Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Myotubularin-associated protein - putative

Species:

Leishmania infantum

UniProt:

A4HUS9_LEIIN

TriTrypDb:

LINF_110006600

Length:

717

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HUS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUS9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	249	253	PF00656	0.666
CLV_C14_Caspase3-7	538	542	PF00656	0.806
CLV_C14_Caspase3-7	565	569	PF00656	0.762
CLV_C14_Caspase3-7	605	609	PF00656	0.762
CLV_C14_Caspase3-7	64	68	PF00656	0.538
CLV_NRD_NRD_1	117	119	PF00675	0.283
CLV_NRD_NRD_1	318	320	PF00675	0.733
CLV_NRD_NRD_1	321	323	PF00675	0.703
CLV_NRD_NRD_1	546	548	PF00675	0.830
CLV_PCSK_KEX2_1	117	119	PF00082	0.435
CLV_PCSK_KEX2_1	155	157	PF00082	0.607
CLV_PCSK_KEX2_1	318	320	PF00082	0.733
CLV_PCSK_PC1ET2_1	155	157	PF00082	0.607
CLV_PCSK_SKI1_1	13	17	PF00082	0.435
CLV_PCSK_SKI1_1	133	137	PF00082	0.435
CLV_PCSK_SKI1_1	152	156	PF00082	0.361
CLV_PCSK_SKI1_1	219	223	PF00082	0.658
CLV_PCSK_SKI1_1	384	388	PF00082	0.672
CLV_PCSK_SKI1_1	423	427	PF00082	0.664
CLV_PCSK_SKI1_1	537	541	PF00082	0.767
CLV_Separin_Metazoa	381	385	PF03568	0.628
DEG_APCC_DBOX_1	143	151	PF00400	0.625
DEG_APCC_DBOX_1	696	704	PF00400	0.725
DEG_SCF_FBW7_1	557	564	PF00400	0.849
DEG_SCF_TRCP1_1	541	546	PF00400	0.676
DEG_SPOP_SBC_1	300	304	PF00917	0.639
DOC_CDC14_PxL_1	188	196	PF14671	0.693
DOC_CKS1_1	558	563	PF01111	0.851
DOC_CYCLIN_RxL_1	664	677	PF00134	0.771
DOC_CYCLIN_yClb5_NLxxxL_5	138	147	PF00134	0.622
DOC_CYCLIN_yCln2_LP_2	326	332	PF00134	0.718
DOC_MAPK_gen_1	131	138	PF00069	0.636
DOC_MAPK_MEF2A_6	36	44	PF00069	0.636
DOC_PP2B_LxvP_1	184	187	PF13499	0.640
DOC_PP2B_LxvP_1	194	197	PF13499	0.817
DOC_PP2B_LxvP_1	470	473	PF13499	0.761
DOC_PP4_FxxP_1	18	21	PF00568	0.636
DOC_USP7_MATH_1	187	191	PF00917	0.757
DOC_USP7_MATH_1	197	201	PF00917	0.746
DOC_USP7_MATH_1	270	274	PF00917	0.770
DOC_USP7_MATH_1	300	304	PF00917	0.716
DOC_USP7_MATH_1	346	350	PF00917	0.575
DOC_USP7_MATH_1	408	412	PF00917	0.672
DOC_USP7_MATH_1	471	475	PF00917	0.687
DOC_USP7_MATH_1	500	504	PF00917	0.808
DOC_USP7_MATH_1	539	543	PF00917	0.633
DOC_USP7_MATH_1	570	574	PF00917	0.685
DOC_USP7_MATH_1	601	605	PF00917	0.833
DOC_USP7_MATH_1	625	629	PF00917	0.739
DOC_USP7_MATH_1	636	640	PF00917	0.682
DOC_WW_Pin1_4	304	309	PF00397	0.841
DOC_WW_Pin1_4	342	347	PF00397	0.715
DOC_WW_Pin1_4	423	428	PF00397	0.778
DOC_WW_Pin1_4	448	453	PF00397	0.768
DOC_WW_Pin1_4	502	507	PF00397	0.863
DOC_WW_Pin1_4	511	516	PF00397	0.679
DOC_WW_Pin1_4	551	556	PF00397	0.806
DOC_WW_Pin1_4	557	562	PF00397	0.710
DOC_WW_Pin1_4	646	651	PF00397	0.804
LIG_14-3-3_CanoR_1	13	22	PF00244	0.636
LIG_14-3-3_CanoR_1	144	148	PF00244	0.608
LIG_14-3-3_CanoR_1	208	213	PF00244	0.723
LIG_14-3-3_CanoR_1	262	270	PF00244	0.836
LIG_14-3-3_CanoR_1	312	320	PF00244	0.773
LIG_14-3-3_CanoR_1	384	391	PF00244	0.676
LIG_14-3-3_CanoR_1	463	471	PF00244	0.811
LIG_14-3-3_CanoR_1	475	481	PF00244	0.637
LIG_14-3-3_CanoR_1	669	674	PF00244	0.852
LIG_Actin_WH2_2	131	146	PF00022	0.731
LIG_APCC_ABBAyCdc20_2	289	295	PF00400	0.617
LIG_BIR_II_1	1	5	PF00653	0.618
LIG_BIR_III_2	424	428	PF00653	0.707
LIG_BRCT_BRCA1_1	671	675	PF00533	0.774
LIG_Clathr_ClatBox_1	147	151	PF01394	0.529
LIG_Clathr_ClatBox_1	599	603	PF01394	0.830
LIG_DLG_GKlike_1	669	677	PF00625	0.772
LIG_EVH1_2	277	281	PF00568	0.714
LIG_EVH1_2	515	519	PF00568	0.740
LIG_FHA_1	138	144	PF00498	0.661
LIG_FHA_1	17	23	PF00498	0.580
LIG_FHA_1	239	245	PF00498	0.742
LIG_FHA_1	343	349	PF00498	0.705
LIG_FHA_1	359	365	PF00498	0.548
LIG_FHA_1	668	674	PF00498	0.784
LIG_FHA_2	312	318	PF00498	0.765
LIG_FHA_2	675	681	PF00498	0.769
LIG_GBD_Chelix_1	171	179	PF00786	0.618
LIG_GBD_Chelix_1	73	81	PF00786	0.352
LIG_LIR_Apic_2	16	21	PF02991	0.636
LIG_LIR_Gen_1	116	127	PF02991	0.626
LIG_LIR_Nem_3	116	122	PF02991	0.626
LIG_LIR_Nem_3	283	287	PF02991	0.558
LIG_LIR_Nem_3	354	360	PF02991	0.509
LIG_LIR_Nem_3	451	456	PF02991	0.601
LIG_LIR_Nem_3	628	634	PF02991	0.692
LIG_LYPXL_yS_3	631	634	PF13949	0.663
LIG_MYND_1	192	196	PF01753	0.736
LIG_NRBOX	699	705	PF00104	0.723
LIG_NRP_CendR_1	714	717	PF00754	0.791
LIG_Pex14_2	519	523	PF04695	0.734
LIG_SH2_SRC	290	293	PF00017	0.614
LIG_SH2_STAP1	371	375	PF00017	0.689
LIG_SH2_STAT3	419	422	PF00017	0.557
LIG_SH2_STAT5	14	17	PF00017	0.636
LIG_SH2_STAT5	290	293	PF00017	0.692
LIG_SH3_2	643	648	PF14604	0.845
LIG_SH3_3	189	195	PF00018	0.694
LIG_SH3_3	264	270	PF00018	0.805
LIG_SH3_3	27	33	PF00018	0.636
LIG_SH3_3	271	277	PF00018	0.734
LIG_SH3_3	330	336	PF00018	0.810
LIG_SH3_3	37	43	PF00018	0.518
LIG_SH3_3	431	437	PF00018	0.688
LIG_SH3_3	449	455	PF00018	0.592
LIG_SH3_3	503	509	PF00018	0.779
LIG_SH3_3	640	646	PF00018	0.817
LIG_SH3_3	653	659	PF00018	0.697
LIG_SH3_4	494	501	PF00018	0.745
LIG_SUMO_SIM_anti_2	596	601	PF11976	0.831
LIG_SUMO_SIM_par_1	134	140	PF11976	0.636
LIG_SUMO_SIM_par_1	454	460	PF11976	0.595
LIG_UBA3_1	147	155	PF00899	0.453
LIG_WRC_WIRS_1	353	358	PF05994	0.696
LIG_WRC_WIRS_1	520	525	PF05994	0.807
LIG_WW_1	642	645	PF00397	0.823
LIG_WW_3	195	199	PF00397	0.752
MOD_CDK_SPxxK_3	425	432	PF00069	0.769
MOD_CK1_1	137	143	PF00069	0.520
MOD_CK1_1	211	217	PF00069	0.754
MOD_CK1_1	240	246	PF00069	0.824
MOD_CK1_1	253	259	PF00069	0.688
MOD_CK1_1	299	305	PF00069	0.592
MOD_CK1_1	441	447	PF00069	0.745
MOD_CK1_1	451	457	PF00069	0.638
MOD_CK1_1	47	53	PF00069	0.617
MOD_CK1_1	510	516	PF00069	0.654
MOD_CK1_1	522	528	PF00069	0.635
MOD_CK1_1	582	588	PF00069	0.717
MOD_CK1_1	604	610	PF00069	0.816
MOD_CK1_1	611	617	PF00069	0.671
MOD_CK1_1	676	682	PF00069	0.779
MOD_CK1_1	686	692	PF00069	0.624
MOD_CK1_1	84	90	PF00069	0.636
MOD_CK2_1	28	34	PF00069	0.538
MOD_CK2_1	311	317	PF00069	0.765
MOD_CK2_1	55	61	PF00069	0.511
MOD_GlcNHglycan	107	110	PF01048	0.321
MOD_GlcNHglycan	189	192	PF01048	0.690
MOD_GlcNHglycan	203	206	PF01048	0.728
MOD_GlcNHglycan	210	213	PF01048	0.717
MOD_GlcNHglycan	255	258	PF01048	0.818
MOD_GlcNHglycan	298	301	PF01048	0.682
MOD_GlcNHglycan	412	415	PF01048	0.471
MOD_GlcNHglycan	440	443	PF01048	0.616
MOD_GlcNHglycan	464	467	PF01048	0.719
MOD_GlcNHglycan	478	481	PF01048	0.603
MOD_GlcNHglycan	49	52	PF01048	0.435
MOD_GlcNHglycan	502	505	PF01048	0.863
MOD_GlcNHglycan	525	528	PF01048	0.736
MOD_GlcNHglycan	541	544	PF01048	0.570
MOD_GlcNHglycan	572	575	PF01048	0.827
MOD_GlcNHglycan	610	613	PF01048	0.732
MOD_GlcNHglycan	639	642	PF01048	0.716
MOD_GlcNHglycan	665	668	PF01048	0.818
MOD_GSK3_1	197	204	PF00069	0.712
MOD_GSK3_1	219	226	PF00069	0.708
MOD_GSK3_1	238	245	PF00069	0.596
MOD_GSK3_1	246	253	PF00069	0.635
MOD_GSK3_1	295	302	PF00069	0.754
MOD_GSK3_1	342	349	PF00069	0.790
MOD_GSK3_1	358	365	PF00069	0.515
MOD_GSK3_1	404	411	PF00069	0.427
MOD_GSK3_1	471	478	PF00069	0.676
MOD_GSK3_1	490	497	PF00069	0.662
MOD_GSK3_1	507	514	PF00069	0.692
MOD_GSK3_1	515	522	PF00069	0.814
MOD_GSK3_1	539	546	PF00069	0.831
MOD_GSK3_1	557	564	PF00069	0.587
MOD_GSK3_1	570	577	PF00069	0.622
MOD_GSK3_1	602	609	PF00069	0.702
MOD_GSK3_1	610	617	PF00069	0.636
MOD_GSK3_1	663	670	PF00069	0.833
MOD_GSK3_1	679	686	PF00069	0.564
MOD_LATS_1	26	32	PF00433	0.636
MOD_N-GLC_1	490	495	PF02516	0.856
MOD_N-GLC_1	646	651	PF02516	0.770
MOD_N-GLC_1	667	672	PF02516	0.776
MOD_NEK2_1	1	6	PF00069	0.712
MOD_NEK2_1	143	148	PF00069	0.651
MOD_NEK2_1	150	155	PF00069	0.540
MOD_NEK2_1	44	49	PF00069	0.511
MOD_NEK2_1	457	462	PF00069	0.803
MOD_NEK2_1	519	524	PF00069	0.811
MOD_NEK2_1	530	535	PF00069	0.661
MOD_NEK2_1	602	607	PF00069	0.701
MOD_NEK2_1	673	678	PF00069	0.771
MOD_NEK2_1	693	698	PF00069	0.739
MOD_NEK2_1	81	86	PF00069	0.615
MOD_NEK2_2	55	60	PF00069	0.636
MOD_PIKK_1	197	203	PF00454	0.733
MOD_PIKK_1	384	390	PF00454	0.633
MOD_PIKK_1	494	500	PF00454	0.745
MOD_PIKK_1	611	617	PF00454	0.768
MOD_PIKK_1	687	693	PF00454	0.793
MOD_PIKK_1	84	90	PF00454	0.636
MOD_PK_1	28	34	PF00069	0.636
MOD_PKA_2	143	149	PF00069	0.665
MOD_PKA_2	197	203	PF00069	0.766
MOD_PKA_2	237	243	PF00069	0.766
MOD_PKA_2	296	302	PF00069	0.679
MOD_PKA_2	311	317	PF00069	0.682
MOD_PKA_2	462	468	PF00069	0.801
MOD_PKA_2	693	699	PF00069	0.692
MOD_Plk_1	150	156	PF00069	0.671
MOD_Plk_1	246	252	PF00069	0.812
MOD_Plk_1	55	61	PF00069	0.594
MOD_Plk_1	667	673	PF00069	0.775
MOD_Plk_4	1	7	PF00069	0.710
MOD_Plk_4	143	149	PF00069	0.567
MOD_Plk_4	219	225	PF00069	0.745
MOD_Plk_4	352	358	PF00069	0.697
MOD_Plk_4	44	50	PF00069	0.555
MOD_Plk_4	515	521	PF00069	0.800
MOD_ProDKin_1	304	310	PF00069	0.844
MOD_ProDKin_1	342	348	PF00069	0.706
MOD_ProDKin_1	423	429	PF00069	0.783
MOD_ProDKin_1	448	454	PF00069	0.768
MOD_ProDKin_1	502	508	PF00069	0.860
MOD_ProDKin_1	511	517	PF00069	0.678
MOD_ProDKin_1	551	557	PF00069	0.806
MOD_ProDKin_1	646	652	PF00069	0.804
MOD_SUMO_for_1	173	176	PF00179	0.654
MOD_SUMO_rev_2	316	324	PF00179	0.617
MOD_SUMO_rev_2	613	621	PF00179	0.665
TRG_ENDOCYTIC_2	119	122	PF00928	0.636
TRG_ENDOCYTIC_2	631	634	PF00928	0.760
TRG_ER_diArg_1	117	119	PF00400	0.483
TRG_ER_diArg_1	318	320	PF00400	0.656
TRG_NES_CRM1_1	69	82	PF08389	0.483
TRG_Pf-PMV_PEXEL_1	159	163	PF00026	0.616

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WRG7	Leishmania donovani	99%	100%
A4H9U1	Leishmania braziliensis	65%	98%
E9ANG3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QH63	Leishmania major	89%	100%