DUF4291 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein - conserved

Species:

Leishmania infantum

UniProt:

A4HUM4_LEIIN

TriTrypDb:

LINF_100018500

Length:

139


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Could not find GO cellular_component term for this entry.

A4HUM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUM4

PDB structure(s): 7ane_aw


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.481
CLV_NRD_NRD_1	49	51	PF00675	0.365
CLV_NRD_NRD_1	98	100	PF00675	0.577
CLV_PCSK_KEX2_1	30	32	PF00082	0.378
CLV_PCSK_KEX2_1	98	100	PF00082	0.552
CLV_PCSK_PC1ET2_1	30	32	PF00082	0.467
CLV_PCSK_SKI1_1	27	31	PF00082	0.385
CLV_PCSK_SKI1_1	99	103	PF00082	0.503
DOC_MAPK_DCC_7	30	38	PF00069	0.368
DOC_MAPK_gen_1	127	135	PF00069	0.401
DOC_MAPK_gen_1	30	38	PF00069	0.410
DOC_MAPK_MEF2A_6	30	38	PF00069	0.368
LIG_deltaCOP1_diTrp_1	57	65	PF00928	0.402
LIG_FHA_1	9	15	PF00498	0.467
LIG_LIR_Gen_1	57	65	PF02991	0.445
LIG_LIR_Gen_1	78	87	PF02991	0.387
LIG_LIR_Gen_1	93	102	PF02991	0.388
LIG_LIR_Nem_3	57	61	PF02991	0.445
LIG_LIR_Nem_3	78	83	PF02991	0.417
LIG_LIR_Nem_3	93	97	PF02991	0.382
LIG_LYPXL_yS_3	122	125	PF13949	0.422
LIG_SH2_CRK	94	98	PF00017	0.442
LIG_SH2_GRB2like	94	97	PF00017	0.437
LIG_SH2_NCK_1	80	84	PF00017	0.404
LIG_SH2_STAT5	13	16	PF00017	0.376
LIG_SH2_STAT5	80	83	PF00017	0.460
LIG_SH3_3	117	123	PF00018	0.508
LIG_SH3_3	58	64	PF00018	0.400
MOD_GlcNHglycan	113	116	PF01048	0.586
MOD_NEK2_1	111	116	PF00069	0.504
MOD_NEK2_2	45	50	PF00069	0.353
TRG_ENDOCYTIC_2	122	125	PF00928	0.404
TRG_ENDOCYTIC_2	80	83	PF00928	0.403
TRG_ENDOCYTIC_2	94	97	PF00928	0.437
TRG_ER_diArg_1	97	99	PF00400	0.505
TRG_NES_CRM1_1	32	46	PF08389	0.479
TRG_NLS_MonoExtC_3	22	27	PF00514	0.508
TRG_NLS_MonoExtN_4	23	28	PF00514	0.507


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5W9	Leptomonas seymouri	79%	75%
A0A0S4IQ26	Bodo saltans	56%	68%
A0A1X0NQG0	Trypanosomatidae	70%	75%
A0A3Q8I8X2	Leishmania donovani	99%	100%
A0A422NGL2	Trypanosoma rangeli	69%	74%
A4H6A0	Leishmania braziliensis	90%	100%
C9ZVQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	76%
E9ANC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q4QHA2	Leishmania major	97%	100%