
CLV_Separin_Metazoa 110 114 PF03568 0.563
DEG_SPOP_SBC_1 1137 1141 PF00917 0.695
DOC_CDC14_PxL_1 1065 1073 PF14671 0.479
DOC_CKS1_1 1237 1242 PF01111 0.613
DOC_CYCLIN_RxL_1 382 393 PF00134 0.695
DOC_CYCLIN_yClb5_NLxxxL_5 1254 1263 PF00134 0.588
DOC_CYCLIN_yClb5_NLxxxL_5 665 671 PF00134 0.599
DOC_CYCLIN_yCln2_LP_2 1071 1074 PF00134 0.588
DOC_CYCLIN_yCln2_LP_2 1241 1247 PF00134 0.512
DOC_MAPK_DCC_7 1087 1096 PF00069 0.564
DOC_MAPK_DCC_7 1163 1172 PF00069 0.578
DOC_MAPK_gen_1 1391 1400 PF00069 0.575
DOC_MAPK_gen_1 382 389 PF00069 0.712
DOC_MAPK_gen_1 39 50 PF00069 0.566
DOC_MAPK_gen_1 629 639 PF00069 0.561
DOC_MAPK_gen_1 722 729 PF00069 0.613
DOC_MAPK_gen_1 875 882 PF00069 0.413
DOC_MAPK_gen_1 913 921 PF00069 0.548
DOC_MAPK_gen_1 941 949 PF00069 0.552
DOC_MAPK_HePTP_8 872 884 PF00069 0.413
DOC_MAPK_JIP1_4 1243 1249 PF00069 0.567
DOC_MAPK_MEF2A_6 1087 1096 PF00069 0.564
DOC_MAPK_MEF2A_6 640 649 PF00069 0.589
DOC_MAPK_MEF2A_6 722 729 PF00069 0.617
DOC_MAPK_MEF2A_6 807 814 PF00069 0.433
DOC_MAPK_MEF2A_6 875 884 PF00069 0.413
DOC_MAPK_MEF2A_6 913 921 PF00069 0.548
DOC_MAPK_MEF2A_6 941 949 PF00069 0.552
DOC_MAPK_RevD_3 1092 1105 PF00069 0.544
DOC_PP1_RVXF_1 673 679 PF00149 0.559
DOC_PP1_RVXF_1 927 934 PF00149 0.529
DOC_PP1_RVXF_1 949 956 PF00149 0.603
DOC_PP2B_LxvP_1 1071 1074 PF13499 0.588
DOC_PP2B_LxvP_1 592 595 PF13499 0.621
DOC_PP2B_LxvP_1 604 607 PF13499 0.591
DOC_PP2B_LxvP_1 947 950 PF13499 0.521
DOC_PP2B_PxIxI_1 208 214 PF00149 0.580
DOC_PP4_FxxP_1 1309 1312 PF00568 0.573
DOC_USP7_MATH_1 1005 1009 PF00917 0.744
DOC_USP7_MATH_1 1136 1140 PF00917 0.743
DOC_USP7_MATH_1 1143 1147 PF00917 0.529
DOC_USP7_MATH_1 119 123 PF00917 0.538
DOC_USP7_MATH_1 149 153 PF00917 0.597
DOC_USP7_MATH_1 228 232 PF00917 0.609
DOC_USP7_MATH_1 252 256 PF00917 0.580
DOC_USP7_MATH_1 27 31 PF00917 0.510
DOC_USP7_MATH_1 369 373 PF00917 0.678
DOC_USP7_MATH_1 396 400 PF00917 0.709
DOC_USP7_MATH_1 478 482 PF00917 0.738
DOC_USP7_MATH_1 503 507 PF00917 0.719
DOC_USP7_MATH_1 529 533 PF00917 0.709
DOC_USP7_MATH_1 571 575 PF00917 0.833
DOC_USP7_MATH_1 616 620 PF00917 0.555
DOC_USP7_MATH_1 749 753 PF00917 0.736
DOC_USP7_MATH_1 86 90 PF00917 0.600
DOC_USP7_MATH_1 92 96 PF00917 0.583
DOC_USP7_MATH_2 703 709 PF00917 0.533
DOC_USP7_UBL2_3 1093 1097 PF12436 0.587
DOC_USP7_UBL2_3 5 9 PF12436 0.592
DOC_WW_Pin1_4 1015 1020 PF00397 0.787
DOC_WW_Pin1_4 1078 1083 PF00397 0.552
DOC_WW_Pin1_4 1236 1241 PF00397 0.611
DOC_WW_Pin1_4 1499 1504 PF00397 0.722
DOC_WW_Pin1_4 1509 1514 PF00397 0.681
DOC_WW_Pin1_4 274 279 PF00397 0.579
DOC_WW_Pin1_4 326 331 PF00397 0.773
DOC_WW_Pin1_4 736 741 PF00397 0.663
DOC_WW_Pin1_4 76 81 PF00397 0.626
DOC_WW_Pin1_4 834 839 PF00397 0.512
LIG_14-3-3_CanoR_1 1010 1019 PF00244 0.776
LIG_14-3-3_CanoR_1 1116 1121 PF00244 0.738
LIG_14-3-3_CanoR_1 126 135 PF00244 0.580
LIG_14-3-3_CanoR_1 1439 1443 PF00244 0.580
LIG_14-3-3_CanoR_1 1444 1450 PF00244 0.587
LIG_14-3-3_CanoR_1 1497 1503 PF00244 0.701
LIG_14-3-3_CanoR_1 233 243 PF00244 0.592
LIG_14-3-3_CanoR_1 436 444 PF00244 0.663
LIG_14-3-3_CanoR_1 542 549 PF00244 0.824
LIG_14-3-3_CanoR_1 57 65 PF00244 0.602
LIG_14-3-3_CanoR_1 675 679 PF00244 0.595
LIG_14-3-3_CanoR_1 693 700 PF00244 0.405
LIG_Actin_WH2_2 859 877 PF00022 0.491
LIG_APCC_ABBA_1 1216 1221 PF00400 0.639
LIG_APCC_ABBA_1 992 997 PF00400 0.748
LIG_BIR_III_2 363 367 PF00653 0.609
LIG_BRCT_BRCA1_1 1145 1149 PF00533 0.730
LIG_BRCT_BRCA1_1 891 895 PF00533 0.491
LIG_BRCT_BRCA1_1 908 912 PF00533 0.301
LIG_BRCT_BRCA1_1 951 955 PF00533 0.609
LIG_CSL_BTD_1 1079 1082 PF09270 0.527
LIG_CtBP_PxDLS_1 1073 1077 PF00389 0.591
LIG_CtBP_PxDLS_1 1350 1354 PF00389 0.524
LIG_FHA_1 1015 1021 PF00498 0.800
LIG_FHA_1 1052 1058 PF00498 0.615
LIG_FHA_1 1081 1087 PF00498 0.492
LIG_FHA_1 1096 1102 PF00498 0.374
LIG_FHA_1 116 122 PF00498 0.577
LIG_FHA_1 1328 1334 PF00498 0.573
LIG_FHA_1 208 214 PF00498 0.580
LIG_FHA_1 382 388 PF00498 0.613
LIG_FHA_1 418 424 PF00498 0.660
LIG_FHA_1 430 436 PF00498 0.653
LIG_FHA_1 496 502 PF00498 0.662
LIG_FHA_1 599 605 PF00498 0.639
LIG_FHA_1 626 632 PF00498 0.596
LIG_FHA_1 639 645 PF00498 0.422
LIG_FHA_1 651 657 PF00498 0.516
LIG_FHA_1 815 821 PF00498 0.491
LIG_FHA_1 906 912 PF00498 0.542
LIG_FHA_1 994 1000 PF00498 0.694
LIG_FHA_2 1043 1049 PF00498 0.620
LIG_FHA_2 1050 1056 PF00498 0.525
LIG_FHA_2 1223 1229 PF00498 0.611
LIG_FHA_2 198 204 PF00498 0.602
LIG_FHA_2 536 542 PF00498 0.772
LIG_FHA_2 657 663 PF00498 0.554
LIG_FHA_2 697 703 PF00498 0.540
LIG_FHA_2 732 738 PF00498 0.736
LIG_FHA_2 761 767 PF00498 0.648
LIG_Integrin_isoDGR_2 1320 1322 PF01839 0.635
LIG_Integrin_RGD_1 259 261 PF01839 0.601
LIG_IRF3_LxIS_1 830 837 PF10401 0.491
LIG_LIR_Apic_2 1306 1312 PF02991 0.581
LIG_LIR_Gen_1 500 509 PF02991 0.719
LIG_LIR_Gen_1 849 859 PF02991 0.499
LIG_LIR_Gen_1 865 874 PF02991 0.296
LIG_LIR_Gen_1 892 903 PF02991 0.491
LIG_LIR_Nem_3 1021 1026 PF02991 0.618
LIG_LIR_Nem_3 1192 1196 PF02991 0.458
LIG_LIR_Nem_3 1301 1305 PF02991 0.562
LIG_LIR_Nem_3 172 178 PF02991 0.582
LIG_LIR_Nem_3 214 220 PF02991 0.575
LIG_LIR_Nem_3 343 349 PF02991 0.739
LIG_LIR_Nem_3 500 505 PF02991 0.735
LIG_LIR_Nem_3 677 681 PF02991 0.637
LIG_LIR_Nem_3 849 854 PF02991 0.499
LIG_LIR_Nem_3 865 870 PF02991 0.296
LIG_LIR_Nem_3 892 898 PF02991 0.491
LIG_LYPXL_S_1 1167 1171 PF13949 0.571
LIG_MYND_1 1069 1073 PF01753 0.581
LIG_NRBOX 107 113 PF00104 0.569
LIG_PCNA_yPIPBox_3 1265 1276 PF02747 0.567
LIG_PCNA_yPIPBox_3 972 983 PF02747 0.684
LIG_Pex14_1 1080 1084 PF04695 0.562
LIG_Pex14_2 180 184 PF04695 0.589
LIG_Pex14_2 912 916 PF04695 0.553
LIG_PTB_Apo_2 1335 1342 PF02174 0.505
LIG_SH2_CRK 851 855 PF00017 0.499
LIG_SH2_NCK_1 502 506 PF00017 0.655
LIG_SH2_PTP2 175 178 PF00017 0.585
LIG_SH2_PTP2 25 28 PF00017 0.534
LIG_SH2_SRC 502 505 PF00017 0.657
LIG_SH2_STAP1 1299 1303 PF00017 0.541
LIG_SH2_STAP1 1355 1359 PF00017 0.532
LIG_SH2_STAP1 431 435 PF00017 0.699
LIG_SH2_STAP1 851 855 PF00017 0.499
LIG_SH2_STAT3 65 68 PF00017 0.570
LIG_SH2_STAT5 1084 1087 PF00017 0.517
LIG_SH2_STAT5 1106 1109 PF00017 0.552
LIG_SH2_STAT5 1111 1114 PF00017 0.589
LIG_SH2_STAT5 1196 1199 PF00017 0.577
LIG_SH2_STAT5 1285 1288 PF00017 0.599
LIG_SH2_STAT5 1302 1305 PF00017 0.307
LIG_SH2_STAT5 1386 1389 PF00017 0.535
LIG_SH2_STAT5 1457 1460 PF00017 0.588
LIG_SH2_STAT5 175 178 PF00017 0.585
LIG_SH2_STAT5 19 22 PF00017 0.548
LIG_SH2_STAT5 25 28 PF00017 0.511
LIG_SH2_STAT5 431 434 PF00017 0.641
LIG_SH2_STAT5 785 788 PF00017 0.491
LIG_SH3_3 1016 1022 PF00018 0.784
LIG_SH3_3 1163 1169 PF00018 0.567
LIG_SH3_3 1176 1182 PF00018 0.369
LIG_SH3_3 1309 1315 PF00018 0.555
LIG_SH3_3 1322 1328 PF00018 0.363
LIG_SH3_3 1389 1395 PF00018 0.559
LIG_SH3_3 29 35 PF00018 0.530
LIG_SH3_3 363 369 PF00018 0.745
LIG_SH3_3 574 580 PF00018 0.699
LIG_SH3_3 673 679 PF00018 0.617
LIG_SH3_3 697 703 PF00018 0.617
LIG_SUMO_SIM_anti_2 641 646 PF11976 0.594
LIG_SUMO_SIM_anti_2 852 858 PF11976 0.491
LIG_SUMO_SIM_par_1 209 214 PF11976 0.581
LIG_SUMO_SIM_par_1 242 247 PF11976 0.594
LIG_SUMO_SIM_par_1 758 766 PF11976 0.615
LIG_SUMO_SIM_par_1 852 858 PF11976 0.491
LIG_TRAF2_1 100 103 PF00917 0.599
LIG_TRAF2_1 140 143 PF00917 0.547
LIG_TRAF2_1 170 173 PF00917 0.586
LIG_TRAF2_1 331 334 PF00917 0.710
LIG_TRAF2_1 492 495 PF00917 0.738
LIG_UBA3_1 753 760 PF00899 0.708
LIG_UBA3_1 797 802 PF00899 0.491
LIG_WRC_WIRS_1 1064 1069 PF05994 0.517
LIG_WRC_WIRS_1 1096 1101 PF05994 0.558
LIG_WRC_WIRS_1 1400 1405 PF05994 0.595
MOD_CDK_SPK_2 76 81 PF00069 0.587
MOD_CDK_SPxK_1 1499 1505 PF00069 0.677
MOD_CDK_SPxxK_3 1236 1243 PF00069 0.608
MOD_CK1_1 1008 1014 PF00069 0.794
MOD_CK1_1 106 112 PF00069 0.530
MOD_CK1_1 1119 1125 PF00069 0.791
MOD_CK1_1 1139 1145 PF00069 0.713
MOD_CK1_1 1161 1167 PF00069 0.553
MOD_CK1_1 1267 1273 PF00069 0.558
MOD_CK1_1 1399 1405 PF00069 0.591
MOD_CK1_1 1467 1473 PF00069 0.639
MOD_CK1_1 237 243 PF00069 0.602
MOD_CK1_1 481 487 PF00069 0.752
MOD_CK1_1 638 644 PF00069 0.612
MOD_CK1_1 696 702 PF00069 0.548
MOD_CK1_1 736 742 PF00069 0.665
MOD_CK1_1 860 866 PF00069 0.491
MOD_CK1_1 984 990 PF00069 0.660
MOD_CK2_1 1042 1048 PF00069 0.615
MOD_CK2_1 1049 1055 PF00069 0.526
MOD_CK2_1 1156 1162 PF00069 0.692
MOD_CK2_1 137 143 PF00069 0.549
MOD_CK2_1 197 203 PF00069 0.572
MOD_CK2_1 28 34 PF00069 0.518
MOD_CK2_1 442 448 PF00069 0.754
MOD_CK2_1 489 495 PF00069 0.749
MOD_CK2_1 541 547 PF00069 0.742
MOD_CK2_1 656 662 PF00069 0.550
MOD_CK2_1 731 737 PF00069 0.775
MOD_CK2_1 749 755 PF00069 0.747
MOD_GlcNHglycan 1012 1015 PF01048 0.793
MOD_GlcNHglycan 1125 1128 PF01048 0.806
MOD_GlcNHglycan 1145 1148 PF01048 0.718
MOD_GlcNHglycan 121 124 PF01048 0.577
MOD_GlcNHglycan 128 131 PF01048 0.546
MOD_GlcNHglycan 138 142 PF01048 0.505
MOD_GlcNHglycan 1492 1495 PF01048 0.711
MOD_GlcNHglycan 152 155 PF01048 0.541
MOD_GlcNHglycan 166 169 PF01048 0.527
MOD_GlcNHglycan 296 299 PF01048 0.691
MOD_GlcNHglycan 322 326 PF01048 0.798
MOD_GlcNHglycan 425 428 PF01048 0.691
MOD_GlcNHglycan 456 459 PF01048 0.708
MOD_GlcNHglycan 478 481 PF01048 0.745
MOD_GlcNHglycan 573 576 PF01048 0.832
MOD_GlcNHglycan 618 621 PF01048 0.498
MOD_GlcNHglycan 707 710 PF01048 0.521
MOD_GlcNHglycan 73 76 PF01048 0.648
MOD_GlcNHglycan 740 743 PF01048 0.817
MOD_GlcNHglycan 891 894 PF01048 0.491
MOD_GSK3_1 1010 1017 PF00069 0.613
MOD_GSK3_1 1072 1079 PF00069 0.561
MOD_GSK3_1 1115 1122 PF00069 0.771
MOD_GSK3_1 1139 1146 PF00069 0.769
MOD_GSK3_1 115 122 PF00069 0.577
MOD_GSK3_1 1336 1343 PF00069 0.559
MOD_GSK3_1 1399 1406 PF00069 0.591
MOD_GSK3_1 1434 1441 PF00069 0.597
MOD_GSK3_1 233 240 PF00069 0.594
MOD_GSK3_1 745 752 PF00069 0.804
MOD_GSK3_1 981 988 PF00069 0.705
MOD_GSK3_1 995 1002 PF00069 0.630
MOD_LATS_1 1496 1502 PF00433 0.658
MOD_N-GLC_1 1147 1152 PF02516 0.651
MOD_N-GLC_1 1264 1269 PF02516 0.580
MOD_NEK2_1 1076 1081 PF00069 0.560
MOD_NEK2_1 115 120 PF00069 0.538
MOD_NEK2_1 1230 1235 PF00069 0.510
MOD_NEK2_1 1254 1259 PF00069 0.569
MOD_NEK2_1 137 142 PF00069 0.559
MOD_NEK2_1 1373 1378 PF00069 0.563
MOD_NEK2_1 1398 1403 PF00069 0.576
MOD_NEK2_1 1417 1422 PF00069 0.280
MOD_NEK2_1 155 160 PF00069 0.570
MOD_NEK2_1 164 169 PF00069 0.565
MOD_NEK2_1 408 413 PF00069 0.720
MOD_NEK2_1 476 481 PF00069 0.700
MOD_NEK2_1 713 718 PF00069 0.443
MOD_NEK2_1 906 911 PF00069 0.507
MOD_NEK2_2 1005 1010 PF00069 0.798
MOD_NEK2_2 1355 1360 PF00069 0.544
MOD_NEK2_2 228 233 PF00069 0.613
MOD_NEK2_2 530 535 PF00069 0.610
MOD_NEK2_2 635 640 PF00069 0.555
MOD_NEK2_2 826 831 PF00069 0.491
MOD_PIKK_1 1008 1014 PF00454 0.756
MOD_PIKK_1 1116 1122 PF00454 0.734
MOD_PIKK_1 1230 1236 PF00454 0.504
MOD_PIKK_1 1422 1428 PF00454 0.585
MOD_PIKK_1 478 484 PF00454 0.721
MOD_PIKK_1 64 70 PF00454 0.610
MOD_PIKK_1 820 826 PF00454 0.491
MOD_PK_1 1028 1034 PF00069 0.662
MOD_PK_1 1292 1298 PF00069 0.575
MOD_PKA_1 1028 1034 PF00069 0.662
MOD_PKA_1 1445 1451 PF00069 0.601
MOD_PKA_1 1498 1504 PF00069 0.709
MOD_PKA_1 233 239 PF00069 0.555
MOD_PKA_1 608 614 PF00069 0.661
MOD_PKA_2 1028 1034 PF00069 0.720
MOD_PKA_2 103 109 PF00069 0.580
MOD_PKA_2 1115 1121 PF00069 0.804
MOD_PKA_2 1123 1129 PF00069 0.686
MOD_PKA_2 1438 1444 PF00069 0.650
MOD_PKA_2 1490 1496 PF00069 0.710
MOD_PKA_2 1498 1504 PF00069 0.652
MOD_PKA_2 164 170 PF00069 0.569
MOD_PKA_2 228 234 PF00069 0.597
MOD_PKA_2 541 547 PF00069 0.849
MOD_PKA_2 56 62 PF00069 0.594
MOD_PKA_2 608 614 PF00069 0.661
MOD_PKA_2 650 656 PF00069 0.573
MOD_PKA_2 674 680 PF00069 0.568
MOD_PKA_2 705 711 PF00069 0.532
MOD_Plk_1 1005 1011 PF00069 0.798
MOD_Plk_1 1161 1167 PF00069 0.586
MOD_Plk_1 1228 1234 PF00069 0.605
MOD_Plk_1 1292 1298 PF00069 0.575
MOD_Plk_1 1373 1379 PF00069 0.569
MOD_Plk_1 1417 1423 PF00069 0.554
MOD_Plk_1 488 494 PF00069 0.754
MOD_Plk_1 696 702 PF00069 0.552
MOD_Plk_1 846 852 PF00069 0.497
MOD_Plk_1 857 863 PF00069 0.331
MOD_Plk_2-3 358 364 PF00069 0.712
MOD_Plk_2-3 489 495 PF00069 0.749
MOD_Plk_2-3 541 547 PF00069 0.713
MOD_Plk_2-3 559 565 PF00069 0.551
MOD_Plk_2-3 847 853 PF00069 0.491
MOD_Plk_4 103 109 PF00069 0.580
MOD_Plk_4 1072 1078 PF00069 0.595
MOD_Plk_4 1080 1086 PF00069 0.442
MOD_Plk_4 1267 1273 PF00069 0.558
MOD_Plk_4 1292 1298 PF00069 0.575
MOD_Plk_4 1363 1369 PF00069 0.592
MOD_Plk_4 1403 1409 PF00069 0.585
MOD_Plk_4 1445 1451 PF00069 0.624
MOD_Plk_4 28 34 PF00069 0.518
MOD_Plk_4 749 755 PF00069 0.751
MOD_Plk_4 781 787 PF00069 0.491
MOD_Plk_4 792 798 PF00069 0.199
MOD_Plk_4 857 863 PF00069 0.520
MOD_Plk_4 907 913 PF00069 0.514
MOD_ProDKin_1 1015 1021 PF00069 0.786
MOD_ProDKin_1 1078 1084 PF00069 0.546
MOD_ProDKin_1 1236 1242 PF00069 0.606
MOD_ProDKin_1 1499 1505 PF00069 0.726
MOD_ProDKin_1 1509 1515 PF00069 0.682
MOD_ProDKin_1 274 280 PF00069 0.579
MOD_ProDKin_1 326 332 PF00069 0.773
MOD_ProDKin_1 736 742 PF00069 0.665
MOD_ProDKin_1 76 82 PF00069 0.625
MOD_ProDKin_1 834 840 PF00069 0.512
MOD_SUMO_for_1 100 103 PF00179 0.599
MOD_SUMO_for_1 1303 1306 PF00179 0.513
MOD_SUMO_rev_2 1477 1486 PF00179 0.629
MOD_SUMO_rev_2 752 762 PF00179 0.775
TRG_DiLeu_BaEn_1 103 108 PF01217 0.580
TRG_DiLeu_BaEn_1 618 623 PF01217 0.599
TRG_DiLeu_BaEn_3 1188 1194 PF01217 0.567
TRG_DiLeu_BaEn_4 488 494 PF01217 0.696
TRG_DiLeu_BaLyEn_6 1476 1481 PF01217 0.559
TRG_DiLeu_BaLyEn_6 174 179 PF01217 0.581
TRG_DiLeu_BaLyEn_6 690 695 PF01217 0.587
TRG_DiLeu_BaLyEn_6 902 907 PF01217 0.582
TRG_ENDOCYTIC_2 1168 1171 PF00928 0.574
TRG_ENDOCYTIC_2 1386 1389 PF00928 0.535
TRG_ENDOCYTIC_2 175 178 PF00928 0.585
TRG_ENDOCYTIC_2 25 28 PF00928 0.534
TRG_ENDOCYTIC_2 346 349 PF00928 0.693
TRG_ENDOCYTIC_2 502 505 PF00928 0.657
TRG_ENDOCYTIC_2 624 627 PF00928 0.580
TRG_ENDOCYTIC_2 688 691 PF00928 0.616
TRG_ENDOCYTIC_2 851 854 PF00928 0.499
TRG_ER_diArg_1 1026 1029 PF00400 0.727
TRG_ER_diArg_1 1103 1105 PF00400 0.518
TRG_ER_diArg_1 112 114 PF00400 0.572
TRG_ER_diArg_1 1177 1180 PF00400 0.549
TRG_ER_diArg_1 1211 1214 PF00400 0.590
TRG_ER_diArg_1 1438 1440 PF00400 0.615
TRG_ER_diArg_1 1450 1453 PF00400 0.512
TRG_ER_diArg_1 1497 1500 PF00400 0.659
TRG_ER_diArg_1 232 235 PF00400 0.578
TRG_ER_diArg_1 40 43 PF00400 0.597
TRG_ER_diArg_1 435 438 PF00400 0.629
TRG_ER_diArg_1 62 64 PF00400 0.573
TRG_ER_diArg_1 629 631 PF00400 0.663
TRG_ER_diArg_1 874 876 PF00400 0.491
TRG_ER_diArg_1 912 914 PF00400 0.562
TRG_ER_diArg_1 940 942 PF00400 0.559
TRG_NES_CRM1_1 1363 1374 PF08389 0.572
TRG_NES_CRM1_1 292 304 PF08389 0.551
TRG_NLS_Bipartite_1 1444 1463 PF00514 0.624
TRG_NLS_Bipartite_1 510 527 PF00514 0.794
TRG_NLS_MonoCore_2 1496 1501 PF00514 0.653
TRG_NLS_MonoExtC_3 38 43 PF00514 0.538
TRG_NLS_MonoExtC_3 519 524 PF00514 0.807
TRG_NLS_MonoExtN_4 1444 1449 PF00514 0.678
TRG_NLS_MonoExtN_4 1497 1502 PF00514 0.700
TRG_NLS_MonoExtN_4 517 524 PF00514 0.808
TRG_Pf-PMV_PEXEL_1 113 117 PF00026 0.575
TRG_Pf-PMV_PEXEL_1 1275 1280 PF00026 0.520
TRG_Pf-PMV_PEXEL_1 1479 1483 PF00026 0.558
TRG_Pf-PMV_PEXEL_1 309 313 PF00026 0.783
TRG_Pf-PMV_PEXEL_1 385 390 PF00026 0.705
TRG_Pf-PMV_PEXEL_1 43 47 PF00026 0.562
TRG_Pf-PMV_PEXEL_1 665 670 PF00026 0.585
TRG_Pf-PMV_PEXEL_1 693 697 PF00026 0.606
TRG_Pf-PMV_PEXEL_1 799 803 PF00026 0.491
TRG_Pf-PMV_PEXEL_1 864 868 PF00026 0.491

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WRJ2 Leishmania donovani 99% 100%
A4H6E9 Leishmania braziliensis 80% 97%
E9ANH8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4QH48 Leishmania major 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS