LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
cell cycle sequence binding phosphoprotein (RBP45) - putative
Species:
Leishmania infantum
UniProt:
A4HUS6_LEIIN
TriTrypDb:
LINF_110006300
Length:
292

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 14
NetGPI no yes: 0, no: 14
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HUS6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUS6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 185 189 PF00656 0.379
CLV_NRD_NRD_1 122 124 PF00675 0.581
CLV_NRD_NRD_1 150 152 PF00675 0.408
CLV_NRD_NRD_1 254 256 PF00675 0.267
CLV_PCSK_FUR_1 120 124 PF00082 0.662
CLV_PCSK_KEX2_1 120 122 PF00082 0.548
CLV_PCSK_KEX2_1 150 152 PF00082 0.353
CLV_PCSK_KEX2_1 254 256 PF00082 0.408
CLV_PCSK_PC1ET2_1 150 152 PF00082 0.353
CLV_PCSK_SKI1_1 152 156 PF00082 0.387
CLV_PCSK_SKI1_1 255 259 PF00082 0.287
DEG_SPOP_SBC_1 288 292 PF00917 0.395
DOC_CKS1_1 132 137 PF01111 0.527
DOC_CKS1_1 63 68 PF01111 0.506
DOC_MAPK_gen_1 204 214 PF00069 0.321
DOC_PP1_RVXF_1 253 260 PF00149 0.237
DOC_PP1_RVXF_1 264 270 PF00149 0.258
DOC_USP7_MATH_1 288 292 PF00917 0.425
DOC_USP7_UBL2_3 200 204 PF12436 0.426
DOC_WW_Pin1_4 131 136 PF00397 0.582
DOC_WW_Pin1_4 156 161 PF00397 0.378
DOC_WW_Pin1_4 62 67 PF00397 0.504
DOC_WW_Pin1_4 77 82 PF00397 0.587
LIG_14-3-3_CanoR_1 207 212 PF00244 0.269
LIG_14-3-3_CanoR_1 23 29 PF00244 0.417
LIG_14-3-3_CanoR_1 254 260 PF00244 0.286
LIG_FHA_1 2 8 PF00498 0.561
LIG_FHA_1 224 230 PF00498 0.400
LIG_FHA_1 35 41 PF00498 0.541
LIG_FHA_2 132 138 PF00498 0.678
LIG_FHA_2 183 189 PF00498 0.360
LIG_FHA_2 220 226 PF00498 0.295
LIG_LIR_Apic_2 159 165 PF02991 0.342
LIG_LIR_Gen_1 258 269 PF02991 0.463
LIG_LIR_Nem_3 268 272 PF02991 0.271
LIG_LIR_Nem_3 275 280 PF02991 0.266
LIG_PCNA_yPIPBox_3 15 23 PF02747 0.348
LIG_SH2_NCK_1 157 161 PF00017 0.358
LIG_SH2_PTP2 162 165 PF00017 0.337
LIG_SH2_STAP1 95 99 PF00017 0.508
LIG_SH2_STAT5 162 165 PF00017 0.337
LIG_SH2_STAT5 71 74 PF00017 0.692
LIG_SH3_3 108 114 PF00018 0.650
LIG_SH3_3 126 132 PF00018 0.689
LIG_SH3_3 48 54 PF00018 0.487
LIG_SUMO_SIM_par_1 210 215 PF11976 0.351
LIG_TRAF2_1 114 117 PF00917 0.585
LIG_TYR_ITIM 93 98 PF00017 0.508
LIG_WRC_WIRS_1 277 282 PF05994 0.246
LIG_WW_3 65 69 PF00397 0.673
MOD_CDK_SPxK_1 62 68 PF00069 0.517
MOD_CK2_1 131 137 PF00069 0.727
MOD_CK2_1 207 213 PF00069 0.265
MOD_CK2_1 219 225 PF00069 0.340
MOD_GlcNHglycan 238 241 PF01048 0.385
MOD_GlcNHglycan 56 59 PF01048 0.675
MOD_GlcNHglycan 77 80 PF01048 0.737
MOD_GSK3_1 101 108 PF00069 0.527
MOD_GSK3_1 219 226 PF00069 0.462
MOD_GSK3_1 82 89 PF00069 0.625
MOD_N-GLC_1 2 7 PF02516 0.595
MOD_N-GLC_1 75 80 PF02516 0.707
MOD_NEK2_1 1 6 PF00069 0.530
MOD_NEK2_1 212 217 PF00069 0.279
MOD_NEK2_1 276 281 PF00069 0.271
MOD_NEK2_1 29 34 PF00069 0.502
MOD_NEK2_2 260 265 PF00069 0.272
MOD_PIKK_1 212 218 PF00454 0.283
MOD_PK_1 207 213 PF00069 0.404
MOD_PKA_1 255 261 PF00069 0.280
MOD_PKA_2 22 28 PF00069 0.541
MOD_Plk_1 2 8 PF00069 0.590
MOD_Plk_1 212 218 PF00069 0.258
MOD_Plk_4 2 8 PF00069 0.540
MOD_Plk_4 207 213 PF00069 0.337
MOD_Plk_4 255 261 PF00069 0.298
MOD_ProDKin_1 131 137 PF00069 0.577
MOD_ProDKin_1 156 162 PF00069 0.382
MOD_ProDKin_1 62 68 PF00069 0.509
MOD_ProDKin_1 77 83 PF00069 0.589
TRG_DiLeu_BaEn_1 177 182 PF01217 0.328
TRG_ENDOCYTIC_2 261 264 PF00928 0.425
TRG_ENDOCYTIC_2 277 280 PF00928 0.156
TRG_ENDOCYTIC_2 95 98 PF00928 0.487
TRG_ER_diArg_1 120 123 PF00400 0.551
TRG_ER_diArg_1 151 154 PF00400 0.353
TRG_ER_diArg_1 280 283 PF00400 0.267
TRG_NES_CRM1_1 39 50 PF08389 0.461
TRG_NLS_MonoCore_2 149 154 PF00514 0.352
TRG_NLS_MonoExtN_4 150 155 PF00514 0.357
TRG_Pf-PMV_PEXEL_1 153 158 PF00026 0.346
TRG_Pf-PMV_PEXEL_1 270 275 PF00026 0.284
TRG_Pf-PMV_PEXEL_1 41 45 PF00026 0.553

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P8D9 Leptomonas seymouri 35% 100%
A0A0N1PAZ1 Leptomonas seymouri 84% 100%
A0A0S4JV55 Bodo saltans 50% 87%
A0A1X0NWX9 Trypanosomatidae 56% 97%
A0A3Q8I8Y8 Leishmania donovani 100% 100%
A0A3S5ISC8 Trypanosoma rangeli 52% 97%
A4H9U4 Leishmania braziliensis 92% 100%
A4HNG2 Leishmania braziliensis 27% 100%
D0A7N8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 49% 93%
E9ANG0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4QH66 Leishmania major 97% 100%
V5BB20 Trypanosoma cruzi 57% 97%
V5DLK4 Trypanosoma cruzi 51% 66%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2026 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS