DUF202 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

catalytic subunit of the vacuolar transporter chaperone 4 - putative

Species:

Leishmania infantum

UniProt:

A4HTV2_LEIIN

TriTrypDb:

LINF_090007800 , LINF_090009700

Length:

593

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HTV2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	111	115	PF00656	0.525
CLV_C14_Caspase3-7	307	311	PF00656	0.557
CLV_C14_Caspase3-7	588	592	PF00656	0.245
CLV_NRD_NRD_1	219	221	PF00675	0.633
CLV_NRD_NRD_1	298	300	PF00675	0.586
CLV_NRD_NRD_1	409	411	PF00675	0.374
CLV_NRD_NRD_1	544	546	PF00675	0.227
CLV_NRD_NRD_1	549	551	PF00675	0.251
CLV_NRD_NRD_1	581	583	PF00675	0.234
CLV_NRD_NRD_1	87	89	PF00675	0.469
CLV_PCSK_FUR_1	542	546	PF00082	0.214
CLV_PCSK_KEX2_1	219	221	PF00082	0.633
CLV_PCSK_KEX2_1	281	283	PF00082	0.565
CLV_PCSK_KEX2_1	297	299	PF00082	0.491
CLV_PCSK_KEX2_1	385	387	PF00082	0.488
CLV_PCSK_KEX2_1	409	411	PF00082	0.343
CLV_PCSK_KEX2_1	455	457	PF00082	0.441
CLV_PCSK_KEX2_1	544	546	PF00082	0.227
CLV_PCSK_KEX2_1	549	551	PF00082	0.251
CLV_PCSK_KEX2_1	581	583	PF00082	0.234
CLV_PCSK_KEX2_1	87	89	PF00082	0.469
CLV_PCSK_PC1ET2_1	281	283	PF00082	0.594
CLV_PCSK_PC1ET2_1	297	299	PF00082	0.491
CLV_PCSK_PC1ET2_1	385	387	PF00082	0.476
CLV_PCSK_PC1ET2_1	455	457	PF00082	0.441
CLV_PCSK_PC7_1	545	551	PF00082	0.244
CLV_PCSK_SKI1_1	173	177	PF00082	0.375
CLV_PCSK_SKI1_1	248	252	PF00082	0.488
CLV_PCSK_SKI1_1	345	349	PF00082	0.614
CLV_PCSK_SKI1_1	455	459	PF00082	0.319
CLV_PCSK_SKI1_1	466	470	PF00082	0.205
CLV_PCSK_SKI1_1	497	501	PF00082	0.214
CLV_PCSK_SKI1_1	72	76	PF00082	0.430
CLV_PCSK_SKI1_1	90	94	PF00082	0.317
DEG_APCC_DBOX_1	247	255	PF00400	0.441
DEG_SPOP_SBC_1	35	39	PF00917	0.523
DEG_SPOP_SBC_1	365	369	PF00917	0.357
DEG_SPOP_SBC_1	47	51	PF00917	0.523
DOC_CYCLIN_RxL_1	494	504	PF00134	0.214
DOC_CYCLIN_RxL_1	69	78	PF00134	0.435
DOC_CYCLIN_RxL_1	87	95	PF00134	0.312
DOC_MAPK_gen_1	130	139	PF00069	0.518
DOC_MAPK_gen_1	245	253	PF00069	0.488
DOC_MAPK_MEF2A_6	173	180	PF00069	0.372
DOC_MAPK_MEF2A_6	245	253	PF00069	0.488
DOC_MAPK_RevD_3	74	88	PF00069	0.449
DOC_PP2B_LxvP_1	499	502	PF13499	0.214
DOC_PP4_FxxP_1	57	60	PF00568	0.495
DOC_USP7_MATH_1	117	121	PF00917	0.601
DOC_USP7_MATH_1	125	129	PF00917	0.464
DOC_USP7_MATH_1	148	152	PF00917	0.546
DOC_USP7_MATH_1	34	38	PF00917	0.527
DOC_USP7_MATH_1	356	360	PF00917	0.429
DOC_USP7_MATH_1	434	438	PF00917	0.421
DOC_USP7_MATH_1	47	51	PF00917	0.498
DOC_USP7_MATH_1	53	57	PF00917	0.363
DOC_USP7_UBL2_3	458	462	PF12436	0.338
DOC_WW_Pin1_4	40	45	PF00397	0.557
DOC_WW_Pin1_4	506	511	PF00397	0.214
LIG_14-3-3_CanoR_1	116	122	PF00244	0.615
LIG_14-3-3_CanoR_1	219	224	PF00244	0.621
LIG_APCC_ABBA_1	419	424	PF00400	0.302
LIG_BIR_III_2	114	118	PF00653	0.506
LIG_BRCT_BRCA1_1	491	495	PF00533	0.214
LIG_BRCT_BRCA1_1	589	593	PF00533	0.244
LIG_BRCT_BRCA1_2	491	497	PF00533	0.214
LIG_eIF4E_1	463	469	PF01652	0.297
LIG_FHA_1	258	264	PF00498	0.481
LIG_FHA_1	268	274	PF00498	0.456
LIG_FHA_1	414	420	PF00498	0.311
LIG_FHA_1	425	431	PF00498	0.341
LIG_FHA_1	518	524	PF00498	0.242
LIG_FHA_1	53	59	PF00498	0.473
LIG_FHA_1	562	568	PF00498	0.230
LIG_FHA_2	196	202	PF00498	0.469
LIG_FHA_2	210	216	PF00498	0.438
LIG_FHA_2	371	377	PF00498	0.345
LIG_FHA_2	586	592	PF00498	0.244
LIG_Integrin_RGD_1	15	17	PF01839	0.422
LIG_LIR_Apic_2	55	60	PF02991	0.500
LIG_LIR_Gen_1	369	379	PF02991	0.347
LIG_LIR_Gen_1	514	524	PF02991	0.214
LIG_LIR_Gen_1	531	541	PF02991	0.202
LIG_LIR_Gen_1	561	569	PF02991	0.216
LIG_LIR_Gen_1	570	579	PF02991	0.211
LIG_LIR_Nem_3	369	375	PF02991	0.337
LIG_LIR_Nem_3	415	420	PF02991	0.362
LIG_LIR_Nem_3	483	488	PF02991	0.214
LIG_LIR_Nem_3	514	519	PF02991	0.214
LIG_LIR_Nem_3	531	537	PF02991	0.202
LIG_LIR_Nem_3	561	565	PF02991	0.217
LIG_LIR_Nem_3	570	574	PF02991	0.209
LIG_MAD2	135	143	PF02301	0.538
LIG_MYND_1	397	401	PF01753	0.334
LIG_NRBOX	343	349	PF00104	0.577
LIG_PDZ_Class_3	588	593	PF00595	0.244
LIG_Pex14_1	512	516	PF04695	0.227
LIG_Pex14_1	562	566	PF04695	0.216
LIG_PTAP_UEV_1	43	48	PF05743	0.574
LIG_RPA_C_Fungi	540	552	PF08784	0.236
LIG_RPA_C_Plants	248	259	PF08784	0.427
LIG_SH2_CRK	446	450	PF00017	0.433
LIG_SH2_CRK	534	538	PF00017	0.325
LIG_SH2_SRC	534	537	PF00017	0.214
LIG_SH2_SRC	554	557	PF00017	0.212
LIG_SH2_STAP1	554	558	PF00017	0.224
LIG_SH2_STAT5	179	182	PF00017	0.418
LIG_SH2_STAT5	315	318	PF00017	0.494
LIG_SH2_STAT5	414	417	PF00017	0.306
LIG_SH2_STAT5	536	539	PF00017	0.332
LIG_SH2_STAT5	98	101	PF00017	0.478
LIG_SH3_3	137	143	PF00018	0.540
LIG_SH3_3	41	47	PF00018	0.576
LIG_SH3_3	554	560	PF00018	0.222
LIG_SH3_3	79	85	PF00018	0.449
LIG_Sin3_3	526	533	PF02671	0.214
LIG_TRFH_1	417	421	PF08558	0.315
LIG_TYR_ITIM	444	449	PF00017	0.293
LIG_TYR_ITIM	532	537	PF00017	0.214
LIG_TYR_ITIM	552	557	PF00017	0.219
LIG_WRC_WIRS_1	414	419	PF05994	0.311
MOD_CK1_1	208	214	PF00069	0.571
MOD_CK1_1	233	239	PF00069	0.485
MOD_CK1_1	64	70	PF00069	0.394
MOD_CK2_1	195	201	PF00069	0.467
MOD_CK2_1	209	215	PF00069	0.437
MOD_CK2_1	301	307	PF00069	0.551
MOD_Cter_Amidation	453	456	PF01082	0.295
MOD_GlcNHglycan	154	157	PF01048	0.531
MOD_GlcNHglycan	189	192	PF01048	0.457
MOD_GlcNHglycan	207	210	PF01048	0.405
MOD_GlcNHglycan	232	235	PF01048	0.556
MOD_GlcNHglycan	277	280	PF01048	0.572
MOD_GlcNHglycan	357	361	PF01048	0.454
MOD_GlcNHglycan	38	41	PF01048	0.546
MOD_GlcNHglycan	50	53	PF01048	0.455
MOD_GSK3_1	148	155	PF00069	0.528
MOD_GSK3_1	205	212	PF00069	0.565
MOD_GSK3_1	215	222	PF00069	0.518
MOD_GSK3_1	236	243	PF00069	0.409
MOD_GSK3_1	297	304	PF00069	0.578
MOD_GSK3_1	30	37	PF00069	0.505
MOD_GSK3_1	352	359	PF00069	0.420
MOD_GSK3_1	360	367	PF00069	0.399
MOD_GSK3_1	42	49	PF00069	0.516
MOD_GSK3_1	420	427	PF00069	0.305
MOD_GSK3_1	464	471	PF00069	0.214
MOD_GSK3_1	585	592	PF00069	0.244
MOD_LATS_1	152	158	PF00433	0.488
MOD_N-GLC_1	360	365	PF02516	0.420
MOD_N-GLC_1	40	45	PF02516	0.575
MOD_N-GLC_1	424	429	PF02516	0.329
MOD_NEK2_1	187	192	PF00069	0.445
MOD_NEK2_1	205	210	PF00069	0.393
MOD_NEK2_1	29	34	PF00069	0.475
MOD_NEK2_1	412	417	PF00069	0.292
MOD_NEK2_1	481	486	PF00069	0.214
MOD_NEK2_1	488	493	PF00069	0.209
MOD_NEK2_1	75	80	PF00069	0.444
MOD_NEK2_2	413	418	PF00069	0.302
MOD_NEK2_2	489	494	PF00069	0.214
MOD_PIKK_1	125	131	PF00454	0.457
MOD_PIKK_1	223	229	PF00454	0.576
MOD_PIKK_1	319	325	PF00454	0.527
MOD_PK_1	219	225	PF00069	0.615
MOD_PK_1	259	265	PF00069	0.413
MOD_PKA_1	219	225	PF00069	0.615
MOD_PKA_1	297	303	PF00069	0.640
MOD_PKA_2	219	225	PF00069	0.615
MOD_PKA_2	275	281	PF00069	0.568
MOD_PKA_2	297	303	PF00069	0.640
MOD_PKA_2	328	334	PF00069	0.542
MOD_Plk_1	257	263	PF00069	0.402
MOD_Plk_1	360	366	PF00069	0.412
MOD_Plk_2-3	195	201	PF00069	0.467
MOD_Plk_4	219	225	PF00069	0.615
MOD_Plk_4	269	275	PF00069	0.425
MOD_Plk_4	311	317	PF00069	0.496
MOD_Plk_4	464	470	PF00069	0.389
MOD_Plk_4	53	59	PF00069	0.515
MOD_Plk_4	558	564	PF00069	0.217
MOD_Plk_4	567	573	PF00069	0.209
MOD_Plk_4	61	67	PF00069	0.383
MOD_Plk_4	75	81	PF00069	0.353
MOD_ProDKin_1	40	46	PF00069	0.557
MOD_ProDKin_1	506	512	PF00069	0.214
MOD_SUMO_rev_2	376	383	PF00179	0.368
MOD_SUMO_rev_2	428	437	PF00179	0.364
MOD_SUMO_rev_2	94	99	PF00179	0.485
TRG_DiLeu_BaEn_2	200	206	PF01217	0.504
TRG_ENDOCYTIC_2	414	417	PF00928	0.306
TRG_ENDOCYTIC_2	446	449	PF00928	0.380
TRG_ENDOCYTIC_2	534	537	PF00928	0.214
TRG_ENDOCYTIC_2	554	557	PF00928	0.212
TRG_ENDOCYTIC_2	583	586	PF00928	0.238
TRG_ER_diArg_1	542	545	PF00400	0.316
TRG_ER_diArg_1	581	583	PF00400	0.234
TRG_NLS_Bipartite_1	281	301	PF00514	0.542
TRG_NLS_MonoExtC_3	549	555	PF00514	0.247
TRG_NLS_MonoExtN_4	549	554	PF00514	0.250
TRG_Pf-PMV_PEXEL_1	345	349	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WQL0	Leishmania donovani	99%	100%
A4H5L4	Leishmania braziliensis	76%	100%