LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
protein kinase - putative
Species:
Leishmania infantum
UniProt:
A4HTL4_LEIIN
TriTrypDb:
LINF_080011800
Length:
1359

Annotations

LeishMANIAdb annotations

A typical Kinetoplastid receptor kinase, belonging to the STE11 kinase family (MAP3K). Very tentatively required for stress response and / or developmental stage regulation. Expanded in many kinetoplastid groups, but especially in Leishmaniids.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 14
NetGPI no yes: 0, no: 15
Cellular components
Term Name Level Count
GO:0016020 membrane 2 12
GO:0110165 cellular anatomical entity 1 12

Expansion

Sequence features

A4HTL4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HTL4

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 15
GO:0006793 phosphorus metabolic process 3 16
GO:0006796 phosphate-containing compound metabolic process 4 16
GO:0006807 nitrogen compound metabolic process 2 15
GO:0008152 metabolic process 1 16
GO:0009987 cellular process 1 16
GO:0016310 phosphorylation 5 16
GO:0019538 protein metabolic process 3 15
GO:0036211 protein modification process 4 15
GO:0043170 macromolecule metabolic process 3 15
GO:0043412 macromolecule modification 4 15
GO:0044237 cellular metabolic process 2 16
GO:0044238 primary metabolic process 2 15
GO:0071704 organic substance metabolic process 2 15
GO:1901564 organonitrogen compound metabolic process 3 15
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 15
GO:0003824 catalytic activity 1 16
GO:0004672 protein kinase activity 3 16
GO:0005488 binding 1 15
GO:0005524 ATP binding 5 15
GO:0016301 kinase activity 4 16
GO:0016740 transferase activity 2 16
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 16
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 16
GO:0017076 purine nucleotide binding 4 15
GO:0030554 adenyl nucleotide binding 5 15
GO:0032553 ribonucleotide binding 3 15
GO:0032555 purine ribonucleotide binding 4 15
GO:0032559 adenyl ribonucleotide binding 5 15
GO:0035639 purine ribonucleoside triphosphate binding 4 15
GO:0036094 small molecule binding 2 15
GO:0043167 ion binding 2 15
GO:0043168 anion binding 3 15
GO:0097159 organic cyclic compound binding 2 15
GO:0097367 carbohydrate derivative binding 2 15
GO:0140096 catalytic activity, acting on a protein 2 16
GO:1901265 nucleoside phosphate binding 3 15
GO:1901363 heterocyclic compound binding 2 15
GO:0004674 protein serine/threonine kinase activity 4 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 346 350 PF00656 0.377
CLV_C14_Caspase3-7 720 724 PF00656 0.567
CLV_NRD_NRD_1 1034 1036 PF00675 0.487
CLV_NRD_NRD_1 1090 1092 PF00675 0.413
CLV_NRD_NRD_1 1323 1325 PF00675 0.311
CLV_NRD_NRD_1 542 544 PF00675 0.455
CLV_NRD_NRD_1 65 67 PF00675 0.454
CLV_NRD_NRD_1 903 905 PF00675 0.589
CLV_NRD_NRD_1 944 946 PF00675 0.503
CLV_NRD_NRD_1 981 983 PF00675 0.536
CLV_PCSK_KEX2_1 1090 1092 PF00082 0.419
CLV_PCSK_KEX2_1 1107 1109 PF00082 0.319
CLV_PCSK_KEX2_1 1323 1325 PF00082 0.315
CLV_PCSK_KEX2_1 903 905 PF00082 0.589
CLV_PCSK_KEX2_1 944 946 PF00082 0.505
CLV_PCSK_KEX2_1 981 983 PF00082 0.538
CLV_PCSK_PC1ET2_1 1107 1109 PF00082 0.301
CLV_PCSK_SKI1_1 1090 1094 PF00082 0.573
CLV_PCSK_SKI1_1 1108 1112 PF00082 0.248
CLV_PCSK_SKI1_1 1148 1152 PF00082 0.319
CLV_PCSK_SKI1_1 1158 1162 PF00082 0.344
CLV_PCSK_SKI1_1 1212 1216 PF00082 0.337
CLV_PCSK_SKI1_1 1257 1261 PF00082 0.383
CLV_PCSK_SKI1_1 1297 1301 PF00082 0.292
CLV_PCSK_SKI1_1 1323 1327 PF00082 0.292
CLV_PCSK_SKI1_1 1344 1348 PF00082 0.506
CLV_PCSK_SKI1_1 302 306 PF00082 0.584
CLV_PCSK_SKI1_1 324 328 PF00082 0.669
CLV_PCSK_SKI1_1 392 396 PF00082 0.688
CLV_PCSK_SKI1_1 486 490 PF00082 0.418
CLV_PCSK_SKI1_1 66 70 PF00082 0.508
CLV_PCSK_SKI1_1 754 758 PF00082 0.527
CLV_PCSK_SKI1_1 76 80 PF00082 0.401
CLV_PCSK_SKI1_1 782 786 PF00082 0.446
CLV_Separin_Metazoa 545 549 PF03568 0.671
CLV_Separin_Metazoa 746 750 PF03568 0.664
DEG_APCC_DBOX_1 1184 1192 PF00400 0.492
DEG_APCC_DBOX_1 323 331 PF00400 0.375
DEG_APCC_DBOX_1 391 399 PF00400 0.487
DEG_APCC_DBOX_1 75 83 PF00400 0.614
DEG_COP1_1 1010 1018 PF00400 0.638
DEG_SCF_FBW7_1 957 962 PF00400 0.682
DOC_ANK_TNKS_1 1077 1084 PF00023 0.760
DOC_CKS1_1 1015 1020 PF01111 0.628
DOC_CKS1_1 1232 1237 PF01111 0.617
DOC_CKS1_1 32 37 PF01111 0.679
DOC_CKS1_1 651 656 PF01111 0.704
DOC_CYCLIN_RxL_1 1045 1054 PF00134 0.625
DOC_CYCLIN_RxL_1 1320 1329 PF00134 0.546
DOC_CYCLIN_RxL_1 299 308 PF00134 0.367
DOC_CYCLIN_yCln2_LP_2 231 237 PF00134 0.324
DOC_CYCLIN_yCln2_LP_2 434 440 PF00134 0.452
DOC_CYCLIN_yCln2_LP_2 551 557 PF00134 0.680
DOC_CYCLIN_yCln2_LP_2 897 900 PF00134 0.656
DOC_MAPK_DCC_7 548 557 PF00069 0.677
DOC_MAPK_gen_1 1153 1162 PF00069 0.458
DOC_MAPK_gen_1 177 187 PF00069 0.388
DOC_MAPK_gen_1 3 13 PF00069 0.653
DOC_MAPK_gen_1 302 312 PF00069 0.374
DOC_MAPK_gen_1 627 636 PF00069 0.654
DOC_MAPK_MEF2A_6 334 343 PF00069 0.380
DOC_MAPK_MEF2A_6 6 13 PF00069 0.654
DOC_MAPK_MEF2A_6 627 636 PF00069 0.603
DOC_MAPK_MEF2A_6 794 801 PF00069 0.738
DOC_MAPK_NFAT4_5 6 14 PF00069 0.655
DOC_PP1_RVXF_1 1156 1163 PF00149 0.520
DOC_PP1_RVXF_1 276 282 PF00149 0.346
DOC_PP2B_LxvP_1 14 17 PF13499 0.639
DOC_PP2B_LxvP_1 304 307 PF13499 0.403
DOC_PP2B_LxvP_1 434 437 PF13499 0.456
DOC_PP2B_LxvP_1 551 554 PF13499 0.695
DOC_PP2B_LxvP_1 555 558 PF13499 0.680
DOC_PP2B_LxvP_1 745 748 PF13499 0.669
DOC_PP2B_LxvP_1 897 900 PF13499 0.656
DOC_PP4_FxxP_1 481 484 PF00568 0.542
DOC_PP4_FxxP_1 651 654 PF00568 0.781
DOC_PP4_FxxP_1 987 990 PF00568 0.693
DOC_PP4_MxPP_1 44 47 PF00568 0.685
DOC_USP7_MATH_1 1051 1055 PF00917 0.699
DOC_USP7_MATH_1 1057 1061 PF00917 0.616
DOC_USP7_MATH_1 116 120 PF00917 0.407
DOC_USP7_MATH_1 2 6 PF00917 0.648
DOC_USP7_MATH_1 250 254 PF00917 0.332
DOC_USP7_MATH_1 427 431 PF00917 0.328
DOC_USP7_MATH_1 53 57 PF00917 0.699
DOC_USP7_MATH_1 599 603 PF00917 0.792
DOC_USP7_MATH_1 645 649 PF00917 0.642
DOC_USP7_MATH_1 659 663 PF00917 0.542
DOC_USP7_MATH_1 769 773 PF00917 0.721
DOC_USP7_MATH_1 820 824 PF00917 0.649
DOC_USP7_MATH_1 847 851 PF00917 0.612
DOC_USP7_MATH_1 974 978 PF00917 0.713
DOC_WW_Pin1_4 1014 1019 PF00397 0.633
DOC_WW_Pin1_4 1037 1042 PF00397 0.727
DOC_WW_Pin1_4 1090 1095 PF00397 0.767
DOC_WW_Pin1_4 1221 1226 PF00397 0.529
DOC_WW_Pin1_4 1231 1236 PF00397 0.529
DOC_WW_Pin1_4 17 22 PF00397 0.657
DOC_WW_Pin1_4 27 32 PF00397 0.677
DOC_WW_Pin1_4 58 63 PF00397 0.720
DOC_WW_Pin1_4 605 610 PF00397 0.820
DOC_WW_Pin1_4 622 627 PF00397 0.637
DOC_WW_Pin1_4 650 655 PF00397 0.719
DOC_WW_Pin1_4 955 960 PF00397 0.672
LIG_14-3-3_CanoR_1 1035 1042 PF00244 0.641
LIG_14-3-3_CanoR_1 1156 1161 PF00244 0.461
LIG_14-3-3_CanoR_1 124 129 PF00244 0.450
LIG_14-3-3_CanoR_1 1257 1264 PF00244 0.475
LIG_14-3-3_CanoR_1 1323 1329 PF00244 0.555
LIG_14-3-3_CanoR_1 180 185 PF00244 0.360
LIG_14-3-3_CanoR_1 420 426 PF00244 0.360
LIG_14-3-3_CanoR_1 57 62 PF00244 0.785
LIG_14-3-3_CanoR_1 582 588 PF00244 0.682
LIG_14-3-3_CanoR_1 6 10 PF00244 0.652
LIG_14-3-3_CanoR_1 631 635 PF00244 0.666
LIG_14-3-3_CanoR_1 981 991 PF00244 0.778
LIG_Actin_WH2_2 470 488 PF00022 0.383
LIG_Actin_WH2_2 773 788 PF00022 0.637
LIG_APCC_ABBA_1 369 374 PF00400 0.358
LIG_BIR_III_2 1079 1083 PF00653 0.705
LIG_BIR_III_2 349 353 PF00653 0.369
LIG_BIR_III_4 203 207 PF00653 0.383
LIG_BRCT_BRCA1_1 1158 1162 PF00533 0.480
LIG_BRCT_BRCA1_1 410 414 PF00533 0.408
LIG_BRCT_BRCA1_1 469 473 PF00533 0.337
LIG_BRCT_BRCA1_1 647 651 PF00533 0.800
LIG_Clathr_ClatBox_1 1244 1248 PF01394 0.481
LIG_Clathr_ClatBox_1 1325 1329 PF01394 0.492
LIG_deltaCOP1_diTrp_1 83 93 PF00928 0.571
LIG_eIF4E_1 255 261 PF01652 0.344
LIG_EVH1_1 1232 1236 PF00568 0.475
LIG_FHA_1 1008 1014 PF00498 0.751
LIG_FHA_1 151 157 PF00498 0.520
LIG_FHA_1 160 166 PF00498 0.267
LIG_FHA_1 219 225 PF00498 0.423
LIG_FHA_1 376 382 PF00498 0.471
LIG_FHA_1 433 439 PF00498 0.342
LIG_FHA_1 487 493 PF00498 0.586
LIG_FHA_1 554 560 PF00498 0.699
LIG_FHA_1 680 686 PF00498 0.606
LIG_FHA_1 711 717 PF00498 0.650
LIG_FHA_1 773 779 PF00498 0.768
LIG_FHA_2 1038 1044 PF00498 0.582
LIG_FHA_2 1258 1264 PF00498 0.615
LIG_FHA_2 1333 1339 PF00498 0.519
LIG_FHA_2 1351 1357 PF00498 0.663
LIG_FHA_2 327 333 PF00498 0.421
LIG_FHA_2 361 367 PF00498 0.379
LIG_GBD_Chelix_1 339 347 PF00786 0.530
LIG_GBD_Chelix_1 471 479 PF00786 0.349
LIG_LIR_Apic_2 1220 1225 PF02991 0.617
LIG_LIR_Apic_2 648 654 PF02991 0.789
LIG_LIR_Apic_2 985 990 PF02991 0.693
LIG_LIR_Gen_1 1159 1170 PF02991 0.490
LIG_LIR_Gen_1 448 458 PF02991 0.435
LIG_LIR_Gen_1 586 597 PF02991 0.804
LIG_LIR_Gen_1 658 668 PF02991 0.583
LIG_LIR_Gen_1 83 94 PF02991 0.638
LIG_LIR_Gen_1 867 877 PF02991 0.633
LIG_LIR_Gen_1 937 947 PF02991 0.656
LIG_LIR_Nem_3 103 109 PF02991 0.482
LIG_LIR_Nem_3 1060 1066 PF02991 0.675
LIG_LIR_Nem_3 1159 1165 PF02991 0.490
LIG_LIR_Nem_3 448 454 PF02991 0.414
LIG_LIR_Nem_3 470 476 PF02991 0.518
LIG_LIR_Nem_3 586 592 PF02991 0.753
LIG_LIR_Nem_3 658 663 PF02991 0.589
LIG_LIR_Nem_3 83 89 PF02991 0.638
LIG_LIR_Nem_3 882 887 PF02991 0.529
LIG_LIR_Nem_3 937 942 PF02991 0.645
LIG_LYPXL_yS_3 1154 1157 PF13949 0.548
LIG_LYPXL_yS_3 993 996 PF13949 0.726
LIG_MYND_1 895 899 PF01753 0.767
LIG_NRBOX 1146 1152 PF00104 0.560
LIG_NRBOX 165 171 PF00104 0.348
LIG_PCNA_yPIPBox_3 1340 1350 PF02747 0.563
LIG_PCNA_yPIPBox_3 453 466 PF02747 0.292
LIG_Pex14_1 86 90 PF04695 0.432
LIG_Pex14_2 89 93 PF04695 0.335
LIG_RPA_C_Fungi 667 679 PF08784 0.481
LIG_RPA_C_Fungi 846 858 PF08784 0.460
LIG_SH2_CRK 106 110 PF00017 0.444
LIG_SH2_CRK 1242 1246 PF00017 0.305
LIG_SH2_CRK 293 297 PF00017 0.396
LIG_SH2_CRK 301 305 PF00017 0.483
LIG_SH2_GRB2like 223 226 PF00017 0.401
LIG_SH2_GRB2like 292 295 PF00017 0.334
LIG_SH2_GRB2like 440 443 PF00017 0.362
LIG_SH2_NCK_1 263 267 PF00017 0.386
LIG_SH2_PTP2 589 592 PF00017 0.587
LIG_SH2_SRC 173 176 PF00017 0.432
LIG_SH2_SRC 440 443 PF00017 0.362
LIG_SH2_STAP1 1127 1131 PF00017 0.361
LIG_SH2_STAP1 263 267 PF00017 0.363
LIG_SH2_STAT5 1063 1066 PF00017 0.490
LIG_SH2_STAT5 1222 1225 PF00017 0.298
LIG_SH2_STAT5 223 226 PF00017 0.494
LIG_SH2_STAT5 263 266 PF00017 0.398
LIG_SH2_STAT5 380 383 PF00017 0.590
LIG_SH2_STAT5 428 431 PF00017 0.603
LIG_SH2_STAT5 440 443 PF00017 0.369
LIG_SH2_STAT5 451 454 PF00017 0.464
LIG_SH2_STAT5 480 483 PF00017 0.492
LIG_SH2_STAT5 589 592 PF00017 0.714
LIG_SH2_STAT5 90 93 PF00017 0.345
LIG_SH3_1 1078 1084 PF00018 0.716
LIG_SH3_3 1010 1016 PF00018 0.704
LIG_SH3_3 1078 1084 PF00018 0.716
LIG_SH3_3 1092 1098 PF00018 0.507
LIG_SH3_3 1230 1236 PF00018 0.297
LIG_SH3_3 383 389 PF00018 0.448
LIG_SH3_3 40 46 PF00018 0.617
LIG_SH3_3 444 450 PF00018 0.431
LIG_SH3_3 589 595 PF00018 0.644
LIG_SH3_3 745 751 PF00018 0.590
LIG_SH3_3 940 946 PF00018 0.569
LIG_SH3_3 988 994 PF00018 0.581
LIG_SUMO_SIM_anti_2 162 167 PF11976 0.360
LIG_SUMO_SIM_anti_2 708 715 PF11976 0.460
LIG_SUMO_SIM_par_1 1048 1054 PF11976 0.512
LIG_SUMO_SIM_par_1 1134 1140 PF11976 0.351
LIG_SUMO_SIM_par_1 1324 1329 PF11976 0.321
LIG_SUMO_SIM_par_1 183 188 PF11976 0.475
LIG_SUMO_SIM_par_1 465 470 PF11976 0.424
LIG_TRAF2_1 1353 1356 PF00917 0.692
LIG_TRAF2_1 697 700 PF00917 0.581
LIG_TYR_ITIM 104 109 PF00017 0.442
LIG_TYR_ITIM 1064 1069 PF00017 0.525
LIG_TYR_ITIM 299 304 PF00017 0.500
LIG_TYR_ITIM 587 592 PF00017 0.598
LIG_TYR_ITIM 843 848 PF00017 0.742
LIG_UBA3_1 146 152 PF00899 0.424
LIG_WW_1 990 993 PF00397 0.596
MOD_CDC14_SPxK_1 30 33 PF00782 0.577
MOD_CDK_SPK_2 622 627 PF00069 0.582
MOD_CDK_SPxK_1 27 33 PF00069 0.580
MOD_CDK_SPxxK_3 17 24 PF00069 0.552
MOD_CDK_SPxxK_3 622 629 PF00069 0.591
MOD_CK1_1 1037 1043 PF00069 0.536
MOD_CK1_1 1171 1177 PF00069 0.417
MOD_CK1_1 1332 1338 PF00069 0.353
MOD_CK1_1 159 165 PF00069 0.550
MOD_CK1_1 183 189 PF00069 0.531
MOD_CK1_1 271 277 PF00069 0.497
MOD_CK1_1 384 390 PF00069 0.424
MOD_CK1_1 443 449 PF00069 0.402
MOD_CK1_1 5 11 PF00069 0.545
MOD_CK1_1 56 62 PF00069 0.558
MOD_CK1_1 602 608 PF00069 0.760
MOD_CK1_1 760 766 PF00069 0.691
MOD_CK1_1 772 778 PF00069 0.530
MOD_CK1_1 814 820 PF00069 0.580
MOD_CK1_1 909 915 PF00069 0.739
MOD_CK1_1 985 991 PF00069 0.650
MOD_CK1_1 99 105 PF00069 0.362
MOD_CK2_1 1037 1043 PF00069 0.460
MOD_CK2_1 109 115 PF00069 0.453
MOD_CK2_1 116 122 PF00069 0.397
MOD_CK2_1 1257 1263 PF00069 0.369
MOD_CK2_1 1271 1277 PF00069 0.340
MOD_CK2_1 1332 1338 PF00069 0.370
MOD_CK2_1 1350 1356 PF00069 0.554
MOD_CK2_1 326 332 PF00069 0.483
MOD_CK2_1 787 793 PF00069 0.507
MOD_GlcNHglycan 1053 1056 PF01048 0.491
MOD_GlcNHglycan 1170 1173 PF01048 0.417
MOD_GlcNHglycan 1273 1276 PF01048 0.333
MOD_GlcNHglycan 198 201 PF01048 0.486
MOD_GlcNHglycan 237 240 PF01048 0.651
MOD_GlcNHglycan 334 337 PF01048 0.397
MOD_GlcNHglycan 647 650 PF01048 0.762
MOD_GlcNHglycan 813 816 PF01048 0.724
MOD_GlcNHglycan 822 825 PF01048 0.529
MOD_GlcNHglycan 853 856 PF01048 0.438
MOD_GlcNHglycan 908 911 PF01048 0.604
MOD_GlcNHglycan 970 973 PF01048 0.769
MOD_GlcNHglycan 976 979 PF01048 0.633
MOD_GSK3_1 1217 1224 PF00069 0.373
MOD_GSK3_1 1267 1274 PF00069 0.328
MOD_GSK3_1 210 217 PF00069 0.558
MOD_GSK3_1 27 34 PF00069 0.654
MOD_GSK3_1 380 387 PF00069 0.471
MOD_GSK3_1 5 12 PF00069 0.555
MOD_GSK3_1 52 59 PF00069 0.608
MOD_GSK3_1 599 606 PF00069 0.696
MOD_GSK3_1 667 674 PF00069 0.566
MOD_GSK3_1 756 763 PF00069 0.564
MOD_GSK3_1 847 854 PF00069 0.512
MOD_GSK3_1 955 962 PF00069 0.647
MOD_GSK3_1 96 103 PF00069 0.426
MOD_GSK3_1 964 971 PF00069 0.581
MOD_N-GLC_1 1314 1319 PF02516 0.281
MOD_N-GLC_1 1342 1347 PF02516 0.419
MOD_N-GLC_1 214 219 PF02516 0.590
MOD_N-GLC_1 224 229 PF02516 0.469
MOD_N-GLC_1 244 249 PF02516 0.558
MOD_N-GLC_1 308 313 PF02516 0.466
MOD_N-GLC_1 343 348 PF02516 0.440
MOD_N-GLC_1 384 389 PF02516 0.457
MOD_N-GLC_1 492 497 PF02516 0.386
MOD_N-GLC_1 643 648 PF02516 0.477
MOD_NEK2_1 1002 1007 PF00069 0.436
MOD_NEK2_1 1125 1130 PF00069 0.320
MOD_NEK2_1 1192 1197 PF00069 0.321
MOD_NEK2_1 1281 1286 PF00069 0.298
MOD_NEK2_1 214 219 PF00069 0.383
MOD_NEK2_1 235 240 PF00069 0.437
MOD_NEK2_1 353 358 PF00069 0.507
MOD_NEK2_1 381 386 PF00069 0.499
MOD_NEK2_1 454 459 PF00069 0.482
MOD_NEK2_1 492 497 PF00069 0.560
MOD_NEK2_1 667 672 PF00069 0.678
MOD_NEK2_1 756 761 PF00069 0.679
MOD_NEK2_1 9 14 PF00069 0.581
MOD_NEK2_1 983 988 PF00069 0.652
MOD_NEK2_2 1143 1148 PF00069 0.373
MOD_NEK2_2 116 121 PF00069 0.434
MOD_NEK2_2 145 150 PF00069 0.383
MOD_NEK2_2 360 365 PF00069 0.425
MOD_NEK2_2 427 432 PF00069 0.355
MOD_PIKK_1 1125 1131 PF00454 0.313
MOD_PIKK_1 1248 1254 PF00454 0.305
MOD_PIKK_1 150 156 PF00454 0.446
MOD_PIKK_1 261 267 PF00454 0.375
MOD_PIKK_1 313 319 PF00454 0.459
MOD_PIKK_1 440 446 PF00454 0.395
MOD_PIKK_1 611 617 PF00454 0.636
MOD_PK_1 1156 1162 PF00069 0.257
MOD_PK_1 161 167 PF00069 0.371
MOD_PK_1 180 186 PF00069 0.254
MOD_PKA_2 1034 1040 PF00069 0.530
MOD_PKA_2 123 129 PF00069 0.562
MOD_PKA_2 1267 1273 PF00069 0.373
MOD_PKA_2 1332 1338 PF00069 0.429
MOD_PKA_2 196 202 PF00069 0.487
MOD_PKA_2 2 8 PF00069 0.537
MOD_PKA_2 547 553 PF00069 0.686
MOD_PKA_2 56 62 PF00069 0.595
MOD_PKA_2 630 636 PF00069 0.505
MOD_PKA_2 671 677 PF00069 0.507
MOD_PKB_1 677 685 PF00069 0.436
MOD_Plk_1 1102 1108 PF00069 0.234
MOD_Plk_1 1314 1320 PF00069 0.281
MOD_Plk_1 132 138 PF00069 0.412
MOD_Plk_1 1342 1348 PF00069 0.425
MOD_Plk_1 159 165 PF00069 0.544
MOD_Plk_1 214 220 PF00069 0.535
MOD_Plk_1 308 314 PF00069 0.503
MOD_Plk_1 343 349 PF00069 0.544
MOD_Plk_1 398 404 PF00069 0.443
MOD_Plk_1 486 492 PF00069 0.419
MOD_Plk_1 559 565 PF00069 0.609
MOD_Plk_1 757 763 PF00069 0.683
MOD_Plk_1 772 778 PF00069 0.486
MOD_Plk_2-3 710 716 PF00069 0.517
MOD_Plk_2-3 787 793 PF00069 0.507
MOD_Plk_4 1314 1320 PF00069 0.332
MOD_Plk_4 1342 1348 PF00069 0.425
MOD_Plk_4 145 151 PF00069 0.387
MOD_Plk_4 161 167 PF00069 0.439
MOD_Plk_4 218 224 PF00069 0.497
MOD_Plk_4 467 473 PF00069 0.355
MOD_Plk_4 583 589 PF00069 0.691
MOD_Plk_4 630 636 PF00069 0.525
MOD_Plk_4 659 665 PF00069 0.441
MOD_Plk_4 671 677 PF00069 0.469
MOD_Plk_4 730 736 PF00069 0.504
MOD_Plk_4 757 763 PF00069 0.683
MOD_Plk_4 787 793 PF00069 0.536
MOD_Plk_4 9 15 PF00069 0.560
MOD_ProDKin_1 1014 1020 PF00069 0.514
MOD_ProDKin_1 1037 1043 PF00069 0.649
MOD_ProDKin_1 1090 1096 PF00069 0.705
MOD_ProDKin_1 1221 1227 PF00069 0.373
MOD_ProDKin_1 1231 1237 PF00069 0.373
MOD_ProDKin_1 17 23 PF00069 0.553
MOD_ProDKin_1 27 33 PF00069 0.579
MOD_ProDKin_1 58 64 PF00069 0.639
MOD_ProDKin_1 605 611 PF00069 0.780
MOD_ProDKin_1 622 628 PF00069 0.521
MOD_ProDKin_1 650 656 PF00069 0.628
MOD_ProDKin_1 955 961 PF00069 0.578
MOD_SUMO_rev_2 1263 1273 PF00179 0.305
MOD_SUMO_rev_2 1338 1346 PF00179 0.431
TRG_DiLeu_BaEn_1 1277 1282 PF01217 0.480
TRG_DiLeu_BaEn_1 487 492 PF01217 0.418
TRG_DiLeu_BaEn_2 532 538 PF01217 0.575
TRG_DiLeu_BaLyEn_6 1105 1110 PF01217 0.401
TRG_DiLeu_BaLyEn_6 1197 1202 PF01217 0.311
TRG_DiLeu_BaLyEn_6 1321 1326 PF01217 0.321
TRG_DiLeu_BaLyEn_6 204 209 PF01217 0.366
TRG_DiLeu_BaLyEn_6 349 354 PF01217 0.399
TRG_DiLeu_LyEn_5 487 492 PF01217 0.418
TRG_ENDOCYTIC_2 1029 1032 PF00928 0.447
TRG_ENDOCYTIC_2 106 109 PF00928 0.365
TRG_ENDOCYTIC_2 1066 1069 PF00928 0.617
TRG_ENDOCYTIC_2 1154 1157 PF00928 0.496
TRG_ENDOCYTIC_2 1242 1245 PF00928 0.337
TRG_ENDOCYTIC_2 179 182 PF00928 0.454
TRG_ENDOCYTIC_2 301 304 PF00928 0.485
TRG_ENDOCYTIC_2 451 454 PF00928 0.509
TRG_ENDOCYTIC_2 589 592 PF00928 0.682
TRG_ENDOCYTIC_2 845 848 PF00928 0.601
TRG_ENDOCYTIC_2 90 93 PF00928 0.388
TRG_ENDOCYTIC_2 993 996 PF00928 0.681
TRG_ER_diArg_1 1089 1091 PF00400 0.481
TRG_ER_diArg_1 1323 1325 PF00400 0.321
TRG_ER_diArg_1 277 280 PF00400 0.397
TRG_ER_diArg_1 676 679 PF00400 0.458
TRG_ER_diArg_1 902 904 PF00400 0.721
TRG_ER_diArg_1 943 945 PF00400 0.633
TRG_ER_diArg_1 980 982 PF00400 0.688
TRG_NES_CRM1_1 140 154 PF08389 0.412
TRG_Pf-PMV_PEXEL_1 111 115 PF00026 0.453
TRG_Pf-PMV_PEXEL_1 118 122 PF00026 0.397
TRG_Pf-PMV_PEXEL_1 1200 1204 PF00026 0.281
TRG_Pf-PMV_PEXEL_1 1324 1329 PF00026 0.401
TRG_Pf-PMV_PEXEL_1 529 533 PF00026 0.464
TRG_Pf-PMV_PEXEL_1 754 758 PF00026 0.538

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IG80 Leishmania donovani 44% 99%
A0A3S7WQ86 Leishmania donovani 99% 100%
A0A3S7X4L0 Leishmania donovani 44% 100%
A4HJG2 Leishmania braziliensis 42% 100%
A4HJG7 Leishmania braziliensis 44% 100%
A4I6V7 Leishmania infantum 44% 99%
A4I6V8 Leishmania infantum 44% 100%
C9ZPJ9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 21% 100%
E9AME5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
E9B1Y1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 100%
E9B1Y2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 100%
Q4Q678 Leishmania major 44% 100%
Q4Q679 Leishmania major 43% 98%
Q4QIA3 Leishmania major 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS