ABC1 domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ABC1 family - putative

Species:

Leishmania infantum

UniProt:

A4HUH2_LEIIN

TriTrypDb:

LINF_100012800

Length:

595

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

A4HUH2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUH2

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016740	transferase activity	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.235
CLV_C14_Caspase3-7	219	223	PF00656	0.226
CLV_NRD_NRD_1	15	17	PF00675	0.366
CLV_NRD_NRD_1	388	390	PF00675	0.518
CLV_NRD_NRD_1	514	516	PF00675	0.483
CLV_NRD_NRD_1	52	54	PF00675	0.558
CLV_NRD_NRD_1	584	586	PF00675	0.605
CLV_NRD_NRD_1	59	61	PF00675	0.493
CLV_NRD_NRD_1	8	10	PF00675	0.409
CLV_PCSK_KEX2_1	15	17	PF00082	0.366

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IC56	Leptomonas seymouri	29%	100%
A0A0N1PBZ9	Leptomonas seymouri	73%	100%
A0A0S4IL12	Bodo saltans	27%	100%
A0A0S4JQ43	Bodo saltans	48%	100%
A0A1X0NM90	Trypanosomatidae	29%	100%
A0A1X0NQ79	Trypanosomatidae	49%	83%
A0A3Q8IRU0	Leishmania donovani	29%	100%
A0A3R7M6H9	Trypanosoma rangeli	54%	88%
A0A3S7WR61	Leishmania donovani	100%	100%
A0A422NJA2	Trypanosoma rangeli	29%	100%

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