LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Amastin surface glycofamily protein

Quick info Annotations Function or PPIs Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Amastin surface glycofamily protein
Gene product:
Amastin surface glycoprotein - putative
Species:
Leishmania infantum
UniProt:
A4HUD2_LEIIN
TriTrypDb:
LINF_100007600
Length:
490

Annotations

Annotations by Jardim et al.

Plasma membrane, Amastin surface glyco

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 19
NetGPI no yes: 0, no: 19
Cellular components
Term Name Level Count
GO:0016020 membrane 2 16
GO:0110165 cellular anatomical entity 1 16

Phosphorylation

Promastigote: 93, 94

Expansion

Sequence features

A4HUD2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HUD2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 155 157 PF00675 0.515
CLV_NRD_NRD_1 344 346 PF00675 0.540
CLV_NRD_NRD_1 35 37 PF00675 0.487
CLV_NRD_NRD_1 52 54 PF00675 0.392
CLV_NRD_NRD_1 58 60 PF00675 0.427
CLV_NRD_NRD_1 76 78 PF00675 0.407
CLV_PCSK_FUR_1 74 78 PF00082 0.342
CLV_PCSK_KEX2_1 35 37 PF00082 0.494
CLV_PCSK_KEX2_1 65 67 PF00082 0.305
CLV_PCSK_KEX2_1 76 78 PF00082 0.405
CLV_PCSK_PC1ET2_1 65 67 PF00082 0.305
CLV_PCSK_SKI1_1 61 65 PF00082 0.388
DEG_MDM2_SWIB_1 284 292 PF02201 0.490
DOC_AGCK_PIF_1 225 230 PF00069 0.211
DOC_ANK_TNKS_1 113 120 PF00023 0.540
DOC_MAPK_gen_1 296 305 PF00069 0.444
DOC_MAPK_gen_1 366 375 PF00069 0.326
DOC_MAPK_MEF2A_6 298 307 PF00069 0.444
DOC_MAPK_MEF2A_6 394 402 PF00069 0.544
DOC_MAPK_RevD_3 333 346 PF00069 0.228
DOC_PP1_RVXF_1 296 303 PF00149 0.444
DOC_USP7_MATH_1 190 194 PF00917 0.270
DOC_USP7_MATH_1 333 337 PF00917 0.232
DOC_USP7_MATH_1 5 9 PF00917 0.615
DOC_USP7_UBL2_3 61 65 PF12436 0.704
DOC_WW_Pin1_4 429 434 PF00397 0.266
LIG_14-3-3_CanoR_1 24 28 PF00244 0.651
LIG_14-3-3_CanoR_1 348 353 PF00244 0.413
LIG_14-3-3_CanoR_1 4 14 PF00244 0.635
LIG_BIR_II_1 1 5 PF00653 0.680
LIG_BRCT_BRCA1_1 226 230 PF00533 0.275
LIG_BRCT_BRCA1_1 400 404 PF00533 0.364
LIG_BRCT_BRCA1_1 407 411 PF00533 0.372
LIG_FHA_1 20 26 PF00498 0.596
LIG_FHA_1 287 293 PF00498 0.583
LIG_FHA_1 295 301 PF00498 0.560
LIG_FHA_1 309 315 PF00498 0.295
LIG_FHA_1 412 418 PF00498 0.375
LIG_FHA_1 476 482 PF00498 0.310
LIG_FHA_2 113 119 PF00498 0.575
LIG_FHA_2 28 34 PF00498 0.688
LIG_Integrin_isoDGR_2 424 426 PF01839 0.409
LIG_LIR_Gen_1 197 205 PF02991 0.439
LIG_LIR_Gen_1 227 238 PF02991 0.339
LIG_LIR_Gen_1 377 387 PF02991 0.326
LIG_LIR_Gen_1 395 404 PF02991 0.589
LIG_LIR_Gen_1 414 421 PF02991 0.405
LIG_LIR_Gen_1 437 447 PF02991 0.306
LIG_LIR_LC3C_4 234 239 PF02991 0.357
LIG_LIR_Nem_3 197 201 PF02991 0.398
LIG_LIR_Nem_3 224 228 PF02991 0.340
LIG_LIR_Nem_3 229 233 PF02991 0.360
LIG_LIR_Nem_3 234 238 PF02991 0.390
LIG_LIR_Nem_3 377 383 PF02991 0.326
LIG_LIR_Nem_3 395 400 PF02991 0.520
LIG_LIR_Nem_3 414 419 PF02991 0.329
LIG_LIR_Nem_3 441 447 PF02991 0.302
LIG_LIR_Nem_3 465 470 PF02991 0.286
LIG_PAM2_1 130 142 PF00658 0.261
LIG_Pex14_1 324 328 PF04695 0.287
LIG_Pex14_2 137 141 PF04695 0.419
LIG_Pex14_2 221 225 PF04695 0.298
LIG_Pex14_2 284 288 PF04695 0.477
LIG_SH2_CRK 129 133 PF00017 0.357
LIG_SH2_CRK 358 362 PF00017 0.280
LIG_SH2_CRK 444 448 PF00017 0.357
LIG_SH2_PTP2 304 307 PF00017 0.270
LIG_SH2_PTP2 397 400 PF00017 0.516
LIG_SH2_STAP1 181 185 PF00017 0.227
LIG_SH2_STAP1 226 230 PF00017 0.248
LIG_SH2_STAP1 406 410 PF00017 0.441
LIG_SH2_STAT3 181 184 PF00017 0.244
LIG_SH2_STAT3 393 396 PF00017 0.436
LIG_SH2_STAT5 129 132 PF00017 0.357
LIG_SH2_STAT5 304 307 PF00017 0.298
LIG_SH2_STAT5 321 324 PF00017 0.219
LIG_SH2_STAT5 397 400 PF00017 0.542
LIG_Sin3_2 367 376 PF02671 0.201
LIG_SUMO_SIM_anti_2 477 483 PF11976 0.354
LIG_SUMO_SIM_par_1 39 46 PF11976 0.606
LIG_SUMO_SIM_par_1 417 422 PF11976 0.379
LIG_TRAF2_1 15 18 PF00917 0.743
LIG_TYR_ITIM 127 132 PF00017 0.357
LIG_WRC_WIRS_1 195 200 PF05994 0.315
LIG_WRC_WIRS_1 222 227 PF05994 0.357
LIG_WRC_WIRS_1 242 247 PF05994 0.178
LIG_WRC_WIRS_1 349 354 PF05994 0.306
MOD_CK1_1 224 230 PF00069 0.403
MOD_CK1_1 231 237 PF00069 0.322
MOD_CK1_1 291 297 PF00069 0.607
MOD_CK1_1 434 440 PF00069 0.230
MOD_CK1_1 459 465 PF00069 0.235
MOD_CK2_1 112 118 PF00069 0.696
MOD_CK2_1 459 465 PF00069 0.304
MOD_CK2_1 49 55 PF00069 0.595
MOD_CK2_1 91 97 PF00069 0.770
MOD_Cter_Amidation 154 157 PF01082 0.498
MOD_GlcNHglycan 132 135 PF01048 0.248
MOD_GlcNHglycan 153 156 PF01048 0.619
MOD_GlcNHglycan 205 208 PF01048 0.363
MOD_GlcNHglycan 25 28 PF01048 0.500
MOD_GlcNHglycan 293 296 PF01048 0.429
MOD_GlcNHglycan 433 436 PF01048 0.535
MOD_GlcNHglycan 448 451 PF01048 0.575
MOD_GlcNHglycan 458 461 PF01048 0.534
MOD_GSK3_1 108 115 PF00069 0.710
MOD_GSK3_1 19 26 PF00069 0.712
MOD_GSK3_1 190 197 PF00069 0.320
MOD_GSK3_1 217 224 PF00069 0.468
MOD_GSK3_1 344 351 PF00069 0.297
MOD_GSK3_1 411 418 PF00069 0.382
MOD_GSK3_1 431 438 PF00069 0.377
MOD_LATS_1 47 53 PF00433 0.528
MOD_N-GLC_1 456 461 PF02516 0.421
MOD_NEK2_1 139 144 PF00069 0.350
MOD_NEK2_1 217 222 PF00069 0.466
MOD_NEK2_1 228 233 PF00069 0.305
MOD_NEK2_1 241 246 PF00069 0.289
MOD_NEK2_1 313 318 PF00069 0.415
MOD_NEK2_1 374 379 PF00069 0.392
MOD_NEK2_1 411 416 PF00069 0.467
MOD_NEK2_1 419 424 PF00069 0.500
MOD_NEK2_2 308 313 PF00069 0.238
MOD_PIKK_1 112 118 PF00454 0.576
MOD_PIKK_1 392 398 PF00454 0.428
MOD_PKA_2 161 167 PF00069 0.314
MOD_PKA_2 23 29 PF00069 0.646
MOD_PKA_2 344 350 PF00069 0.326
MOD_PKA_2 5 11 PF00069 0.613
MOD_Plk_1 177 183 PF00069 0.251
MOD_Plk_1 331 337 PF00069 0.316
MOD_Plk_1 47 53 PF00069 0.610
MOD_Plk_4 190 196 PF00069 0.343
MOD_Plk_4 217 223 PF00069 0.452
MOD_Plk_4 263 269 PF00069 0.326
MOD_Plk_4 275 281 PF00069 0.280
MOD_Plk_4 308 314 PF00069 0.385
MOD_Plk_4 319 325 PF00069 0.310
MOD_Plk_4 333 339 PF00069 0.257
MOD_Plk_4 348 354 PF00069 0.377
MOD_Plk_4 374 380 PF00069 0.353
MOD_Plk_4 482 488 PF00069 0.330
MOD_ProDKin_1 429 435 PF00069 0.266
TRG_DiLeu_BaEn_1 465 470 PF01217 0.357
TRG_ENDOCYTIC_2 129 132 PF00928 0.357
TRG_ENDOCYTIC_2 242 245 PF00928 0.383
TRG_ENDOCYTIC_2 304 307 PF00928 0.419
TRG_ENDOCYTIC_2 397 400 PF00928 0.454
TRG_ENDOCYTIC_2 444 447 PF00928 0.306
TRG_ER_diArg_1 3 6 PF00400 0.623
TRG_ER_diArg_1 34 36 PF00400 0.676

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6X2 Leptomonas seymouri 63% 97%
A0A0N1PC74 Leptomonas seymouri 26% 97%
A0A0N1PCA2 Leptomonas seymouri 28% 100%
A0A0S4IH58 Bodo saltans 22% 83%
A0A3Q8I8Q6 Leishmania donovani 100% 100%
A0A3S7WR28 Leishmania donovani 27% 100%
A0A3S7X1E1 Leishmania donovani 28% 94%
A4H605 Leishmania braziliensis 71% 100%
A4H606 Leishmania braziliensis 25% 99%
A4HGF8 Leishmania braziliensis 29% 100%
A4HUD3 Leishmania infantum 27% 100%
A4I3I9 Leishmania infantum 28% 94%
E9AN32 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
E9AN33 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AZT1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
Q4Q8F3 Leishmania major 27% 100%
Q4QHJ3 Leishmania major 28% 97%
Q4QHJ4 Leishmania major 92% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS