Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cdc2-related kinase 12

Species:

Leishmania infantum

UniProt:

A4HTU3_LEIIN

TriTrypDb:

LINF_090008700

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 40

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 15
NetGPI	no	yes: 0, no: 15

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	3
GO:0016592	mediator complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0110165	cellular anatomical entity	1	3
GO:0140513	nuclear protein-containing complex	2	2
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

A4HTU3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTU3

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	16
GO:0006793	phosphorus metabolic process	3	16
GO:0006796	phosphate-containing compound metabolic process	4	16
GO:0006807	nitrogen compound metabolic process	2	16
GO:0008152	metabolic process	1	16
GO:0009987	cellular process	1	16
GO:0016310	phosphorylation	5	16
GO:0019538	protein metabolic process	3	16
GO:0036211	protein modification process	4	16
GO:0043170	macromolecule metabolic process	3	16
GO:0043412	macromolecule modification	4	16
GO:0044237	cellular metabolic process	2	16
GO:0044238	primary metabolic process	2	16
GO:0071704	organic substance metabolic process	2	16
GO:1901564	organonitrogen compound metabolic process	3	16
GO:0007165	signal transduction	2	1
GO:0035556	intracellular signal transduction	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0065007	biological regulation	1	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	16
GO:0003824	catalytic activity	1	16
GO:0004672	protein kinase activity	3	16
GO:0005488	binding	1	16
GO:0005524	ATP binding	5	16
GO:0016301	kinase activity	4	16
GO:0016740	transferase activity	2	16
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	16
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	16
GO:0017076	purine nucleotide binding	4	16
GO:0030554	adenyl nucleotide binding	5	16
GO:0032553	ribonucleotide binding	3	16
GO:0032555	purine ribonucleotide binding	4	16
GO:0032559	adenyl ribonucleotide binding	5	16
GO:0035639	purine ribonucleoside triphosphate binding	4	16
GO:0036094	small molecule binding	2	16
GO:0043167	ion binding	2	16
GO:0043168	anion binding	3	16
GO:0097159	organic cyclic compound binding	2	16
GO:0097367	carbohydrate derivative binding	2	16
GO:0140096	catalytic activity, acting on a protein	2	16
GO:1901265	nucleoside phosphate binding	3	16
GO:1901363	heterocyclic compound binding	2	16
GO:0004674	protein serine/threonine kinase activity	4	12
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5	2
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5	2
GO:0097472	cyclin-dependent protein kinase activity	4	2
GO:0004707	MAP kinase activity	5	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	172	174	PF00675	0.313
CLV_NRD_NRD_1	193	195	PF00675	0.210
CLV_NRD_NRD_1	26	28	PF00675	0.395
CLV_NRD_NRD_1	397	399	PF00675	0.182
CLV_NRD_NRD_1	457	459	PF00675	0.355
CLV_NRD_NRD_1	474	476	PF00675	0.504
CLV_PCSK_KEX2_1	172	174	PF00082	0.274
CLV_PCSK_KEX2_1	26	28	PF00082	0.395
CLV_PCSK_KEX2_1	397	399	PF00082	0.191
CLV_PCSK_KEX2_1	457	459	PF00082	0.314
CLV_PCSK_KEX2_1	474	476	PF00082	0.500
CLV_PCSK_KEX2_1	76	78	PF00082	0.257
CLV_PCSK_KEX2_1	85	87	PF00082	0.202
CLV_PCSK_PC1ET2_1	76	78	PF00082	0.178
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.173
CLV_PCSK_SKI1_1	10	14	PF00082	0.417
CLV_PCSK_SKI1_1	187	191	PF00082	0.484
CLV_PCSK_SKI1_1	204	208	PF00082	0.311
CLV_PCSK_SKI1_1	50	54	PF00082	0.278
CLV_PCSK_SKI1_1	85	89	PF00082	0.194
CLV_Separin_Metazoa	423	427	PF03568	0.175
DEG_SCF_FBW7_2	446	453	PF00400	0.331
DOC_CDC14_PxL_1	433	441	PF14671	0.370
DOC_CKS1_1	242	247	PF01111	0.175
DOC_CKS1_1	447	452	PF01111	0.327
DOC_MAPK_gen_1	151	160	PF00069	0.275
DOC_MAPK_gen_1	187	193	PF00069	0.336
DOC_MAPK_gen_1	194	201	PF00069	0.313
DOC_MAPK_gen_1	204	213	PF00069	0.311
DOC_MAPK_gen_1	26	35	PF00069	0.403
DOC_MAPK_gen_1	76	84	PF00069	0.279
DOC_MAPK_HePTP_8	148	160	PF00069	0.221
DOC_MAPK_MEF2A_6	151	160	PF00069	0.275
DOC_MAPK_MEF2A_6	26	35	PF00069	0.403
DOC_MAPK_RevD_3	182	195	PF00069	0.175
DOC_PP2B_LxvP_1	283	286	PF13499	0.175
DOC_PP2B_LxvP_1	425	428	PF13499	0.175
DOC_USP7_MATH_1	138	142	PF00917	0.175
DOC_USP7_MATH_1	163	167	PF00917	0.175
DOC_USP7_MATH_1	232	236	PF00917	0.229
DOC_USP7_MATH_1	302	306	PF00917	0.198
DOC_USP7_MATH_1	97	101	PF00917	0.175
DOC_USP7_UBL2_3	72	76	PF12436	0.207
DOC_WW_Pin1_4	10	15	PF00397	0.426
DOC_WW_Pin1_4	175	180	PF00397	0.233
DOC_WW_Pin1_4	20	25	PF00397	0.484
DOC_WW_Pin1_4	241	246	PF00397	0.239
DOC_WW_Pin1_4	446	451	PF00397	0.342
LIG_14-3-3_CanoR_1	304	313	PF00244	0.231
LIG_14-3-3_CanoR_1	315	323	PF00244	0.213
LIG_14-3-3_CanoR_1	8	13	PF00244	0.429
LIG_BRCT_BRCA1_1	41	45	PF00533	0.379
LIG_FHA_1	132	138	PF00498	0.175
LIG_FHA_1	162	168	PF00498	0.251
LIG_FHA_1	242	248	PF00498	0.293
LIG_FHA_1	315	321	PF00498	0.182
LIG_FHA_2	176	182	PF00498	0.175
LIG_FHA_2	260	266	PF00498	0.187
LIG_FHA_2	306	312	PF00498	0.210
LIG_FHA_2	364	370	PF00498	0.183
LIG_FHA_2	418	424	PF00498	0.243
LIG_FHA_2	429	435	PF00498	0.332
LIG_FHA_2	49	55	PF00498	0.304
LIG_FHA_2	64	70	PF00498	0.172
LIG_LIR_Apic_2	239	245	PF02991	0.292
LIG_LIR_Apic_2	249	255	PF02991	0.412
LIG_LIR_Gen_1	3	14	PF02991	0.404
LIG_LIR_Gen_1	371	380	PF02991	0.175
LIG_LIR_Gen_1	42	52	PF02991	0.334
LIG_LIR_Gen_1	441	450	PF02991	0.388
LIG_LIR_Nem_3	3	9	PF02991	0.395
LIG_LIR_Nem_3	371	377	PF02991	0.216
LIG_LIR_Nem_3	42	48	PF02991	0.458
LIG_LIR_Nem_3	441	445	PF02991	0.452
LIG_LIR_Nem_3	64	70	PF02991	0.346
LIG_NRBOX	272	278	PF00104	0.175
LIG_PCNA_yPIPBox_3	49	61	PF02747	0.281
LIG_PCNA_yPIPBox_3	98	108	PF02747	0.175
LIG_Pex14_2	368	372	PF04695	0.175
LIG_Pex14_2	380	384	PF04695	0.173
LIG_SH2_CRK	442	446	PF00017	0.411
LIG_SH2_NCK_1	162	166	PF00017	0.175
LIG_SH2_STAP1	264	268	PF00017	0.300
LIG_SH2_STAT3	149	152	PF00017	0.175
LIG_SH2_STAT5	429	432	PF00017	0.335
LIG_SH3_1	444	450	PF00018	0.362
LIG_SH3_2	447	452	PF14604	0.327
LIG_SH3_3	30	36	PF00018	0.403
LIG_SH3_3	319	325	PF00018	0.227
LIG_SH3_3	444	450	PF00018	0.364
LIG_SUMO_SIM_anti_2	155	160	PF11976	0.175
LIG_TRFH_1	281	285	PF08558	0.175
LIG_WW_1	285	288	PF00397	0.175
MOD_CDC14_SPxK_1	23	26	PF00782	0.423
MOD_CDK_SPxK_1	20	26	PF00069	0.445
MOD_CDK_SPxK_1	446	452	PF00069	0.336
MOD_CDK_SPxxK_3	20	27	PF00069	0.441
MOD_CK1_1	234	240	PF00069	0.230
MOD_CK1_1	246	252	PF00069	0.193
MOD_CK1_1	305	311	PF00069	0.200
MOD_CK1_1	314	320	PF00069	0.194
MOD_CK1_1	4	10	PF00069	0.452
MOD_CK1_1	63	69	PF00069	0.175
MOD_CK2_1	175	181	PF00069	0.175
MOD_CK2_1	212	218	PF00069	0.246
MOD_CK2_1	305	311	PF00069	0.210
MOD_CK2_1	363	369	PF00069	0.183
MOD_CK2_1	417	423	PF00069	0.272
MOD_CK2_1	48	54	PF00069	0.333
MOD_CK2_1	63	69	PF00069	0.191
MOD_CK2_1	97	103	PF00069	0.281
MOD_DYRK1A_RPxSP_1	10	14	PF00069	0.417
MOD_GlcNHglycan	236	239	PF01048	0.250
MOD_GlcNHglycan	3	6	PF01048	0.395
MOD_GlcNHglycan	303	307	PF01048	0.234
MOD_GSK3_1	232	239	PF00069	0.175
MOD_GSK3_1	39	46	PF00069	0.395
MOD_GSK3_1	4	11	PF00069	0.396
MOD_NEK2_1	1	6	PF00069	0.419
MOD_NEK2_1	258	263	PF00069	0.229
MOD_NEK2_1	388	393	PF00069	0.226
MOD_NEK2_1	438	443	PF00069	0.465
MOD_NEK2_1	89	94	PF00069	0.213
MOD_NEK2_2	97	102	PF00069	0.224
MOD_PIKK_1	138	144	PF00454	0.175
MOD_PIKK_1	17	23	PF00454	0.453
MOD_PIKK_1	397	403	PF00454	0.178
MOD_PIKK_1	469	475	PF00454	0.428
MOD_PK_1	243	249	PF00069	0.175
MOD_PKA_1	397	403	PF00069	0.175
MOD_PKA_2	314	320	PF00069	0.215
MOD_PKA_2	397	403	PF00069	0.175
MOD_PKA_2	417	423	PF00069	0.292
MOD_Plk_1	138	144	PF00069	0.175
MOD_Plk_1	43	49	PF00069	0.381
MOD_Plk_4	243	249	PF00069	0.251
MOD_Plk_4	324	330	PF00069	0.202
MOD_Plk_4	363	369	PF00069	0.291
MOD_ProDKin_1	10	16	PF00069	0.427
MOD_ProDKin_1	175	181	PF00069	0.233
MOD_ProDKin_1	20	26	PF00069	0.477
MOD_ProDKin_1	241	247	PF00069	0.239
MOD_ProDKin_1	446	452	PF00069	0.336
MOD_SUMO_rev_2	261	268	PF00179	0.175
TRG_DiLeu_BaEn_1	181	186	PF01217	0.175
TRG_DiLeu_BaLyEn_6	434	439	PF01217	0.370
TRG_ENDOCYTIC_2	374	377	PF00928	0.175
TRG_ENDOCYTIC_2	442	445	PF00928	0.417
TRG_ENDOCYTIC_2	67	70	PF00928	0.342
TRG_ER_diArg_1	25	27	PF00400	0.414
TRG_ER_diArg_1	288	291	PF00400	0.175
TRG_ER_diArg_1	397	399	PF00400	0.198
TRG_ER_diArg_1	456	458	PF00400	0.301
TRG_ER_diArg_1	474	476	PF00400	0.500
TRG_Pf-PMV_PEXEL_1	194	198	PF00026	0.286
TRG_Pf-PMV_PEXEL_1	338	342	PF00026	0.214

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2E2	Leptomonas seymouri	23%	100%
A0A0N0P407	Leptomonas seymouri	24%	100%
A0A0N0P4E3	Leptomonas seymouri	24%	71%
A0A0N0P4P4	Leptomonas seymouri	27%	100%
A0A0N1PC32	Leptomonas seymouri	26%	100%
A0A0S4IXW3	Bodo saltans	23%	100%
A0A0S4IZ59	Bodo saltans	37%	70%
A0A0S4J7C1	Bodo saltans	27%	69%
A0A0S4JCK3	Bodo saltans	22%	100%
A0A0S4JFU9	Bodo saltans	24%	93%
A0A0S4JQ66	Bodo saltans	23%	100%
A0A0S4JTQ2	Bodo saltans	23%	100%
A0A0S4JXW9	Bodo saltans	24%	100%
A0A0S4KFI2	Bodo saltans	24%	100%
A0A1X0NQM7	Trypanosomatidae	24%	100%
A0A1X0NQT9	Trypanosomatidae	23%	100%
A0A1X0NT84	Trypanosomatidae	24%	95%
A0A1X0NTI4	Trypanosomatidae	27%	69%
A0A1X0P018	Trypanosomatidae	23%	86%
A0A1X0P020	Trypanosomatidae	28%	100%
A0A1X0P3B9	Trypanosomatidae	28%	100%
A0A1X0P3X8	Trypanosomatidae	26%	100%
A0A1X0P692	Trypanosomatidae	27%	100%
A0A1X0P6E7	Trypanosomatidae	26%	100%
A0A1X0P6U6	Trypanosomatidae	24%	100%
A0A1X0P798	Trypanosomatidae	23%	100%
A0A3Q8IB74	Leishmania donovani	26%	100%
A0A3Q8IH39	Leishmania donovani	23%	100%
A0A3Q8II44	Leishmania donovani	30%	100%
A0A3Q8IPR6	Leishmania donovani	31%	100%
A0A3R7K5U6	Trypanosoma rangeli	26%	82%
A0A3R7LCG7	Trypanosoma rangeli	27%	83%
A0A3R7NAU1	Trypanosoma rangeli	22%	100%
A0A3S5H528	Leishmania donovani	25%	99%
A0A3S5H725	Leishmania donovani	29%	100%
A0A3S5IRQ5	Trypanosoma rangeli	22%	100%
A0A3S7WR45	Leishmania donovani	25%	100%
A0A3S7WRG1	Leishmania donovani	27%	100%
A0A3S7X2Z6	Leishmania donovani	25%	100%
A0A3S7X7D5	Leishmania donovani	26%	100%
A0A3S7X933	Leishmania donovani	25%	100%
A0A3S7XA45	Leishmania donovani	26%	100%
A0A422N878	Trypanosoma rangeli	24%	91%
A0A422N9H2	Trypanosoma rangeli	23%	100%
A0A422NYI3	Trypanosoma rangeli	28%	75%
A0A422P3I6	Trypanosoma rangeli	27%	100%
A0A451EJH2	Leishmania donovani	23%	100%
A1CL96	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	26%	100%
A1D624	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	26%	100%
A2QU77	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	100%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	24%	100%
A3LUB9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	24%	100%
A4H3D2	Leishmania braziliensis	24%	86%
A4H4A1	Leishmania braziliensis	32%	100%
A4H641	Leishmania braziliensis	25%	93%
A4H9D1	Leishmania braziliensis	29%	100%
A4H9X5	Leishmania braziliensis	28%	100%
A4HAC8	Leishmania braziliensis	27%	100%
A4HFI2	Leishmania braziliensis	30%	100%
A4HMJ3	Leishmania braziliensis	25%	100%
A4HNG3	Leishmania braziliensis	26%	100%
A4HRN3	Leishmania infantum	23%	87%
A4HRT2	Leishmania infantum	25%	99%
A4HUC8	Leishmania infantum	24%	100%
A4HUG1	Leishmania infantum	25%	89%
A4HUS3	Leishmania infantum	27%	100%
A4HXQ3	Leishmania infantum	29%	100%
A4I564	Leishmania infantum	25%	100%
A4I9H1	Leishmania infantum	26%	100%
A4IB73	Leishmania infantum	25%	100%
A4IC54	Leishmania infantum	26%	100%
A4ICA4	Leishmania infantum	30%	100%
A4QXX4	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	25%	96%
A8XA58	Caenorhabditis briggsae	27%	100%
A9S9Q8	Physcomitrium patens	24%	100%
C9ZKU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	82%
C9ZLG9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
C9ZVD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZVG3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
C9ZZI2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D0A230	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0AAS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	73%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ACB1	Leishmania major	24%	87%
E9ACG8	Leishmania major	25%	99%
E9AD33	Leishmania major	31%	100%
E9AEZ4	Leishmania major	26%	89%
E9AFX4	Leishmania major	26%	100%
E9AGS0	Leishmania infantum	26%	100%
E9AHC6	Leishmania infantum	31%	100%
E9AJJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	87%
E9AKG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9AN59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	93%
E9ANF7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ARG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AYV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B4G9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9B650	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	89%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
O08911	Mus musculus	25%	100%
O13958	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O62618	Drosophila melanogaster	23%	100%
P0C661	Caenorhabditis briggsae	22%	78%
P0CS76	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	23%	100%
P0CS77	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	23%	100%
P14681	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P34556	Caenorhabditis elegans	27%	100%
P42525	Dictyostelium discoideum	24%	90%
P45984	Homo sapiens	24%	100%
P49186	Rattus norvegicus	24%	100%
P49336	Homo sapiens	22%	100%
P51566	Arabidopsis thaliana	22%	100%
P53778	Homo sapiens	24%	100%
P54685	Dictyostelium discoideum	24%	100%
P79996	Gallus gallus	24%	100%
P90866	Caenorhabditis elegans	23%	81%
P97377	Mus musculus	28%	100%
Q00532	Homo sapiens	25%	100%
Q0CQK1	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	25%	100%
Q0J4I1	Oryza sativa subsp. japonica	27%	100%
Q0TWJ7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	26%	100%
Q12126	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
Q15759	Homo sapiens	25%	100%
Q17IE8	Aedes aegypti	23%	95%
Q1EBK0	Coccidioides immitis (strain RS)	27%	100%
Q23357	Caenorhabditis elegans	27%	72%
Q2GYV9	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	26%	93%
Q2QSL4	Oryza sativa subsp. japonica	28%	100%
Q2UC58	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	25%	100%
Q336M2	Oryza sativa subsp. japonica	28%	100%
Q336X9	Oryza sativa subsp. japonica	24%	100%
Q39025	Arabidopsis thaliana	25%	100%
Q3TZA2	Mus musculus	24%	100%
Q40517	Nicotiana tabacum	24%	100%
Q4FCZ5	Gibberella moniliformis	26%	100%
Q4P9T2	Ustilago maydis (strain 521 / FGSC 9021)	24%	67%
Q4Q0B0	Leishmania major	31%	100%
Q4QDK3	Leishmania major	26%	100%
Q4QE15	Leishmania major	29%	100%
Q4QH69	Leishmania major	27%	100%
Q4QHG6	Leishmania major	25%	89%
Q4QJE7	Leishmania major	32%	100%
Q4R8T9	Macaca fascicularis	26%	81%
Q4WYR6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q54LR6	Dictyostelium discoideum	25%	79%
Q54Y06	Dictyostelium discoideum	24%	75%
Q55FJ6	Dictyostelium discoideum	22%	94%
Q55GS4	Dictyostelium discoideum	28%	100%
Q5AHK2	Candida albicans (strain SC5314 / ATCC MYA-2876)	25%	79%
Q5BAE1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	27%	100%
Q5MAI5	Homo sapiens	24%	100%
Q5R754	Pongo abelii	25%	97%
Q5SN53	Oryza sativa subsp. japonica	26%	84%
Q62726	Rattus norvegicus	25%	76%
Q63538	Rattus norvegicus	24%	100%
Q66HE7	Rattus norvegicus	25%	100%
Q6AXJ9	Danio rerio	25%	100%
Q6BM25	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	100%
Q6CCB0	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	100%
Q6CR51	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	22%	81%
Q6Z437	Oryza sativa subsp. japonica	25%	100%
Q6Z8C8	Oryza sativa subsp. japonica	26%	100%
Q75KK8	Oryza sativa subsp. japonica	25%	88%
Q8CEQ0	Mus musculus	25%	100%
Q8IVW4	Homo sapiens	26%	81%
Q8JH47	Danio rerio	22%	100%
Q8R3L8	Mus musculus	22%	100%
Q92772	Homo sapiens	25%	97%
Q95YH0	Dictyostelium discoideum	26%	100%
Q966Y3	Suberites domuncula	23%	100%
Q9C9U4	Arabidopsis thaliana	24%	83%
Q9FGW5	Arabidopsis thaliana	29%	78%
Q9JKV2	Mus musculus	25%	76%
Q9JM01	Rattus norvegicus	27%	81%
Q9QUK0	Mus musculus	25%	84%
Q9TTK0	Oryctolagus cuniculus	24%	84%
Q9TVL3	Caenorhabditis elegans	28%	100%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	100%
Q9WTU6	Mus musculus	25%	100%
Q9WUI1	Mus musculus	25%	100%
V5BA65	Trypanosoma cruzi	23%	100%
V5BCX5	Trypanosoma cruzi	22%	100%
V5BPE2	Trypanosoma cruzi	26%	100%
V5BR38	Trypanosoma cruzi	23%	98%
V5D488	Trypanosoma cruzi	25%	100%
V5DA09	Trypanosoma cruzi	22%	100%
V5DCD4	Trypanosoma cruzi	26%	81%
V5DIC3	Trypanosoma cruzi	24%	79%